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Items: 1 to 20 of 100

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Interleukin-23 receptor signaling impairs the stability and function of colonic regulatory T cells
Justin Jacobse, Rachel E. Brown, Jing Li, Jennifer M. Pilat, Ly Pham, Sarah P. Short, Christopher T. Peek, Andrea Rolong, M. Kay Washington, Ruben Martinez-Barricarte, Mariana X. Byndloss, Catherine Shelton, Janet G. Markle, Yvonne L. Latour, Margaret M. Allaman, James E. Cassat, Keith T. Wilson, Yash A. Choksi, Christopher S. Williams, Ken S. Lau, Charles R. Flynn, Jean-Laurent Casanova, Edmond H.H.M. Rings, Janneke N. Samsom, Jeremy A. Goettel
Cell Rep. Author manuscript; available in PMC 2023 Oct 23.
Published in final edited form as: Cell Rep. 2023 Feb 28; 42(2): 112128. Published online 2023 Feb 17. doi: 10.1016/j.celrep.2023.112128
PMCID:
PMC10432575
AbstractArticlePDF–1.1M
3.
Induction of a colitogenic phenotype in Th1-like cells depends on interleukin 23 receptor signaling
Mathias Pawlak, David DeTomaso, Alexandra Schnell, Gerd Meyer zu Horste, Youjin Lee, Jackson Nyman, Danielle Dionne, Brianna M. L. Regan, Vasundhara Singh, Toni Delorey, Markus A. Schramm, Chao Wang, Antonia Wallrapp, Patrick R. Burkett, Samantha J. Riesenfeld, Ana C. Anderson, Aviv Regev, Ramnik J. Xavier, Nir Yosef, Vijay K. Kuchroo
Immunity. Author manuscript; available in PMC 2023 Sep 13.
Published in final edited form as: Immunity. 2022 Sep 13; 55(9): 1663–1679.e6. Published online 2022 Sep 6. doi: 10.1016/j.immuni.2022.08.007
PMCID:
PMC9808605
AbstractArticlePDF–3.2M
4.
Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis
Monica Viladomiu, Manirath Khounlotham, Belgin Dogan, Svetlana F. Lima, Ahmed Elsaadi, Emre Cardakli, Jim G. Castellanos, Charles Ng, Jeremy Herzog, Alexi A. Schoenborn, Melissa Ellermann, Bo Liu, Shiying Zhang, Ajay S. Gulati, R. Balfour Sartor, Kenneth W. Simpson, Steven M. Lipkin, Randy S. Longman
Cell Rep. Author manuscript; available in PMC 2023 Jan 1.
Published in final edited form as: Cell Rep. 2022 Nov 15; 41(7): 111637. doi: 10.1016/j.celrep.2022.111637
PMCID:
PMC9805753
AbstractArticlePDF–2.4M
5.
A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice
Carl-Philipp Hackstein, Dana Costigan, Linnea Drexhage, Claire Pearson, Samuel Bullers, Nicholas Ilott, Hossain Delowar Akther, Yisu Gu, Michael E. B. FitzPatrick, Oliver J. Harrison, Lucy C. Garner, Elizabeth H. Mann, Sumeet Pandey, Matthias Friedrich, Nicholas M. Provine, Holm H. Uhlig, Emanuele Marchi, Fiona Powrie, Paul Klenerman, Emily E. Thornton
Nat Commun. 2022; 13: 7472. Published online 2022 Dec 3. doi: 10.1038/s41467-022-35126-3
PMCID:
PMC9719512
AbstractArticlePDF–2.7M
6.
Interleukin‐23 receptor defines T helper 1‐like regulatory T cells in oral squamous cell carcinoma
Wei Li, Ning An, Mingwei Wang, Xiguo Liu, Zhidan Mei
Immun Inflamm Dis. 2022 Dec; 10(12): e746. Published online 2022 Nov 23. doi: 10.1002/iid3.746
PMCID:
PMC9682469
AbstractArticlePDF–3.9M
7.
lncRNA-GM targets Foxo1 to promote T cell–mediated autoimmunity
Yali Chen, Juan Liu, Xiaomin Zhang, Ha Zhu, Yujia Wang, Zhiqing Li, Yanfang Liu, Shuo Liu, Shuxun Liu, Nan Li, Kun Chen, Xuetao Cao
Sci Adv. 2022 Aug; 8(31): eabn9181. Published online 2022 Aug 5. doi: 10.1126/sciadv.abn9181
PMCID:
PMC9355365
AbstractArticlePDF–5.3M
8.
