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Items: 1 to 20 of 117

1.
T-follicular regulatory cells expand to control germinal center plasma cell output but fail to curb autoreactivity
Cecilia Fahlquist-Hagert, Thomas Rea Wittenborn, Mattias Krogh Pedersen, Lisbeth Jensen, Søren Egedal Degn
iScience. 2024 Oct 18; 27(10): 110887. Published online 2024 Sep 4. doi: 10.1016/j.isci.2024.110887
PMCID:
PMC11417334
AbstractArticlePDF–6.6M
2.
T cell help shapes B cell tolerance
Elliot H. Akama-Garren, Xihui Yin, Tyler R. Prestwood, Minghe Ma, Paul J. Utz, Michael C. Carroll
Sci Immunol. Author manuscript; available in PMC 2024 May 15.
Published in final edited form as: Sci Immunol. 2024 Feb 16; 9(92): eadj7029. Published online 2024 Feb 16. doi: 10.1126/sciimmunol.adj7029
PMCID:
PMC11095409
AbstractArticlePDF–4.5M
3.
B cell MHC haplotype affects follicular inclusion, germinal center participation and plasma cell differentiation in a mouse model of lupus
Camilla Wibrand, Thomas R. Wittenborn, Lasse Frank Voss, Gudrun Winther, Lisbeth Jensen, Alexey Ferapontov, Sofie V. Fonager, Cecilia Fahlquist-Hagert, Søren E. Degn
Front Immunol. 2023; 14: 1258046. Published online 2023 Nov 28. doi: 10.3389/fimmu.2023.1258046
PMCID:
PMC10715410
AbstractArticlePDF–5.6M
4.
Antigen presentation by B cells enables epitope spreading across an MHC barrier
Cecilia Fahlquist-Hagert, Thomas R. Wittenborn, Ewa Terczyńska-Dyla, Kristian Savstrup Kastberg, Emily Yang, Alysa Nicole Rallistan, Quinton Raymond Markett, Gudrun Winther, Sofie Fonager, Lasse F. Voss, Mathias K. Pedersen, Nina van Campen, Alexey Ferapontov, Lisbeth Jensen, Jinrong Huang, John D. Nieland, Cees E. van der Poel, Johan Palmfeldt, Michael C. Carroll, Paul J. Utz, Yonglun Luo, Lin Lin, Søren E. Degn
Nat Commun. 2023; 14: 6941. Published online 2023 Oct 31. doi: 10.1038/s41467-023-42541-7
PMCID:
PMC10618542
AbstractArticlePDF–6.2M
5.
Complex subsets but redundant clonality after B cells egress from spontaneous germinal centers
Carlos Castrillon, Lea Simoni, Theo van den Broek, Cees van der Poel, Elliot H Akama-Garren, Minghe Ma, Michael C Carroll
eLife. 2023; 12: e81012. Published online 2023 Jun 21. doi: 10.7554/eLife.81012
PMCID:
PMC10351918
AbstractArticlePDF–3.1M
6.
Molecular fate-mapping of serum antibody responses to repeat immunization
Ariën Schiepers, Marije F. L. van ‘t Wout, Allison J. Greaney, Trinity Zang, Hiromi Muramatsu, Paulo J. C. Lin, Ying K. Tam, Luka Mesin, Tyler N. Starr, Paul D. Bieniasz, Norbert Pardi, Jesse D. Bloom, Gabriel D. Victora
Nature. Author manuscript; available in PMC 2023 Sep 1.
Published in final edited form as: Nature. 2023 Mar; 615(7952): 482–489. Published online 2023 Jan 16. doi: 10.1038/s41586-023-05715-3
PMCID:
PMC10023323
AbstractArticlePDF–2.7M
7.
The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus
Lasse F. Voss, Amanda J. Howarth, Thomas R. Wittenborn, Sandra Hummelgaard, Kristian Juul-Madsen, Kristian S. Kastberg, Mathias K. Pedersen, Lisbeth Jensen, Anastasios D. Papanastasiou, Thomas Vorup-Jensen, Kathrin Weyer, Søren E. Degn
Front Immunol. 2022; 13: 1021370. Published online 2022 Dec 14. doi: 10.3389/fimmu.2022.1021370
PMCID:
PMC9795406
AbstractArticlePDF–9.8M
8.
Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift
Yang Zhang, Laura Garcia-Ibanez, Carolin Ulbricht, Laurence S. C. Lok, Jeremy A. Pike, Jennifer Mueller-Winkler, Thomas W. Dennison, John R. Ferdinand, Cameron J. M. Burnett, Juan C. Yam-Puc, Lingling Zhang, Raul Maqueda Alfaro, Yousuke Takahama, Izumi Ohigashi, Geoffrey Brown, Tomohiro Kurosaki, Victor L. J. Tybulewicz, Antal Rot, Anja E. Hauser, Menna R. Clatworthy, Kai-Michael Toellner
Nat Commun. 2022; 13: 2460. Published online 2022 May 5. doi: 10.1038/s41467-022-29978-y
PMCID:
PMC9072412
AbstractArticlePDF–8.3M
9.
Highly mutated antibodies capable of neutralizing N276 glycan-deficient HIV after a single immunization with an Env trimer
Jeong Hyun Lee, Catherine Nakao, Michael Appel, Amber Le, Elise Landais, Oleksandr Kalyuzhniy, Xiaozhen Hu, Alessia Liguori, Tina-Marie Mullen, Bettina Groschel, Robert K. Abbott, Devin Sok, William R. Schief, Shane Crotty
Cell Rep. 2022 Mar 8; 38(10): 110485. Published online 2022 Mar 8. doi: 10.1016/j.celrep.2022.110485
PMCID:
PMC8924373
AbstractArticlePDF–4.0M
10.
