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Items: 1 to 20 of 25

1.
Development and External Validation of a Novel Immune Checkpoint–Related Gene Signature for Prediction of Overall Survival in Hepatocellular Carcinoma
Enfa Zhao, Shimin Chen, Ying Dang
Front Mol Biosci. 2020; 7: 620765. Published online 2021 Jan 21. doi: 10.3389/fmolb.2020.620765
PMCID:
PMC7859359
AbstractArticlePDF–4.0M
2.
MEK drives BRAF activation through allosteric control of KSR proteins
Hugo Lavoie, Malha Sahmi, Pierre Maisonneuve, Sara A. Marullo, Neroshan Thevakumaran, Ting Jin, Igor Kurinov, Frank Sicheri, Marc Therrien
Nature. Author manuscript; available in PMC 2019 Mar 25.
Published in final edited form as: Nature. 2018 Feb 22; 554(7693): 549–553. Published online 2018 Feb 12. doi: 10.1038/nature25478
PMCID:
PMC6433120
AbstractArticlePDF–2.4M
3.
MiR‐339 inhibits proliferation of pulmonary artery smooth muscle cell by targeting FGF signaling
Jidong Chen, Xiaolei Cui, Li Li, Junle Qu, J. Usha Raj, Deming Gou
Physiol Rep. 2017 Sep; 5(18): e13441. Published online 2017 Sep 26. doi: 10.14814/phy2.13441
PMCID:
PMC5617928
AbstractArticlePDF–1.6M
4.
MEK2 is a prognostic marker and potential chemo-sensitizing target for glioma patients undergoing temozolomide treatment
Hua He, Maojin Yao, Wenhao Zhang, Bangbao Tao, Feili Liu, Shu Li, Yan Dong, Chenran Zhang, Yicheng Meng, Yuxin Li, Guohan Hu, Chun Luo, Hui Zong, Yicheng Lu
Cell Mol Immunol. 2016 Sep; 13(5): 658–668. Published online 2015 Jul 20. doi: 10.1038/cmi.2015.46
PMCID:
PMC5037281
AbstractArticlePDF–2.7M
5.
c-Raf, but not B-Raf, is essential for development of K-Ras oncogene driven non-small cell lung carcinoma
Rafael B. Blasco, Sarah Francoz, David Santamaría, Marta Cañamero, Pierre Dubus, Jean Charron, Manuela Baccarini, Mariano Barbacid
Cancer Cell. Author manuscript; available in PMC 2016 May 3.
Published in final edited form as: Cancer Cell. 2011 May 17; 19(5): 652–663. Published online 2011 Apr 21. doi: 10.1016/j.ccr.2011.04.002
PMCID:
PMC4854330
AbstractArticlePDF–2.6M
6.
Molecular and functional analysis of a novel MEK2 mutation in cardio-facio-cutaneous syndrome: Transmission through four generations
Katherine A. Rauen, William E. Tidyman, Anne L. Estep, Srirangan Sampath, Henry M. Peltier, Sherri J. Bale, Yves Lacassie
Am J Med Genet A. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: Am J Med Genet A. 2010 Apr; 0(4): 807–814. doi: 10.1002/ajmg.a.33342
PMCID:
PMC4180666
AbstractArticlePDF–633K
7.
B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS
Kevin J. O’Donovan, Kaijie Ma, Hengchang Guo, Chen Wang, Fang Sun, Seung Baek Han, Hyukmin Kim, Jamie K. Wong, Jean Charron, Hongyan Zou, Young-Jin Son, Zhigang He, Jian Zhong
J Exp Med. 2014 May 5; 211(5): 801–814. doi: 10.1084/jem.20131780
PMCID:
PMC4010899
AbstractArticlePDF–4.1M
8.
Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome
Silvia Remeseiro, Ana Cuadrado, Shimako Kawauchi, Anne L. Calof, Arthur D. Lander, Ana Losada
Biochim Biophys Acta. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Biochim Biophys Acta. 2013 Dec; 1832(12): 10.1016/j.bbadis.2013.07.020. Published online 2013 Aug 3. doi: 10.1016/j.bbadis.2013.07.020
PMCID:
PMC3825806
AbstractArticlePDF–912K
9.
Anthrax Lethal Toxin Downregulates Claudin-5 Expression in Human Endothelial Tight Junctions
Felice D’Agnillo, Matthew C. Williams, Mahtab Moayeri, Jason M. Warfel
PLoS One. 2013; 8(4): e62576. Published online 2013 Apr 23. doi: 10.1371/journal.pone.0062576
PMCID:
PMC3633853
AbstractArticlePDF–7.3M
10.
Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis
Chan-Hyun Na, Drew R. Jones, Yanling Yang, Xusheng Wang, Yanji Xu, Junmin Peng
J Proteome Res. Author manuscript; available in PMC 2013 Sep 7.
Published in final edited form as: J Proteome Res. 2012 Sep 7; 11(9): 4722–4732. Published online 2012 Aug 15. doi: 10.1021/pr300536k
PMCID:
PMC3443409
AbstractArticlePDF–4.2M
11.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
12.
Phosphoinositide 3-Kinase-Dependent Inhibition of Dendritic Cell Interleukin-12 Production by Giardia lamblia
Joel Désiré Kamda, Steven M. Singer
Infect Immun. 2009 Feb; 77(2): 685–693. Published online 2008 Dec 1. doi: 10.1128/IAI.00718-08
PMCID:
PMC2632045
AbstractArticlePDF–657K
13.
Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors
Laure Voisin, Catherine Julien, Stéphanie Duhamel, Kailesh Gopalbhai, Isabelle Claveau, Marc K Saba-El-Leil, Ian Gaël Rodrigue-Gervais, Louis Gaboury, Daniel Lamarre, Mark Basik, Sylvain Meloche
BMC Cancer. 2008; 8: 337. Published online 2008 Nov 17. doi: 10.1186/1471-2407-8-337
PMCID:
PMC2596176
AbstractArticlePDF–3.6M
14.
Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development
Jason Newbern, Jian Zhong, Rasika S. Wickramasinghe, Xiaoyan Li, Yaohong Wu, Ivy Samuels, Natalie Cherosky, J. Colleen Karlo, Brianne O'Loughlin, Jamie Wikenheiser, Madhusudhana Gargesha, Yong Qiu Doughman, Jean Charron, David D. Ginty, Michiko Watanabe, Sulagna C. Saitta, William D. Snider, Gary E. Landreth
Proc Natl Acad Sci U S A. 2008 Nov 4; 105(44): 17115–17120. Published online 2008 Oct 24. doi: 10.1073/pnas.0805239105
PMCID:
PMC2579387
AbstractArticlePDF–1.8M
15.
Enhanced expressions of microvascular smooth muscle receptors after focal cerebral ischemia occur via the MAPK MEK/ERK pathway
Aida Maddahi, Lars Edvinsson
BMC Neurosci. 2008; 9: 85. Published online 2008 Sep 15. doi: 10.1186/1471-2202-9-85
PMCID:
PMC2553085
AbstractArticlePDF–3.9M
16.
Mutation Analysis of BRAF, MEK1 and MEK2 in 15 Ovarian Cancer Cell Lines: Implications for Therapy
Anne L. Estep, Chana Palmer, Frank McCormick, Katherine A. Rauen
PLoS One. 2007; 2(12): e1279. Published online 2007 Dec 5. doi: 10.1371/journal.pone.0001279
PMCID:
PMC2093994
AbstractArticlePDF–184K
17.
Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation
Melinda D Willard, Francis S Willard, Xiaoyan Li, Steven D Cappell, William D Snider, David P Siderovski
EMBO J. 2007 Apr 18; 26(8): 2029–2040. Published online 2007 Mar 22. doi: 10.1038/sj.emboj.7601659
PMCID:
PMC1852785
AbstractArticlePDF–392K
18.
Mitogen-activated protein kinase translocates to the nucleus during ischaemia and is activated during reperfusion.
Y Mizukami, K i Yoshida
Biochem J. 1997 May 1; 323(Pt 3): 785–790. doi: 10.1042/bj3230785
PMCID:
PMC1218383
SummaryPDF–434K
19.
Renaturation and partial peptide sequencing of mitogen-activated protein kinase (MAP kinase) activator from rabbit skeletal muscle.
J Wu, H Michel, A Rossomando, T Haystead, J Shabanowitz, D F Hunt, T W Sturgill
Biochem J. 1992 Aug 1; 285(Pt 3): 701–705. doi: 10.1042/bj2850701
PMCID:
PMC1132850
SummaryPage BrowsePDF–1.1M
20.
zeta PKC induces phosphorylation and inactivation of I kappa B-alpha in vitro.
M T Diaz-Meco, I Dominguez, L Sanz, P Dent, J Lozano, M M Municio, E Berra, R T Hay, T W Sturgill, J Moscat
EMBO J. 1994 Jun 15; 13(12): 2842–2848. doi: 10.1002/j.1460-2075.1994.tb06578.x
PMCID:
PMC395165
SummaryPage BrowsePDF–1.6M

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