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Select item 111370271.

Acute depletion of BRG1 reveals its primary function as an activator of transcription

Gang Ren, Wai Lim Ku, Guangzhe Ge, Jackson A. Hoffman, Jee Youn Kang, Qingsong Tang, Kairong Cui, Yong He, Yukun Guan, Bin Gao, Chengyu Liu, Trevor K. Archer, Keji Zhao

Nat Commun. 2024; 15: 4561. Published online 2024 May 29. doi: 10.1038/s41467-024-48911-z

PMCID:: PMC11137027

Abstract Article PDF–4.1M

Select item 109040572.

Stromal Pbrm1 mediates chromatin remodeling necessary for embryo implantation in the mouse uterus

Qiliang Xin, Iris Feng, Guoyun Yu, Jurrien Dean

J Clin Invest. 2024 Mar 1; 134(5): e174194. Published online 2024 Mar 1. doi: 10.1172/JCI174194

PMCID:: PMC10904057

Abstract Article PDF–18M

Select item 108350433.

Dancr-BRG1 regulates Nfatc1 transcription and Pgc1β-dependent metabolic shifts in osteoclastogenesis

Zheng Zhang, Yichen Meng, Tao Lin, Zhanrong Zhang, Zhengbo Tao, Haozan Yin, Fu Yang, Xuhui Zhou

Proc Natl Acad Sci U S A. 2024 Jan 30; 121(5): e2313656121. Published online 2024 Jan 22. doi: 10.1073/pnas.2313656121

PMCID:: PMC10835043

Abstract Article PDF–13M

Select item 107569324.

SMARCA4 mutation causes human otosclerosis and a similar phenotype in mice

Max Drabkin, Matan M. Jean, Yael Noy, Daniel Halperin, Yuval Yogev, Ohad Wormser, Regina Proskorovsky-Ohayon, Vadim Dolgin, Noam Levaot, Vlad Brumfeld, Shira Ovadia, Mor Kishner, Udi Kazenell, Karen B. Avraham, Ilan Shelef, Ohad S. Birk

J Med Genet. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: J Med Genet. 2024 Jan 19; 61(2): 117–124. Published online 2024 Jan 19. doi: 10.1136/jmg-2023-109264

PMCID:: PMC10756932

Abstract Article PDF–923K

Select item 106886835.

Hepatocellular Brg1 promotes CCl4-induced liver inflammation, ECM accumulation and fibrosis in mice

Baocai Wang, Benedikt Kaufmann, Carolin Mogler, Suyang Zhong, Yuhan Yin, Zhangjun Cheng, Roland M. Schmid, Helmut Friess, Norbert Hüser, Guido von Figura, Daniel Hartmann

PLoS One. 2023; 18(11): e0294257. Published online 2023 Nov 30. doi: 10.1371/journal.pone.0294257

PMCID:: PMC10688683

Abstract Article PDF–1.5M

Select item 106213156.

MYC overexpression and SMARCA4 loss cooperate to drive medulloblastoma formation in mice

Carolin Göbel, Shweta Godbole, Melanie Schoof, Dörthe Holdhof, Catena Kresbach, Carolin Loose, Julia Neumann, Ulrich Schüller

Acta Neuropathol Commun. 2023; 11: 174. Published online 2023 Nov 2. doi: 10.1186/s40478-023-01654-2

PMCID:: PMC10621315

Abstract Article PDF–5.1M

Select item 105102677.

Shuting Li, Congwei Luo, Sijia Chen, Yiyi Zhuang, Yue Ji, Yiqun Zeng, Yao Zeng, Xiaoyang He, Jing Xiao, Huizhen Wang, Xiaowen Chen, Haibo Long, Fenfen Peng

J Transl Med. 2023; 21: 639. Published online 2023 Sep 19. doi: 10.1186/s12967-023-04469-w

PMCID:: PMC10510267

Abstract Article PDF–3.0M

Select item 105064138.

