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Select item 103783181.

Long-Term—But Not Short-Term—Plasticity at the Mossy Fiber–CA3 Pyramidal Cell Synapse in Hippocampus Is Altered in M1/M3 Muscarinic Acetylcholine Receptor Double Knockout Mice

Fang Zheng, Jürgen Wess, Christian Alzheimer

Cells. 2023 Jul; 12(14): 1890. Published online 2023 Jul 19. doi: 10.3390/cells12141890

PMCID:: PMC10378318

Abstract Article PDF–1.7M

Select item 98518102.

The M3 Muscarinic Acetylcholine Receptor Promotes Epidermal Differentiation

Junyan Duan, Charles Grando, Shuman Liu, Alex Chernyavsky, Jefferson K. Chen, Bogi Andersen, Sergei A. Grando

J Invest Dermatol. Author manuscript; available in PMC 2023 Jan 19.

Published in final edited form as: J Invest Dermatol. 2022 Dec; 142(12): 3211–3221.e2. Published online 2022 Jul 21. doi: 10.1016/j.jid.2022.06.013

PMCID:: PMC9851810

Abstract Article PDF–2.2M

Select item 85775593.

Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle

Qian Wang, Wendy Wing Sze Yue, Zheng Jiang, Tian Xue, Shin H. Kang, Dwight E. Bergles, Katsuhiko Mikoshiba, Stefan Offermanns, King-Wai Yau

Curr Biol. Author manuscript; available in PMC 2021 Nov 9.

Published in final edited form as: Curr Biol. 2017 Jun 19; 27(12): 1791–1800.e5. Published online 2017 Jun 1. doi: 10.1016/j.cub.2017.05.022

PMCID:: PMC8577559

Abstract Article PDF–1.7M

Select item 84923274.

Pancreas-specific CHRM3 activation causes pancreatitis in mice

Jianhua Wan, Jiale Wang, Larry E. Wagner, II, Oliver H. Wang, Fu Gui, Jiaxiang Chen, Xiaohui Zhu, Ashley N. Haddock, Brandy H. Edenfield, Brian Haight, Debabrata Mukhopadhyay, Ying Wang, David I. Yule, Yan Bi, Baoan Ji

JCI Insight. 2021 Sep 8; 6(17): e132585. Published online 2021 Sep 8. doi: 10.1172/jci.insight.132585

PMCID:: PMC8492327

Abstract Article PDF–21M

Select item 83216695.

Muscarinic receptor M3 contributes to intestinal stem cell maintenance via EphB/ephrin-B signaling

Toshio Takahashi, Akira Shiraishi, Jun Murata, Shin Matsubara, Satsuki Nakaoka, Shinji Kirimoto, Masatake Osawa

Life Sci Alliance. 2021 Sep; 4(9): e202000962. Published online 2021 Jul 9. doi: 10.26508/lsa.202000962

PMCID:: PMC8321669

Abstract Article PDF–3.4M

Select item 83132396.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 82011077.

Aged Mice Devoid of the M₃ Muscarinic Acetylcholine Receptor Develop Mild Dry Eye Disease

Aytan Musayeva, Subao Jiang, Yue Ruan, Jenia Kouchek Zadeh, Panagiotis Chronopoulos, Norbert Pfeiffer, Werner E.G. Müller, Maximilian Ackermann, Ning Xia, Huige Li, Adrian Gericke

Int J Mol Sci. 2021 Jun; 22(11): 6133. Published online 2021 Jun 7. doi: 10.3390/ijms22116133

PMCID:: PMC8201107

Abstract Article PDF–9.1M

Select item 79387708.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78319289.

Functions of Muscarinic Receptor Subtypes in Gastrointestinal Smooth Muscle: A Review of Studies with Receptor-Knockout Mice

Yasuyuki Tanahashi, Seiichi Komori, Hayato Matsuyama, Takio Kitazawa, Toshihiro Unno

Int J Mol Sci. 2021 Jan; 22(2): 926. Published online 2021 Jan 18. doi: 10.3390/ijms22020926

PMCID:: PMC7831928

Abstract Article PDF–1.5M

Select item 765241910.

Chronic postnatal chemogenetic activation of forebrain excitatory neurons evokes persistent changes in mood behavior

Sthitapranjya Pati, Kamal Saba, Sonali S Salvi, Praachi Tiwari, Pratik R Chaudhari, Vijaya Verma, Sourish Mukhopadhyay, Darshana Kapri, Shital Suryavanshi, James P Clement, Anant B Patel, Vidita A Vaidya

eLife. 2020; 9: e56171. Published online 2020 Sep 21. doi: 10.7554/eLife.56171

PMCID:: PMC7652419

Abstract Article PDF–3.7M

Select item 740852011.

The Constitutive Lack of α7 Nicotinic Receptor Leads to Metabolic Disorders in Mouse

Blandine Gausserès, Junjun Liu, Ewout Foppen, Cécile Tourrel-Cuzin, Ana Rodriguez Sanchez-Archidona, Etienne Delangre, Céline Cruciani-Guglielmacci, Stéphanie Pons, Uwe Maskos, Bernard Thorens, Christophe Magnan, Jamileh Movassat, Kamel Maouche

Biomolecules. 2020 Jul; 10(7): 1057. Published online 2020 Jul 16. doi: 10.3390/biom10071057

PMCID:: PMC7408520

Abstract Article PDF–3.6M

Select item 727452512.

