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Select item 112451531.

Loss-of-function mutations of the TIE1 receptor tyrosine kinase cause late-onset primary lymphedema

Pascal Brouillard, Aino Murtomäki, Veli-Matti Leppänen, Marko Hyytiäinen, Sandrine Mestre, Lucas Potier, Laurence M. Boon, Nicole Revencu, Arin Greene, Andrey Anisimov, Miia H. Salo, Reetta Hinttala, Lauri Eklund, Isabelle Quéré, Kari Alitalo, Miikka Vikkula

J Clin Invest. 2024 Jul 15; 134(14): e173586. Published online 2024 May 30. doi: 10.1172/JCI173586

PMCID:: PMC11245153

Abstract Article PDF–2.9M

Select item 109811582.

Primary Cilium in Neural Crest Cells Crucial for Anterior Segment Development and Corneal Avascularity

Seungwoon Seo, Seong Keun Sonn, Hyae Yon Kweon, Jing Jin, Tsutomu Kume, Je Yeong Ko, Jong Hoon Park, Goo Taeg Oh

Invest Ophthalmol Vis Sci. 2024 Mar; 65(3): 30. Published online 2024 Mar 22. doi: 10.1167/iovs.65.3.30

PMCID:: PMC10981158

Abstract Article PDF–20M

Select item 108146853.

PKD1L1 Is Involved in Congenital Chylothorax

Jonathan B. Whitchurch, Sophia Schneider, Alina C. Hilger, Ricarda Köllges, Jil D. Stegmann, Lea Waffenschmidt, Laura Dyer, Holger Thiele, Bhanupriya Dhabhai, Tikam Chand Dakal, Andreas Müller, Dominic P. Norris, Heiko M. Reutter

Cells. 2024 Jan; 13(2): 149. Published online 2024 Jan 12. doi: 10.3390/cells13020149

PMCID:: PMC10814685

Abstract Article PDF–13M

Select item 107512444.

VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis

Miguel Sáinz-Jaspeado, Sarah Ring, Steven T Proulx, Mark Richards, Pernilla Martinsson, Xiujuan Li, Lena Claesson-Welsh, Maria H Ulvmar, Yi Jin

Life Sci Alliance. 2024 Mar; 7(3): e202302168. Published online 2023 Dec 26. doi: 10.26508/lsa.202302168

PMCID:: PMC10751244

Abstract Article PDF–4.5M

Select item 107027845.

Ontogenesis of the Mouse Ocular Surface Lymphatic Vascular Network

Mariela Subileau, Daniel Vittet

Invest Ophthalmol Vis Sci. 2023 Dec; 64(15): 7. Published online 2023 Dec 6. doi: 10.1167/iovs.64.15.7

PMCID:: PMC10702784

Abstract Article PDF–12M

Select item 106296796.

Endothelial cell SMAD6 balances Alk1 function to regulate adherens junctions and hepatic vascular development

Molly R. Kulikauskas, Morgan Oatley, Tianji Yu, Ziqing Liu, Lauren Matsumura, Elise Kidder, Dana Ruter, Victoria L. Bautch

Development. 2023 Nov 1; 150(21): dev201811. Published online 2023 Nov 3. doi: 10.1242/dev.201811

PMCID:: PMC10629679

Abstract Article

Select item 105711597.

Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function

Lorenzo M. Fernandes, Jeffrey Tresemer, Jing Zhang, Jonathan J. Rios, Joshua P. Scallan, Michael T. Dellinger

Front Cell Dev Biol. 2023; 11: 1276333. Published online 2023 Sep 25. doi: 10.3389/fcell.2023.1276333

PMCID:: PMC10571159

Abstract Article PDF–14M

Select item 105601148.

hsa_circ_0129047 Upregulates LYVE1 to Inhibit Hepatocellular Carcinoma Progression by Sponging miR-492

Zhenzhen Feng, Jiyuan Wu

Dis Markers. 2023; 2023: 6978234. Published online 2023 Sep 30. doi: 10.1155/2023/6978234

PMCID:: PMC10560114

Abstract Article PDF–1.6M

Select item 102811859.

CD47 Activation by Thrombospondin-1 in Lymphatic Endothelial Cells Suppresses Lymphangiogenesis and Promotes Atherosclerosis

Bhupesh Singla, Ravi Varma Aithbathula, Naveed Pervaiz, Ishita Kathuria, Mallory Swanson, Frederick Adams Ekuban, WonMo Ahn, Frank Park, Maxwell Gyamfi, Mary Cherian-Shaw, Udai P. Singh, Santosh Kumar

Arterioscler Thromb Vasc Biol. 2023 Jul; 43(7): 1234–1250. Published online 2023 Jun 1. doi: 10.1161/ATVBAHA.122.318904

PMCID:: PMC10281185

Abstract Article PDF–7.1M

Select item 1009797510.

