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Select item 112339081.

Cocaine disrupts action flexibility via glucocorticoid receptors

Michelle K. Sequeira, Kathryn M. Stachowicz, Esther H. Seo, Sophie T. Yount, Shannon L. Gourley

iScience. 2024 Jul 19; 27(7): 110148. Published online 2024 May 28. doi: 10.1016/j.isci.2024.110148

PMCID:: PMC11233908

Abstract Article PDF–4.1M

Select item 111807762.

Deficiency of glucocorticoid receptor in bone marrow adipocytes has mild effects on bone and hematopoiesis but does not influence expansion of marrow adiposity with caloric restriction

Rebecca L. Schill, Jack Visser, Mariah L. Ashby, Ziru Li, Kenneth T. Lewis, Antonio Morales-Hernandez, Keegan S. Hoose, Jessica N. Maung, Romina M. Uranga, Hadla Hariri, Isabel D. K. Hermsmeyer, Hiroyuki Mori, Ormond A. MacDougald

Front Endocrinol (Lausanne) 2024; 15: 1397081. Published online 2024 Jun 3. doi: 10.3389/fendo.2024.1397081

PMCID:: PMC11180776

Abstract Article PDF–7.8M

Select item 111390353.

The glucocorticoid receptor acts locally to protect dystrophic muscle and heart during disease

Trinitee Oliver, Nhu Y. Nguyen, Christopher B. Tully, Nikki M. McCormack, Christina M. Sun, Alyson A. Fiorillo, Christopher R. Heier

Dis Model Mech. 2024 May 1; 17(5): dmm050397. Published online 2024 May 21. doi: 10.1242/dmm.050397

PMCID:: PMC11139035

Abstract Article

Select item 110818634.

Cardiac GR Mediates the Diurnal Rhythm in Ventricular Arrhythmia Susceptibility

Roman Tikhomirov, Robert H. Oakley, Cali Anderson, Yirong Xiang, Sami Al-Othman, Matthew Smith, Sana Yaar, Eleonora Torre, Jianying Li, Leslie R. Wilson, David R. Goulding, Ian Donaldson, Erika Harno, Luca Soattin, Holly A. Shiels, Gwilym M. Morris, Henggui Zhang, Mark R. Boyett, John A. Cidlowski, Pietro Mesirca, Matteo E. Mangoni, Alicia D’Souza

Circ Res. 2024 May 10; 134(10): 1306–1326. Published online 2024 Mar 27. doi: 10.1161/CIRCRESAHA.123.323464

PMCID:: PMC11081863

Abstract Article PDF–6.9M

Select item 109854755.

Glucocorticoid Receptor (GR) Activation Is Associated with Increased cAMP/PKA Signaling in Castration-Resistant Prostate Cancer

Lynda Bennett, Praveen Kumar Jaiswal, Ryan V. Harkless, Tiha M. Long, Ning Gao, Brianna Vandenburg, Phillip Selman, Ishrat Durdana, Ricardo R. Lastra, Donald Vander Griend, Remi Adelaiye-Ogala, Russell Z. Szmulewitz, Suzanne D. Conzen

Mol Cancer Ther. 2024 Apr 2; 23(4): 552–563. Published online 2023 Nov 29. doi: 10.1158/1535-7163.MCT-22-0479

PMCID:: PMC10985475

Abstract Article PDF–24M

Select item 108095066.

The glucocorticoid receptor as a master regulator of the Müller cell response to diabetic conditions in mice

Anna M. Pfaller, Lew Kaplan, Madalena Carido, Felix Grassmann, Nundehui Díaz-Lezama, Farhad Ghaseminejad, Kirsten A. Wunderlich, Sarah Glänzer, Oliver Bludau, Thomas Pannicke, Bernhard H. F. Weber, Susanne F. Koch, Boyan Bonev, Stefanie M. Hauck, Antje Grosche

J Neuroinflammation. 2024; 21: 33. Published online 2024 Jan 25. doi: 10.1186/s12974-024-03021-x

PMCID:: PMC10809506

Abstract Article PDF–16M

Select item 106405487.

HSP47 levels determine the degree of body adiposity

Jihoon Shin, Shinichiro Toyoda, Yosuke Okuno, Reiko Hayashi, Shigeki Nishitani, Toshiharu Onodera, Haruyo Sakamoto, Shinya Ito, Sachiko Kobayashi, Hirofumi Nagao, Shunbun Kita, Michio Otsuki, Atsunori Fukuhara, Kazuhiro Nagata, Iichiro Shimomura

Nat Commun. 2023; 14: 7319. Published online 2023 Nov 11. doi: 10.1038/s41467-023-43080-x

PMCID:: PMC10640548

Abstract Article PDF–4.6M

Select item 106174128.

Impaired glucocorticoid receptor function attenuates herpes simplex virus 1 production during explant-induced reactivation from latency in female mice

Kelly S. Harrison, Nishani Wijesekera, Anastasia G. J. Robinson, Vanessa C. Santos, Robert H. Oakley, John A. Cidlowski, Clinton Jones

J Virol. 2023 Oct; 97(10): e01305-23. Published online 2023 Oct 12. doi: 10.1128/jvi.01305-23

PMCID:: PMC10617412

Abstract Article PDF–2.4M

Select item 104711739.

