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Items: 1 to 20 of 55

1.
Suppressing UBE2N ameliorates Alzheimer's disease pathology through the clearance of amyloid beta
Chen Zhang, Qingqing Jia, Longhong Zhu, Junqi Hou, Xiang Wang, Dandan Li, Jiawei Zhang, Yiran Zhang, Su Yang, Zhuchi Tu, Xiao‐Xin Yan, Weili Yang, Shihua Li, Xiao‐Jiang Li, Peng Yin
Alzheimers Dement. 2024 Sep; 20(9): 6287–6304. Published online 2024 Jul 17. doi: 10.1002/alz.14122
PMCID:
PMC11497675
AbstractArticlePDF–16M
2.
Regulation and function of Id2 in plasmacytoid dendritic cells
Rachel L. Babcock, Yifan Zhou, Bhakti Patel, Taylor T. Chrisikos, Laura M. Kahn, Allison M. Dyevoich, Yusra B. Medik, Stephanie S. Watowich
Mol Immunol. Author manuscript; available in PMC 2024 Sep 11.
Published in final edited form as: Mol Immunol. 2022 Aug; 148: 6–17. Published online 2022 May 28. doi: 10.1016/j.molimm.2022.05.009
PMCID:
PMC11390127
AbstractArticlePDF–2.0M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
Deubiquitinase OTUD6A Regulates Innate Immune Response via Targeting UBC13
Zhiwei Li, Guanwen Li, Yunfei Li, Yujie Luo, Yuhan Jiang, Ziyu Zhang, Ziyi Zhou, Shengde Liu, Chen Wu, Fuping You
Viruses. 2023 Aug; 15(8): 1761. Published online 2023 Aug 18. doi: 10.3390/v15081761
PMCID:
PMC10458163
AbstractArticlePDF–3.2M
5.
SET7 methylates the deubiquitinase OTUB1 at Lys 122 to impair its binding to E2 enzyme UBC13 and relieve its suppressive role on ferroptosis
Hongyan Deng, Shuke Jia, Jinhua Tang, Fangjing Rong, Chenxi Xu, Xiaoyun Chen, Zixuan Wang, Chunchun Zhu, Xueyi Sun, Qian Liao, Wen Liu, Wenhua Li, Wuhan Xiao, Xing Liu
J Biol Chem. 2023 Apr; 299(4): 103054. Published online 2023 Feb 22. doi: 10.1016/j.jbc.2023.103054
PMCID:
PMC10040876
AbstractArticlePDF–3.0M
6.
The AAA‐ATPase ATAD1 and its partners promote degradation of desmin intermediate filaments in muscle
Dina Aweida, Shenhav Cohen
EMBO Rep. 2022 Dec; 23(12): e55175. Published online 2022 Oct 24. doi: 10.15252/embr.202255175
PMCID:
PMC9724657
AbstractArticlePDF–3.0M
7.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
8.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
9.
The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13
Floriana Mulas, Xu Wang, Shanshan Song, Gopala Nishanth, Wenjing Yi, Anna Brunn, Pia-Katharina Larsen, Berend Isermann, Ulrich Kalinke, Antonio Barragan, Michael Naumann, Martina Deckert, Dirk Schlüter
Cell Mol Immunol. 2021 Jun; 18(6): 1512–1527. Published online 2020 Feb 5. doi: 10.1038/s41423-020-0362-6
PMCID:
PMC8167118
AbstractArticlePDF–4.4M
10.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
11.
Conditional knockout of UBC13 produces disturbances in gait and spontaneous locomotion and exploration in mice
David F. Wozniak, Pamela Valnegri, Joshua T. Dearborn, Stephen C. Fowler, Azad Bonni
Sci Rep. 2019; 9: 4379. Published online 2019 Mar 13. doi: 10.1038/s41598-019-40714-3
PMCID:
PMC6416404
AbstractArticlePDF–2.1M
12.
UBE2N promotes melanoma growth via MEK/FRA1/SOX10 signaling
Anushka Dikshit, Yingai J Jin, Simone Degan, Jihwan Hwang, Matthew W. Foster, Chuan-Yuan Li, Jennifer Y. Zhang
Cancer Res. Author manuscript; available in PMC 2019 Nov 15.
