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Items: 1 to 20 of 37

1.
The PP2A regulatory subunit PPP2R2A controls NAD+ biosynthesis to regulate T cell subset differentiation in systemic autoimmunity
Wenliang Pan, Maria G. Tsokos, Marc Scherlinger, Wei Li, George C. Tsokos
Cell Rep. Author manuscript; available in PMC 2024 Sep 20.
Published in final edited form as: Cell Rep. 2024 Jul 23; 43(7): 114379. Published online 2024 Jun 17. doi: 10.1016/j.celrep.2024.114379
PMCID:
PMC11414414
AbstractArticlePDF–2.7M
2.
PP2A-B55 phosphatase counteracts Ki-67-dependent chromosome individualization during mitosis
María Sanz-Flores, Miguel Ruiz-Torres, Cristina Aguirre-Portolés, Aicha El Bakkali, Beatriz Salvador-Barberó, Carolina Villarroya-Beltri, Sagrario Ortega, Diego Megías, Daniel W. Gerlich, Mónica Álvarez-Fernández, Marcos Malumbres
Cell Rep. 2024 Jul 23; 43(7): 114494. Published online 2024 Jul 13. doi: 10.1016/j.celrep.2024.114494
PMCID:
PMC11290319
AbstractArticle
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
5.
The regulatory subunit PPP2R2A of PP2A enhances Th1 and Th17 differentiation through activation of the GEF-H1/RhoA/ROCK signaling pathway
Wenliang Pan, Kamalpreet Nagpal, Abel Suárez-Fueyo, Andrew Ferretti, Nobuya Yoshida, Maria G. Tsokos, George C. Tsokos
J Immunol. Author manuscript; available in PMC 2021 Oct 15.
Published in final edited form as: J Immunol. 2021 Apr 15; 206(8): 1719–1728. Published online 2021 Mar 24. doi: 10.4049/jimmunol.2001266
PMCID:
PMC8026731
AbstractArticlePDF–1.0M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
B55α/PP2A limits endothelial cell apoptosis during vascular remodeling: a complementary approach to kill pathological vessels?
Manuel Ehling, Ward Celus, Rosa Martín-Pérez, Roser Alba-Rovira, Sander Willox, Giusy Di Conza, Massimiliano Mazzone
Circ Res. Author manuscript; available in PMC 2024 Sep 10.
Published in final edited form as: Circ Res. 2020 Aug 28; 127(6): 707–723. Published online 2020 Jun 12. doi: 10.1161/CIRCRESAHA.119.316071
PMCID:
PMC7616433
AbstractArticlePDF–4.3M
8.
Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
Nikita Panicker, Melody Coutman, Charley Lawlor-O’Neill, Richard G. S. Kahl, Séverine Roselli, Nicole M. Verrills
Front Cell Dev Biol. 2020; 8: 358. Published online 2020 Jun 5. doi: 10.3389/fcell.2020.00358
PMCID:
PMC7290052
AbstractArticlePDF–2.8M
9.
Integrin α5β1 regulates PP2A complex assembly through PDE4D in atherosclerosis
Sanguk Yun, Rui Hu, Melanie E. Schwaemmle, Alexander N. Scherer, Zhenwu Zhuang, Anthony J. Koleske, David C. Pallas, Martin A. Schwartz
J Clin Invest. 2019 Nov 1; 129(11): 4863–4874. Published online 2019 Oct 7. doi: 10.1172/JCI127692
PMCID:
PMC6819111
AbstractArticlePDF–7.9M
10.
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics
Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea
Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253
PMCID:
PMC6692770
AbstractArticlePDF–7.7M
11.
Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization
Darryl S. Watkins, Jason D. True, Amber L. Mosley, Anthony J. Baucum, II
Proteomes. 2018 Dec; 6(4): 53. Published online 2018 Dec 17. doi: 10.3390/proteomes6040053
Correction in:
Proteomes. 2019 Mar; 7(1): 7.
