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Select item 114326631.

Synergistic Effect between the APOE ε4 Allele with Genetic Variants of GSK3B and MAPT: Differential Profile between Refractory Epilepsy and Alzheimer Disease

Danira Toral-Rios, Pavel Pichardo-Rojas, Elizabeth Ruiz-Sánchez, Óscar Rosas-Carrasco, Rosa Carvajal-García, Dey Carol Gálvez-Coutiño, Nancy Lucero Martínez-Rodríguez, Ana Daniela Rubio-Chávez, Myr Alcántara-Flores, Arely López-Ramírez, Alma Rosa Martínez-Rosas, Ángel Alberto Ruiz-Chow, Mario Alonso-Vanegas, Victoria Campos-Peña

Int J Mol Sci. 2024 Sep; 25(18): 10228. Published online 2024 Sep 23. doi: 10.3390/ijms251810228

PMCID:: PMC11432663

Abstract Article PDF–2.1M

Select item 112963412.

A specific phosphorylation-dependent conformational switch in SARS-CoV-2 nucleocapsid protein inhibits RNA binding

Maiia Botova, Aldo R. Camacho-Zarco, Jacqueline Tognetti, Luiza Mamigonian Bessa, Serafima Guseva, Emmi Mikkola, Nicola Salvi, Damien Maurin, Torsten Herrmann, Martin Blackledge

Sci Adv. 2024 Aug 2; 10(31): eaax2323. Published online 2024 Aug 2. doi: 10.1126/sciadv.aax2323

PMCID:: PMC11296341

Abstract Article PDF–5.4M

Select item 112816613.

Comparative Proteomics and Interactome Analysis of the SARS-CoV-2 Nucleocapsid Protein in Human and Bat Cell Lines

Stuart D. Armstrong, Covadonga Alonso, Isabel Garcia-Dorival

Viruses. 2024 Jul; 16(7): 1117. Published online 2024 Jul 11. doi: 10.3390/v16071117

PMCID:: PMC11281661

Abstract Article PDF–1.9M

Select item 112154924.

GSK3: A potential target and pending issues for treatment of Alzheimer's disease

Jiahui Zhao, Mengying Wei, Minsong Guo, Mengyao Wang, Hongxia Niu, Tengfei Xu, Yuan Zhou

CNS Neurosci Ther. 2024 Jul; 30(7): e14818. Published online 2024 Jul 1. doi: 10.1111/cns.14818

PMCID:: PMC11215492

Abstract Article PDF–3.5M

Select item 112099355.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111599196.

Involvement of Pin1 induction in epithelial–mesenchymal transition of tamoxifen‐resistant breast cancer cells

Mi Ra Kim, Hoo‐Kyun Choi, Kyoung Bin Cho, Hyung Sik Kim, Keon Wook Kang

Cancer Sci. 2009 Oct; 100(10): 1834–1841. Published online 2009 Jun 24. doi: 10.1111/j.1349-7006.2009.01260.x

PMCID:: PMC11159919

Abstract Article PDF–1.5M

Select item 111481847.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 111056598.

Degradation of the mitochondrial complex I assembly factor TMEM126B under chronic hypoxia

Dominik C. Fuhrmann, Ilka Wittig, Stefan Dröse, Tobias Schmid, Nathalie Dehne, Bernhard Brüne

Cell Mol Life Sci. 2018 Aug; 75(16): 3051–3067. Published online 2018 Feb 20. doi: 10.1007/s00018-018-2779-y

PMCID:: PMC11105659

Abstract Article PDF–4.5M

Select item 110399389.

Association of glycogen synthase kinase-3β with cognitive impairment in type 2 diabetes patients: a six-year follow-up study

Wei Wei, Pan Xu, Li Li, Hong Mao, Na Li, Xiao-qing Wang, Li Wang, Zhi-peng Xu, Shi Zhao

Front Endocrinol (Lausanne) 2024; 15: 1386773. Published online 2024 Apr 10. doi: 10.3389/fendo.2024.1386773

PMCID:: PMC11039938

Abstract Article PDF–1.1M

Select item 1098144610.

NLRP3 Inflammasome Priming in the Retina of Diabetic Mice Requires REDD1-Dependent Activation of GSK3β

Christopher M. McCurry, Siddharth Sunilkumar, Sandeep M. Subrahmanian, Esma I. Yerlikaya, Allyson L. Toro, Ashley M. VanCleave, Shaunaci A. Stevens, Alistair J. Barber, Jeffery M. Sundstrom, Michael D. Dennis

Invest Ophthalmol Vis Sci. 2024 Mar; 65(3): 34. Published online 2024 Mar 28. doi: 10.1167/iovs.65.3.34

PMCID:: PMC10981446

Abstract Article PDF–2.5M

Select item 1080930511.

GSK‐3β activation mediates apolipoprotein E4‐associated cognitive impairment in type 2 diabetes mellitus: A multicenter, cross‐sectional study

Yang Gao, Haitao Yu, Yanchao Liu, Zhipeng Xu, Benrong He, Honghai Liu, Yuying Wang, Yao Zhang, Yi Liang, Ying Yang, Jie Zheng, Jian‐Zhi Wang

J Diabetes. 2024 Jan; 16(1): e13470. Published online 2023 Sep 12. doi: 10.1111/1753-0407.13470

PMCID:: PMC10809305

Abstract Article PDF–2.0M

Select item 1079497312.

