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Select item 105871411.

Sulforaphane decreases serum selenoprotein P levels through enhancement of lysosomal degradation independent of Nrf2

Xinying Ye, Takashi Toyama, Keiko Taguchi, Kotoko Arisawa, Takayuki Kaneko, Ryouhei Tsutsumi, Masayuki Yamamoto, Yoshiro Saito

Commun Biol. 2023; 6: 1060. Published online 2023 Oct 19. doi: 10.1038/s42003-023-05449-y

PMCID:: PMC10587141

Abstract Article PDF–1.8M

Select item 103133762.

SELENOP modifies sporadic colorectal carcinogenesis and WNT signaling activity through LRP5/6 interactions

Jennifer M. Pilat, Rachel E. Brown, Zhengyi Chen, Nathaniel J. Berle, Adrian P. Othon, M. Kay Washington, Shruti A. Anant, Suguru Kurokawa, Victoria H. Ng, Joshua J. Thompson, Justin Jacobse, Jeremy A. Goettel, Ethan Lee, Yash A. Choksi, Ken S. Lau, Sarah P. Short, Christopher S. Williams

J Clin Invest. 2023 Jul 3; 133(13): e165988. Published online 2023 Jul 3. doi: 10.1172/JCI165988

PMCID:: PMC10313376

Abstract Article PDF–7.9M

Select item 88288553.

Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis

Donghyun Kang, Jeeyeon Lee, Jisu Jung, Bradley A. Carlson, Moon Jong Chang, Chong Bum Chang, Seung-Baik Kang, Byung Cheon Lee, Vadim N. Gladyshev, Dolph L. Hatfield, Byeong Jae Lee, Jin-Hong Kim

Nat Commun. 2022; 13: 779. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28385-7

PMCID:: PMC8828855

Abstract Article PDF–5.2M

Select item 80765594.

Selenoprotein P Modulates Methamphetamine Enhancement of Vesicular Dopamine Release in Mouse Nucleus Accumbens Via Dopamine D2 Receptors

Daniel J. Torres, Jordan T. Yorgason, Catherine C. Mitchell, Ayaka Hagiwara, Marilou A. Andres, Suguru Kurokawa, Scott C. Steffensen, Frederick P. Bellinger

Front Neurosci. 2021; 15: 631825. Published online 2021 Apr 13. doi: 10.3389/fnins.2021.631825

PMCID:: PMC8076559

Abstract Article PDF–1.9M

Select item 80352525.

Colonic epithelial-derived Selenoprotein P is the source for antioxidant-mediated protection in colitis-associated cancer

Sarah P. Short, Jennifer M. Pilat, Caitlyn W. Barrett, Vishruth K. Reddy, Yael Haberman, Jared R. Hendren, Benjamin J. Marsh, Cody E. Keating, Amy K. Motley, Kristina E. Hill, Anne. E. Zemper, M. Kay Washington, Chanjuan Shi, Xi Chen, Keith T. Wilson, Jeffrey S. Hyams, Lee A. Denson, Raymond F. Burk, Michael J. Rosen, Christopher S. Williams

Gastroenterology. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: Gastroenterology. 2021 Apr; 160(5): 1694–1708.e3. Published online 2021 Jan 1. doi: 10.1053/j.gastro.2020.12.059

PMCID:: PMC8035252

Abstract Article PDF–2.7M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 66721537.

Deletion of Apolipoprotein E Receptor-2 in Mice Lowers Brain Selenium and Causes Severe Neurological Dysfunction and Death When a Low-Selenium Diet Is Fed

Raymond F. Burk, Kristina E. Hill, Gary E. Olson, Edwin J. Weeber, Amy K. Motley, Virginia P. Winfrey, Lori M. Austin

J Neurosci. 2007 Jun 6; 27(23): 6207–6211. doi: 10.1523/JNEUROSCI.1153-07.2007

PMCID:: PMC6672153

Abstract Article PDF–112K

Select item 62316388.

Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each

Afzal M. Dogar, Ramona Pauchard-Batschulat, Barbara Grisoni-Neupert, Larry Richman, Alexandra Paillusson, Sylvain Pradervand, Otto Hagenbüchle, Giovanna Ambrosini, Christoph D. Schmid, Philipp Bucher, Lukas C. Kühn

PLoS One. 2018; 13(11): e0206823. Published online 2018 Nov 12. doi: 10.1371/journal.pone.0206823

PMCID:: PMC6231638

Abstract Article PDF–3.8M

Select item 58777399.

Endogenous Selenoprotein P, a Liver-Derived Secretory Protein, Mediates Myocardial Ischemia/Reperfusion Injury in Mice

Hiroshi Chadani, Soichiro Usui, Oto Inoue, Takashi Kusayama, Shin-ichiro Takashima, Takeshi Kato, Hisayoshi Murai, Hiroshi Furusho, Ayano Nomura, Hirofumi Misu, Toshinari Takamura, Shuichi Kaneko, Masayuki Takamura

Int J Mol Sci. 2018 Mar; 19(3): 878. Published online 2018 Mar 16. doi: 10.3390/ijms19030878

PMCID:: PMC5877739

Abstract Article PDF–3.4M

Select item 572744110.

