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Items: 1 to 20 of 53

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Mechanisms of mGluR‐dependent plasticity in hippocampal area CA2
Mahsa Samadi, Claire A. Hales, Daniel J. Lustberg, Shannon Farris, Madeleine R. Ross, Meilan Zhao, John R. Hepler, Nicholas H. Harbin, Emma S. J. Robinson, Paul J. Banks, Zafar I. Bashir, Serena M. Dudek
Hippocampus. 2023 Jun; 33(6): 730–744. Published online 2023 Mar 27. doi: 10.1002/hipo.23529
PMCID:
PMC10213158
AbstractArticlePDF–3.6M
3.
USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities
Chao Liu, Lingang Sun, Yijun Tan, Qi Wang, Tao Luo, Chenlu Li, Nan Yao, Yuting Xie, Xiao Yi, Yi Zhu, Tiannan Guo, Junfeng Ji
Sci Adv. 2023 May; 9(20): eade3888. Published online 2023 May 17. doi: 10.1126/sciadv.ade3888
PMCID:
PMC10191441
AbstractArticlePDF–2.4M
4.
Tyrosine phosphatase STEP61 in human dementia and in animal models with amyloid and tau pathology
Deonne Taylor, Andrew Kneynsberg, Marloes van Roijen, Jürgen Götz
Mol Brain. 2023; 16: 6. Published online 2023 Jan 13. doi: 10.1186/s13041-023-00994-3
PMCID:
PMC9840288
AbstractArticlePDF–1.0M
5.
Reelin Regulates Neuronal Excitability through Striatal-Enriched Protein Tyrosine Phosphatase (STEP61) and Calcium Permeable AMPARs in an NMDAR-Dependent Manner
Murat S. Durakoglugil, Catherine R. Wasser, Connie H. Wong, Theresa Pohlkamp, Xunde Xian, Courtney Lane-Donovan, Katja Fritschle, Lea Naestle, Joachim Herz
J Neurosci. 2021 Sep 1; 41(35): 7340–7349. doi: 10.1523/JNEUROSCI.0388-21.2021
PMCID:
PMC8412985
AbstractArticlePDF–1.9M
6.
Tyrosine phosphatase STEP is a key regulator of glutamate-induced prostaglandin E2 release from neurons
Sathyanarayanan Rajagopal, Ranjana Poddar, Surojit Paul
J Biol Chem. 2021 Aug; 297(2): 100944. Published online 2021 Jul 8. doi: 10.1016/j.jbc.2021.100944
PMCID:
PMC8326425
AbstractArticlePDF–1.9M
7.
Regulation of post-ischemic inflammatory response: A novel function of the neuronal tyrosine phosphatase STEP
Sathyanarayanan Rajagopal, Changjun Yang, Kelly M. DeMars, Ranjana Poddar, Eduardo Candelario-Jalil, Surojit Paul
Brain Behav Immun. Author manuscript; available in PMC 2022 Mar 1.
Published in final edited form as: Brain Behav Immun. 2021 Mar; 93: 141–155. Published online 2021 Jan 8. doi: 10.1016/j.bbi.2020.12.034
PMCID:
PMC7979508
AbstractArticlePDF–3.4M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription
Jaehong Suh, Donna M. Romano, Larissa Nitschke, Scott P. Herrick, Britt A. DiMarzio, Volodymyr Dzhala, Jun-Seok Bae, Mary K. Oram, Yuejiao Zheng, Basavaraj Hooli, Kristina Mullin, Vincenzo A. Gennarino, Wilma Wasco, Jeremy D. Schmahmann, Mark W. Albers, Huda Y. Zoghbi, Rudolph E. Tanzi
Cell. Author manuscript; available in PMC 2020 Aug 22.
Published in final edited form as: Cell. 2019 Aug 22; 178(5): 1159–1175.e17. doi: 10.1016/j.cell.2019.07.043
PMCID:
PMC6726125
AbstractArticlePDF–3.5M
10.
STEP61: A Member of a Family of Brain-Enriched PTPs Is Localized to the Endoplasmic Reticulum
Abel Bult, Feisha Zhao, Ronald Dirkx Jr., Ela Sharma, Erika Lukacsi, Michele Solimena, Janice R. Naegele, Paul J. Lombroso
J Neurosci. 1996 Dec 15; 16(24): 7821–7831. doi: 10.1523/JNEUROSCI.16-24-07821.1996
PMCID:
PMC6579237
AbstractArticlePDF–1.2M
11.
The STEP61 interactome reveals subunit-specific AMPA receptor binding and synaptic regulation
Sehoon Won, Salvatore Incontro, Yan Li, Roger A. Nicoll, Katherine W. Roche
Proc Natl Acad Sci U S A. 2019 Apr 16; 116(16): 8028–8037. Published online 2019 Apr 1. doi: 10.1073/pnas.1900878116
PMCID:
PMC6475416
AbstractArticlePDF–1.7M
12.
