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Items: 1 to 20 of 377

1.
High-fat-diet-induced hepatic insulin resistance per se attenuates murine de novo lipogenesis
Leigh Goedeke, Jordan W. Strober, Rebecca Suh, Lauren M. Paolella, Xiruo Li, Jillian C. Rogers, Max C. Petersen, Ali R. Nasiri, Gregori Casals, Mario Kahn, Gary W. Cline, Varman T. Samuel, Gerald I. Shulman, Daniel F. Vatner
iScience. 2024 Nov 15; 27(11): 111175. Published online 2024 Oct 15. doi: 10.1016/j.isci.2024.111175
PMCID:
PMC11550620
AbstractArticlePDF–3.7M
2.
Cellular Profile of Subfornical Organ Insulin Receptors in Mice
Han-Rae Kim, Jin-Kwon Jeong, Colin N. Young
Biomolecules. 2024 Oct; 14(10): 1256. Published online 2024 Oct 4. doi: 10.3390/biom14101256
PMCID:
PMC11506324
AbstractArticlePDF–3.5M
3.
Astrocytic GLUT1 reduction paradoxically improves central and peripheral glucose homeostasis
Carlos G. Ardanaz, Aida de la Cruz, Paras S. Minhas, Nira Hernández-Martín, Miguel Ángel Pozo, M. Pilar Valdecantos, Ángela M. Valverde, Palmira Villa-Valverde, Marcos Elizalde-Horcada, Elena Puerta, María J. Ramírez, Jorge E. Ortega, Ainhoa Urbiola, Cristina Ederra, Mikel Ariz, Carlos Ortiz-de-Solórzano, Joaquín Fernández-Irigoyen, Enrique Santamaría, Gerard Karsenty, Jens C. Brüning, Maite Solas
Sci Adv. 2024 Oct 18; 10(42): eadp1115. Published online 2024 Oct 18. doi: 10.1126/sciadv.adp1115
PMCID:
PMC11488540
AbstractArticlePDF–1.7M
4.
Fetuin-B Interacts With Insulin Receptor-β and Promotes Insulin Resistance in Retina Cells
Wenyi Zhang, Xin Wang, Shuwei Tian, Jianming Wang, Aiyi Zhou
Invest Ophthalmol Vis Sci. 2024 Oct; 65(12): 16. Published online 2024 Oct 9. doi: 10.1167/iovs.65.12.16
PMCID:
PMC11469143
AbstractArticlePDF–2.7M
5.
Impact of Serotonin Transporter Absence on Brain Insulin Receptor Expression, Plasma Metabolome Changes, and ADHD-like Behavior in Mice fed a Western Diet
Daniel C. Anthony, Fay Probert, Anna Gorlova, Jenna Hebert, Daniel Radford-Smith, Zlata Nefedova, Aleksei Umriukhin, Andrey Nedorubov, Raymond Cespuglio, Boris Shulgin, Aleksey Lyundup, Klaus Peter Lesch, Tatyana Strekalova
Biomolecules. 2024 Aug; 14(8): 884. Published online 2024 Jul 23. doi: 10.3390/biom14080884
PMCID:
PMC11351952
AbstractArticlePDF–5.4M
6.
Imprinted Grb10, encoding growth factor receptor bound protein 10, regulates fetal growth independently of the insulin-like growth factor type 1 receptor (Igf1r) and insulin receptor (Insr) genes
Kim Moorwood, Florentia M. Smith, Alastair S. Garfield, Andrew Ward
BMC Biol. 2024; 22: 127. Published online 2024 May 30. doi: 10.1186/s12915-024-01926-w
PMCID:
PMC11140863
AbstractArticlePDF–6.8M
7.
Normal Ovarian Function in Subfertile Mouse with Amhr2-Cre-Driven Ablation of Insr and Igf1r
Jenna C. Douglas, Nikola Sekulovski, Madison R. Arreola, Yeongseok Oh, Kanako Hayashi, James A. MacLean, II
Genes (Basel) 2024 May; 15(5): 616. Published online 2024 May 12. doi: 10.3390/genes15050616
PMCID:
PMC11121541
AbstractArticlePDF–7.1M
8.
Hepatitis B virus inhibits insulin receptor signaling and impairs liver regeneration via intracellular retention of the insulin receptor
Sebastian Robert Barthel, Regina Medvedev, Thekla Heinrich, Sarah Manon Büchner, Nadja Kettern, Eberhard Hildt
Cell Mol Life Sci. 2016 Nov; 73(21): 4121–4140. Published online 2016 May 7. doi: 10.1007/s00018-016-2259-1
PMCID:
PMC11108314
AbstractArticlePDF–12M
9.
Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection
Laura Schwartz, Kristin Salamon, Aaron Simoni, Tad Eichler, Ashley R. Jackson, Matthew Murtha, Brian Becknell, Andrew Kauffman, Sarah Linn-Peirano, Natalie Holdsworth, Vidhi Tyagi, Hancong Tang, Steve Rust, Hanna Cortado, Irina Zabbarova, Anthony Kanai, John David Spencer
Cell Rep. Author manuscript; available in PMC 2024 May 15.
Published in final edited form as: Cell Rep. 2024 Apr 23; 43(4): 114007. Published online 2024 Mar 21. doi: 10.1016/j.celrep.2024.114007
PMCID:
PMC11094371
AbstractArticlePDF–2.5M
10.
Insulin and IGF-1 have both overlapping and distinct effects on CD4+ T cell mitochondria, metabolism, and function
Kaitlin Kiernan, Yazan Alwarawrah, Amanda G. Nichols, Keiko Danzaki, Nancie J. MacIver
Sci Rep. 2024; 14: 4331. Published online 2024 Feb 21. doi: 10.1038/s41598-024-54836-w
PMCID:
PMC10881490
AbstractArticlePDF–1.7M
11.
