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Items: 1 to 20 of 23

1.
Sexually dimorphic activation of innate antitumor immunity prevents adrenocortical carcinoma development
James J. Wilmouth, Jr., Julie Olabe, Diana Garcia-Garcia, Cécily Lucas, Rachel Guiton, Florence Roucher-Boulez, Damien Dufour, Christelle Damon-Soubeyrand, Isabelle Sahut-Barnola, Jean-Christophe Pointud, Yoan Renaud, Adrien Levasseur, Igor Tauveron, Anne-Marie Lefrançois-Martinez, Antoine Martinez, Pierre Val
Sci Adv. 2022 Oct; 8(41): eadd0422. Published online 2022 Oct 14. doi: 10.1126/sciadv.add0422
PMCID:
PMC9565812
AbstractArticlePDF–4.8M
2.
RNF43/ZNRF3 negatively regulates taste tissue homeostasis and positively regulates dorsal lingual epithelial tissue homeostasis
Chanyi Lu, Xiaoli Lin, Jumpei Yamashita, Ranhui Xi, Minliang Zhou, Yali V. Zhang, Hong Wang, Robert F. Margolskee, Bon-Kyoung Koo, Hans Clevers, Ichiro Matsumoto, Peihua Jiang
Stem Cell Reports. 2022 Feb 8; 17(2): 369–383. Published online 2022 Jan 6. doi: 10.1016/j.stemcr.2021.12.002
PMCID:
PMC8828551
AbstractArticlePDF–5.5M
3.
Arrest of WNT/β-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries
Morgane Le Rolle, Filippo Massa, Pam Siggers, Laurent Turchi, Agnès Loubat, Bon-Kyoung Koo, Hans Clevers, Andy Greenfield, Andreas Schedl, Marie-Christine Chaboissier, Anne-Amandine Chassot
Proc Natl Acad Sci U S A. 2021 Jul 27; 118(30): e2023376118. Published online 2021 Jul 23. doi: 10.1073/pnas.2023376118
PMCID:
PMC8325354
AbstractArticlePDF–4.3M
4.
Apc-mutant cells deploy Notum to bias clonal competition and drive cancer
Dustin J. Flanagan, Nalle Pentinmikko, Kalle Luopajärvi, Nicky J. Willis, Kathryn Gilroy, Alexander P. Raven, Lynn Mcgarry, Johanna I. Englund, Anna Webb, Sandra Scharaw, Nadia Nasreddin, Michael C. Hodder, Rachel A. Ridgway, Emma Minnee, Nathalie Sphyris, Ella Gilchrist, Arafath K. Najumudeen, Beatrice Romagnolo, Christine Perret, Ann C. Williams, Hans Clevers, Pirjo Nummela, Marianne Lähde, Kari Alitalo, Ville Hietakangas, Ann Hedley, William Clark, Colin Nixon, Kristina Kirschner, E. Yvonne Jones, Ari Ristimäki, Simon Leedham, Paul V. Fish, Jean-Paul Vincent, Pekka Katajisto, Owen J. Sansom
Nature. Author manuscript; available in PMC 2023 Sep 7.
Published in final edited form as: Nature. 2021 Jun 1; 594(7863): 430–435. Published online 2021 Jun 2. doi: 10.1038/s41586-021-03525-z
PMCID:
PMC7615049
AbstractArticlePDF–3.9M
5.
LGR5 controls extracellular matrix production by stem cells in the developing intestine
Valeria Fernandez Vallone, Morgane Leprovots, Didac Ribatallada‐Soriano, Romain Gerbier, Anne Lefort, Frédérick Libert, Gilbert Vassart, Marie‐Isabelle Garcia
EMBO Rep. 2020 Jul 3; 21(7): e49224. Published online 2020 May 28. doi: 10.15252/embr.201949224
PMCID:
PMC7332981
AbstractArticlePDF–7.1M
6.
R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors
Valerie PI Vidal, Fariba Jian-Motamedi, Samah Rekima, Elodie P Gregoire, Emmanuelle Szenker-Ravi, Marc Leushacke, Bruno Reversade, Marie-Christine Chaboissier, Andreas Schedl
eLife. 2020; 9: e53895. Published online 2020 May 1. doi: 10.7554/eLife.53895
PMCID:
PMC7228766
AbstractArticlePDF–10M
7.
LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling
Jin Huk Choi, Xue Zhong, William McAlpine, Tzu-Chieh Liao, Duanwu Zhang, Beibei Fang, Jamie Russell, Sara Ludwig, Evan Nair-Gill, Zhao Zhang, Kuan-wen Wang, Takuma Misawa, Xiaoming Zhan, Mihwa Choi, Tao Wang, Xiaohong Li, Miao Tang, Qihua Sun, Liyang Yu, Anne R. Murray, Eva Marie Y. Moresco, Bruce Beutler
Science. Author manuscript; available in PMC 2020 May 8.
Published in final edited form as: Science. 2019 May 10; 364(6440): eaau0812. doi: 10.1126/science.aau0812
PMCID:
PMC7206793
AbstractArticlePDF–2.2M
8.
An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance
Ningning Li, Roya Babaei-Jadidi, Federica Lorenzi, Bradley Spencer-Dene, Philip Clarke, Enric Domingo, Eugene Tulchinsky, Robert G. J. Vries, David Kerr, Yihang Pan, Yulong He, David O. Bates, Ian Tomlinson, Hans Clevers, Abdolrahman S. Nateri
Oncogenesis. 2019 Mar; 8(3): 13. Published online 2019 Feb 19. doi: 10.1038/s41389-019-0125-3
PMCID:
PMC6381143
AbstractArticlePDF–10M
9.
A ZNRF3-dependent Wnt/β-catenin signaling gradient is required for adrenal homeostasis
Kaitlin J. Basham, Stéphanie Rodriguez, Adina F. Turcu, Antonio M. Lerario, Catriona Y. Logan, Madeline R. Rysztak, Celso E. Gomez-Sanchez, David T. Breault, Bon-Kyoung Koo, Hans Clevers, Roeland Nusse, Pierre Val, Gary D. Hammer
Genes Dev. 2019 Feb 1; 33(3-4): 209–220. doi: 10.1101/gad.317412.118
PMCID:
PMC6362817
AbstractArticlePDF–10M
10.
ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling
Abigail Harris, Pam Siggers, Silvia Corrochano, Nick Warr, Danielle Sagar, Daniel T. Grimes, Makoto Suzuki, Rebecca D. Burdine, Feng Cong, Bon-Kyoung Koo, Hans Clevers, Isabelle Stévant, Serge Nef, Sara Wells, Raja Brauner, Bochra Ben Rhouma, Neïla Belguith, Caroline Eozenou, Joelle Bignon-Topalovic, Anu Bashamboo, Ken McElreavey, Andy Greenfield
Proc Natl Acad Sci U S A. 2018 May 22; 115(21): 5474–5479. Published online 2018 May 7. doi: 10.1073/pnas.1801223115
PMCID:
PMC6003506
AbstractArticlePDF–1.0M
11.
Crystal structure of R-spondin 2 in complex with the ectodomains of its receptors LGR5 and ZNRF3
Matthias Zebisch, E. Yvonne Jones
J Struct Biol. 2015 Aug; 191(2): 149–155. doi: 10.1016/j.jsb.2015.05.008
PMCID:
PMC4533229
AbstractArticlePDF–2.4M
12.
Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia
Bon-Kyoung Koo, Johan H. van Es, Maaike van den Born, Hans Clevers
Proc Natl Acad Sci U S A. 2015 Jun 16; 112(24): 7548–7550. Published online 2015 May 28. doi: 10.1073/pnas.1508113112
PMCID:
PMC4475934
AbstractArticlePDF–1.0M
13.
Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin
Matthias Zebisch, Yang Xu, Christos Krastev, Bryan T. MacDonald, Maorong Chen, Robert J. C. Gilbert, Xi He, E. Yvonne Jones
Nat Commun. 2013 Nov 14; 4: 2787. Published online 2013 Nov 14. doi: 10.1038/ncomms3787
PMCID:
PMC3905715
AbstractArticlePDF–2.4M
14.
Structures of Wnt-Antagonist ZNRF3 and Its Complex with R-Spondin 1 and Implications for Signaling
Weng Chuan Peng, Wim de Lau, Pramod K. Madoori, Federico Forneris, Joke C. M. Granneman, Hans Clevers, Piet Gros
PLoS One. 2013; 8(12): e83110. Published online 2013 Dec 12. doi: 10.1371/journal.pone.0083110
PMCID:
PMC3861454
AbstractArticlePDF–1.6M
15.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
18.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M
19.
Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes
Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki
Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100
PMCID:
PMC310980
AbstractArticlePDF–1.4M
20.
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands
Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100
Correction in:
Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.
PMCID:
PMC283554
AbstractArticlePDF–481K

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