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Select item 111669641.

Activation of the cell wall integrity pathway negatively regulates TORC2-Ypk1/2 signaling through blocking eisosome disassembly in Saccharomyces cerevisiae

Wataru Nomura, Yoshiharu Inoue

Commun Biol. 2024; 7: 722. Published online 2024 Jun 11. doi: 10.1038/s42003-024-06411-2

PMCID:: PMC11166964

Abstract Article PDF–3.3M

Select item 111168122.

Mitochondria–ER–PM contacts regulate mitochondrial division and PI(4)P distribution

Jason C. Casler, Clare S. Harper, Antoineen J. White, Heidi L. Anderson, Laura L. Lackner

J Cell Biol. 2024 Sep 2; 223(9): e202308144. Published online 2024 May 23. doi: 10.1083/jcb.202308144

PMCID:: PMC11116812

Abstract Article PDF–9.2M

Select item 108724773.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107988584.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107001385.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102977006.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 102922107.

Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin

Sanjeev Kumar Choudhry, Maxwell L. Neal, Song Li, Arti T. Navare, Trevor Van Eeuwen, Richard W. Wozniak, Fred D. Mast, Michael P. Rout, John D. Aitchison

J Cell Biol. 2023 Sep 4; 222(9): e202207060. Published online 2023 Jun 26. doi: 10.1083/jcb.202207060

PMCID:: PMC10292210

Abstract Article PDF–5.9M

Select item 102350868.

Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores

Ksenia Smurova, Michela Damizia, Carmela Irene, Stefania Stancari, Giovanna Berto, Giulia Perticari, Maria Giuseppina Iacovella, Ilaria D’Ambrosio, Maria Giubettini, Réginald Philippe, Chiara Baggio, Elisabetta Callegaro, Andrea Casagranda, Alessandro Corsini, Vincenzo Gentile Polese, Anna Ricci, Erik Dassi, Peter De Wulf

Nat Commun. 2023; 14: 3172. Published online 2023 Jun 1. doi: 10.1038/s41467-023-38920-9

PMCID:: PMC10235086

Abstract Article PDF–2.6M

Select item 96380289.

Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress

Michelle Harreman Lehner, Jane Walker, Kotryna Temcinaite, Anna Herlihy, Michael Taschner, Adam C. Berger, Anita H. Corbett, A. Barbara Dirac Svejstrup, Jesper Q. Svejstrup

Cell Rep. 2022 Oct 25; 41(4): 111536. Published online 2022 Oct 25. doi: 10.1016/j.celrep.2022.111536

PMCID:: PMC9638028

Abstract Article

Select item 920981110.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 916991311.

The ubiquitin–proteasome system regulates meiotic chromosome organization

Xiao Yang, Meihui Song, Ying Wang, Taicong Tan, Zhongyu Tian, Binyuan Zhai, Xuan Yang, Yingjin Tan, Yanding Cao, Shaojun Dai, Shunxin Wang, Liangran Zhang

Proc Natl Acad Sci U S A. 2022 Apr 26; 119(17): e2106902119. Published online 2022 Apr 19. doi: 10.1073/pnas.2106902119

PMCID:: PMC9169913

Abstract Article PDF–2.1M

Select item 830490012.

Phosphorylation of mRNA-Binding Proteins Puf1 and Puf2 by TORC2-Activated Protein Kinase Ypk1 Alleviates Their Repressive Effects

Henri A. Galez, Françoise M. Roelants, Sarah M. Palm, Kendra K. Reynaud, Nicholas T. Ingolia, Jeremy Thorner

Membranes (Basel) 2021 Jul; 11(7): 500. Published online 2021 Jun 30. doi: 10.3390/membranes11070500

PMCID:: PMC8304900

Abstract Article PDF–3.2M

Select item 828506113.

Phosphorylation of Pal2 by the protein kinases Kin1 and Kin2 modulates HAC1 mRNA splicing in the unfolded protein response in yeast

Chandrima Ghosh, Jagadeesh Kumar Uppala, Leena Sathe, Charlotte I. Hammond, Ashish Anshu, P Raj Pokkuluri, Benjamin E. Turk, Madhusudan Dey

Sci Signal. Author manuscript; available in PMC 2021 Nov 25.

