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Select item 111905731.

TBX3 is essential for establishment of the posterior boundary of anterior genes and upregulation of posterior genes together with HAND2 during the onset of limb bud development

Geoffrey Soussi, Ausra Girdziusaite, Shalu Jhanwar, Victorio Palacio, Marco Notaro, Rushikesh Sheth, Rolf Zeller, Aimée Zuniga

Development. 2024 Jun 1; 151(11): dev202722. Published online 2024 Jun 3. doi: 10.1242/dev.202722

PMCID:: PMC11190573

Abstract Article

Select item 107114822.

Maf1 controls retinal neuron number by both RNA Pol III- and Pol II-dependent mechanisms

Yifei Li, Dongchang Xiao, Haiqiao Chen, X.F. Steven Zheng, Mengqing Xiang

iScience. 2023 Dec 15; 26(12): 108544. Published online 2023 Nov 23. doi: 10.1016/j.isci.2023.108544

PMCID:: PMC10711482

Abstract Article PDF–9.9M

Select item 104107173.

Steroidogenic factor 1 (SF-1; Nr5a1) regulates the formation of the ovarian reserve

Camilla H. K. Hughes, Olivia E. Smith, Marie-Charlotte Meinsohn, Mylène Brunelle, Nicolas Gévry, Bruce D. Murphy

Proc Natl Acad Sci U S A. 2023 Aug 8; 120(32): e2220849120. Published online 2023 Jul 26. doi: 10.1073/pnas.2220849120

PMCID:: PMC10410717

Abstract Article PDF–3.9M

Select item 103359374.

Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis

Abhishek Sampath Kumar, Luyi Tian, Adriano Bolondi, Amèlia Aragonés Hernández, Robert Stickels, Helene Kretzmer, Evan Murray, Lars Wittler, Maria Walther, Gabriel Barakat, Leah Haut, Yechiel Elkabetz, Evan Z. Macosko, Léo Guignard, Fei Chen, Alexander Meissner

Nat Genet. 2023; 55(7): 1176–1185. Published online 2023 Jul 6. doi: 10.1038/s41588-023-01435-6

PMCID:: PMC10335937

Abstract Article PDF–25M

Select item 102026595.

IRX5 promotes DNA damage repair and activation of hair follicle stem cells

Jefferson K. Chen, Julie Wiedemann, Ly Nguyen, Zhongqi Lin, Mahum Tahir, Chi-Chung Hui, Maksim V. Plikus, Bogi Andersen

Stem Cell Reports. 2023 May 9; 18(5): 1227–1243. Published online 2023 Apr 20. doi: 10.1016/j.stemcr.2023.03.013

PMCID:: PMC10202659

Abstract Article PDF–6.8M

Select item 89401776.

Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity

Catarina Catela, Yihan Chen, Yifei Weng, Kailong Wen, Paschalis Kratsios

eLife. 2022; 11: e70766. Published online 2022 Mar 22. doi: 10.7554/eLife.70766

PMCID:: PMC8940177

Abstract Article PDF–6.0M

Select item 85893107.

Adhesion G protein–coupled receptor Gpr126/Adgrg6 is essential for placental development

Rebeca Torregrosa-Carrión, Rebeca Piñeiro-Sabarís, Marcos Siguero-Álvarez, Joaquím Grego-Bessa, Luis Luna-Zurita, Vitor Samuel Fernandes, Donal MacGrogan, Didier Y. R. Stainier, José Luis de la Pompa

Sci Adv. 2021 Nov; 7(46): eabj5445. Published online 2021 Nov 12. doi: 10.1126/sciadv.abj5445

PMCID:: PMC8589310

Abstract Article PDF–19M

Select item 85502508.

Ectopic expression of Irx3 and Irx5 in the paraventricular nucleus of the hypothalamus contributes to defects in Sim1 haploinsufficiency

Joe Eun Son, Zhengchao Dou, Siyi Wanggou, Jade Chan, Rong Mo, Xuejun Li, Xi Huang, Kyoung-Han Kim, Jacques L. Michaud, Chi-chung Hui

Sci Adv. 2021 Oct; 7(44): eabh4503. Published online 2021 Oct 27. doi: 10.1126/sciadv.abh4503

PMCID:: PMC8550250

Abstract Article PDF–40M

Select item 83860039.

Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5

Débora R. Sobreira, Amelia C. Joslin, Qi Zhang, Iain Williamson, Grace T. Hansen, Kathryn M. Farris, Noboru J. Sakabe, Nasa Sinnott-Armstrong, Grazyna Bozek, Sharon O. Jensen-Cody, Kyle H. Flippo, Carole Ober, Wendy A. Bickmore, Matthew Potthoff, Mengjie Chen, Melina Claussnitzer, Ivy Aneas, Marcelo A. Nóbrega

Science. Author manuscript; available in PMC 2022 Jun 4.

Published in final edited form as: Science. 2021 Jun 4; 372(6546): 1085–1091. doi: 10.1126/science.abf1008

PMCID:: PMC8386003

Abstract Article PDF–1.3M

Select item 817003910.

Tangential Intrahypothalamic Migration of the Mouse Ventral Premamillary Nucleus and Fgf8 Signaling

Lara López-González, Antonia Alonso, Elena García-Calero, Eduardo de Puelles, Luis Puelles

Front Cell Dev Biol. 2021; 9: 676121. Published online 2021 May 19. doi: 10.3389/fcell.2021.676121

PMCID:: PMC8170039

Abstract Article PDF–7.9M

Select item 782271011.