Allergic airway inflammation induces upregulation of the expression of IL-23R by macrophages and not in CD3 + T cells and CD11c+F4/80− dendritic cells of the lung
Maximilian Leitner, Sebastian Heck, Kenny Nguyen, Phu Quyen Nguyen, Shaza Harfoush, Eva Rosenkranz, Robert Bals, Quoc Thai Dinh
Cell Tissue Res. 2022; 389(1): 85–98. Published online 2022 Apr 27. doi: 10.1007/s00441-021-03538-0
PMCID:
PMC9200692
AbstractArticlePDF–2.1M
9.
Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity
Alexandra Schnell, Linglin Huang, Meromit Singer, Anvita Singaraju, Rocky M. Barilla, Brianna M. L. Regan, Alina Bollhagen, Pratiksha I. Thakore, Danielle Dionne, Toni M. Delorey, Mathias Pawlak, Gerd Meyer zu Horste, Orit Rozenblatt-Rosen, Rafael A. Irizarry, Aviv Regev, Vijay K. Kuchroo
Cell. Author manuscript; available in PMC 2022 Dec 22.
Published in final edited form as: Cell. 2021 Dec 22; 184(26): 6281–6298.e23. Published online 2021 Dec 6. doi: 10.1016/j.cell.2021.11.018
PMCID:
PMC8900676
AbstractArticlePDF–3.6M
10.
Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes
Teruyuki Sano, Takahiro Kageyama, Victoria Fang, Ranit Kedmi, Carlos Serafin Martinez, Jhimmy Talbot, Alessandra Chen, Ivan Cabrera, Oleksandra Gorshko, Reina Kurakake, Yi Yang, Charles Ng, Susan R. Schwab, Dan R. Littman
Cell Rep. Author manuscript; available in PMC 2022 Feb 15.
Published in final edited form as: Cell Rep. 2021 Aug 24; 36(8): 109608. doi: 10.1016/j.celrep.2021.109608
Correction in:
Cell Rep. 2021 Sep 21; 36(12): 109766.
PMCID:
PMC8845566
AbstractArticlePDF–3.8M
11.
IL-23/IL-17A/TRPV1 Axis Produces Mechanical Pain via Macrophage-Sensory Neuron Crosstalk in Female Mice
Xin Luo, Ouyang Chen, Zilong Wang, Sangsu Bang, Jasmine Ji, Sang Hoon Lee, Yul Huh, Kenta Furutani, Qianru He, Xueshu Tao, Mei-Chuan Ko, Andrey Bortsov, Christopher R Donnelly, Yong Chen, Andrea Nackley, Temugin Berta, Ru-Rong Ji
Neuron. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Neuron. 2021 Sep 1; 109(17): 2691–2706.e5. Published online 2021 Jul 19. doi: 10.1016/j.neuron.2021.06.015
PMCID:
PMC8425601
AbstractArticlePDF–5.1M
12.
IL-23 receptor deficiency results in lower bone mass via indirect regulation of bone formation
Wida Razawy, Celso H. Alves, Marijke Koedam, Patrick S. Asmawidjaja, Adriana M. C. Mus, Mohamed Oukka, Pieter J. M. Leenen, Jenny A. Visser, Bram C. J. van der Eerden, Erik Lubberts
Sci Rep. 2021; 11: 10244. Published online 2021 May 13. doi: 10.1038/s41598-021-89625-2
PMCID:
PMC8119722
AbstractArticlePDF–4.2M
13.
Adherent-Invasive E. coli metabolism of propanediol in Crohn’s disease regulates phagocytes to drive intestinal inflammation
Monica Viladomiu, Maeva L. Metz, Svetlana F. Lima, Wen-Bing Jin, Lance Chou, JRI Live Cell Bank, Chun-Jun Guo, Gretchen E. Diehl, Kenneth W. Simpson, Ellen J. Scherl, Randy S. Longman
Cell Host Microbe. Author manuscript; available in PMC 2022 Apr 14.
Published in final edited form as: Cell Host Microbe. 2021 Feb 2 : S1931-3128(21)00032-9. Published online 2021 Feb 2. doi: 10.1016/j.chom.2021.01.002
PMCID:
PMC8049981
AbstractArticlePDF–1.1M
14.
