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Items: 1 to 20 of 314

1.
Early-stage lung cancer is driven by a transitional cell state dependent on a KRAS-ITGA3-SRC axis
Aaron L Moye, Antonella FM Dost, Robert Ietswaart, Shreoshi Sengupta, VanNashlee Ya, Chrystal Aluya, Caroline G Fahey, Sharon M Louie, Margherita Paschini, Carla F Kim
EMBO J. 2024 Jul; 43(14): 2843–2861. Published online 2024 May 16. doi: 10.1038/s44318-024-00113-5
PMCID:
PMC11251082
AbstractArticlePDF–4.3M
2.
Interaction of galectin-1 with caveolae induces mouse embryonic stem cell proliferation through the Src, ERas, Akt and mTOR signaling pathways
M. Y. Lee, S. H. Lee, J. H. Park, H. J. Han
Cell Mol Life Sci. 2009 Apr; 66(8): 1467–1478. Published online 2009 Mar 9. doi: 10.1007/s00018-009-8691-8
PMCID:
PMC11131554
AbstractArticlePDF–2.6M
3.
Metastasis suppressor 1 controls osteoblast differentiation and bone homeostasis through regulating Src-Wnt/β-catenin signaling
Meng Chen, Liying Shan, Ying Gan, Lijie Tian, Jie Zhou, Endong Zhu, Hairui Yuan, Xiaoxia Li, Baoli Wang
Cell Mol Life Sci. 2022 Feb; 79(2): 107. Published online 2022 Jan 30. doi: 10.1007/s00018-022-04147-y
PMCID:
PMC11072310
AbstractArticlePDF–6.6M
4.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
5.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
6.
SRC and TKS5 mediated podosome formation in fibroblasts promotes extracellular matrix invasion and pulmonary fibrosis
Ilianna Barbayianni, Paraskevi Kanellopoulou, Dionysios Fanidis, Dimitris Nastos, Eleftheria-Dimitra Ntouskou, Apostolos Galaris, Vaggelis Harokopos, Pantelis Hatzis, Eliza Tsitoura, Robert Homer, Naftali Kaminski, Katerina M. Antoniou, Bruno Crestani, Argyrios Tzouvelekis, Vassilis Aidinis
Nat Commun. 2023; 14: 5882. Published online 2023 Sep 21. doi: 10.1038/s41467-023-41614-x
PMCID:
PMC10514346
AbstractArticlePDF–5.6M
7.
Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development
Jiyoung Lee, Yeonjoo Kim, Paris Ataliotis, Hyung-Goo Kim, Dae-Won Kim, Dorothy C. Bennett, Nigel A. Brown, Lawrence C. Layman, Soo-Hyun Kim
Sci Rep. 2023; 13: 12309. Published online 2023 Jul 29. doi: 10.1038/s41598-023-38017-9
PMCID:
PMC10387110
AbstractArticlePDF–11M
8.
DTX3L Enhances Type I Interferon Antiviral Response by Promoting the Ubiquitination and Phosphorylation of TBK1
Jiaqi Huang, Zhengrong Chen, Yunfei Ye, Yu Shao, Peijie Zhu, Xiaoping Li, Yu Ma, Fei Xu, Ji Zhou, Mengyun Wu, Xiu Gao, Yi Yang, Jinping Zhang, Chuangli Hao
J Virol. 2023 Jun; 97(6): e00687-23. Published online 2023 May 31. doi: 10.1128/jvi.00687-23
PMCID:
PMC10308958
AbstractArticlePDF–4.8M
9.
Corneal Edema in Inducible Slc4a11 Knockout Is Initiated by Mitochondrial Superoxide Induced Src Kinase Activation
Diego G. Ogando, Edward T. Kim, Shimin Li, Joseph A. Bonanno
Cells. 2023 Jun; 12(11): 1528. Published online 2023 Jun 1. doi: 10.3390/cells12111528
PMCID:
PMC10253072
AbstractArticlePDF–13M
10.
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome
Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh
Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5
PMCID:
PMC10208958
AbstractArticlePDF–7.0M
11.
Trogocytosis Results in Sustained Intracellular Signaling in CD4+ T Cells
Douglas G. Osborne, Scott A. Wetzel
J Immunol. Author manuscript; available in PMC 2022 Nov 3.
Published in final edited form as: J Immunol. 2012 Nov 15; 189(10): 4728–4739. Published online 2012 Oct 12. doi: 10.4049/jimmunol.1201507
PMCID:
PMC9631952
AbstractArticlePDF–1.8M
12.
Targeted Disruption of Leucine-Rich Repeat Kinase 1 But Not Leucine-Rich Repeat Kinase 2 in Mice Causes Severe Osteopetrosis
Weirong Xing, Jeff Liu, Shaohong Cheng, Peter Vogel, Subburaman Mohan, Robert Brommage
J Bone Miner Res. Author manuscript; available in PMC 2022 Oct 3.
Published in final edited form as: J Bone Miner Res. 2013 Sep; 28(9): 1962–1974. doi: 10.1002/jbmr.1935
PMCID:
PMC9528686
AbstractArticlePDF–2.7M
13.