Microbial bile acid metabolites modulate gut RORγ⁺ regulatory T cell homeostasis

Xinyang Song, Ximei Sun, Sungwhan F. Oh, Meng Wu, Yanbo Zhang, Wen Zheng, Naama Geva-Zatorsky, Ray Jupp, Diane Mathis, Christophe Benoist, Dennis L. Kasper

Nature. Author manuscript; available in PMC 2020 Jun 5.

Published in final edited form as: Nature. 2020 Jan; 577(7790): 410–415. Published online 2019 Dec 25. doi: 10.1038/s41586-019-1865-0

PMCID:: PMC7274525

Abstract Article PDF–5.1M

Select item 694926313.

Prox1-positive cells monitor and sustain the murine intestinal epithelial cholinergic niche

Moritz Middelhoff, Henrik Nienhüser, Giovanni Valenti, H. Carlo Maurer, Yoku Hayakawa, Ryota Takahashi, Woosook Kim, Zhengyu Jiang, Ermanno Malagola, Krystle Cuti, Yagnesh Tailor, Leah B. Zamechek, Bernhard W. Renz, Michael Quante, Kelley S. Yan, Timothy C. Wang

Nat Commun. 2020; 11: 111. Published online 2020 Jan 8. doi: 10.1038/s41467-019-13850-7

PMCID:: PMC6949263

Abstract Article PDF–9.1M

Select item 675842714.

Mice Lacking M₂ and M₃ Muscarinic Acetylcholine Receptors Are Devoid of Cholinergic Smooth Muscle Contractions But Still Viable

Minoru Matsui, Daisuke Motomura, Toru Fujikawa, Jian Jiang, Shin-ichi Takahashi, Toshiya Manabe, Makoto M. Taketo

J Neurosci. 2002 Dec 15; 22(24): 10627–10632. doi: 10.1523/JNEUROSCI.22-24-10627.2002

PMCID:: PMC6758427

Abstract Article PDF–318K

Select item 675813515.

Multiple Muscarinic Acetylcholine Receptor Subtypes Modulate Striatal Dopamine Release, as Studied with M₁–M₅ Muscarinic Receptor Knock-Out Mice

Weilie Zhang, Masahisa Yamada, Jesus Gomeza, Anthony S. Basile, Jürgen Wess

J Neurosci. 2002 Aug 1; 22(15): 6347–6352. doi: 10.1523/JNEUROSCI.22-15-06347.2002

PMCID:: PMC6758135

Abstract Article PDF–162K

Select item 674490216.

Allosteric modulation of β-cell M₃ muscarinic acetylcholine receptors greatly improves glucose homeostasis in lean and obese mice

Lu Zhu, Mario Rossi, Amanda Cohen, Jonathan Pham, Hongchao Zheng, Diptadip Dattaroy, Taro Mukaibo, James E. Melvin, Jennifer L. Langel, Samer Hattar, Franz M. Matschinsky, Daniel H. Appella, Nicolai M. Doliba, Jürgen Wess

Proc Natl Acad Sci U S A. 2019 Sep 10; 116(37): 18684–18690. Published online 2019 Aug 26. doi: 10.1073/pnas.1904943116

PMCID:: PMC6744902

Abstract Article PDF–1.1M

Select item 672565617.

Modulation of Synaptic Plasticity by Physiological Activation of M₁ Muscarinic Acetylcholine Receptors in the Mouse Hippocampus

Toru Shinoe, Minoru Matsui, Makoto M. Taketo, Toshiya Manabe

J Neurosci. 2005 Nov 30; 25(48): 11194–11200. doi: 10.1523/JNEUROSCI.2338-05.2005

PMCID:: PMC6725656

Abstract Article PDF–657K

Select item 660193118.

Sustained G_q-Protein Signaling Disrupts Striatal Circuits via JNK

Luigi Bellocchio, Andrea Ruiz-Calvo, Anna Chiarlone, Magali Cabanas, Eva Resel, Jean-René Cazalets, Cristina Blázquez, Yoon H. Cho, Ismael Galve-Roperh, Manuel Guzmán

J Neurosci. 2016 Oct 12; 36(41): 10611–10624. doi: 10.1523/JNEUROSCI.1192-16.2016

PMCID:: PMC6601931

Abstract Article PDF–3.9M

Select item 643568019.

The M₁ muscarinic acetylcholine receptor subtype is important for retinal neuron survival in aging mice

Panagiotis Laspas, Mayagozel B. Zhutdieva, Christoph Brochhausen, Aytan Musayeva, Jenia Kouchek Zadeh, Norbert Pfeiffer, Ning Xia, Huige Li, Juergen Wess, Adrian Gericke

Sci Rep. 2019; 9: 5222. Published online 2019 Mar 26. doi: 10.1038/s41598-019-41425-5

PMCID:: PMC6435680

Abstract Article PDF–8.2M

Select item 613771820.

Muscarinic receptors 2 and 5 regulate bitter response of urethral brush cells via negative feedback

Klaus Deckmann, Amir Rafiq, Christian Erdmann, Christian Illig, Melanie Durschnabel, Jürgen Wess, Wolfgang Weidner, Thomas Bschleipfer, Wolfgang Kummer

FASEB J. 2018 Jun; 32(6): 2903–2910. Published online 2018 Jan 17. doi: 10.1096/fj.201700582R

PMCID:: PMC6137718

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