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Select item 111025181.

Macrophages communicate with mesangial cells through the CXCL12/DPP4 axis in lupus nephritis pathogenesis

Weiwei Li, Chun Yao, Haixia Guo, Xi’an Ni, Ran Zhu, Yongjun Wang, Bin Yu, Xuebing Feng, Zhifeng Gu, Zhanyun Da

Cell Death Dis. 2024 May; 15(5): 344. Published online 2024 May 18. doi: 10.1038/s41419-024-06708-4

PMCID:: PMC11102518

Abstract Article PDF–6.7M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107462243.

Contrasting roles of MERS-CoV and SARS-CoV-2 internal proteins in pathogenesis in mice

Lok-Yin Roy Wong, Abby Odle, Emma Luhmann, Douglas C. Wu, Yiquan Wang, Qi Wen Teo, Celeste Ptak, Alan Sariol, Shea Lowery, Matthias Mack, David K. Meyerholz, Nicholas C. Wu, Lilliana Radoshevich, Stanley Perlman

mBio. 2023 Nov-Dec; 14(6): e02476-23. Published online 2023 Oct 26. doi: 10.1128/mbio.02476-23

PMCID:: PMC10746224

Abstract Article PDF–909K

Select item 106713394.

Dipeptidyl Peptidase 4 Stimulation Induces Adipogenesis-Related Gene Expression of Adipose Stromal Cells

Hsiao-Chi Lai, Pei-Hsuan Chen, Chia-Hua Tang, Lee-Wei Chen

Int J Mol Sci. 2023 Nov; 24(22): 16101. Published online 2023 Nov 8. doi: 10.3390/ijms242216101

PMCID:: PMC10671339

Abstract Article PDF–3.7M

Select item 104325775.

Dipeptidylpeptidase 4 promotes survival and stemness of acute myeloid leukemia stem cells

Chen Wang, Ravi Nistala, Min Cao, Yi Pan, Madelaine Behrens, Donald Doll, Richard D. Hammer, Puja Nistala, Hui-Ming Chang, Edward T.H. Yeh, XunLei Kang

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Feb 28; 42(2): 112105. Published online 2023 Feb 17. doi: 10.1016/j.celrep.2023.112105

PMCID:: PMC10432577

Abstract Article PDF–2.5M

Select item 101929266.

Pancreas-derived DPP4 is not essential for glucose homeostasis under metabolic stress

Evgenia Fadzeyeva, Cassandra A.A. Locatelli, Natasha A. Trzaskalski, My-Anh Nguyen, Megan E. Capozzi, Branka Vulesevic, Nadya M. Morrow, Peyman Ghorbani, Antonio A. Hanson, Ilka Lorenzen-Schmidt, Mary-Anne Doyle, Richard Seymour, Elodie M. Varin, Morgan D. Fullerton, Jonathan E. Campbell, Erin E. Mulvihill

iScience. 2023 May 19; 26(5): 106748. Published online 2023 Apr 26. doi: 10.1016/j.isci.2023.106748

PMCID:: PMC10192926

Abstract Article PDF–5.4M

Select item 100379657.

Dipeptidyl Peptidase 4/Midline‐1 Axis Promotes T Lymphocyte Motility in Atherosclerosis

Xiaoquan Rao, Michael Razavi, Georgeta Mihai, Yingying Wei, Zachary Braunstein, Matthew B. Frieman, Xiao Jian Sun, Quan Gong, Jun Chen, Gang Zhao, Zheng Liu, Michael J. Quon, Lingli Dong, Sanjay Rajagopalan, Jixin Zhong

Adv Sci (Weinh) 2023 Mar; 10(9): 2204194. Published online 2023 Jan 22. doi: 10.1002/advs.202204194

PMCID:: PMC10037965

Abstract Article PDF–9.7M

Select item 100340078.

Functional roles of CD26/DPP4 in bleomycin‐induced pulmonary fibrosis

Yu Koyanagi, Takeshi Kawasaki, Yoshitoshi Kasuya, Ryo Hatano, Shun Sato, Yukiko Takahashi, Kei Ohnuma, Chikao Morimoto, Steven M. Dudek, Koichiro Tatsumi, Takuji Suzuki

Physiol Rep. 2023 Mar; 11(6): e15645. Published online 2023 Mar 22. doi: 10.14814/phy2.15645

PMCID:: PMC10034007

Abstract Article PDF–21M

Select item 100142739.

Non-canonical function of DPP4 promotes cognitive impairment through ERp29-associated mitochondrial calcium overload in diabetes

Jiaxiu Li, Ya Hui, Zhiqiang Xu, Jie Tan, Kai Yin, Liuyu Kuang, Yunyun Tang, Junjie Wei, Qiongsui Zhong, Tianpeng Zheng

iScience. 2023 Mar 17; 26(3): 106271. Published online 2023 Feb 27. doi: 10.1016/j.isci.2023.106271

PMCID:: PMC10014273

Abstract Article PDF–8.6M

Select item 997731410.

Hepatocyte-derived DPP4 regulates portal GLP-1 bioactivity, modulates glucose production, and when absent influences NAFLD progression

Natasha A. Trzaskalski, Branka Vulesevic, My-Anh Nguyen, Natasha Jeraj, Evgenia Fadzeyeva, Nadya M. Morrow, Cassandra A.A. Locatelli, Nicole Travis, Antonio A. Hanson, Julia R.C. Nunes, Conor O’Dwyer, Jelske N. van der Veen, Ilka Lorenzen-Schmidt, Rick Seymour, Serena M. Pulente, Andrew C. Clément, Angela M. Crawley, René L. Jacobs, Mary-Anne Doyle, Curtis L. Cooper, Kyoung-Han Kim, Morgan D. Fullerton, Erin E. Mulvihill

JCI Insight. 2023 Jan 24; 8(2): e154314. Published online 2023 Jan 24. doi: 10.1172/jci.insight.154314

PMCID:: PMC9977314

Abstract Article PDF–30M

Select item 986997911.

