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Select item 111469661.

The plasminogen activator system: biology and regulation

J. P. Irigoyen, P. Muñoz-Cánoves, L. Montero, M. Koziczak, Y. Nagamine

Cell Mol Life Sci. 1999 Oct; 56(1-2): 104–132. doi: 10.1007/PL00000615

PMCID:: PMC11146966

Abstract Article PDF–222K

Select item 111093702.

Plasminogen activator inhibitor-1 promotes immune evasion in tumors by facilitating the expression of programmed cell death-ligand 1

Abd Aziz Ibrahim, Taku Fujimura, Tomoko Uno, Tomoya Terada, Ken-ichi Hirano, Hiroyuki Hosokawa, Akio Ohta, Toshio Miyata, Kiyoshi Ando, Takashi Yahata

Front Immunol. 2024; 15: 1365894. Published online 2024 May 8. doi: 10.3389/fimmu.2024.1365894

PMCID:: PMC11109370

Abstract Article PDF–6.3M

Select item 110728773.

PAI-1 production by reactive astrocytes drives tissue dysfibrinolysis in multiple sclerosis models

Héloïse Lebas, Sylvaine Guérit, Audrey Picot, Anne Cécile Boulay, Antoine Fournier, Denis Vivien, Martine Cohen Salmon, Fabian Docagne, Isabelle Bardou

Cell Mol Life Sci. 2022 Jun; 79(6): 323. Published online 2022 May 28. doi: 10.1007/s00018-022-04340-z

PMCID:: PMC11072877

Abstract Article PDF–16M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108911545.

Modulation of cAMP/cGMP signaling as prevention of congenital heart defects in Pde2A deficient embryos: a matter of oxidative stress

Silvia Cardarelli, Martina Biglietto, Tiziana Orsini, Valentina Fustaino, Lucia Monaco, Ana Gabriela de Oliveira do Rêgo, Francesca Liccardo, Silvia Masciarelli, Francesco Fazi, Fabio Naro, Luciana De Angelis, Manuela Pellegrini

Cell Death Dis. 2024 Feb; 15(2): 169. Published online 2024 Feb 23. doi: 10.1038/s41419-024-06549-1

PMCID:: PMC10891154

Abstract Article PDF–2.6M

Select item 104174286.

PAI-1 Regulation of p53 Expression and Senescence in Type II Alveolar Epithelial Cells

Tapasi Rana, Chunsun Jiang, Sami Banerjee, Nengjun Yi, Jaroslaw W. Zmijewski, Gang Liu, Rui-Ming Liu

Cells. 2023 Aug; 12(15): 2008. Published online 2023 Aug 5. doi: 10.3390/cells12152008

PMCID:: PMC10417428

Abstract Article PDF–4.0M

Select item 104038757.

PAI1 inhibits the pathogenesis of primary focal hyperhidrosis by targeting CHRNA1

Jian-Feng Chen, Min Lin, Xu Li, Jian-Bo Lin

Orphanet J Rare Dis. 2023; 18: 205. Published online 2023 Jul 21. doi: 10.1186/s13023-023-02808-0

PMCID:: PMC10403875

Abstract Article PDF–2.3M

Select item 103757818.

PAI-1 regulates AT2-mediated re-alveolarization and ion permeability

Gibran Ali, Mo Zhang, Jianjun Chang, Runzhen Zhao, Yang Jin, Jiwang Zhang, Hong-Long Ji

Stem Cell Res Ther. 2023; 14: 185. Published online 2023 Jul 27. doi: 10.1186/s13287-023-03414-4

PMCID:: PMC10375781

Abstract Article PDF–1.5M

Select item 101923959.

SIRT6-PAI-1 axis is a promising therapeutic target in aging-related bone metabolic disruption

Alkebaier Aobulikasimu, Tao Liu, Jinying Piao, Shingo Sato, Hiroki Ochi, Atsushi Okawa, Kunikazu Tsuji, Yoshinori Asou

Sci Rep. 2023; 13: 7991. Published online 2023 May 17. doi: 10.1038/s41598-023-33297-7

PMCID:: PMC10192395

Abstract Article PDF–7.9M

Select item 1015801810.

Plasminogen Activator Inhibitor-1 Potentiates Neutrophil Infiltration and Tissue Injury in Colitis

Xinqiong Wang, Li Guo, Jiebin Huang, Shaowei Jiang, Na Li, Hong-Hua Mu, Chundi Xu

Int J Biol Sci. 2023; 19(7): 2132–2149. Published online 2023 Apr 9. doi: 10.7150/ijbs.75890

PMCID:: PMC10158018

Abstract Article PDF–8.2M

Select item 986775111.

Obesity promotes radioresistance through SERPINE1-mediated aggressiveness and DNA repair of triple-negative breast cancer

Yong-Han Su, Yi-Zhen Wu, David K. Ann, Jenny Ling-Yu Chen, Ching-Ying Kuo

Cell Death Dis. 2023 Jan; 14(1): 53. Published online 2023 Jan 21. doi: 10.1038/s41419-023-05576-8

PMCID:: PMC9867751

Abstract Article PDF–4.4M

Select item 960293912.

