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Select item 97088201.

FGFR2b signalling restricts lineage-flexible alveolar progenitors during mouse lung development and converges in mature alveolar type 2 cells

Matthew R. Jones, Arun Lingampally, Negah Ahmadvand, Lei Chong, Jin Wu, Jochen Wilhem, Ana Ivonne Vazquez-Armendariz, Meshal Ansari, Susanne Herold, David M. Ornitz, Herbert B. Schiller, Cho-Ming Chao, Jin-San Zhang, Gianni Carraro, Saverio Bellusci

Cell Mol Life Sci. 2022; 79(12): 609. Published online 2022 Nov 29. doi: 10.1007/s00018-022-04626-2

PMCID:: PMC9708820

Abstract Article PDF–3.1M

Select item 67294462.

Mitogen- and Stress-Activated Protein Kinase 1 Mediates cAMP Response Element-Binding Protein Phosphorylation and Activation by Neurotrophins

J. Simon, C. Arthur, Amy L. Fong, Jami M. Dwyer, Monika Davare, Ed Reese, Karl Obrietan, Soren Impey

J Neurosci. 2004 May 5; 24(18): 4324–4332. doi: 10.1523/JNEUROSCI.5227-03.2004

PMCID:: PMC6729446

Abstract Article PDF–526K

Select item 58181953.

Differential control of Toll-like receptor 4–induced interleukin-10 induction in macrophages and B cells reveals a role for p90 ribosomal S6 kinases

Ruhcha V. Sutavani, Iain R. Phair, Rebecca Barker, Alison McFarlane, Natalia Shpiro, Stuart Lang, Andrew Woodland, J. Simon C. Arthur

J Biol Chem. 2018 Feb 16; 293(7): 2302–2317. Published online 2017 Dec 11. doi: 10.1074/jbc.M117.805424

PMCID:: PMC5818195

Abstract Article PDF–3.9M

Select item 54584724.

MSK1 regulates transcriptional induction of Arc/Arg3.1 in response to neurotrophins

Chris J. Hunter, Judit Remenyi, Sonia A. Correa, Lucia Privitera, Kathleen M. S. E. Reyskens, Kirsty J. Martin, Rachel Toth, Bruno G. Frenguelli, J. Simon C. Arthur

FEBS Open Bio. 2017 Jun; 7(6): 821–834. Published online 2017 May 11. doi: 10.1002/2211-5463.12232

PMCID:: PMC5458472

Abstract Article PDF–746K

Select item 51920815.

Beta Interferon Production Is Regulated by p38 Mitogen-Activated Protein Kinase in Macrophages via both MSK1/2- and Tristetraprolin-Dependent Pathways

Victoria A. McGuire, Dalya Rosner, Olga Ananieva, Ewan A. Ross, Suzanne E. Elcombe, Shaista Naqvi, Mirjam M. W. van den Bosch, Claire E. Monk, Tamara Ruiz-Zorrilla Diez, Andrew R. Clark, J. Simon C. Arthur

Mol Cell Biol. 2017 Jan 1; 37(1): e00454-16. Prepublished online 2016 Oct 17. Published online 2016 Dec 19. doi: 10.1128/MCB.00454-16

PMCID:: PMC5192081

Abstract Article PDF–2.8M

Select item 51563596.

The Chromatin Modifier MSK1/2 Suppresses Endocrine Cell Fates during Mouse Pancreatic Development

Neha Bhat, Jeehye Park, Huda Y. Zoghbi, J. Simon C. Arthur, Kenneth S. Zaret

PLoS One. 2016; 11(12): e0166703. Published online 2016 Dec 14. doi: 10.1371/journal.pone.0166703

PMCID:: PMC5156359

Abstract Article PDF–3.9M

Select item 50486777.

Mitogen and stress-activated kinases 1/2 regulate ischemia-induced hippocampal progenitor cell proliferation and neurogenesis

Kate Karelina, Yujia Liu, Diego Alzate-Correa, Kelin L. Wheaton, Kari R. Hoyt, J. Simon C. Arthur, Karl Obrietan

Neuroscience. Author manuscript; available in PMC 2016 Oct 4.

