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Items: 1 to 20 of 284

1.
Interleukin-4 predicts the efficacy of an anti-oxycodone vaccine and alters vaccine-specific antibody secreting cell proliferation in mice
Bethany Crouse, Carly Baehr, Dustin Hicks, Marco Pravetoni
J Immunol. Author manuscript; available in PMC 2024 Aug 13.
Published in final edited form as: J Immunol. 2023 May 1; 210(9): 1272–1280. doi: 10.4049/jimmunol.2200605
PMCID:
PMC11321710
AbstractArticlePDF–837K
2.
A type 2 immune circuit in the stomach controls mammalian adaptation to dietary chitin
Do-Hyun Kim, Yilin Wang, Haerin Jung, Rachael L. Field, Xinya Zhang, Ta-Chiang Liu, Changqing Ma, James S. Fraser, Jonathan R. Brestoff, Steven J. Van Dyken
Science. Author manuscript; available in PMC 2024 Feb 14.
Published in final edited form as: Science. 2023 Sep 8; 381(6662): 1092–1098. Published online 2023 Sep 7. doi: 10.1126/science.add5649
PMCID:
PMC10865997
AbstractArticlePDF–957K
3.
Immune sensing of food allergens promotes avoidance behaviour
Esther B. Florsheim, Nathaniel D. Bachtel, Jaime L. Cullen, Bruna G. C. Lima, Mahdieh Godazgar, Fernando Carvalho, Carolina P. Chatain, Marcelo R. Zimmer, Cuiling Zhang, Gregory Gautier, Pierre Launay, Andrew Wang, Marcelo O. Dietrich, Ruslan Medzhitov
Nature. 2023; 620(7974): 643–650. Published online 2023 Jul 12. doi: 10.1038/s41586-023-06362-4
PMCID:
PMC10432274
AbstractArticlePDF–7.0M
4.
Competition between skin antimicrobial peptides and commensal bacteria in type 2 inflammation enables survival of S. aureus
Teruaki Nakatsuji, Samantha L. Brinton, Kellen J. Cavagnero, Alan M. O’Neill, Yang Chen, Tatsuya Dokoshi, Anna M. Butcher, Olive C. Osuoji, Faiza Shafiq, Josh L. Espinoza, Christopher L. Dupont, Tissa R. Hata, Richard L. Gallo
Cell Rep. Author manuscript; available in PMC 2023 Jun 28.
Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112494. Published online 2023 May 10. doi: 10.1016/j.celrep.2023.112494
PMCID:
PMC10303920
AbstractArticlePDF–2.5M
5.
The IL-4Rα Q576R polymorphism is associated with increased severity of atopic dermatitis and exaggerates allergic skin inflammation in mice
Barbara Yang, Hazel Wilkie, Mrinmoy Das, Maheshwor Timilshina, Wayne Bainter, Brian Woods, Michelle Daya, Meher P. Boorgula, Rasika A. Mathias, Peggy Lai, Carter R. Petty, Edie Weller, Hani Harb, Talal A. Chatila, Donald Y. M. Leung, Lisa A. Beck, Eric L. Simpson, Tissa R. Hata, Kathleen C. Barnes, Wanda Phipatanakul, Juan-Manuel Leyva-Castillo, Raif S Geha
J Allergy Clin Immunol. Author manuscript; available in PMC 2024 May 1.
Published in final edited form as: J Allergy Clin Immunol. 2023 May; 151(5): 1296–1306.e7. Published online 2023 Jan 21. doi: 10.1016/j.jaci.2023.01.011
PMCID:
PMC10164706
AbstractArticlePDF–1.4M
6.
The Role of IL-13 and IL-4 in Adipose Tissue Fibrosis
Lilli Arndt, Andreas Lindhorst, Julia Neugebauer, Anne Hoffmann, Constance Hobusch, Vasileia-Ismini Alexaki, Adhideb Ghosh, Matthias Blüher, Christian Wolfrum, Markus Glaß, Martin Gericke
Int J Mol Sci. 2023 Mar; 24(6): 5672. Published online 2023 Mar 16. doi: 10.3390/ijms24065672
PMCID:
PMC10051142
AbstractArticlePDF–2.6M
7.
IL-4Rα signalling in B cells and T cells play differential roles in acute and chronic atopic dermatitis
Martyna Scibiorek, Nontobeko Mthembu, Sandisiwe Mangali, Amkele Ngomti, Paul Ikwegbue, Frank Brombacher, Sabelo Hadebe
Sci Rep. 2023; 13: 144. Published online 2023 Jan 4. doi: 10.1038/s41598-022-26637-6
Correction in:
Sci Rep. 2023; 13: 9651.
