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Select item 114871851.

SUMOylation of Warts kinase promotes neural stem cell reactivation

Yang Gao, Ye Sing Tan, Jiaen Lin, Liang Yuh Chew, Htet Yamin Aung, Brinda Palliyana, Mahekta R. Gujar, Kun-Yang Lin, Shu Kondo, Hongyan Wang

Nat Commun. 2024; 15: 8557. Published online 2024 Oct 17. doi: 10.1038/s41467-024-52569-y

PMCID:: PMC11487185

Abstract Article PDF–5.9M

Select item 113308662.

Ribosome stalling during c-myc translation presents actionable cancer cell vulnerability

Tejinder Pal Khaket, Suman Rimal, Xingjun Wang, Sunil Bhurtel, Yen-Chi Wu, Bingwei Lu

PNAS Nexus. 2024 Aug; 3(8): pgae321. Published online 2024 Aug 13. doi: 10.1093/pnasnexus/pgae321

Correction in:: PNAS Nexus. 2024 Nov; 3(11): pgae478.

PMCID:: PMC11330866

Abstract Article PDF–1015K

Select item 112684183.

Astrocytes control quiescent NSC reactivation via GPCR signaling–mediated F-actin remodeling

Kun-Yang Lin, Mahekta R. Gujar, Jiaen Lin, Wei Yung Ding, Jiawen Huang, Yang Gao, Ye Sing Tan, Xiang Teng, Low Siok Lan Christine, Pakorn Kanchanawong, Yusuke Toyama, Hongyan Wang

Sci Adv. 2024 Jul 26; 10(30): eadl4694. Published online 2024 Jul 24. doi: 10.1126/sciadv.adl4694

PMCID:: PMC11268418

Abstract Article PDF–19M

Select item 112294224.

Mitf, with Yki and STRIPAK-PP2A, is a key determinant of form and fate in the progenitor epithelium of the Drosophila eye

Tianyi Zhang, Qingxiang Zhou, Nisveta Jusić, Wenwen Lu, Francesca Pignoni, Scott J. Neal

Eur J Cell Biol. Author manuscript; available in PMC 2024 Jul 8.

Published in final edited form as: Eur J Cell Biol. 2024 Jun; 103(2): 151421. Published online 2024 May 15. doi: 10.1016/j.ejcb.2024.151421

PMCID:: PMC11229422

Abstract Article PDF–1.7M

Select item 111133415.

Expanding the roles of chromatin insulators in nuclear architecture, chromatin organization and genome function

Todd Schoborg, Mariano Labrador

Cell Mol Life Sci. 2014 Nov; 71(21): 4089–4113. Published online 2014 Jul 11. doi: 10.1007/s00018-014-1672-6

PMCID:: PMC11113341

Abstract Article PDF–887K

Select item 111057956.

Regulation of the Hippo pathway in cancer biology

Sungho Moon, So Yeon Park, Hyun Woo Park

Cell Mol Life Sci. 2018 Jul; 75(13): 2303–2319. Published online 2018 Mar 30. doi: 10.1007/s00018-018-2804-1

PMCID:: PMC11105795

Abstract Article PDF–2.3M

Select item 110743277.

The AAA-ATPase Ter94 regulates wing size in Drosophila by suppressing the Hippo pathway

Mingming Li, Wenhao Ding, Yanran Deng, Yunhe Zhao, Qingxin Liu, Zizhang Zhou

Commun Biol. 2024; 7: 533. Published online 2024 May 6. doi: 10.1038/s42003-024-06246-x

PMCID:: PMC11074327

Abstract Article PDF–10M

Select item 109112798.

The Drosophila tumour suppressor Lgl and Vap33 activate the Hippo pathway through a dual mechanism

Marta Portela, Swastik Mukherjee, Sayantanee Paul, John E. La Marca, Linda M. Parsons, Alexey Veraksa, Helena E. Richardson

J Cell Sci. 2024 Feb 15; 137(4): jcs261917. Published online 2024 Feb 16. doi: 10.1242/jcs.261917

PMCID:: PMC10911279

Abstract Article

Select item 108552979.

Connecting Hippo Pathway and Cytoophidia in Drosophila Posterior Follicle Cells

Rui-Yu Weng, Lei Zhang, Ji-Long Liu

Int J Mol Sci. 2024 Feb; 25(3): 1453. Published online 2024 Jan 25. doi: 10.3390/ijms25031453

PMCID:: PMC10855297

Abstract Article PDF–25M

Select item 1084263310.

Combined inactivation of RB and Hippo converts differentiating Drosophila photoreceptors into eye progenitor cells through derepression of homothorax

Alexandra E. Rader, Battuya Bayarmagnai, Maxim V. Frolov

Dev Cell. Author manuscript; available in PMC 2024 Nov 6.

Published in final edited form as: Dev Cell. 2023 Nov 6; 58(21): 2261–2274.e6. Published online 2023 Oct 16. doi: 10.1016/j.devcel.2023.09.003

PMCID:: PMC10842633

Abstract Article PDF–3.7M

Select item 1065111011.

