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Select item 111094831.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102333683.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 100361164.

Structural basis for the Rad6 activation by the Bre1 N-terminal domain

Meng Shi, Jiaqi Zhao, Simin Zhang, Wei Huang, Mengfei Li, Xue Bai, Wenxue Zhang, Kai Zhang, Xuefeng Chen, Song Xiang

eLife. 2023; 12: e84157. Published online 2023 Mar 13. doi: 10.7554/eLife.84157

PMCID:: PMC10036116

Abstract Article PDF–7.0M

Select item 99922695.

The Ufd1 cofactor determines the linkage specificity of polyubiquitin chain engagement by the AAA+ ATPase Cdc48

Cameron Williams, Ken C Dong, Connor Arkinson, Andreas Martin

Mol Cell. Author manuscript; available in PMC 2024 Mar 2.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 759–769.e7. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.016

PMCID:: PMC9992269

Abstract Article PDF–1.3M

Select item 98319826.

Decoding of the ubiquitin code for clearance of colliding ribosomes by the RQT complex

Yoshitaka Matsuo, Takayuki Uchihashi, Toshifumi Inada

Nat Commun. 2023; 14: 79. Published online 2023 Jan 10. doi: 10.1038/s41467-022-35608-4

PMCID:: PMC9831982

Abstract Article PDF–2.9M

Select item 96309867.

A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans

Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor

Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136

PMCID:: PMC9630986

Abstract Article PDF–2.2M

Select item 92828578.

Adaptor linked K63 di-ubiquitin activates Nedd4/Rsp5 E3 ligase

Lu Zhu, Qing Zhang, Ciro D Cordeiro, Sudeep Banjade, Richa Sardana, Yuxin Mao, Scott D Emr

eLife. 2022; 11: e77424. Published online 2022 Jun 30. doi: 10.7554/eLife.77424

PMCID:: PMC9282857

Abstract Article PDF–4.6M

Select item 92098119.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 916991310.

The ubiquitin–proteasome system regulates meiotic chromosome organization

Xiao Yang, Meihui Song, Ying Wang, Taicong Tan, Zhongyu Tian, Binyuan Zhai, Xuan Yang, Yingjin Tan, Yanding Cao, Shaojun Dai, Shunxin Wang, Liangran Zhang

Proc Natl Acad Sci U S A. 2022 Apr 26; 119(17): e2106902119. Published online 2022 Apr 19. doi: 10.1073/pnas.2106902119

PMCID:: PMC9169913

Abstract Article PDF–2.1M

Select item 881804111.

Translocation of polyubiquitinated protein substrates by the hexameric Cdc48 ATPase

Zhejian Ji, Hao Li, Daniele Peterle, Joao A. Paulo, Scott B. Ficarro, Thomas E. Wales, Jarrod A. Marto, Steven P. Gygi, John R. Engen, Tom A. Rapoport

Mol Cell. Author manuscript; available in PMC 2023 Feb 3.

Published in final edited form as: Mol Cell. 2022 Feb 3; 82(3): 570–584.e8. Published online 2021 Dec 23. doi: 10.1016/j.molcel.2021.11.033

PMCID:: PMC8818041

Abstract Article PDF–2.5M

Select item 879822512.

Structural insights into Ubr1 mediated N-degron polyubiquitination

Man Pan, Qingyun Zheng, Tian Wang, Lujun Liang, Junxiong Mao, Chong Zuo, Ruichao Ding, Huasong Ai, Yuan Xie, Dong Si, Yuanyuan Yu, Lei Liu, Minglei Zhao

Nature. Author manuscript; available in PMC 2022 Jan 28.

Published in final edited form as: Nature. 2021 Dec; 600(7888): 334–338. Published online 2021 Nov 17. doi: 10.1038/s41586-021-04097-8

PMCID:: PMC8798225

Abstract Article PDF–4.3M

Select item 869346513.

The Ubiquitin Interacting Motif-Like Domain of Met4 Selectively Binds K48 Polyubiquitin Chains

Mark Villamil, Weidi Xiao, Clinton Yu, Lan Huang, Ping Xu, Peter Kaiser

Mol Cell Proteomics. 2022 Jan; 21(1): 100175. Published online 2021 Nov 9. doi: 10.1016/j.mcpro.2021.100175

PMCID:: PMC8693465

Abstract Article PDF–3.2M

Select item 864830014.

ANTH domains within CALM, HIP1R, and Sla2 recognize ubiquitin internalization signals

Natalya Pashkova, Lokesh Gakhar, Liping Yu, Nicholas J Schnicker, Annabel Y Minard, Stanley Winistorfer, Ivan E Johnson, Robert C Piper

eLife. 2021; 10: e72583. Published online 2021 Nov 25. doi: 10.7554/eLife.72583

PMCID:: PMC8648300

Abstract Article PDF–2.6M

Select item 858903215.

Structures of REV1 UBM2 domain complex with ubiquitin and with a small-molecule that inhibits the REV1 UBM2-ubiquitin interaction

Murugendra Vanarotti, Christy R. Grace, Darcie J. Miller, Marcelo L. Actis, Akira Inoue, Benjamin J. Evison, Sivaraja Vaithiyalingam, Aman P. Singh, Ezelle T. McDonald, Naoaki Fujii

J Mol Biol. Author manuscript; available in PMC 2021 Nov 12.

Published in final edited form as: J Mol Biol. 2018 Aug 17; 430(17): 2857–2872. Published online 2018 Jun 2. doi: 10.1016/j.jmb.2018.05.042

PMCID:: PMC8589032

Abstract Article PDF–2.2M

Select item 846130516.

Autophagy as a Mechanism for Adaptive Prediction-Mediated Emergence of Drug Resistance

Nivedita Nivedita, John D. Aitchison, Nitin S. Baliga

Front Microbiol. 2021; 12: 712631. Published online 2021 Sep 10. doi: 10.3389/fmicb.2021.712631

PMCID:: PMC8461305

Abstract Article PDF–4.8M

Select item 842120417.

Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast

Laurence Decourty, Christophe Malabat, Emmanuel Frachon, Alain Jacquier, Cosmin Saveanu

Nucleic Acids Res. 2021 Sep 7; 49(15): 8535–8555. Published online 2021 Aug 6. doi: 10.1093/nar/gkab680

PMCID:: PMC8421204

Abstract Article PDF–2.9M

Select item 840599218.

A novel recognition site for polyubiquitin and ubiquitin-like signals in an unexpected region of proteasomal subunit Rpn1

Andrew J. Boughton, Leonard Liu, Tali Lavy, Oded Kleifeld, David Fushman

J Biol Chem. 2021 Sep; 297(3): 101052. Published online 2021 Aug 6. doi: 10.1016/j.jbc.2021.101052

PMCID:: PMC8405992

Abstract Article PDF–3.6M

Select item 824085619.

Bro1 stimulates Vps4 to promote intralumenal vesicle formation during multivesicular body biogenesis

Chun-Che Tseng, Shirley Dean, Brian A. Davies, Ishara F. Azmi, Natalya Pashkova, Johanna A. Payne, Jennifer Staffenhagen, Matt West, Robert C. Piper, Greg Odorizzi, David J. Katzmann

J Cell Biol. 2021 Aug 2; 220(8): e202102070. Published online 2021 Jun 23. doi: 10.1083/jcb.202102070