Published in final edited form as: Neuroscience. 2015 Jan 29; 285: 292–302. Published online 2014 Nov 14. doi: 10.1016/j.neuroscience.2014.10.053

PMCID:: PMC5048677

Abstract Article PDF–1.3M

Select item 49313238.

miR-93 regulates Msk2-mediated chromatin remodelling in diabetic nephropathy

Shawn S. Badal, Yin Wang, Jianyin Long, David L. Corcoran, Benny H. Chang, Luan D. Truong, Yashpal S. Kanwar, Paul A. Overbeek, Farhad R. Danesh

Nat Commun. 2016; 7: 12076. Published online 2016 Jun 28. doi: 10.1038/ncomms12076

PMCID:: PMC4931323

Abstract Article PDF–3.2M

Select item 46614339.

Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2

Elisabeth Lang, Rosi Bissinger, Abul Fajol, Madhuri S. Salker, Yogesh Singh, Christine Zelenak, Mehrdad Ghashghaeinia, Shuchen Gu, Kashif Jilani, Adrian Lupescu, Kathleen M. S. E. Reyskens, Teresa F. Ackermann, Michael Föller, Erwin Schleicher, William P. Sheffield, J. Simon C. Arthur, Florian Lang, Syed M. Qadri

Sci Rep. 2015; 5: 17316. Published online 2015 Nov 27. doi: 10.1038/srep17316

PMCID:: PMC4661433

Abstract Article PDF–1.0M

Select item 414047110.

Comparison of epigenetic mediator expression and function in mouse and human embryonic blastomeres

Shawn L. Chavez, Sohyun L. McElroy, Nancy L. Bossert, Christopher J. De Jonge, Maria Vera Rodriguez, Denise E. Leong, Barry Behr, Lynn M. Westphal, Renee A. Reijo Pera

Hum Mol Genet. 2014 Sep 15; 23(18): 4970–4984. Published online 2014 May 12. doi: 10.1093/hmg/ddu212

PMCID:: PMC4140471

Abstract Article PDF–2.3M

Select item 407349411.

The Central Role of EED in the Orchestration of Polycomb Group Complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Nat Commun. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127

PMCID:: PMC4073494

Abstract Article PDF–2.1M

Select item 403878712.

The Ah Receptor Recruits IKKα to Its Target Binding Motifs to Phosphorylate Serine-10 in Histone H3 Required for Transcriptional Activation

Hisaka Kurita, Michael Schnekenburger, Jerald L. Ovesen, Ying Xia, Alvaro Puga

Toxicol Sci. 2014 May 1; 139(1): 121–132. Published online 2014 Feb 13. doi: 10.1093/toxsci/kfu027

PMCID:: PMC4038787

Abstract Article PDF–1.9M

Select item 402015413.

Genetic screens reveal RAS/MAPK/MSK1 modulate ataxin 1 protein levels and toxicity in SCA1

Jeehye Park, Ismael Al-Ramahi, Qiumin Tan, Nissa Mollema, Javier R. Diaz-Garcia, Tatiana Gallego-Flores, Hsiang-Chih Lu, Sarita Lagalwar, Lisa Duvick, Hyojin Kang, Yoontae Lee, Paymaan Jafar-Nejad, Layal S. Sayegh, Ronald Richman, Xiuyun Liu, Yan Gao, Chad A. Shaw, J. Simon C. Arthur, Harry T. Orr, Thomas F. Westbrook, Juan Botas, Huda Y. Zoghbi

Nature. Author manuscript; available in PMC 2014 May 14.

Published in final edited form as: Nature. 2013 Jun 20; 498(7454): 325–331. Published online 2013 May 29. doi: 10.1038/nature12204

PMCID:: PMC4020154

Abstract Article PDF–4.3M

Select item 381189914.