PMCID:
PMC9812985
AbstractArticlePDF–1.6M
8.
A Common IL-4 Receptor Variant Promotes Asthma Severity via a Treg Cell GRB2-IL-6-Notch4 Circuit
Mehdi Benamar, Hani Harb, Qian Chen, Muyun Wang, Tsz Man Fion Chan, Jason Fong, Wanda Phipatanakul, Amparito Cunningham, Deniz Ertem, Carter R. Petty, Amirhosein J. Mousavi, Constantinos Sioutas, Elena Crestani, Talal A. Chatila
Allergy. Author manuscript; available in PMC 2023 Nov 1.
Published in final edited form as: Allergy. 2022 Nov; 77(11): 3377–3387. Published online 2022 Jul 25. doi: 10.1111/all.15444
PMCID:
PMC9617759
AbstractArticlePDF–2.0M
9.
Innate type 2 immunity controls hair follicle commensalism by Demodex mites
Roberto R. Ricardo-Gonzalez, Maya E. Kotas, Claire E. O’Leary, Katelyn Singh, William Damsky, Chang Liao, Elizabeth Arouge, Iliana Tenvooren, Diana M. Marquez, Andrew W. Schroeder, Jarish N. Cohen, Marlys S. Fassett, Jinwoo Lee, Scott G. Daniel, Kyle Bittinger, Roberto Efraín Díaz, James S. Fraser, Niwa Ali, K. Mark Ansel, Matthew H. Spitzer, Hong-Erh Liang, Richard M. Locksley
Immunity. Author manuscript; available in PMC 2023 Oct 11.
Published in final edited form as: Immunity. 2022 Oct 11; 55(10): 1891–1908.e12. Published online 2022 Aug 30. doi: 10.1016/j.immuni.2022.08.001
PMCID:
PMC9561030
AbstractArticlePDF–2.1M
10.
Interleukin‐4 receptor alpha signaling regulates monocyte homeostasis
Patrick Haider, Julia B. Kral‐Pointner, Manuel Salzmann, Florian Moik, Sonja Bleichert, Waltraud C. Schrottmaier, Christoph Kaun, Mira Brekalo, Michael B. Fischer, Walter S. Speidl, Christian Hengstenberg, Bruno K. Podesser, Kurt Huber, Ingrid Pabinger, Sylvia Knapp, Frank Brombacher, Christine Brostjan, Cihan Ay, Johann Wojta, Philipp J. Hohensinner
FASEB J. 2022 Oct; 36(10): e22532. Published online 2022 Sep 5. doi: 10.1096/fj.202101672RR
PMCID:
PMC9544925
AbstractArticlePDF–32M
11.
Interleukin 4 Controls the Pro-Tumoral Role of Macrophages in Mammary Cancer Pulmonary Metastasis in Mice
Carolina Rodriguez-Tirado, David Entenberg, Jiufeng Li, Bin-Zhi Qian, John S. Condeelis, Jeffrey W. Pollard
Cancers (Basel) 2022 Sep; 14(17): 4336. Published online 2022 Sep 5. doi: 10.3390/cancers14174336
PMCID:
PMC9454655
AbstractArticlePDF–7.8M
12.
Protection against influenza-induced Acute Lung Injury (ALI) by enhanced induction of M2a macrophages: possible role of PPARγ/RXR ligands in IL-4-induced M2a macrophage differentiation
Archana Gopalakrishnan, John Joseph, Kari Ann Shirey, Achsah D. Keegan, Marina S. Boukhvalova, Stefanie N. Vogel, Jorge C. G. Blanco
Front Immunol. 2022; 13: 968336. Published online 2022 Aug 16. doi: 10.3389/fimmu.2022.968336
PMCID:
PMC9424652
AbstractArticlePDF–5.6M
13.
B Cells Produce the Tissue-Protective Protein RELMα during Helminth Infection, which Inhibits IL-17 Expression and Limits Emphysema
Fei Chen, Wenhui Wu, Lianhua Jin, Ariel Millman, Mark Palma, Darine W. El-Naccache, Katherine E. Lothstein, Chen Dong, Karen L. Edelblum, William C. Gause
Cell Rep. Author manuscript; available in PMC 2022 Aug 26.
Published in final edited form as: Cell Rep. 2018 Dec 4; 25(10): 2775–2783.e3. doi: 10.1016/j.celrep.2018.11.038
PMCID:
PMC9413029
AbstractArticlePDF–2.3M
14.
