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Select item 103122111.

PIF1 Promotes Autophagy to Inhibit Chronic Hypoxia Induced Apoptosis of Pulmonary Artery Endothelial Cells

Yujing Zhao, Juan Wu, Shuai Guan, Ting Xue, Xiaolei Wei, Dawei Cao, Pengzhou Kong, Xinri Zhang

Int J Chron Obstruct Pulmon Dis. 2023; 18: 1319–1332. Published online 2023 Jun 26. doi: 10.2147/COPD.S406453

PMCID:: PMC10312211

Abstract Article PDF–12M

Select item 88611632.

CircNEIL3 mediates pyroptosis to influence lung adenocarcinoma radiotherapy by upregulating PIF1 through miR-1184 inhibition

Ting Zhang, Dong-Ming Wu, Peng-Wei Luo, Teng Liu, Rong Han, Shi-Hua Deng, Miao He, Yang-Yang Zhao, Ying Xu

Cell Death Dis. 2022 Feb; 13(2): 167. Published online 2022 Feb 21. doi: 10.1038/s41419-022-04561-x

PMCID:: PMC8861163

Abstract Article PDF–4.8M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80474404.

PIF1 helicase promotes break‐induced replication in mammalian cells

Shibo Li, Hailong Wang, Sanaa Jehi, Jun Li, Shuo Liu, Zi Wang, Lan Truong, Takuya Chiba, Zefeng Wang, Xiaohua Wu

EMBO J. 2021 Apr 15; 40(8): e104509. Published online 2021 Jan 20. doi: 10.15252/embj.2020104509

PMCID:: PMC8047440

Abstract Article PDF–1.0M

Select item 78870385.

Dynamic regulation of Pif1 acetylation is crucial to the maintenance of genome stability

Onyekachi E. Ononye, Christopher W. Sausen, Matthew L. Bochman, Lata Balakrishnan

Curr Genet. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Curr Genet. 2021 Feb; 67(1): 85–92. Published online 2020 Oct 20. doi: 10.1007/s00294-020-01116-5

PMCID:: PMC7887038

Abstract Article PDF–458K

Select item 72548496.

Mitochondrial genetic variation is enriched in G-quadruplex regions that stall DNA synthesis in vitro

Thomas J Butler, Katrina N Estep, Joshua A Sommers, Robert W Maul, Ann Zenobia Moore, Stefania Bandinelli, Francesco Cucca, Marcus A Tuke, Andrew R Wood, Sanjay Kumar Bharti, Daniel F Bogenhagen, Elena Yakubovskaya, Miguel Garcia-Diaz, Thomas A Guilliam, Alicia K Byrd, Kevin D Raney, Aidan J Doherty, Luigi Ferrucci, David Schlessinger, Jun Ding, Robert M Brosh, Jr

Hum Mol Genet. 2020 May 28; 29(8): 1292–1309. Published online 2020 Mar 19. doi: 10.1093/hmg/ddaa043

PMCID:: PMC7254849

Abstract Article PDF–1.4M

Select item 64511287.

Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase

Saba Dehghani-Tafti, Vladimir Levdikov, Alfred A Antson, Ben Bax, Cyril M Sanders

Nucleic Acids Res. 2019 Apr 8; 47(6): 3208–3222. Published online 2019 Jan 30. doi: 10.1093/nar/gkz028

PMCID:: PMC6451128

Abstract Article PDF–12M

Select item 55316118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 48416079.

High-throughput analyses of hnRNP H1 dissects its multi-functional aspect

Philip J. Uren, Emad Bahrami-Samani, Patricia Rosa de Araujo, Christine Vogel, Mei Qiao, Suzanne C. Burns, Andrew D. Smith, Luiz O. F. Penalva

RNA Biol. 2016 Apr; 13(4): 400–411. Published online 2016 Jan 13. doi: 10.1080/15476286.2015.1138030

PMCID:: PMC4841607

Abstract Article PDF–1.6M

Select item 435828210.

A Parallel Quadruplex DNA Is Bound Tightly but Unfolded Slowly by Pif1 Helicase

Alicia K. Byrd, Kevin D. Raney

J Biol Chem. 2015 Mar 6; 290(10): 6482–6494. Published online 2015 Jan 14. doi: 10.1074/jbc.M114.630749

PMCID:: PMC4358282

Abstract Article PDF–3.2M

Select item 429436111.

Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress

Mary E. Gagou, Anil Ganesh, Geraldine Phear, Darren Robinson, Eva Petermann, Angela Cox, Mark Meuth

Oncotarget. 2014 Nov; 5(22): 11381–11398. Published online 2014 Nov 5. doi: 10.18632/oncotarget.2501

PMCID:: PMC4294361

Abstract Article PDF–4.8M

Select item 390432112.

Determination of the biochemical properties of full-length human PIF1 ATPase

Yongqing Gu, Jianxiao Wang, Shanshan Li, Kenji Kamiya, Xiaohua Chen, Pingkun Zhou

Prion. 2013 Jul 1; 7(4): 341–347. Published online 2013 Aug 7. doi: 10.4161/pri.26022

PMCID:: PMC3904321

Abstract Article PDF–1.2M

Select item 368078913.

Pif1 family helicases suppress genome instability at G-quadruplex motifs

Katrin Paeschke, Matthew L. Bochman, P. Daniela Garcia, Petr Cejka, Katherine L. Friedman, Stephen C. Kowalczykowski, Virginia A. Zakian

Nature. Author manuscript; available in PMC 2013 Nov 23.

Published in final edited form as: Nature. 2013 May 23; 497(7450): 458–462. Published online 2013 May 8. doi: 10.1038/nature12149

PMCID:: PMC3680789

Abstract Article PDF–901K

Select item 366877414.

Yeast Pif1 Helicase Exhibits a One-base-pair Stepping Mechanism for Unwinding Duplex DNA

Ramanagouda Ramanagoudr-Bhojappa, Shubeena Chib, Alicia K. Byrd, Suja Aarattuthodiyil, Manjula Pandey, Smita S. Patel, Kevin D. Raney

J Biol Chem. 2013 May 31; 288(22): 16185–16195. Published online 2013 Apr 17. doi: 10.1074/jbc.M113.470013

PMCID:: PMC3668774

Abstract Article PDF–2.0M

Select item 357584415.

Alternative translation initiation augments the human mitochondrial proteome

Lawrence Kazak, Aurelio Reyes, Anna L. Duncan, Joanna Rorbach, Stuart R. Wood, Gloria Brea-Calvo, Payam A. Gammage, Alan J. Robinson, Michal Minczuk, Ian J. Holt

Nucleic Acids Res. 2013 Feb; 41(4): 2354–2369. Published online 2012 Dec 25. doi: 10.1093/nar/gks1347