Multiple RNA structures affect translation initiation and UGA redefinition efficiency during synthesis of selenoprotein P

Marco Mariotti, Sumangala Shetty, Lisa Baird, Sen Wu, Gary Loughran, Paul R. Copeland, John F. Atkins, Michael T. Howard

Nucleic Acids Res. 2017 Dec 15; 45(22): 13004–13015. Published online 2017 Oct 23. doi: 10.1093/nar/gkx982

PMCID:: PMC5727441

Abstract Article PDF–2.1M

Select item 513344511.

Human selenoprotein P and S variant mRNAs with different numbers of SECIS elements and inferences from mutant mice of the roles of multiple SECIS elements

Sen Wu, Marco Mariotti, Didac Santesmasses, Kristina E. Hill, Janinah Baclaocos, Estel Aparicio-Prat, Shuping Li, John Mackrill, Yuanyuan Wu, Michael T. Howard, Mario Capecchi, Roderic Guigó, Raymond F. Burk, John F. Atkins

Open Biol. 2016 Nov; 6(11): 160241. Published online 2016 Nov 23. doi: 10.1098/rsob.160241

PMCID:: PMC5133445

Abstract Article PDF–1.1M

Select item 510492912.

Selenoprotein Gene Nomenclature

Vadim N. Gladyshev, Elias S. Arnér, Marla J. Berry, Regina Brigelius-Flohé, Elspeth A. Bruford, Raymond F. Burk, Bradley A. Carlson, Sergi Castellano, Laurent Chavatte, Marcus Conrad, Paul R. Copeland, Alan M. Diamond, Donna M. Driscoll, Ana Ferreiro, Leopold Flohé, Fiona R. Green, Roderic Guigó, Diane E. Handy, Dolph L. Hatfield, John Hesketh, Peter R. Hoffmann, Arne Holmgren, Robert J. Hondal, Michael T. Howard, Kaixun Huang, Hwa-Young Kim, Ick Young Kim, Josef Köhrle, Alain Krol, Gregory V. Kryukov, Byeong Jae Lee, Byung Cheon Lee, Xin Gen Lei, Qiong Liu, Alain Lescure, Alexei V. Lobanov, Joseph Loscalzo, Matilde Maiorino, Marco Mariotti, K. Sandeep Prabhu, Margaret P. Rayman, Sharon Rozovsky, Gustavo Salinas, Edward E. Schmidt, Lutz Schomburg, Ulrich Schweizer, Miljan Simonović, Roger A. Sunde, Petra A. Tsuji, Susan Tweedie, Fulvio Ursini, Philip D. Whanger, Yan Zhang

J Biol Chem. 2016 Nov 11; 291(46): 24036–24040. Published online 2016 Sep 19. doi: 10.1074/jbc.M116.756155

PMCID:: PMC5104929

Abstract Article PDF–140K

Select item 464900513.

Competition between the Brain and Testes under Selenium-Compromised Conditions: Insight into Sex Differences in Selenium Metabolism and Risk of Neurodevelopmental Disease

Matthew W. Pitts, Penny M. Kremer, Ann C. Hashimoto, Daniel J. Torres, China N. Byrns, Christopher S. Williams, Marla J. Berry

J Neurosci. 2015 Nov 18; 35(46): 15326–15338. doi: 10.1523/JNEUROSCI.2724-15.2015

PMCID:: PMC4649005

Abstract Article PDF–6.3M

Select item 456367214.

Selenoprotein P influences colitis-induced tumorigenesis by mediating stemness and oxidative damage

Caitlyn W. Barrett, Vishruth K. Reddy, Sarah P. Short, Amy K. Motley, Mary K. Lintel, Amber M. Bradley, Tanner Freeman, Jefferson Vallance, Wei Ning, Bobak Parang, Shenika V. Poindexter, Barbara Fingleton, Xi Chen, Mary K. Washington, Keith T. Wilson, Noah F. Shroyer, Kristina E. Hill, Raymond F. Burk, Christopher S. Williams

J Clin Invest. 2015 Jul 1; 125(7): 2646–2660. Published online 2015 Jun 8. doi: 10.1172/JCI76099

PMCID:: PMC4563672

Abstract Article PDF–3.3M

Select item 431955915.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 411611016.

Secisbp2 Is Essential for Embryonic Development and Enhances Selenoprotein Expression

Sandra Seeher, Tarik Atassi, Yassin Mahdi, Bradley A. Carlson, Doreen Braun, Eva K. Wirth, Marc O. Klein, Nathalie Reix, Angela C. Miniard, Lutz Schomburg, Dolph L. Hatfield, Donna M. Driscoll, Ulrich Schweizer

Antioxid Redox Signal. 2014 Aug 20; 21(6): 835–849. doi: 10.1089/ars.2013.5358