Mechanosensitive mTORC1 signaling maintains lymphatic valves

Cansaran Saygili Demir, Amélie Sabine, Muyun Gong, Olivier Dormond, Tatiana V. Petrova

J Cell Biol. 2023 Jun 5; 222(6): e202207049. Published online 2023 Apr 10. doi: 10.1083/jcb.202207049

PMCID:: PMC10097975

Abstract Article PDF–9.6M

Select item 999191211.

Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer’s disease

Sebastiaan De Schepper, Judy Z. Ge, Gerard Crowley, Laís S. S. Ferreira, Dylan Garceau, Christina E. Toomey, Dimitra Sokolova, Javier Rueda-Carrasco, Sun-Hye Shin, Jung-Seok Kim, Thomas Childs, Tammaryn Lashley, Jemima J. Burden, Michael Sasner, Carlo Sala Frigerio, Steffen Jung, Soyon Hong

Nat Neurosci. 2023; 26(3): 406–415. Published online 2023 Feb 6. doi: 10.1038/s41593-023-01257-z

PMCID:: PMC9991912

Abstract Article PDF–7.1M

Select item 989982712.

Parenchymal border macrophages regulate CSF flow dynamics

Antoine Drieu, Siling Du, Steffen E. Storck, Justin Rustenhoven, Zachary Papadopoulos, Taitea Dykstra, Fenghe Zhong, Kyungdeok Kim, Susan Blackburn, Tornike Mamuladze, Oscar Harari, Celeste M. Karch, Randall J. Bateman, Richard Perrin, Martin Farlow, Jasmeer Chhatwal, Dominantly Inherited Alzheimer Network, Song Hu, Gwendalyn J. Randolph, Igor Smirnov, Jonathan Kipnis

Nature. Author manuscript; available in PMC 2023 May 9.

Published in final edited form as: Nature. 2022 Nov; 611(7936): 585–593. Published online 2022 Nov 9. doi: 10.1038/s41586-022-05397-3

PMCID:: PMC9899827

Abstract Article PDF–8.1M

Select item 989454713.

Latent CMV infection of Lymphatic endothelial cells is sufficient to drive CD8 T cell memory inflation

Michael W. Munks, Katherine Rott, Pavlo A. Nesterenko, Savannah M. Smart, Venasha Williams, Angela Tatum, Guangwu Xu, Tameka Smith, Susan E. Murray, Ann B. Hill

PLoS Pathog. 2023 Jan; 19(1): e1010351. Published online 2023 Jan 23. doi: 10.1371/journal.ppat.1010351

PMCID:: PMC9894547

Abstract Article PDF–1.3M

Select item 978882914.

Human Dectin-1 is O-glycosylated and serves as a ligand for C-type lectin receptor CLEC-2

Shojiro Haji, Taiki Ito, Carla Guenther, Miyako Nakano, Takashi Shimizu, Daiki Mori, Yasunori Chiba, Masato Tanaka, Sushil K Mishra, Janet A Willment, Gordon D Brown, Masamichi Nagae, Sho Yamasaki

eLife. 2022; 11: e83037. Published online 2022 Dec 8. doi: 10.7554/eLife.83037

PMCID:: PMC9788829

Abstract Article PDF–3.8M

Select item 971253615.

Deciphering the heterogeneity of the Lyve1⁺ perivascular macrophages in the mouse brain

C. Siret, M. van Lessen, J. Bavais, H. W. Jeong, S. K. Reddy Samawar, K. Kapupara, S. Wang, M. Simic, L. de Fabritus, A. Tchoghandjian, M. Fallet, H. Huang, S. Sarrazin, M. H. Sieweke, R. Stumm, L. Sorokin, R. H. Adams, S. Schulte-Merker, F. Kiefer, S. A. van de Pavert

Nat Commun. 2022; 13: 7366. Published online 2022 Nov 30. doi: 10.1038/s41467-022-35166-9

PMCID:: PMC9712536

Abstract Article PDF–10M

Select item 961390816.

Three-dimensional characterization of developing and adult ocular vasculature in mice using in toto clearing

Marie Darche, Anna Verschueren, Morgane Belle, Leyna Boucherit, Stéphane Fouquet, José Alain Sahel, Alain Chédotal, Ilaria Cascone, Michel Paques

Commun Biol. 2022; 5: 1135. Published online 2022 Oct 27. doi: 10.1038/s42003-022-04104-2

PMCID:: PMC9613908

Abstract Article PDF–13M

Select item 958899617.

Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b

Shikai Hu, Silvia Liu, Yu Bian, Minakshi Poddar, Sucha Singh, Catherine Cao, Jackson McGaughey, Aaron Bell, Levi L. Blazer, Jarret J. Adams, Sachdev S. Sidhu, Stephane Angers, Satdarshan P. Monga

Cell Rep Med. 2022 Oct 18; 3(10): 100754. Published online 2022 Oct 10. doi: 10.1016/j.xcrm.2022.100754