EBV-induced gene 3 augments IL-23Rα protein expression through a chaperone calnexin
Izuru Mizoguchi, Mio Ohashi, Hideaki Hasegawa, Yukino Chiba, Naoko Orii, Shinya Inoue, Chiaki Kawana, Mingli Xu, Katsuko Sudo, Koji Fujita, Masahiko Kuroda, Shin-ichi Hashimoto, Kouji Matsushima, Takayuki Yoshimoto
J Clin Invest. 2020 Nov 2; 130(11): 6124–6140. Published online 2020 Oct 12. doi: 10.1172/JCI122732
PMCID:
PMC7598073
AbstractArticlePDF–11M
15.
Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy
Lin Wu, Kate E.R. Hollinshead, Yuhan Hao, Christy Au, Lina Kroehling, Charles Ng, Woan-Yu Lin, Dayi Li, Hernandez Moura Silva, Jong Shin, Juan J. Lafaille, Richard Possemato, Michael E. Pacold, Thales Papagiannakopoulos, Alec C. Kimmelman, Rahul Satija, Dan R. Littman
Cell. Author manuscript; available in PMC 2021 Aug 6.
Published in final edited form as: Cell. 2020 Aug 6; 182(3): 641–654.e20. Published online 2020 Jul 1. doi: 10.1016/j.cell.2020.06.014
PMCID:
PMC7556360
AbstractArticlePDF–2.2M
16.
IL-23 signaling regulation of pro-inflammatory T-cell migration uncovered by phosphoproteomics
Candelas Álvarez-Salamero, Raquel Castillo-González, Gloria Pastor-Fernández, Isabel R. Mariblanca, Jesús Pino, Danay Cibrian, María N. Navarro
PLoS Biol. 2020 Mar; 18(3): e3000646. Published online 2020 Mar 23. doi: 10.1371/journal.pbio.3000646
PMCID:
PMC7117768
AbstractArticlePDF–4.4M
17.
Serum Amyloid A Proteins Induce Pathogenic TH17 Cells and Promote Inflammatory Disease
June-Yong Lee, Jason A. Hall, Lina Kroehling, Lin Wu, Tariq Najar, Henry H. Nguyen, Woan-Yu Lin, Stephen T. Yeung, Hernandez Moura Silva, Dayi Li, Ashley Hine, P’ng Loke, David Hudesman, Jerome C. Martin, Ephraim Kenigsberg, Miriam Merad, Kamal M. Khanna, Dan R. Littman
Cell. Author manuscript; available in PMC 2021 Jan 9.
Published in final edited form as: Cell. 2020 Jan 9; 180(1): 79–91.e16. Published online 2019 Dec 19. doi: 10.1016/j.cell.2019.11.026
Correction in:
Cell. 2020 Dec 23; 183(7): 2036–2039.
PMCID:
PMC7039443
AbstractArticlePDF–2.1M
18.
CD4+CCR6+ T cells, but not γδ T cells, are important for the IL‐23R‐dependent progression of antigen‐induced inflammatory arthritis in mice
Wida Razawy, Patrick S. Asmawidjaja, Anne‐Marie Mus, Nazike Salioska, Nadine Davelaar, Nicole Kops, Mohamed Oukka, C. Henrique Alves, Erik Lubberts
Eur J Immunol. 2020 Feb; 50(2): 245–255. Published online 2019 Nov 28. doi: 10.1002/eji.201948112
PMCID:
PMC7028107
AbstractArticlePDF–2.7M
19.
ERα Signaling Increased IL-17A Production in Th17 Cells by Upregulating IL-23R Expression, Mitochondrial Respiration, and Proliferation
Hubaida Fuseini, Jacqueline-Yvonne Cephus, Pingsheng Wu, J. Brooke Davis, Diana C. Contreras, Vivek D. Gandhi, Jeffrey C. Rathmell, Dawn C. Newcomb
Front Immunol. 2019; 10: 2740. Published online 2019 Nov 27. doi: 10.3389/fimmu.2019.02740
PMCID:
PMC6892971
AbstractArticlePDF–3.3M
20.
SerpinB1 controls encephalitogenic T helper cells in neuroinflammation
Lifei Hou, Deepak A. Rao, Koichi Yuki, Jessica Cooley, Lauren A. Henderson, A. Helena Jonsson, Dion Kaiserman, Mark P. Gorman, Peter A. Nigrovic, Phillip I. Bird, Burkhard Becher, Eileen Remold-O’Donnell
Proc Natl Acad Sci U S A. 2019 Oct 8; 116(41): 20635–20643. Published online 2019 Sep 23. doi: 10.1073/pnas.1905762116
PMCID:
PMC6789640
AbstractArticlePDF–2.0M

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