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Items: 1 to 20 of 1062

1.
Expression of HIF1α in intestinal epithelium restricts arthritis inflammation by inhibiting RIPK3-induced cell death machinery
Pang Lyu, Jinming Wen, Wenshuo Zhang, Ning Liu, Iris Stolzer, Andreas Gießl, Yewei Jia, Daniele Mauro, Fulin Zhang, Francesco Ciccia, Didier Soulat, Claudia Günther, Georg Schett, Aline Bozec
Ann Rheum Dis. 2024 Aug; 83(8): 984–997. Published online 2024 Mar 19. doi: 10.1136/ard-2023-224491
PMCID:
PMC11287550
AbstractArticlePDF–4.1M
2.
Differential but complementary roles of HIF-1α and HIF-2α in the regulation of bone homeostasis
Sun Young Lee, Su-Jin Kim, Ka Hyon Park, Gyuseok Lee, Youngsoo Oh, Je-Hwang Ryu, Yun Hyun Huh
Commun Biol. 2024; 7: 892. Published online 2024 Jul 23. doi: 10.1038/s42003-024-06581-z
PMCID:
PMC11263705
AbstractArticlePDF–3.3M
3.
Vhl safeguards thymic epithelial cell identity and thymopoietic capacity by constraining Hif1a activity during development
Christiane Grammer, Julia A. Komorowska, Jeremy B. Swann
iScience. 2024 Jul 19; 27(7): 110258. Published online 2024 Jun 13. doi: 10.1016/j.isci.2024.110258
PMCID:
PMC11261450
AbstractArticlePDF–11M
4.
Multiple roles for hypoxia inducible factor 1-alpha in airway epithelial cells during mucormycosis
Povilas Kavaliauskas, Yiyou Gu, Naushaba Hasin, Karen T. Graf, Abdullah Alqarihi, Amol C. Shetty, Carrie McCracken, Thomas J. Walsh, Ashraf S. Ibrahim, Vincent M. Bruno
Nat Commun. 2024; 15: 5282. Published online 2024 Jun 20. doi: 10.1038/s41467-024-49637-8
PMCID:
PMC11190229
AbstractArticlePDF–3.7M
5.
Iron deficiency affects oxygen transport and activates HIF1 signaling pathway to regulate phenotypic transformation of VSMC in aortic dissection
Yuanyang Chen, Xu Li, Zhiwei Wang, Shun Yuan, Xiaoyan Shen, Xiaoping Xie, Kai Xing, Qingyi Zhu
Mol Med. 2024; 30: 90. Published online 2024 Jun 17. doi: 10.1186/s10020-024-00859-y
PMCID:
PMC11184844
AbstractArticlePDF–6.9M
6.
MiR-18a affects hypoxia induced glucose metabolism transition in HT22 hippocampal neuronal cell line through the Hif1a gene
Chuncheng Liu, Gehui Liu, Xinyang Zuo, Donghui Qu, Yefeng Sun, Linan Liu, Xiujuan Zhao, Jun Li, Lu Cai
BMC Neurol. 2024; 24: 204. Published online 2024 Jun 15. doi: 10.1186/s12883-024-03717-w
PMCID:
PMC11179257
AbstractArticlePDF–3.0M
7.
The transcription factor HIF-1α in NKp46+ ILCs limits chronic intestinal inflammation and fibrosis
Eric Nelius, Zheng Fan, Michal Sobecki, Ewelina Krzywinska, Shunmugam Nagarajan, Irina Ferapontova, Dagmar Gotthardt, Norihiko Takeda, Veronika Sexl, Christian Stockmann
Life Sci Alliance. 2024 Sep; 7(9): e202402593. Published online 2024 Jun 14. doi: 10.26508/lsa.202402593
PMCID:
PMC11178940
AbstractArticlePDF–3.1M
8.
Alternative splicing of CEACAM1 by Hypoxia-Inducible Factor–1α enhances tolerance to hepatic ischemia in mice and humans
Kenneth J. Dery, Hidenobu Kojima, Shoichi Kageyama, Kentaro Kadono, Hirofumi Hirao, Brian Cheng, Yuan Zhai, Douglas G. Farmer, Fady M. Kaldas, Xiaoyi Yuan, Holger K. Eltzschiasg, Jerzy W. Kupiec-Weglinski
Sci Transl Med. Author manuscript; available in PMC 2024 Jun 10.
Published in final edited form as: Sci Transl Med. 2023 Aug 2; 15(707): eadf2059. Published online 2023 Aug 2. doi: 10.1126/scitranslmed.adf2059
PMCID:
PMC11164245
AbstractArticlePDF–2.9M
9.
HIF-1 is involved in high glucose-induced paracellular permeability of brain endothelial cells
Jingqi Yan, Ziyan Zhang, Honglian Shi
Cell Mol Life Sci. 2012 Jan; 69(1): 115–128. Published online 2011 May 27. doi: 10.1007/s00018-011-0731-5
PMCID:
PMC11115066
AbstractArticlePDF–904K
10.
The HIF-1 transcription complex is essential for translational control of myeloid hematopoietic cell function by maintaining mTOR phosphorylation
Inna M. Yasinska, Bernhard F. Gibbs, Gurprit S. Lall, Vadim V. Sumbayev
Cell Mol Life Sci. 2014 Feb; 71(4): 699–710. Published online 2013 Jul 20. doi: 10.1007/s00018-013-1421-2
PMCID:
PMC11113144
AbstractArticlePDF–886K
11.