Smarca4 deficiency induces Pttg1 oncogene upregulation and hyperproliferation of tubular and interstitial cells during kidney development

Jinshu Xu, Xianxiao Zhou, Ting Zhang, Bin Zhang, Pin-Xian Xu

Front Cell Dev Biol. 2023; 11: 1233317. Published online 2023 Sep 4. doi: 10.3389/fcell.2023.1233317

PMCID:: PMC10506413

Abstract Article PDF–7.2M

Select item 104820079.

SWI/SNF complexes are required for retinal pigmented epithelium differentiation and for the inhibition of cell proliferation and neural differentiation programs

Shai Ovadia, Guizhong Cui, Ran Elkon, Mazal Cohen-Gulkar, Nitay Zuk-Bar, Tran Tuoc, Naihe Jing, Ruth Ashery-Padan

Development. 2023 Aug 15; 150(16): dev201488. Published online 2023 Aug 21. doi: 10.1242/dev.201488

PMCID:: PMC10482007

Abstract Article

Select item 1040428610.

Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation

Cornelis J. Boogerd, Ilaria Perini, Eirini Kyriakopoulou, Su Ji Han, Phit La, Britt van der Swaan, Jari B. Berkhout, Danielle Versteeg, Jantine Monshouwer-Kloots, Eva van Rooij

Nat Commun. 2023; 14: 4716. Published online 2023 Aug 5. doi: 10.1038/s41467-023-40203-2

PMCID:: PMC10404286

Abstract Article PDF–3.4M

Select item 1028414011.

Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1

Wei Shi, Angel P. Scialdone, James I. Emerson, Liu Mei, Lauren K. Wasson, Haley A. Davies, Christine E. Seidman, Jonathan G. Seidman, Jeanette G. Cook, Frank L. Conlon

Circ Res. 2023 Jun 23; 133(1): 48–67. Published online 2023 May 31. doi: 10.1161/CIRCRESAHA.122.322223

PMCID:: PMC10284140

Abstract Article PDF–26M

Select item 1015436112.

Generation of new transgenic SMARCA4‐deficient mouse models results in neuromuscular weakness and paralysis of limbs

Sina Neyazi, Lea Altendorf, Dora Schwetje, Carolin Göbel, Melanie Schoof, Dörthe Holdhof, Ulrich Schüller

Brain Pathol. 2023 May; 33(3): e13146. Published online 2022 Dec 29. doi: 10.1111/bpa.13146

PMCID:: PMC10154361

Article PDF–346K

Select item 1002740213.

Divergent transcriptional regulation of astrocyte reactivity across disorders

Joshua E. Burda, Timothy M. O’Shea, Yan Ao, Keshav B. Suresh, Shinong Wang, Alexander M. Bernstein, Ashu Chandra, Sandeep Deverasetty, Riki Kawaguchi, Jae H. Kim, Sarah McCallum, Alexandra Rogers, Shalaka Wahane, Michael V. Sofroniew

Nature. Author manuscript; available in PMC 2023 Mar 20.

Published in final edited form as: Nature. 2022 Jun; 606(7914): 557–564. Published online 2022 May 25. doi: 10.1038/s41586-022-04739-5

Correction in:: Nature. 2023 Mar 28

PMCID:: PMC10027402

Abstract Article PDF–5.9M

Select item 993040014.

SWI/SNF chromatin remodeling subunit Smarca4/BRG1 is essential for female fertility

Atefeh Abedini, David A Landry, Angus D Macaulay, Het Vaishnav, Ashna Parbhakar, Dalia Ibrahim, Reza Salehi, Vincent Maranda, Elizabeth Macdonald, Barbara C Vanderhyden

Biol Reprod. 2023 Feb; 108(2): 279–291. Published online 2022 Nov 28. doi: 10.1093/biolre/ioac209

Correction in:: Biol Reprod. 2023 Apr; 108(4): 708.

PMCID:: PMC9930400

Abstract Article PDF–1.9M

Select item 991168715.

