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Select item 110646661.

Loss of Grp170 results in catastrophic disruption of endoplasmic reticulum function

Melissa J. Mann, Chris Melendez-Suchi, Hannah E. Vorndran, Maria Sukhoplyasova, Ashley R. Flory, Mary Carson Irvine, Anuradha R. Iyer, Christopher J. Guerriero, Jeffrey L. Brodsky, Linda M. Hendershot, Teresa M. Buck

Mol Biol Cell. 2024 Apr 1; 35(4): ar59. Published online 2024 Mar 21. doi: 10.1091/mbc.E24-01-0012

PMCID:: PMC11064666

Abstract Article PDF–1.7M

Select item 103078522.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 99232273.

FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response

Zhe Wang, Chen Tan, Caihan Duan, Junhao Wu, Dan Zhou, Lingzhi Hou, Wei Qian, Chaoqun Han, Xiaohua Hou

Redox Biol. 2023 Apr; 60: 102618. Published online 2023 Jan 28. doi: 10.1016/j.redox.2023.102618

PMCID:: PMC9923227

Abstract Article PDF–17M

Select item 97469164.

HIF1 inhibitor acriflavine rescues early-onset preeclampsia phenotype in mice lacking placental prolyl hydroxylase domain protein 2

Julien Sallais, Chanho Park, Sruthi Alahari, Tyler Porter, Ruizhe Liu, Merve Kurt, Abby Farrell, Martin Post, Isabella Caniggia

JCI Insight. 2022 Dec 8; 7(23): e158908. Published online 2022 Dec 8. doi: 10.1172/jci.insight.158908

PMCID:: PMC9746916

Abstract Article PDF–7.1M

Select item 89831415.

The molecular chaperone GRP170 protects against ER stress and acute kidney injury in mice

Aidan W. Porter, Diep N. Nguyen, Dennis R. Clayton, Wily G. Ruiz, Stephanie M. Mutchler, Evan C. Ray, Allison L. Marciszyn, Lubika J. Nkashama, Arohan R. Subramanya, Sebastien Gingras, Thomas R. Kleyman, Gerard Apodaca, Linda M. Hendershot, Jeffrey L. Brodsky, Teresa M. Buck

JCI Insight. 2022 Mar 8; 7(5): e151869. Published online 2022 Mar 8. doi: 10.1172/jci.insight.151869

PMCID:: PMC8983141

Abstract Article PDF–22M

Select item 83132396.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78518678.

Coordination of Grp1 recruitment mechanisms by its phosphorylation

Jian Li, David G. Lambright, Victor W. Hsu

Mol Biol Cell. 2020 Dec 1; 31(25): 2816–2825. doi: 10.1091/mbc.E20-03-0173

PMCID:: PMC7851867

Abstract Article PDF–1.3M

Select item 67303259.

ORP150/HSP12A Regulates Purkinje Cell Survival: A Role for Endoplasmic Reticulum Stress in Cerebellar Development

Yasuko Kitao, Kouichi Hashimoto, Tomohiro Matsuyama, Hiroyuki Iso, Takeshi Tamatani, Osamu Hori, David M. Stern, Masanobu Kano, Kentaro Ozawa, Satoshi Ogawa

J Neurosci. 2004 Feb 11; 24(6): 1486–1496. doi: 10.1523/JNEUROSCI.4029-03.2004

PMCID:: PMC6730325

Abstract Article PDF–1.1M

Select item 665555110.

WDFY4 is required for cross-presentation in response to viral and tumor antigens

Derek J. Theisen, Jesse T. Davidson, IV, Carlos G. Briseño, Marco Gargaro, Elvin J. Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R. Brickner, Wandy L. Beatty, Herbert W. Virgin, William E. Gillanders, Nima Mosammaparast, Michael S. Diamond, L. David Sibley, Wayne Yokoyama, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy

Science. Author manuscript; available in PMC 2019 Jul 24.

Published in final edited form as: Science. 2018 Nov 9; 362(6415): 694–699. doi: 10.1126/science.aat5030

PMCID:: PMC6655551

Abstract Article PDF–1020K

Select item 629804011.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 624418312.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 538122613.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 474776814.

The LMO2 oncogene regulates DNA replication in hematopoietic cells

Marie-Claude Sincennes, Magali Humbert, Benoît Grondin, Véronique Lisi, Diogo F. T. Veiga, André Haman, Christophe Cazaux, Nazar Mashtalir, EL Bachir Affar, Alain Verreault, Trang Hoang

Proc Natl Acad Sci U S A. 2016 Feb 2; 113(5): 1393–1398. Published online 2016 Jan 13. doi: 10.1073/pnas.1515071113

PMCID:: PMC4747768

Abstract Article PDF–1.0M

Select item 407349415.

The Central Role of EED in the Orchestration of Polycomb Group Complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Nat Commun. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127

PMCID:: PMC4073494

Abstract Article PDF–2.1M

Select item 390842216.

The Large Hsp70 Grp170 Binds to Unfolded Protein Substrates in Vivo with a Regulation Distinct from Conventional Hsp70s

Julia Behnke, Linda M. Hendershot

J Biol Chem. 2014 Jan 31; 289(5): 2899–2907. Published online 2013 Dec 10. doi: 10.1074/jbc.M113.507491

PMCID:: PMC3908422

Abstract Article PDF–3.9M

Select item 385838517.

Enhanced ER entry of tumor antigen is crucial for cross-presentation induced by dendritic cell-targeted vaccination

Hongxia Wang, Xiaofei Yu, Chunqing Guo, Daming Zuo, Paul B. Fisher, John R. Subjeck, Xiang-Yang Wang

J Immunol. Author manuscript; available in PMC 2014 Dec 15.

Published in final edited form as: J Immunol. 2013 Dec 15; 191(12): 10.4049/jimmunol.1302312. Published online 2013 Nov 11. doi: 10.4049/jimmunol.1302312

PMCID:: PMC3858385

Abstract Article PDF–3.1M

Select item 331690718.

Molecular chaperoning by glucose-regulated protein 170 in the extracellular milieu promotes macrophage-mediated pathogen sensing and innate immunity

Daming Zuo, Xiaofei Yu, Chunqing Guo, Huanfa Yi, Xing Chen, Daniel H. Conrad, Tai L. Guo, Zhengliang Chen, Paul B. Fisher, John R. Subjeck, Xiang-Yang Wang

FASEB J. 2012 Apr; 26(4): 1493–1505. doi: 10.1096/fj.11-197707

PMCID:: PMC3316907

Abstract Article

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 309102620.

Tumor secreted grp170 chaperones full-length protein substrates and induces an adaptive anti-tumor immune response in vivo

Hilal Arnouk, Evan R. Zynda, Xiang-Yang Wang, Bonnie L. Hylander, Masoud H. Manjili, Elizabeth A. Repasky, John R. Subjeck, A. Latif Kazim

Int J Hyperthermia. Author manuscript; available in PMC 2011 May 10.

Published in final edited form as: Int J Hyperthermia. 2010; 26(4): 366–375. doi: 10.3109/02656730903485910

PMCID:: PMC3091026

Abstract Article PDF–1.5M

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