Ambient oxygen levels regulate intestinal dysbiosis and GVHD severity after allogeneic stem cell transplantation
Keisuke Seike, Anders Kiledal, Hideaki Fujiwara, Israel Henig, Marina Burgos da Silva, Marcel R.M. van den Brink, Robert Hein, Matthew Hoostal, Chen Liu, Katherine Oravecz-Wilson, Emma Lauder, Lu Li, Yaping Sun, Thomas M. Schmidt, Yatrik M. Shah, Robert R. Jenq, Gregory Dick, Pavan Reddy
Immunity. Author manuscript; available in PMC 2024 May 16.
Published in final edited form as: Immunity. 2023 Feb 14; 56(2): 353–368.e6. Published online 2023 Feb 2. doi: 10.1016/j.immuni.2023.01.007
PMCID:
PMC11098523
AbstractArticlePDF–3.0M
12.
Foxp1 suppresses cortical angiogenesis and attenuates HIF-1alpha signaling to promote neural progenitor cell maintenance
Jessie E Buth, Catherine E Dyevich, Alexandra Rubin, Chengbing Wang, Lei Gao, Tessa Marks, Michael RM Harrison, Jennifer H Kong, M Elizabeth Ross, Bennett G Novitch, Caroline Alayne Pearson
EMBO Rep. 2024 May; 25(5): 2202–2219. Published online 2024 Apr 10. doi: 10.1038/s44319-024-00131-8
PMCID:
PMC11094073
AbstractArticlePDF–13M
13.
Sequestosome 1 (p62) mitigates hypoxia-induced cardiac dysfunction by stabilizing hypoxia-inducible factor 1α and nuclear factor erythroid 2-related factor 2
Rajeshwary Ghosh, Amir Nima Fatahian, Omid M T Rouzbehani, Marissa A Hathaway, Tariq Mosleh, Vishaka Vinod, Sidney Vowles, Sophie L Stephens, Siu-Lai Desmond Chung, Isaac D Cao, Anila Jonnavithula, J David Symons, Sihem Boudina
Cardiovasc Res. 2024 Apr; 120(5): 531–547. Published online 2024 Feb 9. doi: 10.1093/cvr/cvae023
PMCID:
PMC11060490
AbstractArticlePDF–1.6M
14.
Mitochondrial dysfunction induced by HIF‐1α under hypoxia contributes to the development of gastric mucosal lesions
Yuelin Xiao, Xianzhi Liu, Kaiduan Xie, Jiajie Luo, Yiwang Zhang, Xiaoli Huang, Jinni Luo, Siwei Tan
Clin Transl Med. 2024 Apr; 14(4): e1653. Published online 2024 Apr 15. doi: 10.1002/ctm2.1653
PMCID:
PMC11016940
AbstractArticlePDF–8.7M
15.
Single-embryo transcriptomic atlas of oxygen response reveals the critical role of HIF-1α in prompting embryonic zygotic genome activation
Fusheng Yao, Meiqiang Chu, Guangyin Xi, Jiage Dai, Zhaochen Wang, Jia Hao, Qianying Yang, Wenjing Wang, Yawen Tang, Jingyu Zhang, Yuan Yue, Yue Wang, Yefen Xu, Wei Zhao, Lizhu Ma, Juan Liu, Zhenni Zhang, Jianhui Tian, Lei An
Redox Biol. 2024 Jun; 72: 103147. Published online 2024 Apr 2. doi: 10.1016/j.redox.2024.103147
PMCID:
PMC11016760
AbstractArticlePDF–13M
16.
Granulocytic myeloid-derived suppressor cell activity during biofilm infection is regulated by a glycolysis/HIF1a axis
Christopher M. Horn, Prabhakar Arumugam, Zachary Van Roy, Cortney E. Heim, Rachel W. Fallet, Blake P. Bertrand, Dhananjay Shinde, Vinai C. Thomas, Svetlana G. Romanova, Tatiana K. Bronich, Curtis W. Hartman, Kevin L. Garvin, Tammy Kielian
J Clin Invest. 2024 Apr 15; 134(8): e174051. Published online 2024 Feb 29. doi: 10.1172/JCI174051
PMCID:
PMC11014666
AbstractArticlePDF–3.9M
17.
A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis
Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina
J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787
PMCID:
PMC11014657
AbstractArticlePDF–16M
18.
Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin
Uttkarsh Ayyangar, Aneesh Karkhanis, Heather Tay, Aliya Farissa Binte Afandi, Oindrila Bhattacharjee, Lalitha KS, Sze Han Lee, James Chan, Srikala Raghavan
EMBO J. 2024 Apr; 43(7): 1113–1134. Published online 2024 Feb 28. doi: 10.1038/s44318-024-00039-y
PMCID:
PMC10987662
AbstractArticlePDF–12M
19.
Hypoxia inducible factor-1α regulates microglial innate immune memory and the pathology of Parkinson’s disease
Hongtian Dong, Xiaoshuang Zhang, Yufei Duan, Yongtao He, Jiayin Zhao, Zishan Wang, Jinghui Wang, Qing Li, Guangchun Fan, Zhaolin Liu, Chenye Shen, Yunhe Zhang, Mei Yu, Jian Fei, Fang Huang
J Neuroinflammation. 2024; 21: 80. Published online 2024 Mar 30. doi: 10.1186/s12974-024-03070-2
PMCID:
PMC10981320
AbstractArticlePDF–6.4M
20.
The DUX4–HIF1α Axis in Murine and Human Muscle Cells: A Link More Complex Than Expected
Thuy-Hang Nguyen, Maelle Limpens, Sihame Bouhmidi, Lise Paprzycki, Alexandre Legrand, Anne-Emilie Declèves, Philipp Heher, Alexandra Belayew, Christopher R. S. Banerji, Peter S. Zammit, Alexandra Tassin
Int J Mol Sci. 2024 Mar; 25(6): 3327. Published online 2024 Mar 15. doi: 10.3390/ijms25063327
PMCID:
PMC10969790
AbstractArticlePDF–8.2M

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