GSK-3β as a Potential Coordinator of Anabolic and Catabolic Pathways in Hepatitis C Virus Insulin Resistance

Gokul C. Das, F. Blaine Hollinger

Intervirology. 2024 Jan-Dec; 67(1): 6–18. Published online 2023 Dec 15. doi: 10.1159/000535787

PMCID:: PMC10794973

Abstract Article

Select item 1071135013.

NRF1 knockdown alleviates lipopolysaccharide-induced pulmonary inflammatory injury by upregulating DKK3 and inhibiting the GSK-3β/β-catenin pathway

Le Kang, Xinhua Wang, Jianfang Wang, Jing Guo, Wang Zhang, Ruirui Lei

Clin Exp Immunol. 2023 Oct; 214(1): 120–129. Published online 2023 Jul 4. doi: 10.1093/cei/uxad071

PMCID:: PMC10711350

Abstract Article PDF–5.8M

Select item 1068703214.

Phosphorylation of USP27X by GSK3β maintains the stability and oncogenic functions of CBX2

Yushu Xing, Jirimu Ba-tu, Chongyang Dong, Xiaodong Cao, Bing Li, Xin Jia, Yu Juan, Xiaojie Lv, Huiwen Zhang, Na Qin, Wuri Han, Dongfeng Wang, Xiao Qi, Yutong Wang, Xulu Hao, Shuang Zhang, Xiaoli Du, Huanyun Wang, Minjie Wang

Cell Death Dis. 2023 Nov; 14(11): 782. Published online 2023 Nov 29. doi: 10.1038/s41419-023-06304-y

PMCID:: PMC10687032

Abstract Article PDF–4.9M

Select item 1067987915.

FUNDC2, a mitochondrial outer membrane protein, mediates triple-negative breast cancer progression via the AKT/GSK3β/GLI1 pathway: FUNDC2 mediates TNBC progression via the AKT/GSK3β/GLI1 pathway

Liyang Yin, Renxian Cao, Zhuoqing Liu, Gang Luo, Yu Li, Xiaolong Zhou, Xiguang Chen, Ying Wu, Jun He, Xuyu Zu, Yingying Shen

Acta Biochim Biophys Sin (Shanghai) 2023 Nov 25; 55(11): 1770–1783. Published online 2023 Sep 11. doi: 10.3724/abbs.2023142

PMCID:: PMC10679879

Abstract Article PDF–4.0M

Select item 1065198516.

Interferon‐γ inducible protein 30 promotes the epithelial–mesenchymal transition‐like phenotype and chemoresistance by activating EGFR/AKT/GSK3β/β‐catenin pathway in glioma

Ying Chen, Hui Xu, Pei Yu, Qing Wang, Shenggang Li, Fufu Ji, Chunwang Wu, Qing Lan

CNS Neurosci Ther. 2023 Dec; 29(12): 4124–4138. Published online 2023 Jul 5. doi: 10.1111/cns.14334

PMCID:: PMC10651985

Abstract Article PDF–8.7M

Select item 1064767417.

Transcriptional Regulation of the Human 5-HT1A Receptor Gene by Lithium: Role of Deaf1 and GSK3β

Emerson F. Harkin, Georges Nasrallah, Brice Le François, Paul R. Albert

Int J Mol Sci. 2023 Nov; 24(21): 15620. Published online 2023 Oct 26. doi: 10.3390/ijms242115620

PMCID:: PMC10647674

Abstract Article PDF–2.4M

Select item 1063781618.

PCMT1 regulates the migration, invasion, and apoptosis of prostate cancer through modulating the PI3K/AKT/GSK-3β pathway

Jiacheng Zhong, Chao Yuan, Lin Liu, Yang Du, Yumin Hui, Zhiyuan Chen, Changhui Diao, Rui Yang, Guiyong Liu, Xiuheng Liu

Aging (Albany NY) 2023 Oct 31; 15(20): 11654–11671. Published online 2023 Oct 27. doi: 10.18632/aging.205152

PMCID:: PMC10637816

Abstract Article PDF–2.0M

Select item 1052066019.

Targeting Squalene Epoxidase Confers Metabolic Vulnerability and Overcomes Chemoresistance in HNSCC

Xinyuan Zhao, Bing Guo, Wenjuan Sun, Jinhua Yu, Li Cui

Adv Sci (Weinh) 2023 Sep; 10(27): 2206878. Published online 2023 Jul 25. doi: 10.1002/advs.202206878

PMCID:: PMC10520660

Abstract Article PDF–6.8M

Select item 1040743220.

REDD1-dependent GSK3β dephosphorylation promotes NF-κB activation and macrophage infiltration in the retina of diabetic mice

Siddharth Sunilkumar, Ashley M. VanCleave, Christopher M. McCurry, Allyson L. Toro, Shaunaci A. Stevens, Scot R. Kimball, Michael D. Dennis

J Biol Chem. 2023 Aug; 299(8): 104991. Published online 2023 Jun 29. doi: 10.1016/j.jbc.2023.104991

PMCID:: PMC10407432

Abstract Article PDF–1.7M

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