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Items: 1 to 20 of 38

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Targeting of oncogenic AAA-ATPase TRIP13 reduces progression of pancreatic ductal adenocarcinoma
Farrukh Afaq, Sumit Agarwal, Prachi Bajpai, Sameer Al Diffalha, Hyung-Gyoon Kim, Shajan Peter, Moh'd Khushman, Subhash C Chauhan, Priyabrata Mukherjee, Sooryanarayana Varambally, Upender Manne
Neoplasia. 2024 Jan; 47: 100951. Published online 2023 Nov 30. doi: 10.1016/j.neo.2023.100951
PMCID:
PMC10716004
AbstractArticlePDF–31M
3.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
4.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
5.
TRIP13 modulates protein deubiquitination and accelerates tumor development and progression of B cell malignancies
Can Li, Jiliang Xia, Reinaldo Franqui-Machin, Fangping Chen, Yanjuan He, Timothy Cody Ashby, Feixiang Teng, Hongwei Xu, Dingxiao Liu, Dongzheng Gai, Sarah K. Johnson, Frits van Rhee, Siegfried Janz, John D. Shaughnessy, Jr., Guido Tricot, Ivana Frech, Fenghuang Zhan
J Clin Invest. 2021 Jul 15; 131(14): e146893. Published online 2021 Jul 15. doi: 10.1172/JCI146893
PMCID:
PMC8279583
AbstractArticlePDF–7.1M
6.
SKP1 drives the prophase I to metaphase I transition during male meiosis
Yongjuan Guan, N. Adrian Leu, Jun Ma, Lukáš Chmátal, Gordon Ruthel, Jordana C. Bloom, Michael A. Lampson, John C. Schimenti, Mengcheng Luo, P. Jeremy Wang
Sci Adv. 2020 Mar; 6(13): eaaz2129. Published online 2020 Mar 25. doi: 10.1126/sciadv.aaz2129
PMCID:
PMC7096161
AbstractArticlePDF–3.1M
7.
The DNA damage checkpoint eliminates mouse oocytes with chromosome synapsis failure
Vera D. Rinaldi, Ewelina Bolcun-Filas, Hiroshi Kogo, Hiroki Kurahashi, John C. Schimenti
Mol Cell. Author manuscript; available in PMC 2018 Sep 21.
Published in final edited form as: Mol Cell. 2017 Sep 21; 67(6): 1026–1036.e2. Published online 2017 Aug 24. doi: 10.1016/j.molcel.2017.07.027
PMCID:
PMC5621520
AbstractArticlePDF–3.0M
8.
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program
John P. Sundberg, Soheil S. Dadras, Kathleen A. Silva, Victoria E. Kennedy, Gaven Garland, Stephen A. Murray, Beth A. Sundberg, Paul N. Schofield, C. Herbert Pratt
PLoS One. 2017; 12(7): e0180682. Published online 2017 Jul 10. doi: 10.1371/journal.pone.0180682
PMCID:
PMC5503261
AbstractArticlePDF–31M
9.
p53 and TAp63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes
Marina Marcet-Ortega, Sarai Pacheco, Ana Martínez-Marchal, Helena Castillo, Elsa Flores, Maria Jasin, Scott Keeney, Ignasi Roig
PLoS Genet. 2017 Jun; 13(6): e1006845. Published online 2017 Jun 15. doi: 10.1371/journal.pgen.1006845
PMCID:
PMC5491309
AbstractArticlePDF–26M
10.
TRIP13 impairs mitotic checkpoint surveillance and is associated with poor prognosis in multiple myeloma
Yi Tao, Guang Yang, Hongxing Yang, Dongliang Song, Liangning Hu, Bingqian Xie, Houcai Wang, Lu Gao, Minjie Gao, Hongwei Xu, Zhijian Xu, Xiaosong Wu, Yiwen Zhang, Weiliang Zhu, Fenghuang Zhan, Jumei Shi
Oncotarget. 2017 Apr 18; 8(16): 26718–26731. Published online 2017 Feb 1. doi: 10.18632/oncotarget.14957
PMCID:
PMC5432292
AbstractArticlePDF–3.3M
11.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
12.
The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase
Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong
EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500
PMCID:
PMC5341520
AbstractArticlePDF–1.1M
13.
TRIP13-deficient tubular epithelial cells are susceptible to apoptosis following acute kidney injury
Jeffrey D. Pressly, Taketsugu Hama, Shannon O’ Brien, Kevin R. Regner, Frank Park
Sci Rep. 2017; 7: 43196. Published online 2017 Mar 3. doi: 10.1038/srep43196
PMCID:
PMC5335694
AbstractArticlePDF–1.8M
14.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
15.
The ATM Signaling Cascade Promotes Recombination-Dependent Pachytene Arrest in Mouse Spermatocytes
Sarai Pacheco, Marina Marcet-Ortega, Julian Lange, Maria Jasin, Scott Keeney, Ignasi Roig
PLoS Genet. 2015 Mar; 11(3): e1005017. Published online 2015 Mar 13. doi: 10.1371/journal.pgen.1005017
PMCID:
PMC4358828
AbstractArticlePDF–22M
16.
TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer
Rajat Banerjee, Nickole Russo, Min Liu, Venkatesha Basrur, Emily Bellile, Nallasivam Palanisamy, Christina S. Scanlon, Elizabeth van Tubergen, Ronald C. Inglehart, Tarek Metwally, Ram-Shankar Mani, Anastasia Yocum, Mukesh K. Nyati, Rogerio M. Castilho, Sooryanarayana Varambally, Arul M. Chinnaiyan, Nisha J. D’Silva
Nat Commun. Author manuscript; available in PMC 2015 Jan 31.
Published in final edited form as: Nat Commun. 2014; 5: 4527. Published online 2014 Jul 31. doi: 10.1038/ncomms5527
Correction in:
Nat Commun. 2016; 7: 10726.
PMCID:
PMC4130352
AbstractArticlePDF–4.1M
17.
Reversal of female infertility by Chk2 ablation reveals the oocyte DNA damage checkpoint pathway
Ewelina Bolcun-Filas, Vera D. Rinaldi, Michelle E. White, John C. Schimenti
Science. Author manuscript; available in PMC 2015 Jan 31.
Published in final edited form as: Science. 2014 Jan 31; 343(6170): 533–536. doi: 10.1126/science.1247671
PMCID:
PMC4048839
AbstractArticlePDF–1.3M
18.
Dynamics of DOT1L localization and H3K79 methylation during meiotic prophase I in mouse spermatocytes
David Ontoso, Liisa Kauppi, Scott Keeney, Pedro A. San-Segundo
Chromosoma. Author manuscript; available in PMC 2014 Sep 1.
Published in final edited form as: Chromosoma. 2014 Mar; 123(0): 147–164. Published online 2013 Oct 9. doi: 10.1007/s00412-013-0438-5
PMCID:
PMC3969405
AbstractArticlePDF–7.9M
19.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
20.
CENTRAL REGION COMPONENT1, a Novel Synaptonemal Complex Component, Is Essential for Meiotic Recombination Initiation in Rice
Chunbo Miao, Ding Tang, Honggen Zhang, Mo Wang, Yafei Li, Shuzhu Tang, Hengxiu Yu, Minghong Gu, Zhukuan Cheng
Plant Cell. 2013 Aug; 25(8): 2998–3009. Published online 2013 Aug 13. doi: 10.1105/tpc.113.113175
PMCID:
PMC3784594
AbstractArticlePDF–1.6M

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