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Select item 112017421.

CD3ζ-Mediated Signaling Protects Retinal Ganglion Cells in Glutamate Excitotoxicity of the Retina

Rui Du, Ping Wang, Ning Tian

Cells. 2024 Jun; 13(12): 1006. Published online 2024 Jun 8. doi: 10.3390/cells13121006

PMCID:: PMC11201742

Abstract Article PDF–25M

Select item 92957702.

A set point in the selection of the αβTCR T cell repertoire imposed by pre-TCR signaling strength

Elena R. Bovolenta, Eva M. García-Cuesta, Lydia Horndler, Julia Ponomarenko, Wolfgang W. Schamel, Mario Mellado, Mario Castro, David Abia, Hisse M. van Santen

Proc Natl Acad Sci U S A. 2022 May 31; 119(22): e2201907119. Published online 2022 May 26. doi: 10.1073/pnas.2201907119

PMCID:: PMC9295770

Abstract Article PDF–1.6M

Select item 89954713.

Reduction of Cell Surface T-Cell Receptor by Non-Mitogenic CD3 Antibody to Mitigate Murine Lupus

Masashi Morita, Masayuki Mizui, Satoshi Masuyama, George C. Tsokos, Yoshitaka Isaka

Front Immunol. 2022; 13: 855812. Published online 2022 Mar 28. doi: 10.3389/fimmu.2022.855812

PMCID:: PMC8995471

Abstract Article PDF–4.6M

Select item 89530854.

The CD3ζ adaptor structure determines functional differences between human and mouse CD16 Fc receptor signaling

Oscar A. Aguilar, Lam-Kiu Fong, Kenichi Ishiyama, William F. DeGrado, Lewis L. Lanier

J Exp Med. 2022 May 2; 219(5): e20220022. Published online 2022 Mar 23. doi: 10.1084/jem.20220022

PMCID:: PMC8953085

Abstract Article PDF–6.1M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 66188076.

Impaired Spatial Memory in Mice Lacking CD3ζ Is Associated with Altered NMDA and AMPA Receptors Signaling Independent of T-Cell Deficiency

Antoine Louveau, Julie Angibaud, Fabienne Haspot, Maria Cecilia Opazo, Reynald Thinard, Virginie Thepenier, Stéphane J. Baudouin, Laurent Lescaudron, Philippe Hulin, Claudia A. Riedel, Hélène Boudin

J Neurosci. 2013 Nov 20; 33(47): 18672–18685. doi: 10.1523/JNEUROSCI.3028-13.2013

PMCID:: PMC6618807

Abstract Article PDF–2.8M

Select item 62490577.

Interleukin-17 producing γδ T cells originate from SOX13⁺ progenitors that are independent of γδTCR signaling

Nicholas A Spidale, Katelyn Sylvia, Kavitha Narayan, Bing Miu, Michela Frascoli, Heather J Melichar, Wu Zhihao, Jan Kisielow, Amy Palin, Thomas Serwold, Paul Love, Michihiro Kobayashi, Momoko Yoshimoto, Nitya Jain, Joonsoo Kang

Immunity. Author manuscript; available in PMC 2019 Nov 20.

Published in final edited form as: Immunity. 2018 Nov 20; 49(5): 857–872.e5. Published online 2018 Nov 6. doi: 10.1016/j.immuni.2018.09.010

PMCID:: PMC6249057

Abstract Article PDF–1.5M

Select item 62197348.

SOX4 controls invariant NKT cell differentiation by tuning TCR signaling

Nidhi Malhotra, Yilin Qi, Nicholas A. Spidale, Michela Frascoli, Bing Miu, Okhyun Cho, Katelyn Sylvia, Joonsoo Kang

J Exp Med. 2018 Nov 5; 215(11): 2887–2900. doi: 10.1084/jem.20172021

PMCID:: PMC6219734

Abstract Article PDF–2.7M

Select item 61908999.

Interferon-α Up-Regulates the Expression of PD-L1 Molecules on Immune Cells Through STAT3 and p38 Signaling

Alexandr V. Bazhin, Katharina von Ahn, Jasmin Fritz, Jens Werner, Svetlana Karakhanova

Front Immunol. 2018; 9: 2129. Published online 2018 Sep 27. doi: 10.3389/fimmu.2018.02129

PMCID:: PMC6190899

Abstract Article PDF–1.8M

Select item 616686310.

NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development

Vedrana Jelenčić, Marko Šestan, Inga Kavazović, Maja Lenartić, Sonja Marinović, Tim D. Holmes, Michaela Prchal-Murphy, Berislav Lisnić, Veronika Sexl, Yenan T. Bryceson, Felix M. Wensveen, Bojan Polić

Nat Immunol. Author manuscript; available in PMC 2019 Mar 17.

Published in final edited form as: Nat Immunol. 2018 Oct; 19(10): 1083–1092. Published online 2018 Sep 17. doi: 10.1038/s41590-018-0209-9

PMCID:: PMC6166863

Abstract Article PDF–1.6M

Select item 604844311.

Downregulation of CD3ζ in Natural Killer Cells from Systemic Lupus Erythematosus Patients Confers a Pro-Inflammatory Phenotype

Abel Suárez-Fueyo, Sean J. Bradley, Takayuki Katsuyama, Sarah Solomon, Eri Katsuyama, Vasileios C. Kyttaris, Vaishali R. Moulton, George C. Tsokos

J Immunol. Author manuscript; available in PMC 2019 May 1.