KDM5-mediated activation of genes required for mitochondrial biology is necessary for viability in Drosophila

Michael F. Rogers, Owen J. Marshall, Julie Secombe

Development. 2023 Nov 1; 150(21): dev202024. Published online 2023 Nov 6. doi: 10.1242/dev.202024

PMCID:: PMC10651110

Abstract Article

Select item 1061405812.

Protein Phosphatase 2A with B′ specificity subunits regulates the Hippo-Yorkie signaling axis in the Drosophila eye disc

Scott J. Neal, Qingxiang Zhou, Francesca Pignoni

J Cell Sci. 2022 Oct 15; 135(20): jcs259558. Published online 2022 Oct 25. doi: 10.1242/jcs.259558

PMCID:: PMC10614058

Abstract Article

Select item 1058821813.

Modelling TDP-43 proteinopathy in Drosophila uncovers shared and neuron-specific targets across ALS and FTD relevant circuits

R. Keating Godfrey, Eric Alsop, Reed T. Bjork, Brijesh S. Chauhan, Hillary C. Ruvalcaba, Jerry Antone, Lauren M. Gittings, Allison F. Michael, Christi Williams, Grace Hala’ufia, Alexander D. Blythe, Megan Hall, Rita Sattler, Kendall Van Keuren-Jensen, Daniela C. Zarnescu

Acta Neuropathol Commun. 2023; 11: 168. Published online 2023 Oct 20. doi: 10.1186/s40478-023-01656-0

PMCID:: PMC10588218

Abstract Article PDF–30M

Select item 1057177514.

The Interaction of Mechanics and the Hippo Pathway in Drosophila melanogaster

Jia Gou, Tianhao Zhang, Hans G. Othmer

Cancers (Basel) 2023 Oct; 15(19): 4840. Published online 2023 Oct 3. doi: 10.3390/cancers15194840

PMCID:: PMC10571775

Abstract Article PDF–7.3M

Select item 1049758015.

E2 enzyme Bruce negatively regulates Hippo signaling through POSH-mediated expanded degradation

Sha Song, Xianjue Ma

Cell Death Dis. 2023 Sep; 14(9): 602. Published online 2023 Sep 12. doi: 10.1038/s41419-023-06130-2

PMCID:: PMC10497580

Abstract Article PDF–4.9M

Select item 1037046416.

Hippo pathway: Regulation, Deregulation and Potential Therapeutic Targets in Cancer

Suman Mohajan, Praveen Kumar Jaiswal, Mousa Vatanmakarian, Hassan Yousefi, Saikolappan Sankaralingam, Suresh K. Alahari, Sweaty Koul, Hari K Koul

Cancer Lett. Author manuscript; available in PMC 2023 Jul 26.

Published in final edited form as: Cancer Lett. 2021 Jun 1; 507: 112–123. Published online 2021 Mar 15. doi: 10.1016/j.canlet.2021.03.006

PMCID:: PMC10370464

Abstract Article PDF–1.3M

Select item 1027883217.

Activation of Hippo Pathway Damages Slit Diaphragm by Deprivation of Ajuba Proteins

Kevin Gilhaus, Claudia Cepok, David Kamm, Beate Surmann, Pavel I. Nedvetsky, Jana Emich, Alina Sundukova, Katharina Saatkamp, Harald Nüsse, Jürgen Klingauf, Dirk O. Wennmann, Britta George, Michael P. Krahn, Hermann-Joseph Pavenstädt, Beate A. Vollenbröker

J Am Soc Nephrol. 2023 Jun; 34(6): 1039–1055. Published online 2023 Mar 16. doi: 10.1681/ASN.0000000000000107

PMCID:: PMC10278832

Abstract Article

Select item 1027549418.

The role of Hippo pathway in ovarian development

Mengdi Zhu, Menghao Xu, Jinmin Zhang, Cuihong Zheng

Front Physiol. 2023; 14: 1198873. Published online 2023 Jun 2. doi: 10.3389/fphys.2023.1198873

PMCID:: PMC10275494

Abstract Article PDF–1.6M

Select item 1012204619.

Coordination of tissue homeostasis and growth by the Scribble-α-Catenin-Septate junction complex

Yunxian Huang, Jinghua Gui, Satu-Marja Myllymäki, Marja L. Mikkola, Osamu Shimmi

iScience. 2023 Apr 21; 26(4): 106490. Published online 2023 Mar 22. doi: 10.1016/j.isci.2023.106490

PMCID:: PMC10122046

Abstract Article PDF–7.2M

Select item 1010456620.

Tctp, a unique Ing5-binding partner, inhibits the chromatin binding of Enok in Drosophila

Lee-Hyang Kim, Ja-Young Kim, Yu-Ying Xu, Mi Ae Lim, Bon Seok Koo, Jung Hae Kim, Sung-Eun Yoon, Young-Joon Kim, Kwang-Wook Choi, Jae Won Chang, Sung-Tae Hong

Proc Natl Acad Sci U S A. 2023 Apr 11; 120(15): e2218361120. Published online 2023 Apr 4. doi: 10.1073/pnas.2218361120