Suppression of microRNA-222-3p ameliorates ulcerative colitis and colitis-associated colorectal cancer to protect against oxidative stress via targeting BRG1 to activate Nrf2/HO-1 signaling pathway

Xue-jun Wang, Dan Zhang, Yan-ting Yang, Xiao-ying Li, Hong-na Li, Xiao-peng Zhang, Jun-yi Long, Yun-qiong Lu, Li Liu, Guang Yang, Jie Liu, Jue Hong, Huan-gan Wu, Xiao-peng Ma

Front Immunol. 2023; 14: 1089809. Published online 2023 Jan 27. doi: 10.3389/fimmu.2023.1089809

PMCID:: PMC9911687

Abstract Article PDF–9.1M

Select item 963715816.

The assembly of mammalian SWI/SNF chromatin remodeling complexes is regulated by lysine-methylation dependent proteolysis

Pengfei Guo, Nam Hoang, Joseph Sanchez, Elaine H. Zhang, Keshari Rajawasam, Kristiana Trinidad, Hong Sun, Hui Zhang

Nat Commun. 2022; 13: 6696. Published online 2022 Nov 5. doi: 10.1038/s41467-022-34348-9

PMCID:: PMC9637158

Abstract Article PDF–3.3M

Select item 960625317.

Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome

Sasha L. Fulton, Wendy Wenderski, Ashley E. Lepack, Andrew L. Eagle, Tomas Fanutza, Ryan M. Bastle, Aarthi Ramakrishnan, Emma C. Hays, Arianna Neal, Jaroslav Bendl, Lorna A. Farrelly, Amni Al-Kachak, Yang Lyu, Bulent Cetin, Jennifer C. Chan, Tina N. Tran, Rachael L. Neve, Randall J. Roper, Kristen J. Brennand, Panos Roussos, John C. Schimenti, Allyson K. Friedman, Li Shen, Robert D. Blitzer, Alfred J. Robison, Gerald R. Crabtree, Ian Maze

Nat Commun. 2022; 13: 6384. Published online 2022 Oct 26. doi: 10.1038/s41467-022-34200-0

PMCID:: PMC9606253

Abstract Article PDF–4.0M

Select item 953085718.

JNK pathway plays a critical role for expansion of human colorectal cancer in the context of BRG1 suppression

Takaaki Yoshikawa, Akihisa Fukuda, Mayuki Omatsu, Mio Namikawa, Makoto Sono, Yuichi Fukunaga, Tomonori Masuda, Osamu Araki, Munemasa Nagao, Satoshi Ogawa, Kenji Masuo, Norihiro Goto, Yukiko Hiramatsu, Yu Muta, Motoyuki Tsuda, Takahisa Maruno, Yuki Nakanishi, Kenji Kawada, Shigeo Takaishi, Hiroshi Seno

Cancer Sci. 2022 Oct; 113(10): 3417–3427. Published online 2022 Aug 17. doi: 10.1111/cas.15520

PMCID:: PMC9530857

Abstract Article PDF–32M

Select item 920370419.

Hemogen/BRG1 cooperativity modulates promoter and enhancer activation during erythropoiesis

Xiang Guo, Yangu Zhao, Juhyun Kim, Ann Dean

Blood. 2022 Jun 16; 139(24): 3532–3545. doi: 10.1182/blood.2021014308

PMCID:: PMC9203704

Abstract Article

Select item 919699320.

Brahma safeguards canalization of cardiac mesoderm differentiation

Swetansu K. Hota, Kavitha S. Rao, Andrew P. Blair, Ali Khalilimeybodi, Kevin M. Hu, Reuben Thomas, Kevin So, Vasumathi Kameswaran, Jiewei Xu, Benjamin J. Polacco, Ravi V. Desai, Nilanjana Chatterjee, Austin Hsu, Jonathon M. Muncie, Aaron M. Blotnick, Sarah A.B. Winchester, Leor S. Weinberger, Ruth Hüttenhain, Irfan S. Kathiriya, Nevan J. Krogan, Jeffrey J. Saucerman, Benoit G. Bruneau

Nature. Author manuscript; available in PMC 2022 Jun 14.

Published in final edited form as: Nature. 2022 Feb; 602(7895): 129–134. Published online 2022 Jan 26. doi: 10.1038/s41586-021-04336-y

PMCID:: PMC9196993

Abstract Article PDF–5.8M

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