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Select item 112624781.

Altered Elastin Turnover, Immune Response, and Age-Related Retinal Thinning in a Transgenic Mouse Model With RPE-Specific HTRA1 Overexpression

Soumya Navneet, Masaaki Ishii, Bärbel Rohrer

Invest Ophthalmol Vis Sci. 2024 Jul; 65(8): 34. Published online 2024 Jul 19. doi: 10.1167/iovs.65.8.34

PMCID:: PMC11262478

Abstract Article PDF–9.2M

Select item 109464382.

EphB1 controls long-range cortical axon guidance through a cell non-autonomous role in GABAergic cells

Ahlem Assali, George Chenaux, Jennifer Y. Cho, Stefano Berto, Nathan A. Ehrlich, Christopher W. Cowan

Development. 2024 Mar 1; 151(5): dev201439. Published online 2024 Feb 28. doi: 10.1242/dev.201439

PMCID:: PMC10946438

Abstract Article

Select item 107884613.

Presenilin-1 in smooth muscle cells facilitates hypermuscularization in elastin aortopathy

Junichi Saito, Jui M. Dave, Freddy Duarte Lau, Daniel M. Greif

iScience. 2024 Jan 19; 27(1): 108636. Published online 2023 Dec 13. doi: 10.1016/j.isci.2023.108636

PMCID:: PMC10788461

Abstract Article PDF–9.4M

Select item 107034194.

Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves

Rachel Queen, Moira Crosier, Lorraine Eley, Janet Kerwin, Jasmin E. Turner, Jianshi Yu, Ahlam Alqahtani, Tamilvendhan Dhanaseelan, Lynne Overman, Hannah Soetjoadi, Richard Baldock, Jonathan Coxhead, Veronika Boczonadi, Alex Laude, Simon J. Cockell, Maureen A. Kane, Steven Lisgo, Deborah J. Henderson

PLoS Genet. 2023 Nov; 19(11): e1010777. Published online 2023 Nov 27. doi: 10.1371/journal.pgen.1010777

PMCID:: PMC10703419

Abstract Article PDF–9.6M

Select item 105473005.

Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development

Bingruo Wu, Brian Wu, Sonia Benkaci, Lijie Shi, Pengfei Lu, Taeju Park, Bernice E. Morrow, Yidong Wang, Bin Zhou

J Am Heart Assoc. 2023 Sep 19; 12(18): e029683. Published online 2023 Sep 13. doi: 10.1161/JAHA.123.029683

PMCID:: PMC10547300

Abstract Article PDF–41M

Select item 105277896.

High-Intensity Focused Ultrasound Increases Collagen and Elastin Fiber Synthesis by Modulating Caveolin-1 in Aging Skin

Seyeon Oh, Do-Young Rhee, Sosorburam Batsukh, Kuk Hui Son, Kyunghee Byun

Cells. 2023 Sep; 12(18): 2275. Published online 2023 Sep 14. doi: 10.3390/cells12182275

PMCID:: PMC10527789

Abstract Article PDF–7.0M

Select item 103904927.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 102438268.

Polarized localization of phosphatidylserine in the endothelium regulates Kir2.1

Claire A. Ruddiman, Richard Peckham, Melissa A. Luse, Yen-Lin Chen, Maniselvan Kuppusamy, Bruce A. Corliss, P. Jordan Hall, Chien-Jung Lin, Shayn M. Peirce, Swapnil K. Sonkusare, Robert P. Mecham, Jessica E. Wagenseil, Brant E. Isakson

JCI Insight. 2023 May 8; 8(9): e165715. Published online 2023 May 8. doi: 10.1172/jci.insight.165715

PMCID:: PMC10243826

Abstract Article PDF–66M

Select item 102183689.

Mechanical loading is required for initiation of extracellular matrix deposition at the developing murine myotendinous junction

Sarah N. Lipp, Kathryn R. Jacobson, Haley A. Colling, Tyler G. Tuttle, Dalton T. Miles, Kaitlin P. McCreery, Sarah Calve

Matrix Biol. Author manuscript; available in PMC 2024 Feb 1.

Published in final edited form as: Matrix Biol. 2023 Feb; 116: 28–48. Published online 2023 Jan 26. doi: 10.1016/j.matbio.2023.01.003

PMCID:: PMC10218368

Abstract Article PDF–2.2M

Select item 1016705010.

Elastin haploinsufficiency accelerates age-related structural and functional changes in the renal microvasculature and impairment of renal hemodynamics in female mice

Alethia J. Dixon, Patrick Osei-Owusu

Front Physiol. 2023; 14: 1141094. Published online 2023 Apr 25. doi: 10.3389/fphys.2023.1141094

PMCID:: PMC10167050

Abstract Article PDF–3.1M

Select item 968701811.

CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth

Prashant Chandrasekaran, Nicholas M. Negretti, Aravind Sivakumar, Derek C. Liberti, Hongbo Wen, Maureen Peers de Nieuwburgh, Joanna Y. Wang, Nigel S. Michki, Fatima N. Chaudhry, Sukhmani Kaur, MinQi Lu, Annabelle Jin, Jarod A. Zepp, Lisa R. Young, Jennifer M. S. Sucre, David B. Frank

Development. 2022 Nov 1; 149(21): dev200909. Published online 2022 Oct 31. doi: 10.1242/dev.200909

PMCID:: PMC9687018

Abstract Article

Select item 968184312.

