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Items: 1 to 20 of 63

1.
Single-nucleus RNA-sequencing reveals NRF1/NFE2L1 as a key factor determining the thermogenesis and cellular heterogeneity and dynamics of brown adipose tissues in mice
Wei Shen, Suping Ren, Yongyong Hou, Zhuo Zuo, Shengnan Liu, Zhiyuan Liu, Jingqi Fu, Huihui Wang, Bei Yang, Rui Zhao, Yanyan Chen, Masayuki Yamamoto, Yuanyuan Xu, Qiang Zhang, Jingbo Pi
Redox Biol. 2023 Nov; 67: 102879. Published online 2023 Sep 11. doi: 10.1016/j.redox.2023.102879
PMCID:
PMC10511808
AbstractArticlePDF–15M
2.
HDL functionality is dependent on hepatocyte stress defense factors Nrf1 and Nrf2
Michael J. Trites, Brynne M. Stebbings, Hiroyuki Aoki, Sadhna Phanse, May G. Akl, Lei Li, Mohan Babu, Scott B. Widenmaier
Front Physiol. 2023; 14: 1212785. Published online 2023 Jul 12. doi: 10.3389/fphys.2023.1212785
PMCID:
PMC10369849
AbstractArticlePDF–2.6M
3.
Overexpression of Nfe2l1 increases proteasome activity and delays vision loss in a preclinical model of human blindness
Yixiao Wang, Aaron Snell, Frank M. Dyka, Elizabeth R. Colvin, Cristhian Ildefonso, John D. Ash, Ekaterina S. Lobanova
Sci Adv. 2023 Jul; 9(28): eadd5479. Published online 2023 Jul 14. doi: 10.1126/sciadv.add5479
PMCID:
PMC10348684
AbstractArticlePDF–2.1M
4.
Induction of Herpud1 expression by ER stress is regulated by Nrf1
Daniel V. Ho, Jefferson Y. Chan
FEBS Lett. Author manuscript; available in PMC 2023 Apr 10.
Published in final edited form as: FEBS Lett. 2015 Feb 27; 589(5): 615–620. Published online 2015 Jan 28. doi: 10.1016/j.febslet.2015.01.026
PMCID:
PMC10084809
AbstractArticlePDF–2.0M
5.
Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice
Esteban Salazar-Petres, Daniela Pereira-Carvalho, Jorge Lopez-Tello, Amanda Nancy Sferruzzi-Perri
Biol Reprod. 2022 Jun; 106(6): 1292–1311. Published online 2022 Mar 16. doi: 10.1093/biolre/ioac056
PMCID:
PMC9327737
AbstractArticlePDF–3.0M
6.
NFE2L1-mediated proteasome function protects from ferroptosis
Stefan Kotschi, Anna Jung, Nienke Willemsen, Anahita Ofoghi, Bettina Proneth, Marcus Conrad, Alexander Bartelt
Mol Metab. 2022 Mar; 57: 101436. Published online 2022 Jan 6. doi: 10.1016/j.molmet.2022.101436
PMCID:
PMC8814388
AbstractArticlePDF–2.1M
7.
NRF1 Association with AUTS2-Polycomb Mediates Specific Gene Activation in the Brain
Sanxiong Liu, Kimberly A. Aldinger, Chi Vicky Cheng, Takae Kiyama, Mitali Dave, Hanna K. McNamara, Wukui Zhao, James M. Stafford, Nicolas Descostes, Pedro Lee, Stefano G. Caraffi, Ivan Ivanovski, Edoardo Errichiello, Christiane Zweier, Orsetta Zuffardi, Michael Schneider, Antigone S. Papavasiliou, M. Scott Perry, Jennifer Humberson, Megan T. Cho, Astrid Weber, Andrew Swale, Tudor C. Badea, Chai-An Mao, Livia Garavelli, William B. Dobyns, Danny Reinberg
Mol Cell. Author manuscript; available in PMC 2022 Nov 18.
Published in final edited form as: Mol Cell. 2021 Nov 18; 81(22): 4663–4676.e8. Published online 2021 Oct 11. doi: 10.1016/j.molcel.2021.09.020
Correction in:
Mol Cell. 2021 Nov 18; 81(22): 4757.
PMCID:
PMC8604784
AbstractArticlePDF–2.8M
8.
Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance
Miao Cui, Ayhan Atmanli, Maria Gabriela Morales, Wei Tan, Kenian Chen, Xue Xiao, Lin Xu, Ning Liu, Rhonda Bassel-Duby, Eric N. Olson
Nat Commun. 2021; 12: 5270. Published online 2021 Sep 6. doi: 10.1038/s41467-021-25653-w
PMCID:
PMC8421386
AbstractArticlePDF–4.6M
9.
The roles of NFE2L1 in adipocytes: Structural and mechanistic insight from cell and mouse models
Suping Ren, Yiying Bian, Yongyong Hou, Zhendi Wang, Zhuo Zuo, Zhiyuan Liu, Yue Teng, Jingqi Fu, Huihui Wang, Yuanyuan Xu, Qiang Zhang, Yanyan Chen, Jingbo Pi
Redox Biol. 2021 Aug; 44: 102015. Published online 2021 May 24. doi: 10.1016/j.redox.2021.102015
PMCID:
PMC8170497
AbstractArticlePDF–2.3M
10.
Cardiac expression of HMOX1 and PGF in sickle cell mice and haem-treated wild type mice dominates organ expression profiles via Nrf2 (Nfe2l2)
Oluwabukola T. Gbotosho, Samit Ghosh, Maria G. Kapetanaki, Yu Lin, Frances Weidert, Grant C. Bullock, Solomon F. Ofori-Acquah, Gregory J. Kato
Br J Haematol. Author manuscript; available in PMC 2021 Mar 29.