SARS-CoV-2 infection of sustentacular cells disrupts olfactory signaling pathways

Abhishek Kumar Verma, Jian Zheng, David K. Meyerholz, Stanley Perlman

JCI Insight. 2022 Dec 22; 7(24): e160277. Published online 2022 Dec 22. doi: 10.1172/jci.insight.160277

PMCID:: PMC9869979

Abstract Article PDF–6.5M

Select item 930883912.

Dipeptidyl peptidase IV inhibition delays developmental programming of obesity and metabolic disease in male offspring of obese mothers

Kim Ramil C. Montaniel, Matthew Bucher, Elysse A. Phillips, Cun Li, Elinor L. Sullivan, Paul Kievit, Sandra Rugonyi, Peter W. Nathanielsz, Alina Maloyan

J Dev Orig Health Dis. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: J Dev Orig Health Dis. 2022 Dec; 13(6): 727–740. Published online 2022 Jan 24. doi: 10.1017/S2040174422000010

PMCID:: PMC9308839

Abstract Article PDF–2.8M

Select item 919984713.

Leukemia Inhibitory Factor Promotes Survival of Hematopoietic Progenitors Ex Vivo and Is Post-Translationally Regulated by DPP4

James Ropa, Scott Cooper, Hal E Broxmeyer

Stem Cells. 2022 Mar; 40(3): 346–357. Published online 2022 Jan 28. doi: 10.1093/stmcls/sxac004

PMCID:: PMC9199847

Abstract Article PDF–7.5M

Select item 914185614.

CD26 Deficiency Controls Macrophage Polarization Markers and Signal Transducers during Colitis Development and Resolution

Iva Vukelic, Suncica Buljevic, Lara Baticic, Karmela Barisic, Barbara Franovic, Dijana Detel

Int J Mol Sci. 2022 May; 23(10): 5506. Published online 2022 May 14. doi: 10.3390/ijms23105506

PMCID:: PMC9141856

Abstract Article PDF–5.4M

Select item 912025915.

Skin fibrosis and recovery is dependent on Wnt activation via DPP4

Anna R. Jussila, Brian Zhang, Elizabeth Caves, Sakin Kirti, Miarasa Steele, Emily Hamburg-Shields, John Lydon, Yan Ying, Robert Lafyatis, Sanjay Rajagopalan, Valerie Horsley, Radhika P. Atit

J Invest Dermatol. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: J Invest Dermatol. 2022 Jun; 142(6): 1597–1606.e9. Published online 2021 Nov 20. doi: 10.1016/j.jid.2021.10.025

PMCID:: PMC9120259

Abstract Article PDF–2.3M

Select item 901662016.

Vertebrate lonesome kinase modulates the hepatocyte secretome to prevent perivascular liver fibrosis and inflammation

Sophia Pantasis, Juliane Friemel, Salome Mirjam Brütsch, Zehan Hu, Sabrina Krautbauer, Gerhard Liebisch, Joern Dengjel, Achim Weber, Sabine Werner, Mattia Renato Bordoli

J Cell Sci. 2022 Apr 1; 135(7): jcs259243. Published online 2022 Apr 12. doi: 10.1242/jcs.259243

PMCID:: PMC9016620

Abstract Article

Select item 896064017.

Prediabetes blunts DPP4 genetic control of postprandial glycaemia and insulin secretion

Rita S. Patarrão, Nádia Duarte, Inês Coelho, Joey Ward, Rogério T. Ribeiro, Maria João Meneses, Rita Andrade, João Costa, Isabel Correia, José Manuel Boavida, Rui Duarte, Luís Gardete-Correia, José Luís Medina, Jill Pell, John Petrie, João F. Raposo, Maria Paula Macedo, Carlos Penha-Gonçalves

Diabetologia. 2022; 65(5): 861–871. Published online 2022 Feb 22. doi: 10.1007/s00125-021-05638-6

PMCID:: PMC8960640

Abstract Article PDF–1.4M

Select item 863935918.

Middle East respiratory syndrome coronavirus vaccine based on a propagation-defective RNA replicon elicited sterilizing immunity in mice

J. Gutiérrez-Álvarez, J. M. Honrubia, A. Sanz-Bravo, E. González-Miranda, R. Fernández-Delgado, M. T. Rejas, S. Zúñiga, I. Sola, L. Enjuanes

Proc Natl Acad Sci U S A. 2021 Oct 26; 118(43): e2111075118. Published online 2021 Oct 22. doi: 10.1073/pnas.2111075118

PMCID:: PMC8639359

Abstract Article PDF–2.1M

Select item 861400919.

Dipeptidyl peptidase-4 inhibition prevents lung injury in mice under chronic stress via the modulation of oxidative stress and inflammation

Shengming Zhang, Ping Li, Minglong Xin, Xianglan Jin, Longguo Zhao, Yongshan Nan, Xian Wu Cheng

Exp Anim. 2021; 70(4): 541–552. Published online 2021 Jul 5. doi: 10.1538/expanim.21-0067

PMCID:: PMC8614009

Abstract Article PDF–2.3M

Select item 858137020.

Dpp4+ interstitial progenitor cells contribute to basal and high fat diet-induced adipogenesis

Megan Stefkovich, Sarah Traynor, Lan Cheng, David Merrick, Patrick Seale

Mol Metab. 2021 Dec; 54: 101357. Published online 2021 Oct 15. doi: 10.1016/j.molmet.2021.101357

PMCID:: PMC8581370

Abstract Article PDF–6.9M

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