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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107693502.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 106264253.

Cytotoxic T lymphocytes require transcription for infiltration but not target cell lysis

Arianne C Richard, Claire Y Ma, John C Marioni, Gillian M Griffiths

EMBO Rep. 2023 Nov; 24(11): e57653. Published online 2023 Oct 20. doi: 10.15252/embr.202357653

PMCID:: PMC10626425

Abstract Article PDF–1.8M

Select item 102667824.

RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia

Jian-Gang Ren, Bowen Xing, Kaosheng Lv, Rachel A. O’Keefe, Mengfang Wu, Ruoxing Wang, Kaylyn M. Bauer, Arevik Ghazaryan, George M. Burslem, Jing Zhang, Ryan M. O’Connell, Vinodh Pillai, Elizabeth O. Hexner, Mark R. Philips, Wei Tong

J Clin Invest. 2023 Jun 15; 133(12): e165510. Published online 2023 Jun 15. doi: 10.1172/JCI165510

PMCID:: PMC10266782

Abstract Article PDF–2.8M

Select item 96755665.

CD11c⁺ myeloid cell exosomes reduce intestinal inflammation during colitis

Kaylyn M. Bauer, Morgan C. Nelson, William W. Tang, Tyson R. Chiaro, D. Garrett Brown, Arevik Ghazaryan, Soh-Hyun Lee, Allison M. Weis, Jennifer H. Hill, Kendra A. Klag, Van B. Tran, Jacob W. Thompson, Andrew G. Ramstead, Josh K. Monts, James E. Marvin, Margaret Alexander, Warren P. Voth, W. Zac Stephens, Diane M. Ward, Aaron C. Petrey, June L. Round, Ryan M. O’Connell

JCI Insight. 2022 Oct 10; 7(19): e159469. Published online 2022 Oct 10. doi: 10.1172/jci.insight.159469

PMCID:: PMC9675566

Abstract Article PDF–11M

Select item 95552326.

Rabphilin3A reduces integrin-dependent growth cone signaling to restrict axon regeneration after trauma

Yuichi Sekine, Ramakrishnan Kannan, Xingxing Wang, Stephen M. Strittmatter

Exp Neurol. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: Exp Neurol. 2022 Jul; 353: 114070. Published online 2022 Apr 7. doi: 10.1016/j.expneurol.2022.114070

PMCID:: PMC9555232

Abstract Article PDF–3.3M

Select item 91978487.

Deletion in chromosome 6 spanning alpha-synuclein and multimerin1 loci in the Rab27a/b double knockout mouse

Rudradip Pattanayak, Rachel Underwood, Michael R. Crowley, David K. Crossman, Jennifer R. Morgan, Talene A. Yacoubian

Sci Rep. 2022; 12: 9837. Published online 2022 Jun 14. doi: 10.1038/s41598-022-13557-8

PMCID:: PMC9197848

Abstract Article PDF–2.2M

Select item 83360088.

FOXO1-Mediated Downregulation of RAB27B Leads to Decreased Exosome Secretion in Diabetic Kidneys

Mengru Zeng, Jin Wen, Zhengwei Ma, Li Xiao, Yutao Liu, Sangho Kwon, Yu Liu, Zheng Dong

Diabetes. 2021 Jul; 70(7): 1536–1548. Published online 2021 Feb 17. doi: 10.2337/db20-1108

PMCID:: PMC8336008

Abstract Article PDF–2.2M

Select item 74608189.

Inhibition of Rab27a and Rab27b Has Opposite Effects on the Regulation of Hair Cycle and Hair Growth

Kyung-Eun Ku, Nahyun Choi, Jong-Hyuk Sung

Int J Mol Sci. 2020 Aug; 21(16): 5672. Published online 2020 Aug 7. doi: 10.3390/ijms21165672

PMCID:: PMC7460818

Abstract Article PDF–3.6M

Select item 732199110.

A hypoxia-induced Rab pathway regulates embryo implantation by controlled trafficking of secretory granules

Arpita Bhurke, Athilakshmi Kannan, Alison Neff, Qiuyan Ma, Mary J. Laws, Robert N. Taylor, Milan K. Bagchi, Indrani C. Bagchi

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14532–14542. Published online 2020 Jun 8. doi: 10.1073/pnas.2000810117

PMCID:: PMC7321991

Abstract Article PDF–2.4M

Select item 719555811.

Actions of Rab27B‐GTPase on mammalian central excitatory synaptic transmission

Erwin R. Arias‐Hervert, Nicole Xu, Meredith Njus, Geoff G. Murphy, Yanan Hou, John A. Williams, Stephen I. Lentz, Stephen A. Ernst, Edward L. Stuenkel

Physiol Rep. 2020 May; 8(9): e14428. Published online 2020 May 1. doi: 10.14814/phy2.14428

PMCID:: PMC7195558

Abstract Article PDF–1.6M

Select item 623163812.

Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each

Afzal M. Dogar, Ramona Pauchard-Batschulat, Barbara Grisoni-Neupert, Larry Richman, Alexandra Paillusson, Sylvain Pradervand, Otto Hagenbüchle, Giovanna Ambrosini, Christoph D. Schmid, Philipp Bucher, Lukas C. Kühn

PLoS One. 2018; 13(11): e0206823. Published online 2018 Nov 12. doi: 10.1371/journal.pone.0206823

PMCID:: PMC6231638

Abstract Article PDF–3.8M

Select item 593771613.

Functional Genome-wide Screen Identifies Pathways Restricting Central Nervous System Axonal Regeneration

Yuichi Sekine, Alexander Lin-Moore, Devon M. Chenette, Xingxing Wang, Zhaoxin Jiang, William B. Cafferty, Marc Hammarlund, Stephen M. Strittmatter

Cell Rep. Author manuscript; available in PMC 2018 May 7.

Published in final edited form as: Cell Rep. 2018 Apr 10; 23(2): 415–428. doi: 10.1016/j.celrep.2018.03.058

Correction in:: Cell Rep. 2018 Jul 3; 24(1): 269.

PMCID:: PMC5937716

Abstract Article PDF–2.0M

Select item 582122714.

Rab27-dependent exosome production inhibits chronic inflammation and enables acute responses to inflammatory stimuli

Margaret Alexander, Andrew G. Ramstead, Kaylyn M. Bauer, Soh-Hyun Lee, Marah C. Runtsch, Jared Wallace, Thomas B. Huffaker, Dane K. Larsen, Tanya Tolmachova, Miguel C. Seabra, June L. Round, Diane M. Ward, Ryan M. O’Connell

J Immunol. Author manuscript; available in PMC 2018 Nov 15.

Published in final edited form as: J Immunol. 2017 Nov 15; 199(10): 3559–3570. Published online 2017 Oct 4. doi: 10.4049/jimmunol.1700904

PMCID:: PMC5821227

Abstract Article PDF–2.5M

Select item 565930515.

Collaboration between distinct Rab small GTPase trafficking circuits mediates bacterial clearance from the bladder epithelium

Yuxuan Miao, Pradeep Bist, Jianxuan Wu, Qing Zhao, Qi-jing Li, Ying Wan, Soman N. Abraham

Cell Host Microbe. Author manuscript; available in PMC 2018 Sep 13.

Published in final edited form as: Cell Host Microbe. 2017 Sep 13; 22(3): 330–342.e4. doi: 10.1016/j.chom.2017.08.002

PMCID:: PMC5659305

Abstract Article PDF–858K

Select item 550326116.

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program

John P. Sundberg, Soheil S. Dadras, Kathleen A. Silva, Victoria E. Kennedy, Gaven Garland, Stephen A. Murray, Beth A. Sundberg, Paul N. Schofield, C. Herbert Pratt

PLoS One. 2017; 12(7): e0180682. Published online 2017 Jul 10. doi: 10.1371/journal.pone.0180682

PMCID:: PMC5503261

Abstract Article PDF–31M

Select item 537450017.

Sedentary lifestyle related exosomal release of Hotair from gluteal-femoral fat promotes intestinal cell proliferation

Xiaozhao Lu, Danna Bai, Xiangwei Liu, Chen Zhou, Guodong Yang

Sci Rep. 2017; 7: 45648. Published online 2017 Mar 31. doi: 10.1038/srep45648

PMCID:: PMC5374500

Abstract Article PDF–1.6M

Select item 529582118.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 508465019.

Kinesin-1 controls mast cell degranulation and anaphylaxis through PI3K-dependent recruitment to the granular Slp3/Rab27b complex

Isabelle Munoz, Luca Danelli, Julien Claver, Nicolas Goudin, Mathieu Kurowska, Iris Karina Madera-Salcedo, Jian-Dong Huang, Alain Fischer, Claudia González-Espinosa, Geneviéve de Saint Basile, Ulrich Blank, Gaël Ménasché

J Cell Biol. 2016 Oct 24; 215(2): 203–216. doi: 10.1083/jcb.201605073

PMCID:: PMC5084650

Abstract Article PDF–2.8M

Select item 493520220.

Imbalanced Rab3D versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjögren's Syndrome

Zhen Meng, Maria C. Edman, Pang-Yu Hsueh, Chiao-Yu Chen, Wannita Klinngam, Tanya Tolmachova, Curtis T. Okamoto, Sarah F. Hamm-Alvarez

Am J Physiol Cell Physiol. 2016 Jun 1; 310(11): C942–C954. Published online 2016 Apr 13. doi: 10.1152/ajpcell.00275.2015

PMCID:: PMC4935202

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