Published in final edited form as: Sci Signal. 2021 May 25; 14(684): eaaz4401. Published online 2021 May 25. doi: 10.1126/scisignal.aaz4401

PMCID:: PMC8285061

Abstract Article PDF–2.2M

Select item 783610014.

Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ

Valentina Cappelletti, Thomas Hauser, Ilaria Piazza, Monika Pepelnjak, Liliana Malinovska, Tobias Fuhrer, Yaozong Li, Christian Dörig, Paul Boersema, Ludovic Gillet, Jan Grossbach, Aurelien Dugourd, Julio Saez-Rodriguez, Andreas Beyer, Nicola Zamboni, Amedeo Caflisch, Natalie de Souza, Paola Picotti

Cell. 2021 Jan 21; 184(2): 545–559.e22. doi: 10.1016/j.cell.2020.12.021

PMCID:: PMC7836100

Abstract Article

Select item 776057515.

TORC2-Dependent Ypk1-Mediated Phosphorylation of Lam2/Ltc4 Disrupts Its Association with the β-Propeller Protein Laf1 at Endoplasmic Reticulum-Plasma Membrane Contact Sites in the Yeast Saccharomyces cerevisiae

Magdalena Topolska, Françoise M. Roelants, Edward P. Si, Jeremy Thorner

Biomolecules. 2020 Dec; 10(12): 1598. Published online 2020 Nov 25. doi: 10.3390/biom10121598

PMCID:: PMC7760575

Abstract Article PDF–3.8M

Select item 754306816.

Conserved Ark1-related kinases function in a TORC2 signaling network

Maria Alcaide-Gavilán, Rafael Lucena, Selene Banuelos, Douglas R. Kellogg

Mol Biol Cell. 2020 Aug 15; 31(18): 2057–2069. doi: 10.1091/mbc.E19-12-0685

PMCID:: PMC7543068

Abstract Article PDF–2.0M

Select item 750740217.

Systematic analysis of bypass suppression of essential genes

Jolanda van Leeuwen, Carles Pons, Guihong Tan, Zi Yang Wang, Jing Hou, Jochen Weile, Marinella Gebbia, Wendy Liang, Ermira Shuteriqi, Zhijian Li, Maykel Lopes, Matej Ušaj, Andreia Dos Santos Lopes, Natascha van Lieshout, Chad L Myers, Frederick P Roth, Patrick Aloy, Brenda J Andrews, Charles Boone

Mol Syst Biol. 2020 Sep; 16(9): e9828. Published online 2020 Sep 17. doi: 10.15252/msb.20209828

PMCID:: PMC7507402

Abstract Article PDF–1.9M

Select item 744350718.

TOR complex 2 (TORC2) signaling and the ESCRT machinery cooperate in the protection of plasma membrane integrity in yeast

Oliver Schmidt, Yannick Weyer, Simon Sprenger, Michael A. Widerin, Sebastian Eising, Verena Baumann, Mihaela Angelova, Robbie Loewith, Christopher J. Stefan, Michael W. Hess, Florian Fröhlich, David Teis

J Biol Chem. 2020 Aug 21; 295(34): 12028–12044. Published online 2020 Jul 1. doi: 10.1074/jbc.RA120.013222

PMCID:: PMC7443507

Abstract Article PDF–3.8M

Select item 715498219.

Pkh1p-Ypk1p and Pkh1p-Sch9p Pathways Are Activated by Acetic Acid to Induce a Mitochondrial-Dependent Regulated Cell Death

António Rego, Filipa Mendes, Vítor Costa, Susana Rodrigues Chaves, Manuela Côrte-Real

Oxid Med Cell Longev. 2020; 2020: 7095078. Published online 2020 Apr 2. doi: 10.1155/2020/7095078

PMCID:: PMC7154982

Abstract Article PDF–992K

Select item 712447220.

Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9

Michael Plank, Mariya Perepelkina, Markus Müller, Stefania Vaga, Xiaoming Zou, Clélia Bourgoint, Marina Berti, Jacques Saarbach, Steven Haesendonckx, Nicolas Winssinger, Ruedi Aebersold, Robbie Loewith

Mol Cell Proteomics. 2020 Apr; 19(4): 655–671. Published online 2020 Feb 26. doi: 10.1074/mcp.RA120.001955