B Cell Intrinsic STING Signaling Is Not Required for Autoreactive Germinal Center Participation
Kenneth Green, Thomas R. Wittenborn, Cecilia Fahlquist-Hagert, Ewa Terczynska-Dyla, Nina van Campen, Lisbeth Jensen, Line Reinert, Rune Hartmann, Søren R. Paludan, Søren E. Degn
Front Immunol. 2021; 12: 782558. Published online 2021 Dec 6. doi: 10.3389/fimmu.2021.782558
PMCID:
PMC8685402
AbstractArticlePDF–11M
11.
Protein kinase Cδ is essential for the IgG response against T-cell-independent type 2 antigens and commensal bacteria
Saori Fukao, Kei Haniuda, Hiromasa Tamaki, Daisuke Kitamura
eLife. 2021; 10: e72116. Published online 2021 Oct 25. doi: 10.7554/eLife.72116
PMCID:
PMC8610492
AbstractArticlePDF–1.4M
12.
Follicular dendritic cell activation by TLR ligands promotes autoreactive B cell responses
Abhishek Das, Balthasar A. Heesters, Allison Bialas, Joseph O’Flynn, Ian R. Rifkin, Jordi Ochando, Nanette Mittereder, Gianluca Carlesso, Ronald Herbst, Michael C. Carroll
Immunity. Author manuscript; available in PMC 2021 May 22.
Published in final edited form as: Immunity. 2017 Jan 17; 46(1): 106–119. doi: 10.1016/j.immuni.2016.12.014
PMCID:
PMC8140609
AbstractArticlePDF–1.0M
13.
Complement C4A Regulates Autoreactive B Cells in Murine Lupus
Léa Simoni, Jessy Presumey, Cees E. van der Poel, Carlos Castrillon, Sarah E. Chang, Paul J. Utz, Michael C. Carroll
Cell Rep. Author manuscript; available in PMC 2021 Mar 3.
Published in final edited form as: Cell Rep. 2020 Nov 3; 33(5): 108330. doi: 10.1016/j.celrep.2020.108330
PMCID:
PMC7927756
AbstractArticlePDF–2.4M
14.
IgH 3’ regulatory region increases ectopic class switch recombination
Sandrine Le Noir, Amélie Bonaud, Bastien Hervé, Audrey Baylet, François Boyer, Sandrine Lecardeur, Zeliha Oruc, Christophe Sirac, Michel Cogné
PLoS Genet. 2021 Feb; 17(2): e1009288. Published online 2021 Feb 8. doi: 10.1371/journal.pgen.1009288
PMCID:
PMC7869978
AbstractArticlePDF–1.9M
15.
Hepatocyte-Derived Igκ Exerts a Protective Effect against ConA-Induced Acute Liver Injury
Sha Yin, Qianwen Shi, Wenwei Shao, Chi Zhang, Yixiao Zhang, Xiaoyan Qiu, Jing Huang
Int J Mol Sci. 2020 Dec; 21(24): 9379. Published online 2020 Dec 9. doi: 10.3390/ijms21249379
PMCID:
PMC7763521
AbstractArticlePDF–3.5M
16.
ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells
Xiaojing Liu, Tingting Liu, Yafang Shang, Pengfei Dai, Wubing Zhang, Brian J. Lee, Min Huang, Dingpeng Yang, Qiu Wu, Liu Daisy Liu, Xiaoqi Zheng, Bo O. Zhou, Junchao Dong, Leng-Siew Yeap, Jiazhi Hu, Tengfei Xiao, Shan Zha, Rafael Casellas, X. Shirley Liu, Fei-Long Meng
Cell Res. 2020 Sep; 30(9): 732–744. Published online 2020 Apr 30. doi: 10.1038/s41422-020-0328-3
PMCID:
PMC7608219
AbstractArticlePDF–4.1M
17.
Multifaceted Effects of Antigen Valency on B Cell Response Composition and Differentiation In Vivo
Yu Kato, Robert K. Abbott, Brian L. Freeman, Sonya Haupt, Bettina Groschel, Murillo Silva, Sergey Menis, Darrell J. Irvine, William R. Schief, Shane Crotty
Immunity. 2020 Sep 15; 53(3): 548–563.e8. Published online 2020 Aug 27. doi: 10.1016/j.immuni.2020.08.001
PMCID:
PMC7451196
AbstractArticlePDF–6.5M
18.
MouseVk gene classification by nucleic acid sequence similarity
Robert Strohal, Arno Helmberg, Guido Kroemer, Reinhard Kofler
Immunogenetics. 1989; 30(6): 475–493. doi: 10.1007/BF02421180
PMCID:
PMC7087523
AbstractArticlePDF–1.9M
19.
IL-12 Blocks Tfh Cell Differentiation during Salmonella Infection, thereby Contributing to Germinal Center Suppression
Rebecca A. Elsner, Mark J. Shlomchik
Cell Rep. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell Rep. 2019 Nov 26; 29(9): 2796–2809.e5. doi: 10.1016/j.celrep.2019.10.069
PMCID:
PMC6908568
AbstractArticlePDF–2.1M
20.
The quantity of CD40 signaling determines the differentiation of B cells into functionally distinct memory cell subsets
Takuya Koike, Koshi Harada, Shu Horiuchi, Daisuke Kitamura
eLife. 2019; 8: e44245. Published online 2019 Jun 21. doi: 10.7554/eLife.44245
PMCID:
PMC6636905
AbstractArticlePDF–4.2M

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