Wnt5a/β-catenin axis is involved in the downregulation of AT2 lineage by PAI-1

Krishan G. Jain, Runzhen Zhao, Yang Liu, Xuan Guo, Guohua Yi, Hong-Long Ji

Am J Physiol Lung Cell Mol Physiol. 2022 Nov 1; 323(5): L515–L524. Published online 2022 Sep 13. doi: 10.1152/ajplung.00202.2022

PMCID:: PMC9602939

Abstract Article

Select item 934946813.

Compartmentalized actions of the plasminogen activator inhibitors, PAI-1 and Nsp in ischemic stroke

Daniel Torrente, Enming Joseph Su, Linda Fredriksson, Mark Warnock, David Bushart, Kris Mann, Cory D. Emal, Daniel A. Lawrence

Transl Stroke Res. Author manuscript; available in PMC 2023 Oct 1.

Published in final edited form as: Transl Stroke Res. 2022 Oct; 13(5): 801–815. Published online 2022 Feb 4. doi: 10.1007/s12975-022-00992-y

PMCID:: PMC9349468

Abstract Article PDF–1.6M

Select item 930609914.

Interplay of Helicobacter pylori, fibroblasts, and cancer cells induces fibroblast activation and serpin E1 expression by cancer cells to promote gastric tumorigenesis

Xueshu Chen, Wei Chen, Yan Zhao, Qinrong Wang, Wenling Wang, Yining Xiang, Hang Yuan, Yuan Xie, Jianjiang Zhou

J Transl Med. 2022; 20: 322. Published online 2022 Jul 21. doi: 10.1186/s12967-022-03537-x

PMCID:: PMC9306099

Abstract Article PDF–13M

Select item 922172415.

Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis

Vahid Kheirollahi, Ali Khadim, Georgios Kiliaris, Martina Korfei, Margarida Maria Barroso, Ioannis Alexopoulos, Ana Ivonne Vazquez-Armendariz, Malgorzata Wygrecka, Clemens Ruppert, Andreas Guenther, Werner Seeger, Susanne Herold, Elie El Agha

Cells. 2022 Jun; 11(12): 1973. Published online 2022 Jun 20. doi: 10.3390/cells11121973

PMCID:: PMC9221724

Abstract Article PDF–128M

Select item 919703216.

Aberrant induction of p19^Arf-mediated cellular senescence contributes to neurodevelopmental defects

Muriel Rhinn, Irene Zapata-Bodalo, Annabelle Klein, Jean-Luc Plassat, Tania Knauer-Meyer, William M. Keyes

PLoS Biol. 2022 Jun; 20(6): e3001664. Published online 2022 Jun 14. doi: 10.1371/journal.pbio.3001664

PMCID:: PMC9197032

Abstract Article PDF–3.1M

Select item 898800817.

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

Ann-Helen Rosendahl, Mia Monnius, Anu Laitala, Antti Railo, Ilkka Miinalainen, Ritva Heljasvaara, Joni M. Mäki, Johanna Myllyharju

J Biol Chem. 2022 Apr; 298(4): 101787. Published online 2022 Mar 2. doi: 10.1016/j.jbc.2022.101787

PMCID:: PMC8988008

Abstract Article PDF–6.1M

Select item 874528518.

Role of Macrophages and Plasminogen Activator Inhibitor-1 in Delayed Bone Repair Induced by Glucocorticoids in Mice

Kiyotaka Okada, Naoyuki Kawao, Daisho Nakai, Rei Wakabayashi, Yoshitaka Horiuchi, Katsumi Okumoto, Shinji Kurashimo, Yoshimasa Takafuji, Osamu Matsuo, Hiroshi Kaji

Int J Mol Sci. 2022 Jan; 23(1): 478. Published online 2022 Jan 1. doi: 10.3390/ijms23010478

PMCID:: PMC8745285

Abstract Article PDF–2.4M

Select item 874525919.

Activated Protein C Protects against Murine Contact Dermatitis by Suppressing Protease-Activated Receptor 2

Meilang Xue, Haiyan Lin, Ruilong Zhao, Callum Fryer, Lyn March, Christopher J. Jackson

Int J Mol Sci. 2022 Jan; 23(1): 516. Published online 2022 Jan 3. doi: 10.3390/ijms23010516

PMCID:: PMC8745259

Abstract Article PDF–39M

Select item 858931020.

Adhesion G protein–coupled receptor Gpr126/Adgrg6 is essential for placental development

Rebeca Torregrosa-Carrión, Rebeca Piñeiro-Sabarís, Marcos Siguero-Álvarez, Joaquím Grego-Bessa, Luis Luna-Zurita, Vitor Samuel Fernandes, Donal MacGrogan, Didier Y. R. Stainier, José Luis de la Pompa

Sci Adv. 2021 Nov; 7(46): eabj5445. Published online 2021 Nov 12. doi: 10.1126/sciadv.abj5445

PMCID:: PMC8589310

Abstract Article PDF–19M

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