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Items: 1 to 20 of 52

1.
TACI haploinsufficiency protects against BAFF-driven humoral autoimmunity in mice
Holly M. Jacobs, Tanvi Arkatkar, Samuel W. Du, Nicole E. Scharping, Jonathan Woods, Quan-Zhen Li, Kelly L. Hudkins, Charles E. Alpers, David J. Rawlings, Shaun W. Jackson
Eur J Immunol. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Eur J Immunol. 2021 Sep; 51(9): 2225–2236. Published online 2021 Jun 27. doi: 10.1002/eji.202149244
PMCID:
PMC8410679
AbstractArticlePDF–1.0M
2.
TNFRSF13B polymorphisms counter microbial adaptation to enteric IgA
Jeffrey L. Platt, Mayara Garcia de Mattos Barbosa, Daniel Huynh, Adam R. Lefferts, Juhi Katta, Cyra Kharas, Peter Freddolino, Christine M. Bassis, Christiane Wobus, Raif Geha, Richard Bram, Gabriel Nunez, Nobuhiko Kamada, Marilia Cascalho
JCI Insight. 2021 Jul 22; 6(14): e148208. Published online 2021 Jul 22. doi: 10.1172/jci.insight.148208
PMCID:
PMC8410086
AbstractArticlePDF–2.7M
3.
Circulating CD138 enhances disease progression by augmenting autoreactive antibody production in a mouse model of systemic lupus erythematosus
Lunhua Liu, Mustafa Akkoyunlu
J Biol Chem. 2021 Sep; 297(3): 101053. Published online 2021 Aug 6. doi: 10.1016/j.jbc.2021.101053
PMCID:
PMC8405997
AbstractArticlePDF–2.8M
4.
A BAFF/APRIL axis regulates obesogenic diet-driven weight gain
Calvin C. Chan, Isaac T. W. Harley, Paul T. Pfluger, Aurelien Trompette, Traci E. Stankiewicz, Jessica L. Allen, Maria E. Moreno-Fernandez, Michelle S. M. A. Damen, Jarren R. Oates, Pablo C. Alarcon, Jessica R. Doll, Matthew J. Flick, Leah M. Flick, Joan Sanchez-Gurmaches, Rajib Mukherjee, Rebekah Karns, Michael Helmrath, Thomas H. Inge, Stuart P. Weisberg, Sünje J. Pamp, David A. Relman, Randy J. Seeley, Matthias H. Tschöp, Christopher L. Karp, Senad Divanovic
Nat Commun. 2021; 12: 2911. Published online 2021 May 18. doi: 10.1038/s41467-021-23084-1
PMCID:
PMC8131685
AbstractArticlePDF–2.0M
5.
TACI Constrains TH17 Pathogenicity and Protects against Gut Inflammation
Andy Hee-Meng Tan, Gloria Hoi Wan Tso, Biyan Zhang, Pei-Yun Teo, Xijun Ou, Sze-Wai Ng, Alex Xing Fah Wong, Sean Jing Xiang Tan, Arleen Sanny, Susana Soo-Yeon Kim, Alison P. Lee, Shengli Xu, Kong-Peng Lam
iScience. 2020 Nov 20; 23(11): 101707. Published online 2020 Oct 22. doi: 10.1016/j.isci.2020.101707
PMCID:
PMC7653077
AbstractArticlePDF–5.8M
6.
B cell ADAM17 Controls T cell Independent Humoral Immune Responses through Regulation of TACI and CD138
Joseph C. Lownik, Jessica Wimberly, Leila Takahashi-Ruiz, Rebecca K. Martin
Biochem Biophys Res Commun. Author manuscript; available in PMC 2021 Feb 5.
Published in final edited form as: Biochem Biophys Res Commun. 2020 Feb 5; 522(2): 442–447. Published online 2019 Nov 23. doi: 10.1016/j.bbrc.2019.11.124
PMCID:
PMC6957701
AbstractArticlePDF–896K
7.
