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Items: 1 to 20 of 125

1.
Menin Deficiency Induces Autism‐Like Behaviors by Regulating Foxg1 Transcription and Participates in Foxg1‐Related Encephalopathy
Kai Zhuang, Lige Leng, Xiao Su, Shuzhong Wang, Yuemin Su, Yanbing Chen, Ziqi Yuan, Liu Zi, Jieyin Li, Wenting Xie, Sihan Yan, Yujun Xia, Han Wang, Huifang Li, Zhenyi Chen, Tifei Yuan, Jie Zhang
Adv Sci (Weinh) 2024 Jun; 11(24): 2307953. Published online 2024 Apr 6. doi: 10.1002/advs.202307953
PMCID:
PMC11200012
AbstractArticlePDF–5.0M
2.
Blood-based Proteomic Signatures Associated With MEN1-related Duodenopancreatic Neuroendocrine Tumor Progression
Johannes F Fahrmann, Amanda R Wasylishen, Carolina R C Pieterman, Ehsan Irajizad, Jody Vykoukal, Ranran Wu, Jennifer B Dennison, Christine B Peterson, Hua Zhao, Kim-Anh Do, Daniel M Halperin, Sunita K Agarwal, Jenny E Blau, Smita Jha, Jaydira Del Rivero, Naris Nilubol, Mary F Walter, James M Welch, Lee S Weinstein, Menno R Vriens, Rachel S van Leeuwaarde, Mark J C van Treijen, Gerlof D Valk, Nancy D Perrier, Samir M Hanash, Hiroyuki Katayama
J Clin Endocrinol Metab. 2023 Dec; 108(12): 3260–3271. Published online 2023 Jun 12. doi: 10.1210/clinem/dgad315
PMCID:
PMC11032251
AbstractArticle
3.
Combined deletion of MEN1, ATRX and PTEN triggers development of high-grade pancreatic neuroendocrine tumors in mice
Mary Esmeralda Fuentes, Xiaoyin Lu, Natasha M. Flores, Simone Hausmann, Pawel K. Mazur
Sci Rep. 2024; 14: 8510. Published online 2024 Apr 12. doi: 10.1038/s41598-024-58874-2
PMCID:
PMC11014914
AbstractArticlePDF–1.7M
4.
MEN1 is a regulator of alternative splicing and prevents R-loop-induced genome instability through suppression of RNA polymerase II elongation
Bangming Jin, Jiamei Zhu, Ting Pan, Yunqiao Yang, Li Liang, Yuxia Zhou, Tuo Zhang, Yin Teng, Ziming Wang, Xuyan Wang, Qianting Tian, Bing Guo, Haiyang Li, Tengxiang Chen
Nucleic Acids Res. 2023 Aug 25; 51(15): 7951–7971. Published online 2023 Jul 3. doi: 10.1093/nar/gkad548
PMCID:
PMC10450199
AbstractArticlePDF–2.8M
5.
Clinically Defined Mutations in MEN1 Alter Its Tumor-suppressive Function Through Increased Menin Turnover
Suzann Duan, Sulaiman Sheriff, Uloma B. Elvis-Offiah, Brandon L. Witten, Travis W. Sawyer, Sinju Sundaresan, Tomasz Cierpicki, Jolanta Grembecka, Juanita L. Merchant
Cancer Res Commun. 2023 Jul; 3(7): 1318–1334. Published online 2023 Jul 24. doi: 10.1158/2767-9764.CRC-22-0522
PMCID:
PMC10364643
AbstractArticlePDF–16M
6.
Senescent CD8+ T cells acquire NK cell‐like innate functions to promote antitumor immunity
Toshio Kakuda, Junpei Suzuki, Yuko Matsuoka, Tadahiko Kikugawa, Takashi Saika, Masakatsu Yamashita
Cancer Sci. 2023 Jul; 114(7): 2810–2820. Published online 2023 Apr 25. doi: 10.1111/cas.15824
PMCID:
PMC10323091
AbstractArticlePDF–2.9M
7.
Hypothalamic Menin regulates systemic aging and cognitive decline
Lige Leng, Ziqi Yuan, Xiao Su, Zhenlei Chen, Shangchen Yang, Meiqin Chen, Kai Zhuang, Hui Lin, Hao Sun, Huifang Li, Maoqiang Xue, Jun Xu, Jingqi Yan, Zhenyi Chen, Tifei Yuan, Jie Zhang
PLoS Biol. 2023 Mar; 21(3): e3002033. Published online 2023 Mar 16. doi: 10.1371/journal.pbio.3002033
PMCID:
PMC10019680
AbstractArticlePDF–3.6M
8.
Selective Menin Deletion in the Hippocampal CA1 Region Leads to Disruption of Contextual Memory in the MEN1 Conditional Knockout Mouse: Behavioral Restoration and Gain of Function following the Reintroduction of MEN1 Gene
Anosha Kiran Ulfat, Shadab Batool, Fahad Iqbal, Naweed I. Syed
Cells. 2022 Dec; 11(24): 4019. Published online 2022 Dec 12. doi: 10.3390/cells11244019
PMCID:
PMC9776806
AbstractArticlePDF–8.4M
9.
Thymidylate synthase accelerates Men1-mediated pancreatic tumor progression and reduces survival
Vinod Vijayakurup, Kyungah Maeng, Hye Seung Lee, Benjamin Meyer, Sandra Burkett, Akbar Nawab, Michael W. Dougherty, Christian Jobin, Iqbal Mahmud, Timothy J. Garrett, Michael Feely, Kyoung Bun Lee, Frederic J. Kaye, Maria V. Guijarro, Maria Zajac-Kaye
JCI Insight. 2022 Oct 10; 7(19): e147417. Published online 2022 Oct 10. doi: 10.1172/jci.insight.147417
PMCID:
PMC9675466
AbstractArticlePDF–17M
10.