Cross Talk between the Akt and p38α Pathways in Macrophages Downstream of Toll-Like Receptor Signaling

Victoria A. McGuire, Alexander Gray, Claire E. Monk, Susana G. Santos, Keunwook Lee, Anna Aubareda, Jonathan Crowe, Natalia Ronkina, Jessica Schwermann, Ian H. Batty, Nick R. Leslie, Jonathan L. E. Dean, Stephen J. O'Keefe, Mark Boothby, Matthias Gaestel, J. Simon C. Arthur

Mol Cell Biol. 2013 Nov; 33(21): 4152–4165. doi: 10.1128/MCB.01691-12

PMCID:: PMC3811899

Abstract Article PDF–1.9M

Select item 363722115.

miR-132/212 Knockout Mice Reveal Roles for These miRNAs in Regulating Cortical Synaptic Transmission and Plasticity

Judit Remenyi, Mirjam W. M. van den Bosch, Oleg Palygin, Rajen B. Mistry, Colin McKenzie, Andrew Macdonald, Gyorgy Hutvagner, J. Simon C. Arthur, Bruno G. Frenguelli, Yuriy Pankratov

PLoS One. 2013; 8(4): e62509. Published online 2013 Apr 26. doi: 10.1371/journal.pone.0062509

PMCID:: PMC3637221

Abstract Article PDF–1.6M

Select item 362426816.

MSK1 and MSK2 Inhibit Lipopolysaccharide-Induced Prostaglandin Production via an Interleukin-10 Feedback Loop

Kirsty F. MacKenzie, Mirjam W. M. Van Den Bosch, Shaista Naqvi, Suzanne E. Elcombe, Victoria A. McGuire, Alastair D. Reith, Perry J. Blackshear, Jonathan L. E. Dean, J. Simon C. Arthur

Mol Cell Biol. 2013 Apr; 33(7): 1456–1467. doi: 10.1128/MCB.01690-12

PMCID:: PMC3624268

Abstract Article PDF–1.8M

Select item 362052417.

PGE₂ Induces Macrophage IL-10 Production and a Regulatory-like Phenotype via a Protein Kinase A–SIK–CRTC3 Pathway

Kirsty F. MacKenzie, Kristopher Clark, Shaista Naqvi, Victoria A. McGuire, Gesa Nöehren, Yosua Kristariyanto, Mirjam van den Bosch, Manikhandan Mudaliar, Pierre C. McCarthy, Michael J. Pattison, Patrick G. A. Pedrioli, Geoff J. Barton, Rachel Toth, Alan Prescott, J. Simon C. Arthur

J Immunol. 2013 Jan 15; 190(2): 565–577. Published online 2013 Jan 15. doi: 10.4049/jimmunol.1202462

PMCID:: PMC3620524

Abstract Article PDF–1.6M

Select item 360624218.

Dectin-1 Regulates IL-10 Production via a MSK1/2 and CREB Dependent Pathway and Promotes the Induction of Regulatory Macrophage Markers

Suzanne E. Elcombe, Shaista Naqvi, Mirjam W. M. Van Den Bosch, Kirsty F. MacKenzie, Francesca Cianfanelli, Gordon D. Brown, J. Simon C. Arthur

PLoS One. 2013; 8(3): e60086. Published online 2013 Mar 22. doi: 10.1371/journal.pone.0060086

PMCID:: PMC3606242

Abstract Article PDF–2.3M

Select item 357574719.

Mitogen and stress-activated protein kinase 1 (MSK1) modulates photic entrainment of the suprachiasmatic circadian clock

Ruifeng Cao, Greg Q. Butcher, Kate Karelina, J. Simon C. Arthur, Karl Obrietan

Eur J Neurosci. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Eur J Neurosci. 2013 Jan; 37(1): 130–140. Published online 2012 Nov 6. doi: 10.1111/ejn.12028

PMCID:: PMC3575747

Abstract Article PDF–2.3M

Select item 357574420.

Mitogen- and stress-activated kinases regulate progenitor cell proliferation and neuron development in the adult dentate gyrus

Yun-Sik Choi, Kate Karelina, Diego Alzate-Correa, Kari R. Hoyt, Soren Impey, J. Simon Arthur, Karl Obrietan

J Neurochem. Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: J Neurochem. 2012 Dec; 123(5): 676–688. Published online 2012 Oct 25. doi: 10.1111/jnc.12035

PMCID:: PMC3575744

Abstract Article PDF–1.5M

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