Social Memory and Social Patterns Alterations in the Absence of STriatal-Enriched Protein Tyrosine Phosphatase
Gloria Blázquez, Anna Castañé, Ana Saavedra, Mercè Masana, Jordi Alberch, Esther Pérez-Navarro
Front Behav Neurosci. 2018; 12: 317. Published online 2019 Jan 25. doi: 10.3389/fnbeh.2018.00317
PMCID:
PMC6362413
AbstractArticlePDF–2.6M
13.
Synaptic NMDA receptor activation induces ubiquitination and degradation of STEP61
Jian Xu, Pradeep Kurup, Angus C. Nairn, Paul J. Lombroso
Mol Neurobiol. Author manuscript; available in PMC 2019 Apr 1.
Published in final edited form as: Mol Neurobiol. 2018 Apr; 55(4): 3096–3111. Published online 2017 May 2. doi: 10.1007/s12035-017-0555-x
PMCID:
PMC5668205
AbstractArticlePDF–2.8M
14.
Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models
J Xu, B J Hartley, P Kurup, A Phillips, A Topol, M Xu, C Ononenyi, E Foscue, S-M Ho, T D Baguley, N Carty, C S Barros, U Müller, S Gupta, P Gochman, J Rapoport, J A Ellman, C Pittenger, B Aronow, A C Nairn, M W Nestor, P J Lombroso, K J Brennand
Mol Psychiatry. 2018 Feb; 23(2): 271–281. Published online 2016 Oct 18. doi: 10.1038/mp.2016.163
PMCID:
PMC5395367
AbstractArticlePDF–990K
15.
PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61
Sehoon Won, Salvatore Incontro, Roger A. Nicoll, Katherine W. Roche
Proc Natl Acad Sci U S A. 2016 Aug 9; 113(32): E4736–E4744. Published online 2016 Jul 25. doi: 10.1073/pnas.1609702113
PMCID:
PMC4987792
AbstractArticlePDF–1.5M
16.
STEP signaling pathway mediates psychomotor stimulation and morphine withdrawal symptoms, but not for reward, analgesia and tolerance
Yoon-Jung Kim, Young Kang, Hye-Yeon Park, Jae-Ran Lee, Dae-Yeul Yu, Takuya Murata, Yoichi Gondo, Jung Hwan Hwang, Yong-Hoon Kim, Chul-Ho Lee, Myungchull Rhee, Pyung-Lim Han, Bong-Hyun Chung, Hyun-Jun Lee, Kyoung-Shim Kim
Exp Mol Med. 2016 Feb; 48(2): e212. Published online 2016 Feb 26. doi: 10.1038/emm.2016.1
PMCID:
PMC4892880
AbstractArticlePDF–1.9M
17.
Striatal-enriched protein tyrosine phosphatase modulates nociception: evidence from genetic deletion and pharmacological inhibition
Garikoitz Azkona, Ana Saavedra, Zigor Aira, David Aluja, Xavier Xifró, Tyler Baguley, Jordi Alberch, Jonathan A. Ellman, Paul J. Lombroso, Jon J. Azkue, Esther Pérez-Navarro
Pain. Author manuscript; available in PMC 2017 Feb 1.
Published in final edited form as: Pain. 2016 Feb; 157(2): 377–386. doi: 10.1097/j.pain.0000000000000329
PMCID:
PMC4809206
AbstractArticlePDF–3.2M
18.
Inhibition of the tyrosine phosphatase STEP61 restores BDNF expression and reverses motor and cognitive deficits in phencyclidine-treated mice
Jian Xu, Pradeep Kurup, Tyler D. Baguley, Ethan Foscue, Jonathan A. Ellman, Angus C. Nairn, Paul J. Lombroso
Cell Mol Life Sci. 2016 Apr; 73(7): 1503–1514. Published online 2015 Oct 8. doi: 10.1007/s00018-015-2057-1
PMCID:
PMC4801664
AbstractArticlePDF–1.1M
19.
BDNF Induces Striatal-Enriched Protein Tyrosine Phosphatase 61 Degradation Through the Proteasome
Ana Saavedra, Mar Puigdellívol, Shiraz Tyebji, Pradeep Kurup, Jian Xu, Silvia Ginés, Jordi Alberch, Paul J. Lombroso, Esther Pérez-Navarro
Mol Neurobiol. Author manuscript; available in PMC 2016 Aug 1.
Published in final edited form as: Mol Neurobiol. 2016 Aug; 53(6): 4261–4273. Published online 2015 Jul 30. doi: 10.1007/s12035-015-9335-7
PMCID:
PMC4738169
AbstractArticlePDF–1.3M
20.
Zn2+-dependent Activation of the Trk Signaling Pathway Induces Phosphorylation of the Brain-enriched Tyrosine Phosphatase STEP: MOLECULAR BASIS FOR ZN2+-INDUCED ERK MAPK ACTIVATION
Ranjana Poddar, Sathyanarayanan Rajagopal, C. William Shuttleworth, Surojit Paul
J Biol Chem. 2016 Jan 8; 291(2): 813–825. Published online 2015 Nov 16. doi: 10.1074/jbc.M115.663468
PMCID:
PMC4705400
AbstractArticlePDF–2.0M

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