Published in final edited form as: Br J Haematol. 2019 Dec; 187(5): 666–675. Published online 2019 Aug 6. doi: 10.1111/bjh.16129
PMCID:
PMC8007233
AbstractArticlePDF–594K
11.
TRIM59 expression is regulated by Sp1 and Nrf1 in LPS-activated macrophages through JNK signaling pathway
Yanying An, Yuqi Ni, Zhihao Xu, Shuizhen Shi, Jiashu He, Yu Liu, Ke-Yu Deng, Mingui Fu, Meixiu Jiang, Hong-Bo Xin
Cell Signal. Author manuscript; available in PMC 2020 Dec 30.
Published in final edited form as: Cell Signal. 2020 Mar; 67: 109522. Published online 2019 Dec 25. doi: 10.1016/j.cellsig.2019.109522
PMCID:
PMC7773022
AbstractArticlePDF–2.0M
12.
Synergism and Antagonism of Two Distinct, but Confused, Nrf1 Factors in Integral Regulation of the Nuclear-to-Mitochondrial Respiratory and Antioxidant Transcription Networks
Shuwei Zhang, Yangxu Deng, Yuancai Xiang, Shaofan Hu, Lu Qiu, Yiguo Zhang
Oxid Med Cell Longev. 2020; 2020: 5097109. Published online 2020 Nov 16. doi: 10.1155/2020/5097109
PMCID:
PMC7744186
AbstractArticlePDF–6.1M
13.
Heme Induces IL-6 and Cardiac Hypertrophy Genes Transcripts in Sickle Cell Mice
Oluwabukola T. Gbotosho, Maria G. Kapetanaki, Samit Ghosh, Flordeliza S. Villanueva, Solomon F. Ofori-Acquah, Gregory J. Kato
Front Immunol. 2020; 11: 1910. Published online 2020 Aug 21. doi: 10.3389/fimmu.2020.01910
PMCID:
PMC7473032
AbstractArticlePDF–607K
14.
Decreased levels of constitutive proteasomes in experimental autoimmune encephalomyelitis may be caused by a combination of subunit displacement and reduced Nfe2l1 expression
Kara L. Shanley, Che-Lin Hu, Oscar A. Bizzozero
J Neurochem. Author manuscript; available in PMC 2021 Mar 1.
Published in final edited form as: J Neurochem. 2020 Mar; 152(5): 585–601. Published online 2019 Dec 2. doi: 10.1111/jnc.14912
PMCID:
PMC7047544
AbstractArticlePDF–2.5M
15.
Long isoforms of NRF1 negatively regulate adipogenesis via suppression of PPARγ expression
Peng Xue, Yongyong Hou, Zhuo Zuo, Zhendi Wang, Suping Ren, Jian Dong, Jingqi Fu, Huihui Wang, Melvin E. Andersen, Qiang Zhang, Yuanyuan Xu, Jingbo Pi
Redox Biol. 2020 Feb; 30: 101414. Published online 2019 Dec 28. doi: 10.1016/j.redox.2019.101414
PMCID:
PMC6957832
AbstractArticlePDF–1.9M
16.
TCF11/Nrf1-Mediated Induction of Proteasome Expression Prevents Cytotoxicity by Rotenone
Franziska Sotzny, Eileen Schormann, Ina Kühlewindt, Annett Koch, Anja Brehm, Raphaela Goldbach-Mansky, Kate E. Gilling, Elke Krüger
Antioxid Redox Signal. 2016 Dec 1; 25(16): 870–885. Published online 2016 Dec 1. doi: 10.1089/ars.2015.6539
PMCID:
PMC6445217
AbstractArticlePDF–956K
17.
Nrf1-mediated transcriptional regulation of the proteasome requires a functional TIP60 complex
Janakiram R. Vangala, Senthil K. Radhakrishnan
J Biol Chem. 2019 Feb 8; 294(6): 2036–2045. Published online 2018 Dec 17. doi: 10.1074/jbc.RA118.006290
PMCID:
PMC6369275
AbstractArticlePDF–1.8M
18.
N-glycanase NGLY1 regulates mitochondrial homeostasis and inflammation through NRF1
Kun Yang, Ryan Huang, Haruhiko Fujihira, Tadashi Suzuki, Nan Yan
J Exp Med. 2018 Oct 1; 215(10): 2600–2616. doi: 10.1084/jem.20180783
PMCID:
PMC6170171
AbstractArticlePDF–3.7M
19.
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
Alexander Bartelt, Scott B. Widenmaier, Christian Schlein, Kornelia Johann, Renata L. S. Goncalves, Kosei Eguchi, Alexander W. Fischer, Günes Parlakgül, Nicole A. Snyder, Truc B. Nguyen, Oliver T. Bruns, Daniel Franke, Moungi G. Bawendi, Matthew D. Lynes, Luiz O. Leiria, Yu-Hua Tseng, Karen E. Inouye, Ana Paula Arruda, Gökhan S. Hotamisligil
Nat Med. Author manuscript; available in PMC 2018 Aug 5.
Published in final edited form as: Nat Med. 2018 Mar; 24(3): 292–303. Published online 2018 Feb 5. doi: 10.1038/nm.4481
PMCID:
PMC5839993
AbstractArticlePDF–1.2M
20.
A Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways
Liam Baird, Tadayuki Tsujita, Eri H. Kobayashi, Ryo Funayama, Takeshi Nagashima, Keiko Nakayama, Masayuki Yamamoto
Mol Cell Biol. 2017 Feb 15; 37(4): e00439-16. Prepublished online 2016 Dec 5. Published online 2017 Feb 1. doi: 10.1128/MCB.00439-16
PMCID:
PMC5288573
AbstractArticlePDF–1.8M

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