Published in final edited form as: J Immunol. 2018 May 1; 200(9): 3077–3086. Published online 2018 Mar 30. doi: 10.4049/jimmunol.1700588

PMCID:: PMC6048443

Abstract Article PDF–935K

Select item 556847512.

CD3 ITAM diversity is required for optimal T cell receptor signaling and thymocyte development

Matthew L. Bettini, Po-Chein Chou, Clifford Guy, Thomas Lee, Kate M. Vignali, Dario A.A. Vignali

J Immunol. Author manuscript; available in PMC 2018 Sep 1.

Published in final edited form as: J Immunol. 2017 Sep 1; 199(5): 1555–1560. Published online 2017 Jul 21. doi: 10.4049/jimmunol.1700069

PMCID:: PMC5568475

Abstract Article PDF–674K

Select item 540486813.

The effects of immune protein CD3ζ development and degeneration of retinal neurons after optic nerve injury

Tao He, Xavier Mortensen, Ping Wang, Ning Tian

PLoS One. 2017; 12(4): e0175522. Published online 2017 Apr 25. doi: 10.1371/journal.pone.0175522

Correction in:: PLoS One. 2018; 13(6): e0198770.

PMCID:: PMC5404868

Abstract Article PDF–7.5M

Select item 465965914.

Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice

Thais A. Fornari, Paula B. Donate, Amanda F. Assis, Claudia Macedo, Elza T. Sakamoto-Hojo, Eduardo A. Donadi, Geraldo A. Passos

PLoS One. 2015; 10(11): e0142688. Published online 2015 Nov 25. doi: 10.1371/journal.pone.0142688

PMCID:: PMC4659659

Abstract Article PDF–2.9M

Select item 424823915.

Ligand engaged TCR is triggered by Lck not associated with CD8 coreceptor

Javier Casas, Joanna Brzostek, Veronika I. Zarnitsyna, Jin-sung Hong, Qianru Wei, John A.H. Hoerter, Guo Fu, Jeanette Ampudia, Rose Zamoyska, Cheng Zhu, Nicholas R.J. Gascoigne

Nat Commun. Author manuscript; available in PMC 2015 May 27.

Published in final edited form as: Nat Commun. 2014; 5: 5624. Published online 2014 Nov 27. doi: 10.1038/ncomms6624

PMCID:: PMC4248239

Abstract Article PDF–2.1M

Select item 407029116.

T Cell CD3ζ Deficiency Enables Multiorgan Tissue Inflammation

Guo-Min Deng, Jessica Beltran, Chen Chen, Cox Terhorst, George C. Tsokos

J Immunol. Author manuscript; available in PMC 2014 Jun 25.

Published in final edited form as: J Immunol. 2013 Oct 1; 191(7): 3563–3567. Published online 2013 Aug 26. doi: 10.4049/jimmunol.1300634

PMCID:: PMC4070291

Abstract Article PDF–772K

Select item 406580317.

Membrane association of the CD3ε signaling domain is required for optimal T cell development and function

Matthew L. Bettini, Clifford Guy, Pradyot Dash, Kate M. Vignali, David E. Hamm, Jessica Dobbins, Etienne Gagnon, Paul G. Thomas, Kai W. Wucherpfennig, Dario A.A. Vignali

J Immunol. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: J Immunol. 2014 Jul 1; 193(1): 258–267. Published online 2014 Jun 4. doi: 10.4049/jimmunol.1400322

PMCID:: PMC4065803

Abstract Article PDF–1.4M

Select item 403756018.

Quantitative proteomic analysis of signalosome dynamics in primary T cells identifies the CD6 surface receptor as a Lat-independent TCR signaling hub

Romain Roncagalli, Simon Hauri, Fréderic Fiore, Yinming Liang, Zhi Chen, Amandine Sansoni, Kartiek Kanduri, Rachel Joly, Aurélie Malzac, Harri Lähdesmäki, Riitta Lahesmaa, Sho Yamasaki, Takashi Saito, Marie Malissen, Ruedi Aebersold, Matthias Gstaiger, Bernard Malissen

Nat Immunol. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Nat Immunol. 2014 Apr; 15(4): 384–392. Published online 2014 Mar 2. doi: 10.1038/ni.2843

PMCID:: PMC4037560

Abstract Article PDF–3.1M

Select item 396496419.

The Vertebrate Genome Annotation browser 10 years on

Jennifer L. Harrow, Charles A. Steward, Adam Frankish, James G. Gilbert, Jose M. Gonzalez, Jane E. Loveland, Jonathan Mudge, Dan Sheppard, Mark Thomas, Stephen Trevanion, Laurens G. Wilming

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D771–D779. Published online 2013 Dec 6. doi: 10.1093/nar/gkt1241

PMCID:: PMC3964964

Abstract Article PDF–11M

Select item 379265020.

Lck availability during thymic selection determines the recognition specificity of the T cell repertoire

François Van Laethem, Anastasia N. Tikhonova, Leonid A. Pobezinsky, Xuguang Tai, Motoko Y. Kimura, Cecile Le Saout, Terry I. Guinter, Anthony Adams, Susan O. Sharrow, Günter Bernhardt, Lionel Feigenbaum, Alfred Singer

Cell. Author manuscript; available in PMC 2014 Sep 12.

Published in final edited form as: Cell. 2013 Sep 12; 154(6): 1326–1341. doi: 10.1016/j.cell.2013.08.009

PMCID:: PMC3792650

Abstract Article PDF–3.8M

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