Blood-derived lysophospholipid sustains hepatic phospholipids and fat storage necessary for hepatoprotection in overnutrition

Cheen Fei Chin, Dwight L.A. Galam, Liang Gao, Bryan C. Tan, Bernice H. Wong, Geok-Lin Chua, Randy Y.J. Loke, Yen Ching Lim, Markus R. Wenk, Miao-Shan Lim, Wei-Qiang Leow, George B.B. Goh, Federico Torta, David L. Silver

J Clin Invest. 2023 Sep 1; 133(17): e171267. Published online 2023 Sep 1. doi: 10.1172/JCI171267

PMCID:: PMC10471173

Abstract Article PDF–17M

Select item 1039276210.

NR3C1/Glucocorticoid receptor activation promotes pancreatic β-cell autophagy overload in response to glucolipotoxicity

Tijun Wu, Yixue Shao, Xirui Li, Tao Wu, Ling Yu, Jin Liang, Yaru Zhang, Jiahui Wang, Tong Sun, Yunxia Zhu, Xiaoai Chang, Shusen Wang, Fang Chen, Xiao Han

Autophagy. 2023; 19(9): 2538–2557. Published online 2023 Apr 20. doi: 10.1080/15548627.2023.2200625

PMCID:: PMC10392762

Abstract Article PDF–6.8M

Select item 1020581011.

Adolescent stress impairs postpartum social behavior via anterior insula-prelimbic pathway in mice

Kyohei Kin, Jose Francis-Oliveira, Shin-ichi Kano, Minae Niwa

Nat Commun. 2023; 14: 2975. Published online 2023 May 23. doi: 10.1038/s41467-023-38799-6

PMCID:: PMC10205810

Abstract Article PDF–9.2M

Select item 1011911212.

Glucocorticoid activation of anti-inflammatory macrophages protects against insulin resistance

Giorgio Caratti, Ulrich Stifel, Bozhena Caratti, Ali J. M. Jamil, Kyoung-Jin Chung, Michael Kiehntopf, Markus H. Gräler, Matthias Blüher, Alexander Rauch, Jan P. Tuckermann

Nat Commun. 2023; 14: 2271. Published online 2023 Apr 20. doi: 10.1038/s41467-023-37831-z

PMCID:: PMC10119112

Abstract Article PDF–3.5M

Select item 1005542713.

Hippocampal glucocorticoid receptors modulate status epilepticus severity

Kimberly L. Kraus, Nawshaba Nawreen, Christin M. Godale, Arihant P. Chordia, Ben Packard, Candi L. LaSarge, James P. Herman, Steve C. Danzer

Neurobiol Dis. Author manuscript; available in PMC 2023 Mar 29.

Published in final edited form as: Neurobiol Dis. 2023 Mar; 178: 106014. Published online 2023 Jan 23. doi: 10.1016/j.nbd.2023.106014

PMCID:: PMC10055427

Abstract Article PDF–1.0M

Select item 1003496214.

Genetic deletion of the glucocorticoid receptor in Cx₃cr1⁺ myeloid cells is neuroprotective and improves motor recovery after spinal cord injury

Kathryn M. Madalena, Faith H. Brennan, Phillip G. Popovich

Exp Neurol. Author manuscript; available in PMC 2023 Mar 23.

Published in final edited form as: Exp Neurol. 2022 Sep; 355: 114114. Published online 2022 May 11. doi: 10.1016/j.expneurol.2022.114114

PMCID:: PMC10034962

Abstract Article PDF–3.9M

Select item 998360915.

Acute deletion of the central MR/GR steroid receptor correlates with changes in LTP, auditory neural gain, and GC-A cGMP signaling

Dila Calis, Morgan Hess, Philine Marchetta, Wibke Singer, Julian Modro, Ellis Nelissen, Jos Prickaerts, Peter Sandner, Robert Lukowski, Peter Ruth, Marlies Knipper, Lukas Rüttiger

Front Mol Neurosci. 2023; 16: 1017761. Published online 2023 Feb 17. doi: 10.3389/fnmol.2023.1017761

PMCID:: PMC9983609

Abstract Article PDF–2.0M

Select item 996155116.

Conditional Ablation of Glucocorticoid and Mineralocorticoid Receptors from Cochlear Supporting Cells Reveals Their Differential Roles for Hearing Sensitivity and Dynamics of Recovery from Noise-Induced Hearing Loss

Charles C. Barnes, Kathleen T. Yee, Douglas E. Vetter

Int J Mol Sci. 2023 Feb; 24(4): 3320. Published online 2023 Feb 7. doi: 10.3390/ijms24043320

PMCID:: PMC9961551

Abstract Article PDF–3.4M

Select item 991440817.

T Cell Energy Metabolism Is a Target of Glucocorticoids in Mice, Healthy Humans, and MS Patients

Leonie Meyer-Heemsoth, Katja Mitschke, Jasmina Bier, Konstantin Schütz, Andreas Villunger, Tobias J. Legler, Martin S. Weber, Fred Lühder, Holger M. Reichardt

Cells. 2023 Feb; 12(3): 450. Published online 2023 Jan 30. doi: 10.3390/cells12030450

PMCID:: PMC9914408

Abstract Article PDF–4.7M

Select item 988950218.

Mature B cells and mesenchymal stem cells control emergency myelopoiesis

Vivian Y Lim, Xing Feng, Runfeng Miao, Sandra Zehentmeier, Nathan Ewing-Crystal, Moonyoung Lee, Alexei V Tumanov, Ji Eun Oh, Akiko Iwasaki, Andrew Wang, Jungmin Choi, João P Pereira

Life Sci Alliance. 2023 Apr; 6(4): e202301924. Published online 2023 Jan 30. doi: 10.26508/lsa.202301924