Published in final edited form as: Cancer Res. 2018 Nov 15; 78(22): 6462–6472. Published online 2018 Sep 17. doi: 10.1158/0008-5472.CAN-18-1040
PMCID:
PMC6239934
AbstractArticlePDF–1.4M
13.
Tetrahydrobiopterin modulates ubiquitin conjugation to UBC13/UBE2N and proteasome activity by S-nitrosation
Jade Bailey, Simon Davis, Andrew Shaw, Marina Diotallevi, Roman Fischer, Matthew A. Benson, Hanneng Zhu, James Brown, Shoumo Bhattacharya, Benedikt M. Kessler, Keith M. Channon, Mark J. Crabtree
Sci Rep. 2018; 8: 14310. Published online 2018 Sep 25. doi: 10.1038/s41598-018-32481-4
PMCID:
PMC6156325
AbstractArticlePDF–10M
14.
Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis
Huiyuan Zhang, Haiyan S. Li, Emily J. Hillmer, Yang Zhao, Taylor T. Chrisikos, Hongbo Hu, Xiao Wu, Erika J. Thompson, Karen Clise-Dwyer, Karen A. Millerchip, Yue Wei, Nahum Puebla-Osorio, Saakshi Kaushik, Margarida A. Santos, Bin Wang, Guillermo Garcia-Manero, Jing Wang, Shao-Cong Sun, Stephanie S. Watowich
Proc Natl Acad Sci U S A. 2018 Mar 6; 115(10): E2311–E2319. Published online 2018 Feb 20. doi: 10.1073/pnas.1713889115
PMCID:
PMC5878002
AbstractArticlePDF–1.0M
15.
RNF8/UBC13 ubiquitin signaling suppresses synapse formation in the mammalian brain
Pamela Valnegri, Ju Huang, Tomoko Yamada, Yue Yang, Luis A. Mejia, Ha Y. Cho, Anna Oldenborg, Azad Bonni
Nat Commun. 2017; 8: 1271. Published online 2017 Nov 2. doi: 10.1038/s41467-017-01333-6
PMCID:
PMC5668370
AbstractArticlePDF–2.2M
16.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
17.
Oligomerization-primed coiled-coil domain interaction with Ubc13 confers processivity to TRAF6 ubiquitin ligase activity
Lin Hu, Jiafeng Xu, Xiaomei Xie, Yiwen Zhou, Panfeng Tao, Haidong Li, Xu Han, Chong Wang, Jian Liu, Pinglong Xu, Dante Neculai, Zongping Xia
Nat Commun. 2017; 8: 814. Published online 2017 Oct 9. doi: 10.1038/s41467-017-01290-0
PMCID:
PMC5634496
AbstractArticlePDF–3.4M
18.
Ube2D3 and Ube2N are essential for RIG-I-mediated MAVS aggregation in antiviral innate immunity
Yuheng Shi, Bofeng Yuan, Wenting Zhu, Rui Zhang, Lin Li, Xiaojing Hao, She Chen, Fajian Hou
Nat Commun. 2017; 8: 15138. Published online 2017 May 4. doi: 10.1038/ncomms15138
PMCID:
PMC5418627
AbstractArticlePDF–2.0M
19.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
20.
Inhibition of Ubc13-mediated Ubiquitination by GPS2 Regulates Multiple Stages of B Cell Development
Claudia Lentucci, Anna C. Belkina, Carly T. Cederquist, Michelle Chan, Holly E. Johnson, Sherry Prasad, Amanda Lopacinski, Barbara S. Nikolajczyk, Stefano Monti, Jennifer Snyder-Cappione, Bogdan Tanasa, M. Dafne Cardamone, Valentina Perissi
J Biol Chem. 2017 Feb 17; 292(7): 2754–2772. Published online 2016 Dec 30. doi: 10.1074/jbc.M116.755132
PMCID:
PMC5314172
AbstractArticlePDF–4.9M

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