PMC Links for GEO Profiles (Select 24847888) - PMC

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Items: 13

Select item 106563271.

Mutant p53^R211* ameliorates inflammatory arthritis in AIA rats via inhibition of TBK1-IRF3 innate immune response

Yaling Zeng, Jerome P. L. Ng, Linna Wang, Xiongfei Xu, Betty Yuen Kwan Law, Guobing Chen, Hang Hong Lo, Lijun Yang, Jiujie Yang, Lei Zhang, Liqun Qu, Xiaoyun Yun, Jing Zhong, Ruihong Chen, Dingqi Zhang, Yuping Wang, Weidan Luo, Congling Qiu, Baixiong Huang, Wenfeng liu, Liang Liu, Vincent Kam Wai Wong

Inflamm Res. 2023; 72(12): 2199–2219. Published online 2023 Nov 8. doi: 10.1007/s00011-023-01809-w

PMCID:: PMC10656327

Abstract Article PDF–13M

Select item 76539192.

TBK1 regulates regeneration of pancreatic β-cells

Yun-Fang Jia, Subbiah Jeeva, Jin Xu, Carrie Jo Heppelmann, Jin Sung Jang, Michael Q. Slama, Subhasish Tapadar, Adegboyega K. Oyelere, Sang-Moo Kang, Aleksey V. Matveyenko, Quinn P. Peterson, Chong Hyun Shin

Sci Rep. 2020; 10: 19374. Published online 2020 Nov 9. doi: 10.1038/s41598-020-76600-6

PMCID:: PMC7653919

Abstract Article PDF–5.2M

Select item 74594103.

TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models

Ramanath Narayana Hegde, Anass Chiki, Lara Petricca, Paola Martufi, Nicolas Arbez, Laurent Mouchiroud, Johan Auwerx, Christian Landles, Gillian P Bates, Malvindar K Singh‐Bains, Mike Dragunow, Maurice A Curtis, Richard LM Faull, Christopher A Ross, Andrea Caricasole, Hilal A Lashuel

EMBO J. 2020 Sep 1; 39(17): e104671. Published online 2020 Aug 5. doi: 10.15252/embj.2020104671

PMCID:: PMC7459410

Abstract Article PDF–3.0M

Select item 52784634.

Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism

Maroof Hasan, Vijay K. Gonugunta, Nicole Dobbs, Aktar Ali, Guillermo Palchik, Maria A. Calvaruso, Ralph J. DeBerardinis, Nan Yan

Proc Natl Acad Sci U S A. 2017 Jan 24; 114(4): 746–751. Published online 2017 Jan 9. doi: 10.1073/pnas.1611113114

PMCID:: PMC5278463

Abstract Article PDF–1.3M

Select item 49332345.

The Type I Interferon-IRF7 Axis Mediates Transcriptional Expression of Usp25 Gene

Yujie Ren, Yin Zhao, Dandan Lin, Ximing Xu, Qiyun Zhu, Jing Yao, Hong-Bing Shu, Bo Zhong

J Biol Chem. 2016 Jun 17; 291(25): 13206–13215. Published online 2016 Apr 27. doi: 10.1074/jbc.M116.718080

PMCID:: PMC4933234

Abstract Article PDF–3.7M

Select item 49105336.

Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin‐2 to induce motor neuron dysfunction and cell death

Chantal Sellier, Maria‐Letizia Campanari, Camille Julie Corbier, Angeline Gaucherot, Isabelle Kolb‐Cheynel, Mustapha Oulad‐Abdelghani, Frank Ruffenach, Adeline Page, Sorana Ciura, Edor Kabashi, Nicolas Charlet‐Berguerand

EMBO J. 2016 Jun 15; 35(12): 1276–1297. Published online 2016 Apr 21. doi: 10.15252/embj.201593350

PMCID:: PMC4910533

Abstract Article PDF–1.5M

Select item 37145387.

Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth

Philipp Wild, Hesso Farhan, David G. McEwan, Sebastian Wagner, Vladimir V. Rogov, Nathan R. Brady, Benjamin Richter, Jelena Korac, Oliver Waidmann, Chunaram Choudhary, Volker Dötsch, Dirk Bumann, Ivan Dikic

Science. Author manuscript; available in PMC 2013 Jul 18.

Published in final edited form as: Science. 2011 Jul 8; 333(6039): 228–233. Published online 2011 May 26. doi: 10.1126/science.1205405

PMCID:: PMC3714538

Abstract Article PDF–2.5M

Select item 37026318.

Structural Insights into the Functions of TBK1 in Innate Antimicrobial Immunity

Chang Shu, Banumathi Sankaran, Catherine T. Chaton, Andrew B. Herr, Ashutosh Mishra, Junmin Peng, Pingwei Li

Structure. Author manuscript; available in PMC 2014 Jul 2.

Published in final edited form as: Structure. 2013 Jul 2; 21(7): 1137–1148. Published online 2013 Jun 6. doi: 10.1016/j.str.2013.04.025

PMCID:: PMC3702631

Abstract Article PDF–4.3M

Select item 35227729.

Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes

Maroof Hasan, James Koch, Dinesh Rakheja, Asit K. Pattnaik, James Brugarolas, Igor Dozmorov, Beth Levine, Edward K. Wakeland, Min Ae Lee-kirsch, Nan Yan

Nat Immunol. Author manuscript; available in PMC 2013 Jul 1.

Published in final edited form as: Nat Immunol. 2013 Jan; 14(1): 61–71. Published online 2012 Nov 18. doi: 10.1038/ni.2475