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Select item 106573471.

ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury

Yankun Zhang, Yuchen Fan, Huili Hu, Xiaohui Zhang, Zehua Wang, Zhuanchang Wu, Liyuan Wang, Xiangguo Yu, Xiaojia Song, Peng Xiang, Xiaodong Zhang, Tixiao Wang, Siyu Tan, Chunyang Li, Lifen Gao, Xiaohong Liang, Shuijie Li, Nailin Li, Xuetian Yue, Chunhong Ma

Nat Commun. 2023; 14: 7527. Published online 2023 Nov 18. doi: 10.1038/s41467-023-43439-0

PMCID:: PMC10657347

Abstract Article PDF–7.6M

Select item 97014862.

Zinc fingers and homeoboxes 2 is required for diethylnitrosamine‐induced liver tumor formation in C57BL/6 mice

Jieyun Jiang, Courtney Turpin, Guofang (Shirley) Qiu, Mei Xu, Eun Lee, Terry D. Hinds, Jr., Martha L. Peterson, Brett T. Spear

Hepatol Commun. 2022 Dec; 6(12): 3550–3562. Published online 2022 Oct 4. doi: 10.1002/hep4.2106

PMCID:: PMC9701486

Abstract Article PDF–16M

Select item 94675843.

Novel regulation of the transcription factor ZHX2 by N-terminal methylation

Meghan M. Conner, Haley V. Parker, Daniela R. Falcone, Gehoon Chung, Christine E. Schaner Tooley

Transcription. 2022; 13(1-3): 1–15. Published online 2022 May 25. doi: 10.1080/21541264.2022.2079184

PMCID:: PMC9467584

Abstract Article PDF–2.3M

Select item 93412494.

Zhx2 Is a Candidate Gene Underlying Oxymorphone Metabolite Brain Concentration Associated with State-Dependent Oxycodone Reward

Jacob A. Beierle, Emily J. Yao, Stanley I. Goldstein, William B. Lynch, Julia L. Scotellaro, Anyaa A. Shah, Katherine D. Sena, Alyssa L. Wong, Colton L. Linnertz, Olga Averin, David E. Moody, Christopher A. Reilly, Gary Peltz, Andrew Emili, Martin T. Ferris, Camron D. Bryant

J Pharmacol Exp Ther. 2022 Aug; 382(2): 167–180. Published online 2022 Aug. doi: 10.1124/jpet.122.001217

PMCID:: PMC9341249

Abstract Article PDF–2.2M

Select item 83132395.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 82921326.

Transcription factor Zhx2 restricts NK cell maturation and suppresses their antitumor immunity

Siyu Tan, Xiaowei Guo, Mengzhen Li, Tixiao Wang, Zehua Wang, Chunyang Li, Zhuanchang Wu, Nailin Li, Lifen Gao, Xiaohong Liang, Chunhong Ma

J Exp Med. 2021 Sep 6; 218(9): e20210009. Published online 2021 Jul 19. doi: 10.1084/jem.20210009

PMCID:: PMC8292132

Abstract Article PDF–7.0M

Select item 80721327.

Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex

Pauline Antonie Ulmke, M. Sadman Sakib, Peter Ditte, Godwin Sokpor, Cemil Kerimoglu, Linh Pham, Yuanbin Xie, Xiaoyi Mao, Joachim Rosenbusch, Ulrike Teichmann, Huu Phuc Nguyen, Andre Fischer, Gregor Eichele, Jochen F. Staiger, Tran Tuoc

Stem Cell Reports. 2021 Apr 13; 16(4): 968–984. Published online 2021 Apr 1. doi: 10.1016/j.stemcr.2021.03.008

PMCID:: PMC8072132

Abstract Article PDF–8.1M

Select item 73943658.

The zinc fingers and homeoboxes 2 protein ZHX2 and its interacting proteins regulate upstream pathways in podocyte diseases

Camille Macé, Maria Del Nogal Avila, Caroline B. Marshall, Joubert Kharlyngdoh, Ranjan Das, Eduardo Molina-Jijon, Hector Donoro Blazquez, Suresh Shastry, Elisabeth Soria, Jack Wetzels, Henry Dijkman, Carmen Avila-Casado, Lionel C. Clement, Sumant S. Chugh

Kidney Int. Author manuscript; available in PMC 2021 Apr 1.

Published in final edited form as: Kidney Int. 2020 Apr; 97(4): 753–764. Published online 2019 Nov 26. doi: 10.1016/j.kint.2019.11.011

PMCID:: PMC7394365

Abstract Article PDF–2.3M

Select item 72060729.