TWIST1 interacts with β/δ-catenins during neural tube development and regulates fate transition in cranial neural crest cells
Jessica W. Bertol, Shelby Johnston, Rabia Ahmed, Victoria K. Xie, Kelsea M. Hubka, Lissette Cruz, Larissa Nitschke, Marta Stetsiv, Jeremy P. Goering, Paul Nistor, Sally Lowell, Hanne Hoskens, Peter Claes, Seth M. Weinberg, Irfan Saadi, Mary C. Farach-Carson, Walid D. Fakhouri
Development. 2022 Aug 1; 149(15): dev200068. Published online 2022 Aug 8. doi: 10.1242/dev.200068
PMCID:
PMC9440756
AbstractArticle
14.
Src-homology domain 2 containing protein tyrosine phosphatase-1 (SHP-1) directly binds to proto-oncogene tyrosine-protein kinase Src (c-Src) and promotes the transcriptional activation of connexin 43 (Cx43)
YiHao Liu, Meng Dai, PengHui Yang, Li Cao, Li Lu
Bioengineered. 2022; 13(5): 13534–13543. Published online 2022 Jun 5. doi: 10.1080/21655979.2022.2079252
PMCID:
PMC9276044
AbstractArticlePDF–5.3M
15.
A molecular subtype of colorectal cancers initiates independently of epidermal growth factor receptor and has an accelerated growth rate mediated by IL10-dependent anergy
Carolina Mantilla-Rojas, Ming Yu, Erica S. Rinella, Rachel M. Lynch, Amie Perry, Jorge Jaimes-Alvarado, Kathryn R. Anderson, Estefania Barba, Evann J. Bourgeois, Kranti Konganti, David W. Threadgill
Oncogene. Author manuscript; available in PMC 2022 May 17.
Published in final edited form as: Oncogene. 2021 Apr; 40(17): 3047–3059. Published online 2021 Mar 25. doi: 10.1038/s41388-021-01752-2
PMCID:
PMC9113393
AbstractArticlePDF–1.5M
16.
Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling
In-Chi Young, Bogang Wu, Jaclyn Andricovich, Sung-Ting Chuang, Rong Li, Alexandros Tzatsos, Ray-Chang Wu, Mei-Yi Wu
Cell Rep. Author manuscript; available in PMC 2022 Jan 3.
Published in final edited form as: Cell Rep. 2021 Nov 23; 37(8): 110036. doi: 10.1016/j.celrep.2021.110036
PMCID:
PMC8722094
AbstractArticlePDF–1.7M
17.
Redox-dependent activation of Src kinase mediates epithelial IL-33 production and signaling during acute airway allergen challenge
Christopher M. Dustin, Aida Habibovic, Milena Hristova, Caspar Schiffers, Carolyn R. Morris, Miao-Chong Joy Lin, Robert A. Bauer, David E. Heppner, Nirav Daphtary, Minara Aliyeva, Albert van der Vliet
J Immunol. Author manuscript; available in PMC 2022 Jun 15.
Published in final edited form as: J Immunol. 2021 Jun 15; 206(12): 2989–2999. Published online 2021 Jun 4. doi: 10.4049/jimmunol.2000995
PMCID:
PMC8642476
AbstractArticlePDF–2.0M
18.
TRPA1-Mediated Src Family Kinases Activity Facilitates Cortical Spreading Depression Susceptibility and Trigeminovascular System Sensitization
Lingdi Nie, Liwen Jiang, John P. Quinn, Blair D. Grubb, Minyan Wang
Int J Mol Sci. 2021 Nov; 22(22): 12273. Published online 2021 Nov 12. doi: 10.3390/ijms222212273
PMCID:
PMC8620265
AbstractArticlePDF–25M
19.
The Na/K-ATPase α1/Src interaction regulates metabolic reserve and Western diet intolerance
Laura C Kutz, Xiaoyu Cui, Jeffrey X. Xie, Shreya T Mukherji, Kayleigh C Terrell, Minqi Huang, Xiaoliang Wang, Jiayan Wang, Adam J Martin, Marco T Pessoa, Liquan Cai, Hua Zhu, Judith A Heiny, Joseph I Shapiro, Gustavo Blanco, Zijian Xie, Sandrine V Pierre
Acta Physiol (Oxf) Author manuscript; available in PMC 2022 Jul 1.
Published in final edited form as: Acta Physiol (Oxf). 2021 Jul; 232(3): e13652. Published online 2021 Apr 4. doi: 10.1111/apha.13652
PMCID:
PMC8570534
AbstractArticlePDF–3.0M
20.
Mesenchymal stem cell-derived small extracellular vesicles mitigate oxidative stress-induced senescence in endothelial cells via regulation of miR-146a/Src
Xian Xiao, Meiqian Xu, Hongliang Yu, Liping Wang, Xiaoxia Li, Janusz Rak, Shihua Wang, Robert Chunhua Zhao
Signal Transduct Target Ther. 2021; 6: 354. Published online 2021 Oct 22. doi: 10.1038/s41392-021-00765-3
Correction in:
Signal Transduct Target Ther. 2022; 7: 234.
PMCID:
PMC8531331
AbstractArticlePDF–8.4M

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