Angiopoietin-like 2 is essential to aortic valve development in mice

Pauline Labbé, Victoria Munoz Goyette, Nathalie Thorin-Trescases, Louis Villeneuve, Ines Desanlis, Constance Delwarde, Yan-Fen Shi, Cécile Martel, Carol Yu, Azadeh Alikashani, Maya Mamarbachi, Frédéric Lesage, Samuel Mathieu, Jean-Claude Tardif, Patrick Mathieu, Marie Kmita, Éric Thorin

Commun Biol. 2022; 5: 1277. Published online 2022 Nov 21. doi: 10.1038/s42003-022-04243-6

PMCID:: PMC9681843

Abstract Article PDF–13M

Select item 954690613.

Vascular smooth muscle RhoA counteracts abdominal aortic aneurysm formation by modulating MAP4K4 activity

Md Rasel Molla, Akio Shimizu, Masahiro Komeno, Nor Idayu A. Rahman, Joanne Ern Chi Soh, Le Kim Chi Nguyen, Mahbubur Rahman Khan, Wondwossen Wale Tesega, Si Chen, Xiaoling Pang, Miki Tanaka-Okamoto, Noriyuki Takashima, Akira Sato, Tomoaki Suzuki, Hisakazu Ogita

Commun Biol. 2022; 5: 1071. Published online 2022 Oct 7. doi: 10.1038/s42003-022-04042-z

PMCID:: PMC9546906

Abstract Article PDF–5.3M

Select item 937592614.

Upregulation of key genes Eln and Tgfb3 were associated with the severity of cardiac hypertrophy

Rui Zhang, Xuan Xu, Xi Chen, Chunshu Hao, Zhenjun Ji, Pengfei Zuo, Mingming Yang, Genshan Ma, Yongjun Li

BMC Genomics. 2022; 23: 592. Published online 2022 Aug 14. doi: 10.1186/s12864-022-08778-0

PMCID:: PMC9375926

Abstract Article PDF–3.2M

Select item 930666215.

Developmentally interdependent stretcher‐compressor relationship between the embryonic brain and the surrounding scalp in the preosteogenic head

Koichiro Tsujikawa, Kanako Saito, Arata Nagasaka, Takaki Miyata

Dev Dyn. 2022 Jul; 251(7): 1107–1122. Published online 2022 Jan 21. doi: 10.1002/dvdy.451

PMCID:: PMC9306662

Abstract Article PDF–6.8M

Select item 927941416.

A SOX17-PDGFB signaling axis regulates aortic root development

Pengfei Lu, Ping Wang, Bingruo Wu, Yidong Wang, Yang Liu, Wei Cheng, Xuhui Feng, Xinchun Yuan, Miriam M. Atteya, Haleigh Ferro, Yukiko Sugi, Grant Rydquist, Mahdi Esmaily, Jonathan T. Butcher, Ching-Pin Chang, Jack Lenz, Deyou Zheng, Bin Zhou

Nat Commun. 2022; 13: 4065. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31815-1

PMCID:: PMC9279414

Abstract Article PDF–11M

Select item 918035817.

Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia

Yi Gong, Fiza Laheji, Anna Berenson, April Qian, Sang-O Park, Rene Kok, Martin Selig, Ryan Hahn, Reza Sadjadi, Stephan Kemp, Florian Eichler

Cells. 2022 Jun; 11(11): 1842. Published online 2022 Jun 4. doi: 10.3390/cells11111842

PMCID:: PMC9180358

Abstract Article PDF–4.6M

Select item 916052818.

Elastin Insufficiency Confers Proximal and Distal Pulmonary Vasculopathy in Mice, Partially Remedied by the K_ATP Channel Opener Minoxidil: Considerations and Cautions for the Treatment of People With Williams-Beuren Syndrome

Russell H. Knutsen, Leah M. Gober, Elise K. Kronquist, Maninder Kaur, Danielle R. Donahue, Danielle Springer, Zu Xi Yu, Marcus Y. Chen, Yi-Ping Fu, Feri Choobdar, My-Le Nguyen, Sharon Osgood, Joy L. Freeman, Neelam Raja, Mark D. Levin, Beth A. Kozel

Front Cardiovasc Med. 2022; 9: 886813. Published online 2022 May 19. doi: 10.3389/fcvm.2022.886813

PMCID:: PMC9160528

Abstract Article PDF–3.6M

Select item 898800819.

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

Ann-Helen Rosendahl, Mia Monnius, Anu Laitala, Antti Railo, Ilkka Miinalainen, Ritva Heljasvaara, Joni M. Mäki, Johanna Myllyharju

J Biol Chem. 2022 Apr; 298(4): 101787. Published online 2022 Mar 2. doi: 10.1016/j.jbc.2022.101787

PMCID:: PMC8988008

Abstract Article PDF–6.1M

Select item 888491120.

JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency

Jui M. Dave, Raja Chakraborty, Aglaia Ntokou, Junichi Saito, Fatima Z. Saddouk, Zhonghui Feng, Ashish Misra, George Tellides, Robert K. Riemer, Zsolt Urban, Caroline Kinnear, James Ellis, Seema Mital, Robert Mecham, Kathleen A. Martin, Daniel M. Greif

J Clin Invest. 2022 Mar 1; 132(5): e142338. Published online 2022 Mar 1. doi: 10.1172/JCI142338

PMCID:: PMC8884911

Abstract Article PDF–3.3M

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