Differential roles of insulin receptor in adipocyte progenitor cells in mice
Yexian Yuan, Zuoxiao Shi, Shaolei Xiong, Ruoci Hu, Qing Song, Zhenyuan Song, Sang-Ging Ong, Yuwei Jiang
Mol Cell Endocrinol. Author manuscript; available in PMC 2024 Feb 6.
Published in final edited form as: Mol Cell Endocrinol. 2023 Aug 1; 573: 111968. Published online 2023 May 25. doi: 10.1016/j.mce.2023.111968
PMCID:
PMC10846871
AbstractArticlePDF–4.1M
12.
Astrocytic insulin receptor controls circadian behavior via dopamine signaling in a sexually dimorphic manner
Antía González-Vila, María Luengo-Mateos, María Silveira-Loureiro, Pablo Garrido-Gil, Nataliia Ohinska, Marco González-Domínguez, Jose Luis Labandeira-García, Cristina García-Cáceres, Miguel López, Olga Barca-Mayo
Nat Commun. 2023; 14: 8175. Published online 2023 Dec 9. doi: 10.1038/s41467-023-44039-8
PMCID:
PMC10710518
AbstractArticlePDF–4.2M
13.
MAD2-Dependent Insulin Receptor Endocytosis Regulates Metabolic Homeostasis
Junhee Park, Catherine Hall, Brandon Hubbard, Traci LaMoia, Rafael Gaspar, Ali Nasiri, Fang Li, Hanrui Zhang, Jiyeon Kim, Rebecca A. Haeusler, Domenico Accili, Gerald I. Shulman, Hongtao Yu, Eunhee Choi
Diabetes. 2023 Dec; 72(12): 1781–1794. Published online 2023 Sep 19. doi: 10.2337/db23-0314
PMCID:
PMC10658066
AbstractArticlePDF–26M
14.
Hippocampus Insulin Receptors Regulate Episodic and Spatial Memory Through Excitatory/Inhibitory Balance
Cai-Yan Xue, Tian Gao, E Mao, Zhen-Zhen Kou, Ling Dong, Feng Gao
ASN Neuro. 2023 Jan-Dec; 15: 17590914231206657. Published online 2023 Oct 31. doi: 10.1177/17590914231206657
PMCID:
PMC10621302
AbstractArticlePDF–4.0M
15.
Genetic activation of glycolysis in osteoblasts preserves bone mass in type I diabetes
Xing Ji, Rebecca Seeley, Ke Li, Fangfang Song, Xueyang Liao, Chao Song, Marco Angelozzi, Arianna Valeri, Tyler Marmo, Wen-Chih Lee, Yu Shi, Fanxin Long
Cell Chem Biol. Author manuscript; available in PMC 2024 Sep 21.
Published in final edited form as: Cell Chem Biol. 2023 Sep 21; 30(9): 1053–1063.e5. Published online 2023 Aug 9. doi: 10.1016/j.chembiol.2023.07.003
PMCID:
PMC10528964
AbstractArticlePDF–2.3M
16.
Activation of brown adipose tissue by a low-protein diet ameliorates hyperglycemia in a diabetic lipodystrophy mouse model
Marcos David Munoz, Alexa Zamudio, Maximilian McCann, Victoria Gil, Pingwen Xu, Chong Wee Liew
Sci Rep. 2023; 13: 11808. Published online 2023 Jul 21. doi: 10.1038/s41598-023-37482-6
PMCID:
PMC10362023
AbstractArticlePDF–5.1M
17.
Ghrelin does not impact the blunted counterregulatory response to recurrent hypoglycemia in mice
Kripa Shankar, Salil Varshney, Deepali Gupta, Bharath K. Mani, Sherri Osborne-Lawrence, Nathan P. Metzger, Corine P. Richard, Jeffrey M. Zigman
Front Endocrinol (Lausanne) 2023; 14: 1181856. Published online 2023 Jun 2. doi: 10.3389/fendo.2023.1181856
PMCID:
PMC10272800
AbstractArticlePDF–2.2M
18.
The insulin receptor regulates the persistence of mechanical nociceptive sensitization in flies and mice
Yan Wang, Roger Lopez-Bellido, Xiaojiao Huo, Annemieke Kavelaars, Michael J. Galko
Biol Open. 2023 Jun 15; 12(6): bio059864. Published online 2023 Jun 1. doi: 10.1242/bio.059864
PMCID:
PMC10245137
AbstractArticlePDF–3.3M
19.
Loss of insulin signaling in astrocytes exacerbates Alzheimer-like phenotypes in a 5xFAD mouse model
Wenqiang Chen, Qian Huang, Ekaterina Katie Lazdon, Antonio Gomes, Marisa Wong, Emily Stephens, Tabitha Grace Royal, Dan Frenkel, Weikang Cai, C. Ronald Kahn
Proc Natl Acad Sci U S A. 2023 May 23; 120(21): e2220684120. Published online 2023 May 15. doi: 10.1073/pnas.2220684120
PMCID:
PMC10214134
AbstractArticlePDF–2.0M
20.
Sex Modulates Response to Renal-Tubule-Targeted Insulin Receptor Deletion in Mice
Soha Sohail, Gabriella Akkawi, Taylor Rechter, Maurice B. Fluitt, Carolyn M. Ecelbarger
Int J Mol Sci. 2023 May; 24(9): 8056. Published online 2023 Apr 29. doi: 10.3390/ijms24098056
PMCID:
PMC10178497
AbstractArticlePDF–3.7M

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