TACI expression and plasma cell differentiation are impaired in the absence of functional IκBNS
Sharesta Khoenkhoen, Elina Erikson, Monika Ádori, Julian M Stark, Jean L Scholz, Michael P Cancro, Gabriel K Pedersen, Gunilla B Karlsson Hedestam
Immunol Cell Biol. 2019 May-Jun; 97(5): 485–497. Published online 2019 Jan 30. doi: 10.1111/imcb.12228
PMCID:
PMC6850186
AbstractArticlePDF–2.2M
8.
TWE-PRIL reverse signalling suppresses sympathetic axon growth and tissue innervation
Laura Howard, Erin Wosnitzka, Darian Okakpu, Matthew A. White, Sean Wyatt, Alun M. Davies
Development. 2018 Nov 15; 145(22): dev165936. Published online 2018 Nov 19. doi: 10.1242/dev.165936
PMCID:
PMC6262789
AbstractArticle
9.
TACI Contributes to Plasmodium yoelii Host Resistance by Controlling T Follicular Helper Cell Response and Germinal Center Formation
Marcela Parra, Jiyeon Yang, Megan Weitner, Steven Derrick, Amy Yang, Thomas Schmidt, Balwan Singh, Alberto Moreno, Mustafa Akkoyunlu
Front Immunol. 2018; 9: 2612. Published online 2018 Nov 9. doi: 10.3389/fimmu.2018.02612
PMCID:
PMC6237915
AbstractArticlePDF–2.4M
10.
TACI-Deficient Macrophages Protect Mice Against Metaflammation and Obesity-Induced Dysregulation of Glucose Homeostasis
Lunhua Liu, Karen Etsuko Inouye, Windy Rose Allman, Adam Steven Coleman, Shafiuddin Siddiqui, Gökhan Siddik Hotamisligil, Mustafa Akkoyunlu
Diabetes. 2018 Aug; 67(8): 1589–1603. Published online 2018 Jun 5. doi: 10.2337/db17-1089
PMCID:
PMC6054430
AbstractArticlePDF–2.1M
11.
Delayed onset of autoreactive antibody production and M2-skewed macrophages contribute to improved survival of TACI deficient MRL-Fas/Lpr mouse
Lunhua Liu, Windy Rose Allman, Adam Steven Coleman, Kazuyo Takeda, Tsai-Lien Lin, Mustafa Akkoyunlu
Sci Rep. 2018; 8: 1308. Published online 2018 Jan 22. doi: 10.1038/s41598-018-19827-8
PMCID:
PMC5778001
AbstractArticlePDF–6.7M
12.
mTOR intersects antibody-inducing signals from TACI in marginal zone B cells
Jordi Sintes, Maurizio Gentile, Shuling Zhang, Yolanda Garcia-Carmona, Giuliana Magri, Linda Cassis, Daniel Segura-Garzón, Alessandra Ciociola, Emilie K. Grasset, Sabrina Bascones, Laura Comerma, Marc Pybus, David Lligé, Irene Puga, Cindy Gutzeit, Bing He, Wendy DuBois, Marta Crespo, Julio Pascual, Anna Mensa, Juan Ignacio Aróstegui, Manel Juan, Jordi Yagüe, Sergi Serrano, Josep Lloreta, Eric Meffre, Michael Hahne, Charlotte Cunningham-Rundles, Beverly A. Mock, Andrea Cerutti
Nat Commun. 2017; 8: 1462. Published online 2017 Nov 13. doi: 10.1038/s41467-017-01602-4
PMCID:
PMC5684130
AbstractArticlePDF–3.4M
13.
A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens
Vishal J. Sindhava, Michael A. Oropallo, Krishna Moody, Martin Naradikian, Lauren E. Higdon, Lin Zhou, Arpita Myles, Nathaniel Green, Kerstin Nündel, William Stohl, Amanda M. Schmidt, Wei Cao, Stephanie Dorta-Estremera, Taku Kambayashi, Ann Marshak-Rothstein, Michael P. Cancro
J Clin Invest. 2017 May 1; 127(5): 1651–1663. Published online 2017 Mar 27. doi: 10.1172/JCI89931
PMCID:
PMC5409796
AbstractArticlePDF–2.3M
14.