PMCID:
PMC6313900
AbstractArticlePDF–2.5M
12.
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells
Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch
Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262
PMCID:
PMC6244183
AbstractArticlePDF–753K
13.
RNA binding proteins co-localize with small tau inclusions in tauopathy
Brandon F. Maziuk, Daniel J. Apicco, Anna Lourdes Cruz, Lulu Jiang, Peter E. A. Ash, Edroaldo Lummertz da Rocha, Cheng Zhang, Wai Haung Yu, John Leszyk, Jose F. Abisambra, Hu Li, Benjamin Wolozin
Acta Neuropathol Commun. 2018; 6: 71. Published online 2018 Aug 1. doi: 10.1186/s40478-018-0574-5
PMCID:
PMC6069705
AbstractArticlePDF–5.5M
14.
Haplo-Insufficiency of the Insulin Receptor in the presence of a splice-site mutation in Ppp2r2a results in a novel di-genic mouse model of type 2 diabetes
Michelle Goldsworthy, Ying Bai, Chi-Ming Li, Huanying Ge, Edwin Lamas, Helen Hilton, Christopher T Esapa, Dan Baker, Will Baron, Todd Juan, Murielle M Véniant, David J Lloyd, Roger D Cox
Diabetes. Author manuscript; available in PMC 2018 May 11.
Published in final edited form as: Diabetes. 2016 May; 65(5): 1434–1446. Published online 2016 Feb 11. doi: 10.2337/db15-1276
PMCID:
PMC5947768
AbstractArticlePDF–1.9M
15.
Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins
Rolen M. Quadros, Hiromi Miura, Donald W. Harms, Hisako Akatsuka, Takehito Sato, Tomomi Aida, Ronald Redder, Guy P. Richardson, Yutaka Inagaki, Daisuke Sakai, Shannon M. Buckley, Parthasarathy Seshacharyulu, Surinder K. Batra, Mark A. Behlke, Sarah A. Zeiner, Ashley M. Jacobi, Yayoi Izu, Wallace B. Thoreson, Lisa D. Urness, Suzanne L. Mansour, Masato Ohtsuka, Channabasavaiah B. Gurumurthy
Genome Biol. 2017; 18: 92. Published online 2017 May 17. doi: 10.1186/s13059-017-1220-4
PMCID:
PMC5434640
AbstractArticlePDF–1.1M
16.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
17.
Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A
Pui-Mun Wong, Yan Feng, Junru Wang, Rong Shi, Xuejun Jiang
Nat Commun. 2015; 6: 8048. Published online 2015 Aug 27. doi: 10.1038/ncomms9048
PMCID:
PMC4552084
AbstractArticlePDF–4.6M
18.
The Central Role of EED in the Orchestration of Polycomb Group Complexes
Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan
Nat Commun. Author manuscript; available in PMC 2014 Jul 24.
Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127
PMCID:
PMC4073494
AbstractArticlePDF–2.1M
19.
Rab3Gap1 mediates exocytosis of Claudin-1 and tight junction formation during epidermal barrier acquisition
G. Youssef, L. Gerner, A.S. Naeem, O. Ralph, M. Ono, C.A. O’Neill, R.F.L. O’Shaughnessy
Dev Biol. 2013 Aug 15; 380(2): 274–285. doi: 10.1016/j.ydbio.2013.04.034
PMCID:
PMC3995087
AbstractArticle
20.
Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting
Christoph Biesemann, Mads Grønborg, Elisa Luquet, Sven P Wichert, Véronique Bernard, Simon R Bungers, Ben Cooper, Frédérique Varoqueaux, Liyi Li, Jennifer A Byrne, Henning Urlaub, Olaf Jahn, Nils Brose, Etienne Herzog
EMBO J. 2014 Jan 16; 33(2): 157–170. Published online 2014 Jan 10. doi: 10.1002/embj.201386120
PMCID:
PMC3989609
AbstractArticlePDF–2.8M

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