IRX3 and IRX5 collaborate during ovary development and follicle formation to establish responsive granulosa cells in the adult mouse

Anqi Fu, Megan L Koth, Ryan M Brown, Sarah A Shaw, Linda Wang, Kathleen J Krentz, Xiaoyun Zhang, Chi-chung Hui, Joan S Jorgensen

Biol Reprod. 2020 Sep; 103(3): 620–629. Published online 2020 Jun 8. doi: 10.1093/biolre/ioaa100

PMCID:: PMC7822710

Abstract Article PDF–1.4M

Select item 767350012.

In silico analysis identifies a putative cell-of-origin for BRAF fusion-positive cerebellar pilocytic astrocytoma

Subhi Talal Younes, Betty Herrington

PLoS One. 2020; 15(11): e0242521. Published online 2020 Nov 18. doi: 10.1371/journal.pone.0242521

PMCID:: PMC7673500

Abstract Article PDF–2.8M

Select item 756148713.

IRX3/5 regulate mitotic chromatid segregation and limb bud shape

Hirotaka Tao, Jean-Philippe Lambert, Theodora M. Yung, Min Zhu, Noah A. Hahn, Danyi Li, Kimberly Lau, Kendra Sturgeon, Vijitha Puviindran, Xiaoyun Zhang, Wuming Gong, Xiao Xiao Chen, Gregory Anderson, Daniel J. Garry, R. Mark Henkelman, Yu Sun, Angelo Iulianella, Yasuhiko Kawakami, Anne-Claude Gingras, Chi-chung Hui, Sevan Hopyan

Development. 2020 Oct 1; 147(19): dev180042. Published online 2020 Oct 5. doi: 10.1242/dev.180042

PMCID:: PMC7561487

Abstract Article

Select item 713283714.

Canonical Wnt/β-catenin activity and differential epigenetic marks direct sexually dimorphic regulation of Irx3 and Irx5 in developing mouse gonads

Megan L. Koth, S. Alexandra Garcia-Moreno, Annie Novak, Kirsten A. Holthusen, Anbarasi Kothandapani, Keer Jiang, Makoto Mark Taketo, Barbara Nicol, Humphrey H.-C. Yao, Christopher R. Futtner, Danielle M. Maatouk, Joan S. Jorgensen

Development. 2020 Mar 15; 147(6): dev183814. Published online 2020 Mar 30. doi: 10.1242/dev.183814

PMCID:: PMC7132837

Abstract Article

Select item 704444515.

Notch signalling regulates epibranchial placode patterning and segregation

Li Wang, Junjie Xie, Haoran Zhang, Long Hin Tsang, Sze Lan Tsang, Eike-Benjamin Braune, Urban Lendahl, Mai Har Sham

Development. 2020 Feb 15; 147(4): dev183665. Published online 2020 Feb 17. doi: 10.1242/dev.183665

PMCID:: PMC7044445

Abstract Article

Select item 677781116.

Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction

Reddemma Sandireddy, Dasan Mary Cibi, Priyanka Gupta, Anamika Singh, Nicole Tee, Akiyoshi Uemura, Jonathan A. Epstein, Manvendra K. Singh

JCI Insight. 2019 Aug 22; 4(16): e125908. Published online 2019 Aug 22. doi: 10.1172/jci.insight.125908

PMCID:: PMC6777811

Abstract Article PDF–21M

Select item 667118017.

Genetic Control of Circuit Function: Vsx1 and Irx5 Transcription Factors Regulate Contrast Adaptation in the Mouse Retina

Daniel Kerschensteiner, Haiquan Liu, Chi Wa Cheng, Jay Demas, Shuk Han Cheng, Chi-chung Hui, Robert L. Chow, Rachel O. L. Wong

J Neurosci. 2008 Mar 5; 28(10): 2342–2352. doi: 10.1523/JNEUROSCI.4784-07.2008

PMCID:: PMC6671180

Abstract Article PDF–648K

Select item 662924018.

Tie2 regulates endocardial sprouting and myocardial trabeculation

Xianghu Qu, Cristina Harmelink, H. Scott Baldwin

JCI Insight. 2019 Jul 11; 4(13): e96002. Published online 2019 Jul 11. doi: 10.1172/jci.insight.96002

PMCID:: PMC6629240

Abstract Article PDF–60M

Select item 662914819.

Targeted genetic screening in mice through haploid embryonic stem cells identifies critical genes in bone development

Meizhu Bai, Yujiao Han, Yuxuan Wu, Jiaoyang Liao, Lin Li, Lijun Wang, Qing Li, Wenhui Xing, Luonan Chen, Weiguo Zou, Jinsong Li

PLoS Biol. 2019 Jul; 17(7): e3000350. Published online 2019 Jul 2. doi: 10.1371/journal.pbio.3000350

PMCID:: PMC6629148

Abstract Article PDF–4.9M

Select item 658817020.

The Iroquois homeobox proteins IRX3 and IRX5 have distinct roles in Wilms tumour development and human nephrogenesis

Linda Holmquist Mengelbier, Simon Lindell‐Munther, Hiroaki Yasui, Caroline Jansson, Javanshir Esfandyari, Jenny Karlsson, Kimberly Lau, Chi‐chung Hui, Daniel Bexell, Sevan Hopyan, David Gisselsson

J Pathol. 2019 Jan; 247(1): 86–98. Published online 2018 Nov 29. doi: 10.1002/path.5171

PMCID:: PMC6588170

Abstract Article PDF–5.4M

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