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Select item 111277681.

IL-22RA2 Is a SMAD7 Target Mediating the Alleviation of Dermatitis and Psoriatic Phenotypes in Mice

Yao Ke, Ben-Zheng Li, Khoa Nguyen, Donna Wang, Suyan Wang, Christian D. Young, Xiao-Jing Wang

J Invest Dermatol. Author manuscript; available in PMC 2024 May 25.

Published in final edited form as: J Invest Dermatol. 2023 Nov; 143(11): 2243–2254.e10. Published online 2023 May 19. doi: 10.1016/j.jid.2023.04.029

PMCID:: PMC11127768

Abstract Article PDF–2.3M

Select item 111137992.

Smad7 enhances ATM activity by facilitating the interaction between ATM and Mre11-Rad50-Nbs1 complex in DNA double-strand break repair

Sujin Park, Jin Muk Kang, Staci Jakyong Kim, Hyojung Kim, Suntaek Hong, Young Jae Lee, Seong-Jin Kim

Cell Mol Life Sci. 2015 Feb; 72(3): 583–596. Published online 2014 Jul 26. doi: 10.1007/s00018-014-1687-z

PMCID:: PMC11113799

Abstract Article PDF–5.9M

Select item 103756363.

Smad7 in the hippocampus contributes to memory impairment in aged mice after anesthesia and surgery

Changliang Liu, Jiahui Wu, Ming Li, Rui Gao, Xueying Zhang, Shixin Ye-Lehmann, Jiangning Song, Tao Zhu, Chan Chen

J Neuroinflammation. 2023; 20: 175. Published online 2023 Jul 28. doi: 10.1186/s12974-023-02849-z

PMCID:: PMC10375636

Abstract Article PDF–2.6M

Select item 101886354.

Astrocyte-derived exosomal lncRNA 4933431K23Rik modulates microglial phenotype and improves post-traumatic recovery via SMAD7 regulation

Xuejun He, Yimin Huang, Yuan Liu, Xincheng Zhang, Quanji Wang, Yanchao Liu, Xiaopeng Ma, Xiaobing Long, Yang Ruan, Hongxia Lei, Chao Gan, Xiaochuan Wang, Xin Zou, Bo Xiong, Kai Shu, Ting Lei, Huaqiu Zhang

Mol Ther. 2023 May 3; 31(5): 1313–1331. Published online 2023 Feb 3. doi: 10.1016/j.ymthe.2023.01.031

PMCID:: PMC10188635

Abstract Article PDF–4.7M

Select item 101191215.

Topologically associating domain boundaries are required for normal genome function

Sudha Rajderkar, Iros Barozzi, Yiwen Zhu, Rong Hu, Yanxiao Zhang, Bin Li, Ana Alcaina Caro, Yoko Fukuda-Yuzawa, Guy Kelman, Adyam Akeza, Matthew J. Blow, Quan Pham, Anne N. Harrington, Janeth Godoy, Eman M. Meky, Kianna von Maydell, Riana D. Hunter, Jennifer A. Akiyama, Catherine S. Novak, Ingrid Plajzer-Frick, Veena Afzal, Stella Tran, Javier Lopez-Rios, Michael E. Talkowski, K. C. Kent Lloyd, Bing Ren, Diane E. Dickel, Axel Visel, Len A. Pennacchio

Commun Biol. 2023; 6: 435. Published online 2023 Apr 20. doi: 10.1038/s42003-023-04819-w

PMCID:: PMC10119121

Abstract Article PDF–3.2M

Select item 95612656.

LncRNA-Smad7 mediates cross-talk between Nodal/TGF-β and BMP signaling to regulate cell fate determination of pluripotent and multipotent cells

Xiaohui Kong, Kun Yan, Pujuan Deng, Haipeng Fu, Hongyao Sun, Wenze Huang, Shuangying Jiang, Junbiao Dai, Qiangfeng Cliff Zhang, Jun-jie Gogo Liu, Qiaoran Xi

Nucleic Acids Res. 2022 Oct 14; 50(18): 10526–10543. Published online 2022 Sep 22. doi: 10.1093/nar/gkac780

Correction in:: Nucleic Acids Res. 2023 Apr 11; 51(6): 2995.

PMCID:: PMC9561265

Abstract Article PDF–2.8M

Select item 94402557.

Hepatocyte-specific Prominin-1 protects against liver injury-induced fibrosis by stabilizing SMAD7

Hyun Lee, Dong-Min Yu, Myeong-Suk Bahn, Young-Jae Kwon, Min Jee Um, Seo Yeon Yoon, Ki-Tae Kim, Myoung-Woo Lee, Sung-Je Jo, Sungsoo Lee, Seung-Hoi Koo, Ki Hoon Jung, Jae-Seon Lee, Young-Gyu Ko

Exp Mol Med. 2022 Aug; 54(8): 1277–1289. Published online 2022 Aug 29. doi: 10.1038/s12276-022-00831-y

PMCID:: PMC9440255

Abstract Article PDF–6.8M

Select item 92161828.

The role of endogenous Smad7 in regulating macrophage phenotype following myocardial infarction

Jun Li, Ruoshui Li, Izabela Tuleta, Silvia C Hernandez, Claudio Humeres, Anis Hanna, Bijun Chen, Nikolaos G Frangogiannis

FASEB J. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: FASEB J. 2022 Jul; 36(7): e22400. doi: 10.1096/fj.202101956RR

PMCID:: PMC9216182

Abstract Article PDF–2.0M

Select item 88551569.