M2 Macrophages promote IL-33 expression, ILC2 expansion and mucous metaplasia in response to early life rhinovirus infections
Mingyuan Han, Haley A. Breckenridge, Shiuhyang Kuo, Shilpi Singh, Adam G. Goldsmith, Yiran Li, Jordan E. Kreger, J. Kelley Bentley, Marc B. Hershenson
Front Immunol. 2022; 13: 952509. Published online 2022 Aug 12. doi: 10.3389/fimmu.2022.952509
PMCID:
PMC9412168
AbstractArticlePDF–10M
15.
Helminth resistance is mediated by differential activation of recruited monocyte-derived alveolar macrophages and arginine depletion
Fei Chen, Darine W. El-Naccache, John J. Ponessa, Alexander Lemenze, Vanessa Espinosa, Wenhui Wu, Katherine Lothstein, Linhua Jin, Olivia Antao, Jason S. Weinstein, Payal Damani-Yokota, Kamal Khanna, Peter J. Murray, Amariliz Rivera, Mark C. Siracusa, William C. Gause
Cell Rep. Author manuscript; available in PMC 2022 Aug 25.
Published in final edited form as: Cell Rep. 2022 Jan 11; 38(2): 110215. doi: 10.1016/j.celrep.2021.110215
PMCID:
PMC9403845
AbstractArticlePDF–1.5M
16.
Targeting interleukin 4 receptor alpha on tumor-associated macrophages reduces the pro-tumor macrophage phenotype
Amber E. de Groot, Kayla V. Myers, Timothy E.G. Krueger, W. Nathaniel Brennen, Sarah R. Amend, Kenneth J. Pienta
Neoplasia. 2022 Oct; 32: 100830. Published online 2022 Aug 5. doi: 10.1016/j.neo.2022.100830
PMCID:
PMC9386102
AbstractArticlePDF–2.7M
17.
CD4+ T helper 2 cells suppress breast cancer by inducing terminal differentiation
Margherita Boieri, Anna Malishkevich, Ranya Guennoun, Emanuela Marchese, Sanne Kroon, Kathryn E. Trerice, Mary Awad, Jong Ho Park, Sowmya Iyer, Johannes Kreuzer, Wilhelm Haas, Miguel N. Rivera, Shadmehr Demehri
J Exp Med. 2022 Jul 4; 219(7): e20201963. Published online 2022 Jun 3. doi: 10.1084/jem.20201963
PMCID:
PMC9170526
AbstractArticlePDF–9.3M
18.
Bile acid-sensitive tuft cells regulate biliary neutrophil influx
Claire E. O’Leary, Julia Sbierski-Kind, Maya E. Kotas, Johanna C. Wagner, Hong-Erh Liang, Andrew W. Schroeder, Jeshua C. de Tenorio, Jakob von Moltke, Roberto R. Ricardo-Gonzalez, Walter L. Eckalbar, Ari Molofsky, Christoph Schneider, Richard M. Locksley
Sci Immunol. Author manuscript; available in PMC 2022 Jun 4.
Published in final edited form as: Sci Immunol. 2022 Mar 4; 7(69): eabj1080. Published online 2022 Mar 4. doi: 10.1126/sciimmunol.abj1080
PMCID:
PMC9166270
AbstractArticlePDF–2.6M
19.
Interleukin-4 receptor signaling modulates neuronal network activity
Nicholas Hanuscheck, Carine Thalman, Micaela Domingues, Samantha Schmaul, Muthuraman Muthuraman, Florian Hetsch, Manuela Ecker, Heiko Endle, Mohammadsaleh Oshaghi, Gianvito Martino, Tanja Kuhlmann, Katarzyna Bozek, Tim van Beers, Stefan Bittner, Jakob von Engelhardt, Johannes Vogt, Christina Francisca Vogelaar, Frauke Zipp
J Exp Med. 2022 Jun 6; 219(6): e20211887. Published online 2022 May 19. doi: 10.1084/jem.20211887
PMCID:
PMC9123307
AbstractArticlePDF–6.9M
20.
GABAergic neuronal IL-4R mediates T cell effect on memory
Jasmin Herz, Zhongxiao Fu, Kyungdeok Kim, Taitea Dykstra, Morgan Wall, Huiping Li, Andrea Francesca Salvador, Bende Zou, Ni Yan, Susan Blackburn, Patrick H. Andrews, Dylan H. Goldman, Zachary Papadopoulos, Igor Smirnov, Xinmin S. Xie, Jonathan Kipnis
Neuron. Author manuscript; available in PMC 2022 Nov 17.
Published in final edited form as: Neuron. 2021 Nov 17; 109(22): 3609–3618.e9. doi: 10.1016/j.neuron.2021.10.022
PMCID:
PMC9116260
AbstractArticlePDF–1.8M

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