GFAP-directed Inactivation of Men1 Exploits Glial Cell Plasticity in Favor of Neuroendocrine Reprogramming
Suzann Duan, Travis W. Sawyer, Ricky A. Sontz, Bradley A. Wieland, Andres F. Diaz, Juanita L. Merchant
Cell Mol Gastroenterol Hepatol. 2022; 14(5): 1025–1051. Published online 2022 Jul 11. doi: 10.1016/j.jcmgh.2022.06.009
PMCID:
PMC9490044
AbstractArticlePDF–14M
11.
Context matters – Daxx and Atrx are not robust tumor suppressors in the murine endocrine pancreas
Chang Sun, Jeannelyn S. Estrella, Elizabeth M. Whitley, Gilda P. Chau, Guillermina Lozano, Amanda R. Wasylishen
Dis Model Mech. 2022 Aug 1; 15(8): dmm049552. Published online 2022 Aug 26. doi: 10.1242/dmm.049552
PMCID:
PMC9438929
AbstractArticle
12.
Loss of MEN1 leads to renal fibrosis and decreases HGF‐Adamts5 pathway activity via an epigenetic mechanism
Bangming Jin, Jiamei Zhu, Yuxia Zhou, Li Liang, Yunqiao Yang, Lifen Xu, Tuo Zhang, Po Li, Ting Pan, Bing Guo, Tengxiang Chen, Haiyang Li
Clin Transl Med. 2022 Aug; 12(8): e982. Published online 2022 Aug 15. doi: 10.1002/ctm2.982
PMCID:
PMC9377152
AbstractArticlePDF–21M
13.
Dichotomous Roles of Men1 in Macrophages and Fibroblasts in Bleomycin—Induced Pulmonary Fibrosis
Yuanhua Lu, Jianan Zhao, Yafei Tian, Dan Shao, Zhiqi Zhang, Siqi Li, Jialin Li, Hugang Zhang, Wei Wang, Ping Jiao, Jie Ma
Int J Mol Sci. 2022 May; 23(10): 5385. Published online 2022 May 11. doi: 10.3390/ijms23105385
PMCID:
PMC9140697
AbstractArticlePDF–7.8M
14.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
15.
Menin directs regionalized decidual transformation through epigenetically setting PTX3 to balance FGF and BMP signaling
Mengying Liu, Wenbo Deng, Lu Tang, Meng Liu, Haili Bao, Chuanhui Guo, Changxian Zhang, Jinhua Lu, Haibin Wang, Zhongxian Lu, Shuangbo Kong
Nat Commun. 2022; 13: 1006. Published online 2022 Feb 22. doi: 10.1038/s41467-022-28657-2
PMCID:
PMC8864016
AbstractArticlePDF–9.7M
16.
Exploring the MEN1 dependent modulation of caspase 8 and caspase 3 in human pancreatic and murine embryo fibroblast cells
Nele Wagener, Malte Buchholz, Philippe Bertolino, Chang X. Zhang, Pietro Di Fazio
Apoptosis. 2022; 27(1-2): 70–79. Published online 2021 Dec 8. doi: 10.1007/s10495-021-01700-1
PMCID:
PMC8863690
AbstractArticlePDF–1.2M
17.
The menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML
Emily B. Heikamp, Jill A. Henrich, Florian Perner, Eric M. Wong, Charles Hatton, Yanhe Wen, Sonali P. Barwe, Anilkumar Gopalakrishnapillai, Haiming Xu, Hannah J. Uckelmann, Sumiko Takao, Yaniv Kazansky, Yana Pikman, Gerard M. McGeehan, Edward A. Kolb, Alex Kentsis, Scott A. Armstrong
Blood. 2022 Feb 10; 139(6): 894–906. doi: 10.1182/blood.2021012806
PMCID:
PMC8832476
AbstractArticle
18.
Neuronal Menin Overexpression Rescues Learning and Memory Phenotype in CA1-Specific α7 nAChRs KD Mice
Shadab Batool, Basma Akhter, Jawwad Zaidi, Frank Visser, Gavin Petrie, Matthew Hill, Naweed I. Syed
Cells. 2021 Dec; 10(12): 3286. Published online 2021 Nov 24. doi: 10.3390/cells10123286
PMCID:
PMC8699470
AbstractArticlePDF–15M
19.
MiR-486-3p was downregulated at microRNA profiling of adrenals of multiple endocrine neoplasia type 1 mice, and inhibited human adrenocortical carcinoma cell lines
Su-Chen Li, Azita Monazzam, Masoud Razmara, Xia Chu, Peter Stålberg, Britt Skogseid
Sci Rep. 2021; 11: 14772. Published online 2021 Jul 20. doi: 10.1038/s41598-021-94154-z
PMCID:
PMC8292366
AbstractArticlePDF–1.7M
20.
Spatiotemporal Patterns of Menin Localization in Developing Murine Brain: Co-Expression with the Elements of Cholinergic Synaptic Machinery
Shadab Batool, Jawwad Zaidi, Basma Akhter, Anosha Kiran Ulfat, Frank Visser, Naweed I. Syed
Cells. 2021 May; 10(5): 1215. Published online 2021 May 16. doi: 10.3390/cells10051215
PMCID:
PMC8156519
AbstractArticlePDF–5.0M

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