Molecular mechanism of the TGF-β/Smad7 signaling pathway in ulcerative colitis

Bingqing Bai, Huihui Li, Liang Han, Yongyu Mei, Cui Hu, Qiao Mei, Jianming Xu, Xiaochang Liu

Mol Med Rep. 2022 Apr; 25(4): 116. Published online 2022 Feb 7. doi: 10.3892/mmr.2022.12632

PMCID:: PMC8855156

Abstract Article PDF–3.0M

Select item 880333610.

Smad7 effects on TGF-β and ErbB2 restrain myofibroblast activation and protect from postinfarction heart failure

Claudio Humeres, Arti V. Shinde, Anis Hanna, Linda Alex, Silvia C. Hernández, Ruoshui Li, Bijun Chen, Simon J. Conway, Nikolaos G. Frangogiannis

J Clin Invest. 2022 Feb 1; 132(3): e146926. Published online 2022 Feb 1. doi: 10.1172/JCI146926

PMCID:: PMC8803336

Abstract Article PDF–15M

Select item 871407611.

SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning

Julie Gamart, Iros Barozzi, Frédéric Laurent, Robert Reinhardt, Laurène Ramos Martins, Thomas Oberholzer, Axel Visel, Rolf Zeller, Aimée Zuniga

Development. 2021 Dec 1; 148(23): dev200182. Published online 2021 Dec 3. doi: 10.1242/dev.200182

PMCID:: PMC8714076

Abstract Article

Select item 870872312.

Genome-Wide Analysis of Smad7-Mediated Transcription in Mouse Embryonic Stem Cells

Guohua Meng, Andrea Lauria, Mara Maldotti, Francesca Anselmi, Isabelle Laurence Polignano, Stefania Rapelli, Daniela Donna, Salvatore Oliviero

Int J Mol Sci. 2021 Dec; 22(24): 13598. Published online 2021 Dec 18. doi: 10.3390/ijms222413598

PMCID:: PMC8708723

Abstract Article PDF–3.5M

Select item 858425213.

Smad7 Deficiency in Myeloid Cells Does Not Affect Liver Injury, Inflammation or Fibrosis after Chronic CCl₄ Exposure in Mice

Ludmilla Unrau, Jessica Endig, Diane Goltz, Paulina Sprezyna, Hanna Ulrich, Julia Hagenstein, Bernd Geers, Karina Kaftan, Lukas Carl Heukamp, Gisa Tiegs, Linda Diehl

Int J Mol Sci. 2021 Nov; 22(21): 11575. Published online 2021 Oct 27. doi: 10.3390/ijms222111575

PMCID:: PMC8584252

Abstract Article PDF–2.5M

Select item 837130814.

Smad7 attenuates TGF-β-mediated aging-related hypofunction of submandibular glands

Minqi Hu, Wei Liu, Pingchuan Ma, Yingyi Wu, Honglin Li, Yi Men, Xiufa Tang, Lin Que, Yubin Cao, Chunjie Li

Exp Biol Med (Maywood) 2021 Jun; 246(11): 1269–1273. Published online 2021 Feb 27. doi: 10.1177/1535370221993430

PMCID:: PMC8371308

Abstract Article PDF–781K

Select item 831386315.

Srsf3 mediates alternative RNA splicing downstream of PDGFRα signaling in the facial mesenchyme

Brenna J. C. Dennison, Eric D. Larson, Rui Fu, Julia Mo, Katherine A. Fantauzzo

Development. 2021 Jul 15; 148(14): dev199448. Published online 2021 Jul 13. doi: 10.1242/dev.199448

PMCID:: PMC8313863

Abstract Article

Select item 824799116.

Quick validation of genetic quality for conditional alleles in mice

Hatsumi Nakata, Tomomi Hashimoto, Atsushi Yoshiki

Genes Cells. 2021 Apr; 26(4): 240–245. Published online 2021 Feb 26. doi: 10.1111/gtc.12834

PMCID:: PMC8247991

Abstract Article PDF–922K

Select item 822241717.

Overexpression of SMAD7 activates the YAP/NOTCH cascade and promotes liver carcinogenesis in mice and humans

Haichuan Wang, Xinhua Song, Haotian Liao, Pan Wang, Yi Zhang, Li Che, Jie Zhang, Yi Zhou, Antonio Cigliano, Cindy Ament, Daphne Superville, Silvia Ribback, Melissa Reeves, Giovanni M. Pes, Binyong Liang, Hong Wu, Matthias Evert, Diego F. Calvisi, Yong Zeng, Xin Chen

Hepatology. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: Hepatology. 2021 Jul; 74(1): 248–263. Published online 2021 Jun 15. doi: 10.1002/hep.31692

PMCID:: PMC8222417

Abstract Article PDF–3.3M

Select item 806918818.

Involvement of Smad7 in Inflammatory Diseases of the Gut and Colon Cancer

Edoardo Troncone, Irene Marafini, Carmine Stolfi, Giovanni Monteleone

Int J Mol Sci. 2021 Apr; 22(8): 3922. Published online 2021 Apr 10. doi: 10.3390/ijms22083922

PMCID:: PMC8069188

Abstract Article PDF–1021K

Select item 793877019.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 789053620.

HELIGMOSOMOIDES BAKERI INFECTION DECREASES SMAD7 EXPRESSION IN INTESTINAL CD4+ T CELLS WHICH ALLOWS TGFβ TO INDUCE IL10-PRODUCING REGULATORY T CELLS THAT BLOCK COLITIS

Long Hang, Sangeeta Kumar, Arthur M Blum, Joseph F Urban, Jr, Massimo C Fantini, Joel V Weinstock

J Immunol. Author manuscript; available in PMC 2021 Feb 18.

Published in final edited form as: J Immunol. 2019 Apr 15; 202(8): 2473–2481. Published online 2019 Mar 8. doi: 10.4049/jimmunol.1801392

PMCID:: PMC7890536

Abstract Article PDF–1.7M

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