Heterozygosity for TACI A144E causes haploinsufficiency and pneumococcal susceptibility in mice
Haifa H. Jabara, John J. Lee, Erin Janssen, Sumana Ullas, Kyriaki Liadaki, Lilit Garibyan, Halli Benson, Tatyana Sannikova, Richard Bram, Lennart Hammarstrom, Anthony C. Cruz, Richard Siegel, John Manis, Richard Malley, Raif S. Geha
J Allergy Clin Immunol. Author manuscript; available in PMC 2018 Apr 1.
Published in final edited form as: J Allergy Clin Immunol. 2017 Apr; 139(4): 1293–1301.e4. Published online 2016 Sep 5. doi: 10.1016/j.jaci.2016.07.028
PMCID:
PMC5337448
AbstractArticlePDF–1.1M
15.
Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line
Van Trung Chu, Robin Graf, Tristan Wirtz, Timm Weber, Jeremy Favret, Xun Li, Kerstin Petsch, Ngoc Tung Tran, Michael H. Sieweke, Claudia Berek, Ralf Kühn, Klaus Rajewsky
Proc Natl Acad Sci U S A. 2016 Nov 1; 113(44): 12514–12519. Published online 2016 Oct 11. doi: 10.1073/pnas.1613884113
PMCID:
PMC5098665
AbstractArticlePDF–1.5M
16.
Increased expression of TACI on NOD B cells results in germinal centre reaction anomalies, enhanced plasma cell differentiation and immunoglobulin production
Viqar S. Banday, Radha Thyagarajan, Mia Sundström, Kristina Lejon
Immunology. 2016 Nov; 149(3): 297–305. Published online 2016 Aug 23. doi: 10.1111/imm.12651
PMCID:
PMC5046060
AbstractArticlePDF–825K
17.
BAFF promotes autoantibody production via TACI-dependent activation of transitional B cells
Holly M. Jacobs, Christopher D. Thouvenel, Sarah Leach, Tanvi Arkatkar, Genita Metzler, Nicole E. Scharping, Nikita S. Kolhatkar, David J. Rawlings, Shaun W. Jackson
J Immunol. Author manuscript; available in PMC 2017 May 1.
Published in final edited form as: J Immunol. 2016 May 1; 196(9): 3525–3531. Published online 2016 Mar 28. doi: 10.4049/jimmunol.1600017
PMCID:
PMC4868625
AbstractArticlePDF–1.5M
18.
The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells
Damien Saulep-Easton, Fabien B. Vincent, Pin Shie Quah, Andrew Wei, Stephen B. Ting, Carlo M. Croce, Constantine Tam, Fabienne Mackay
Leukemia. Author manuscript; available in PMC 2016 May 18.
Published in final edited form as: Leukemia. 2016 Jan; 30(1): 163–172. Published online 2015 Jul 3. doi: 10.1038/leu.2015.174
PMCID:
PMC4606984
AbstractArticlePDF–1.9M
19.
TACI deficiency leads to alternatively activated macrophage phenotype and susceptibility to Leishmania infection
Windy R. Allman, Ranadhir Dey, Lunhua Liu, Shafiuddin Siddiqui, Adam S. Coleman, Parna Bhattacharya, Masahide Yano, Kadriye Uslu, Kazuyo Takeda, Hira L. Nakhasi, Mustafa Akkoyunlu
Proc Natl Acad Sci U S A. 2015 Jul 28; 112(30): E4094–E4103. Published online 2015 Jul 13. doi: 10.1073/pnas.1421580112
PMCID:
PMC4522803
AbstractArticlePDF–1.4M
20.
Stoichiometry of Heteromeric BAFF and APRIL Cytokines Dictates Their Receptor Binding and Signaling Properties
Sonia Schuepbach-Mallepell, Dolon Das, Laure Willen, Michele Vigolo, Aubry Tardivel, Luc Lebon, Christine Kowalczyk-Quintas, Josquin Nys, Cristian Smulski, Timothy S. Zheng, Klaus Maskos, Alfred Lammens, Xuliang Jiang, Henry Hess, Seng-Lai Tan, Pascal Schneider
J Biol Chem. 2015 Jun 26; 290(26): 16330–16342. Published online 2015 May 7. doi: 10.1074/jbc.M115.661405
PMCID:
PMC4481231
AbstractArticlePDF–2.6M

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