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Items: 1 to 20 of 56

1.
Hyperactivation of ATF4/TGF-β1 signaling contributes to the progressive cardiac fibrosis in Arrhythmogenic cardiomyopathy caused by DSG2 Variant
Baowei Zhang, Yizhang Wu, Chunjiang Zhou, Jiaxi Xie, Youming Zhang, Xingbo Yang, Jing Xiao, Dao Wu Wang, Congjia Shan, Xiujuan Zhou, Yaozu Xiang, Bing Yang
BMC Med. 2024; 22: 361. Published online 2024 Sep 4. doi: 10.1186/s12916-024-03593-8
PMCID:
PMC11373413
AbstractArticlePDF–18M
2.
Structure and function of desmosomal proteins and their role in development and disease
O. Huber
Cell Mol Life Sci. 2003 Sep; 60(9): 1872–1890. doi: 10.1007/s00018-003-3050-7
PMCID:
PMC11138567
AbstractArticlePDF–345K
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
Desmoglein 2 Functions As A Receptor for Fatty Acid Binding Protein 4 in Breast Cancer Epithelial Cells
Dongmei Chen, Keith M. Wirth, Scott Kizy, Joseph M. Muretta, Todd W Markowski, Peter Yong, Adam Sheka, Hisham Abdelwahab, Ann V. Hertzel, Sayeed Ikramuddin, Masato Yamamoto, David A Bernlohr
Mol Cancer Res. Author manuscript; available in PMC 2024 Feb 1.
Published in final edited form as: Mol Cancer Res. 2023 Aug 1; 21(8): 836–848. doi: 10.1158/1541-7786.MCR-22-0763
PMCID:
PMC10524127
AbstractArticlePDF–2.1M
5.
Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy by Involving an Integrin-αVβ6/TGF-β Signaling Cascade
Camilla Schinner, Lifen Xu, Henriette Franz, Aude Zimmermann, Marie-Therès Wanuske, Maitreyi Rathod, Pauline Hanns, Florian Geier, Pawel Pelczar, Yan Liang, Vera Lorenz, Chiara Stüdle, Piotr I. Maly, Silke Kauferstein, Britt M. Beckmann, Farah Sheikh, Gabriela M. Kuster, Volker Spindler
Circulation. 2022 Nov 22; 146(21): 1610–1626. Published online 2022 Oct 21. doi: 10.1161/CIRCULATIONAHA.121.057329
PMCID:
PMC9674449
AbstractArticlePDF–5.1M
6.
Desmoglein-2 is important for islet function and β-cell survival
Kay K. Myo Min, Darling Rojas-Canales, Daniella Penko, Mark DeNichilo, Michaelia P. Cockshell, Charlie B. Ffrench, Emma J. Thompson, Olof Asplund, Christopher J. Drogemuller, Rashmi B. Prasad, Leif Groop, Shane T. Grey, Helen E. Thomas, Thomas Loudovaris, Thomas W. Kay, My G. Mahoney, Claire F. Jessup, P. Toby Coates, Claudine S. Bonder
Cell Death Dis. 2022 Oct; 13(10): 911. Published online 2022 Oct 29. doi: 10.1038/s41419-022-05326-2
PMCID:
PMC9617887
AbstractArticlePDF–6.7M
7.
Activation of PPARα Ameliorates Cardiac Fibrosis in Dsg2-Deficient Arrhythmogenic Cardiomyopathy
Zirui Qiu, Yawen Zhao, Tian Tao, Wenying Guo, Ruonan Liu, Jingmin Huang, Geyang Xu
Cells. 2022 Oct; 11(20): 3184. Published online 2022 Oct 11. doi: 10.3390/cells11203184
PMCID:
PMC9601208
AbstractArticlePDF–2.4M
8.
Keratin filaments mediate the expansion of extra‐embryonic membranes in the post‐gastrulation mouse embryo
Wallis Nahaboo, Sema Elif Eski, Evangéline Despin‐Guitard, Marjorie Vermeersch, Marie Versaevel, Bechara Saykali, Daniel Monteyne, Sylvain Gabriele, Thomas M Magin, Nicole Schwarz, Rudolf E Leube, An Zwijsen, David Perez‐Morga, Sumeet Pal Singh, Isabelle Migeotte
EMBO J. 2022 Apr; 41(7): e108747. Published online 2022 Mar 10. doi: 10.15252/embj.2021108747
PMCID:
PMC8982622
AbstractArticlePDF–8.0M
9.
Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy
Stephen P. Chelko, Gizem Keceli, Andrea Carpi, Nunzianna Doti, Jacopo Agrimi, Angeliki Asimaki, Carlos Bueno Beti, Matthew Miyamoto, Nuria Amat-Codina, Djahida Bedja, An-Chi Wei, Brittney Murray, Crystal Tichnell, Chulan Kwon, Hugh Calkins, Cynthia A. James, Brian O’Rourke, Marc K. Halushka, Edon Melloni, Jeffrey E. Saffitz, Daniel P. Judge, Menotti Ruvo, Richard N. Kitsis, Peter Andersen, Fabio Di Lisa, Nazareno Paolocci
Sci Transl Med. Author manuscript; available in PMC 2022 Mar 21.
Published in final edited form as: Sci Transl Med. 2021 Feb 17; 13(581): eabf0891. doi: 10.1126/scitranslmed.abf0891
PMCID:
PMC8936193
AbstractArticlePDF–3.6M
10.
Decrease of Pdzrn3 is required for heart maturation and protects against heart failure
Mathieu Pernot, Béatrice Jaspard-vinassa, Alice Abelanet, Sebastien Rubin, Isabelle Forfar, Sylvie Jeanningros, Laura Cetran, Murielle Han-Yee Yu, Elise Balse, Stéphane Hatem, Pascale Dufourcq, Thierry Couffinhal, Cécile Duplàa
Sci Rep. 2022; 12: 8. Published online 2022 Jan 7. doi: 10.1038/s41598-021-03795-7
PMCID:
PMC8742099
AbstractArticlePDF–3.8M
11.
Desmoglein 2 regulates cardiogenesis by restricting hematopoiesis in the developing murine heart
Hoda Moazzen, Kateryna Venger, Sebastian Kant, Rudolf E. Leube, Claudia A. Krusche
Sci Rep. 2021; 11: 21687. Published online 2021 Nov 4. doi: 10.1038/s41598-021-00996-y
PMCID:
PMC8569146
AbstractArticlePDF–5.2M
12.
A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis
Lisa K. McLellan, Michael R. McAllaster, Arthur S. Kim, Ľubomíra Tóthová, Patrick D. Olson, Jerome S. Pinkner, Allyssa L. Daugherty, Teri N. Hreha, James W. Janetka, Daved H. Fremont, Scott J. Hultgren, Herbert W. Virgin, David A. Hunstad
PLoS Pathog. 2021 Jan; 17(1): e1009314. Published online 2021 Jan 29. doi: 10.1371/journal.ppat.1009314
PMCID:
PMC7875428
AbstractArticlePDF–1.9M
13.
Human Desmoglein-2 and Human CD46 Mediate Human Adenovirus Type 55 Infection, but Human Desmoglein-2 Plays the Major Roles
Ying Feng, Changhua Yi, Xinglong Liu, Linbing Qu, Wan Su, Tao Shu, Xuehua Zheng, Xianmiao Ye, Jia Luo, Mingli Hao, Xikui Sun, Liang Li, Xiaolin Liu, Chenchen Yang, Suhua Guan, Ling Chen, Liqiang Feng
J Virol. 2020 Sep; 94(17): e00747-20. Prepublished online 2020 Jun 24. Published online 2020 Aug 17. doi: 10.1128/JVI.00747-20
PMCID:
PMC7431812
AbstractArticlePDF–3.4M
14.
Inflammation shapes pathogenesis of murine arrhythmogenic cardiomyopathy
Nadine Lubos, Svenja van der Gaag, Muhammed Gerçek, Sebastian Kant, Rudolf E. Leube, Claudia A. Krusche
Basic Res Cardiol. 2020; 115(4): 42. Published online 2020 Jun 12. doi: 10.1007/s00395-020-0803-5
PMCID:
PMC7289786
AbstractArticlePDF–21M
15.