Tumor suppressor ZHX2 inhibits NAFLD–HCC progression via blocking LPL-mediated lipid uptake

Zhuanchang Wu, Hongxin Ma, Liyuan Wang, Xiaojia Song, Jie Zhang, Wen Liu, Yutong Ge, Yang Sun, Xiangguo Yu, Zehua Wang, Jianping Wang, Yankun Zhang, Chunyang Li, Nailin Li, Lifen Gao, Xiaohong Liang, Xuetian Yue, Chunhong Ma

Cell Death Differ. 2020 May; 27(5): 1693–1708. Published online 2019 Nov 18. doi: 10.1038/s41418-019-0453-z

PMCID:: PMC7206072

Abstract Article PDF–6.2M

Select item 676102310.

Liver size and lipid content differences between BALB/c and BALB/cJ mice on a high fat diet are due, in part, to Zhx2

Erica L. Clinkenbeard, Courtney Turpin, Jieyun Jiang, Martha L. Peterson, Brett T. Spear

Mamm Genome. Author manuscript; available in PMC 2020 Aug 1.

Published in final edited form as: Mamm Genome. 2019 Aug; 30(7-8): 226–236. Published online 2019 Jul 18. doi: 10.1007/s00335-019-09811-6

PMCID:: PMC6761023

Abstract Article PDF–2.6M

Select item 620216811.

Transcription factor Zhx2 deficiency reduces atherosclerosis and promotes macrophage apoptosis in mice

Ayca Erbilgin, Marcus M. Seldin, Xiuju Wu, Margarete Mehrabian, Zhiqiang Zhou, Hongxiu Qi, Keeyon S. Dabirian, René R. Sevag Packard, Wei Hsieh, Steven J. Bensinger, Satyesh Sinha, Aldons J. Lusis

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2018 Sep; 38(9): 2016–2027. doi: 10.1161/ATVBAHA.118.311266

PMCID:: PMC6202168

Abstract Article PDF–1.5M

Select item 551831712.

Zinc Fingers and Homeoboxes 2 (Zhx2) Regulates Sexually Dimorphic Cyp Gene Expression in the Adult Mouse Liver

Kate Townsend Creasy, Jieyun Jiang, Hui Ren, Martha L. Peterson, Brett T. Spear

Gene Expr. 2016; 17(1): 7–17. Published online 2016 May 17. doi: 10.3727/105221616X691712

PMCID:: PMC5518317

Abstract Article PDF–8.5M

Select item 539912313.

Zhx2 (zinc fingers and homeoboxes 2) regulates major urinary protein gene expression in the mouse liver

Jieyun Jiang, Kate Townsend Creasy, Justin Purnell, Martha L. Peterson, Brett T. Spear

J Biol Chem. 2017 Apr 21; 292(16): 6765–6774. Published online 2017 Mar 3. doi: 10.1074/jbc.M116.768275

PMCID:: PMC5399123

Abstract Article PDF–2.2M

Select item 431955914.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 358531415.

Hyperglycemia: GDNF-EGR1 Pathway Target Renal Epithelial Cell Migration and Apoptosis in Diabetic Renal Embryopathy

Ching-Yuang Lin, Tze-Yi Lin, Min-Chun Lee, Shih-Chieh Chen, Jeng-Shou Chang

PLoS One. 2013; 8(2): e56731. Published online 2013 Feb 28. doi: 10.1371/journal.pone.0056731

PMCID:: PMC3585314

Abstract Article PDF–731K

Select item 357241016.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 311015118.

A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58

Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara

Dev Cell. Author manuscript; available in PMC 2011 Jun 7.

Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011

PMCID:: PMC3110151

Abstract Article PDF–2.0M

Select item 284677019.

Quantitative Trait Locus Mapping and Identification of Zhx2 as a Novel Regulator of Plasma Lipid Metabolism

Peter S. Gargalovic, Ayça Erbilgin, Omid Kohannim, Joanne Pagnon, Xuping Wang, Lawrence Castellani, Renee LeBoeuf, Martha L. Peterson, Brett T. Spear, Aldons J. Lusis

Circ Cardiovasc Genet. Author manuscript; available in PMC 2010 Mar 29.

Published in final edited form as: Circ Cardiovasc Genet. 2010 Feb 1; 3(1): 60–67. Published online 2009 Dec 30. doi: 10.1161/CIRCGENETICS.109.902320

PMCID:: PMC2846770

Abstract Article PDF–1.5M

Select item 275968520.

ZHX2 Interacts with Ephrin-B and Regulates Neural Progenitor Maintenance in the Developing Cerebral Cortex

Chen Wu, Runxiang Qiu, Jun Wang, Heying Zhang, Kiyohito Murai, Qiang Lu

J Neurosci. 2009 Jun 10; 29(23): 7404–7412. doi: 10.1523/JNEUROSCI.5841-08.2009

PMCID:: PMC2759685

Abstract Article PDF–4.5M

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