Stabilization of desmoglein-2 binding rescues arrhythmia in arrhythmogenic cardiomyopathy
Camilla Schinner, Bernd Markus Erber, Sunil Yeruva, Angela Schlipp, Vera Rötzer, Ellen Kempf, Sebastian Kant, Rudolf E. Leube, Thomas D. Mueller, Jens Waschke
JCI Insight. 2020 May 7; 5(9): e130141. Published online 2020 May 7. doi: 10.1172/jci.insight.130141
PMCID:
PMC7253015
AbstractArticlePDF–25M
16.
Therapeutic Modulation of the Immune Response in Arrhythmogenic Cardiomyopathy
Stephen P. Chelko, Angeliki Asimaki, Justin Lowenthal, Carlos Bueno-Beti, Djahida Bedja, Arianna Scalco, Nuria Amat-Alarcon, Peter Andersen, Daniel P. Judge, Leslie Tung, Jeffrey E. Saffitz
Circulation. Author manuscript; available in PMC 2020 Oct 29.
Published in final edited form as: Circulation. 2019 Oct 29; 140(18): 1491–1505. Published online 2019 Sep 19. doi: 10.1161/CIRCULATIONAHA.119.040676
PMCID:
PMC6817418
AbstractArticle
17.
Overexpression of Desmoglein 2 in a mouse model of Gorlin syndrome enhances spontaneous basal cell carcinoma formation through STAT3-mediated Gli1 expression
Donna M. Brennan-Crispi, Andrew M. Overmiller, Lukas Tamayo-Orrego, Molly R. Marous, Joya Sahu, Kathleen P. McGuinn, Felicia Cooper, Ioanna Ch. Georgiou, Maxwell Frankfurter, Julio C. Salas-Alanis, Frédéric Charron, Sarah E. Millar, Mỹ G. Mahoney, Natalia A. Riobo-Del Galdo
J Invest Dermatol. Author manuscript; available in PMC 2020 Feb 1.
Published in final edited form as: J Invest Dermatol. 2019 Feb; 139(2): 300–307. Published online 2018 Oct 3. doi: 10.1016/j.jid.2018.09.009
PMCID:
PMC6342634
AbstractArticlePDF–822K
18.
Enhancement of cutaneous wound healing by Dsg2 augmentation of uPAR secretion
Felicia Cooper, Andrew M Overmiller, Anthony Loder, Donna M Brennan-Crispi, Kathleen P McGuinn, Molly R Marous, Theresa A Freeman, Natalia A Riobo-Del Galdo, Linda D Siracusa, James K Wahl, III, Mỹ G Mahoney
J Invest Dermatol. Author manuscript; available in PMC 2019 Nov 1.
Published in final edited form as: J Invest Dermatol. 2018 Nov; 138(11): 2470–2479. Published online 2018 May 9. doi: 10.1016/j.jid.2018.04.024
PMCID:
PMC6200597
AbstractArticlePDF–963K
19.
Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway
Maegen A. Ackermann, Brendan King, Nicole A.P. Lieberman, Prameela J. Bobbili, Michael Rudloff, Christopher E. Berndsen, Nathan T. Wright, Peter A. Hecker, Aikaterini Kontrogianni-Konstantopoulos
J Mol Cell Cardiol. Author manuscript; available in PMC 2017 Nov 19.
Published in final edited form as: J Mol Cell Cardiol. 2017 Oct; 111: 27–39. Published online 2017 Aug 4. doi: 10.1016/j.yjmcc.2017.08.004
PMCID:
PMC5694667
AbstractArticlePDF–3.3M
20.
A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis
Lisa M. Ebert, Lih Y. Tan, M. Zahied Johan, Kay Khine Myo Min, Michaelia P. Cockshell, Kate A. Parham, Kelly L. Betterman, Paceman Szeto, Samantha Boyle, Lokugan Silva, Angela Peng, YouFang Zhang, Andrew Ruszkiewicz, Andrew C. W. Zannettino, Stan Gronthos, Simon Koblar, Natasha L. Harvey, Angel F. Lopez, Mark Shackleton, Claudine S. Bonder
Angiogenesis. 2016; 19(4): 463–486. Published online 2016 Jun 23. doi: 10.1007/s10456-016-9520-y
PMCID:
PMC5026727
AbstractArticlePDF–5.9M

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