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Select item 114967271.

Functional bias of contractile control in mouse resistance arteries

Nadia Haghbin, David M. Richter, Sanjay Kharche, Michelle S. M. Kim, Donald G. Welsh

Sci Rep. 2024; 14: 24940. Published online 2024 Oct 22. doi: 10.1038/s41598-024-75838-8

PMCID:: PMC11496727

Abstract Article PDF–5.0M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 105168843.

Electric field stimulation unmasks a subtle role for T-type calcium channels in regulating lymphatic contraction

Michael J. Davis, Jorge A. Castorena-Gonzalez, Scott D. Zawieja

Sci Rep. 2023; 13: 15862. Published online 2023 Sep 22. doi: 10.1038/s41598-023-42877-6

PMCID:: PMC10516884

Abstract Article PDF–1.7M

Select item 98982234.

Ca_V3.1 T-type calcium channels are important for spatial memory processing in the dorsal subiculum

Srdjan M. Joksimovic, Seyed Mohammadreza Ghodsi, Jasper A. Heinsbroek, James E. Orfila, Nicolas Busquet, Vesna Tesic, Robert Valdez, Brier Fine-Raquet, Vesna Jevtovic-Todorovic, Yogendra H. Raol, Paco S. Herson, Slobodan M. Todorovic

Neuropharmacology. Author manuscript; available in PMC 2024 Mar 15.

Published in final edited form as: Neuropharmacology. 2023 Mar 15; 226: 109400. Published online 2022 Dec 29. doi: 10.1016/j.neuropharm.2022.109400

PMCID:: PMC9898223

Abstract Article PDF–2.1M

Select item 86109745.

Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation

Rin Khang, Areum Jo, Hojin Kang, Hanna Kim, Eunsang Kwag, Ji-Yeong Lee, Okjae Koo, Jinsu Park, Hark Kyun Kim, Dong-Gyu Jo, Inwoo Hwang, Jee-Yin Ahn, Yunjong Lee, Jeong-Yun Choi, Yun-Song Lee, Joo-Ho Shin

Sci Rep. 2021; 11: 22745. Published online 2021 Nov 23. doi: 10.1038/s41598-021-02218-x

PMCID:: PMC8610974

Abstract Article PDF–2.5M

Select item 78649586.

Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures

Anikó Rátkai, Krisztián Tárnok, Hajar El Aouad, Brigitta Micska, Katalin Schlett, Attila Szücs

Sci Rep. 2021; 11: 3236. Published online 2021 Feb 5. doi: 10.1038/s41598-021-82775-3

PMCID:: PMC7864958

Abstract Article PDF–5.4M

Select item 77825897.

QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function

Xinyun Chen, Ying Liu, Chen Xu, Lina Ba, Zhuo Liu, Xiuya Li, Jie Huang, Ed Simpson, Hongyu Gao, Dayan Cao, Wei Sheng, Hanping Qi, Hongrui Ji, Maria Sanderson, Chen-Leng Cai, Xiaohui Li, Lei Yang, Jie Na, Kenichi Yamamura, Yunlong Liu, Guoying Huang, Weinian Shou, Ning Sun

Nat Commun. 2021; 12: 89. Published online 2021 Jan 4. doi: 10.1038/s41467-020-20327-5

PMCID:: PMC7782589

Abstract Article PDF–8.6M

Select item 77258068.

Global genetic deletion of Ca_V3.3 channels facilitates anaesthetic induction and enhances isoflurane-sparing effects of T-type calcium channel blockers

Simon Feseha, Tamara Timic Stamenic, Damon Wallace, Caesare Tamag, Lingling Yang, Jen Q. Pan, Slobodan M. Todorovic

Sci Rep. 2020; 10: 21510. Published online 2020 Dec 9. doi: 10.1038/s41598-020-78488-8

PMCID:: PMC7725806

Abstract Article PDF–4.4M

Select item 76423059.

Concomitant genetic ablation of L-type Ca_v1.3 (α_1D) and T-type Ca_v3.1 (α_1G) Ca²⁺ channels disrupts heart automaticity

Matthias Baudot, Eleonora Torre, Isabelle Bidaud, Julien Louradour, Angelo G. Torrente, Lucile Fossier, Leïla Talssi, Joël Nargeot, Stéphanie Barrère-Lemaire, Pietro Mesirca, Matteo E. Mangoni

Sci Rep. 2020; 10: 18906. Published online 2020 Nov 3. doi: 10.1038/s41598-020-76049-7

PMCID:: PMC7642305

Abstract Article PDF–12M

Select item 747364910.

TCF7L2 regulates postmitotic differentiation programmes and excitability patterns in the thalamus

Marcin Andrzej Lipiec, Joanna Bem, Kamil Koziński, Chaitali Chakraborty, Joanna Urban-Ciećko, Tomasz Zajkowski, Michał Dąbrowski, Łukasz Mateusz Szewczyk, Angel Toval, José Luis Ferran, Andrzej Nagalski, Marta Barbara Wiśniewska

Development. 2020 Aug 15; 147(16): dev190181. Published online 2020 Aug 25. doi: 10.1242/dev.190181

PMCID:: PMC7473649

Abstract Article

Select item 741416211.

T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system

Rajiv A. Mohan, Fernanda M. Bosada, Jan H. van Weerd, Karel van Duijvenboden, Jianan Wang, Mathilda T. M. Mommersteeg, Ingeborg B. Hooijkaas, Vincent Wakker, Corrie de Gier-de Vries, Ruben Coronel, Gerard J. J. Boink, Jeroen Bakkers, Phil Barnett, Bas J. Boukens, Vincent M. Christoffels

Proc Natl Acad Sci U S A. 2020 Aug 4; 117(31): 18617–18626. Published online 2020 Jul 16. doi: 10.1073/pnas.1919379117

PMCID:: PMC7414162

Abstract Article PDF–1.7M

Select item 736566412.

Trait-associated noncoding variant regions affect TBX3 regulation and cardiac conduction

Jan Hendrik van Weerd, Rajiv A Mohan, Karel van Duijvenboden, Ingeborg B Hooijkaas, Vincent Wakker, Bastiaan J Boukens, Phil Barnett, Vincent M Christoffels

eLife. 2020; 9: e56697. Published online 2020 Jul 16. doi: 10.7554/eLife.56697

PMCID:: PMC7365664

Abstract Article PDF–1.8M

Select item 730003513.

Inhibition of G protein-gated K⁺ channels by tertiapin-Q rescues sinus node dysfunction and atrioventricular conduction in mouse models of primary bradycardia

Isabelle Bidaud, Antony Chung You Chong, Agnes Carcouet, Stephan De Waard, Flavien Charpentier, Michel Ronjat, Michel De Waard, Dirk Isbrandt, Kevin Wickman, Anne Vincent, Matteo E. Mangoni, Pietro Mesirca

Sci Rep. 2020; 10: 9835. Published online 2020 Jun 17. doi: 10.1038/s41598-020-66673-8

PMCID:: PMC7300035

Abstract Article PDF–1.8M

Select item 726920114.

A missense mutation of ErbB2 produces a novel mouse model of stillbirth associated with a cardiac abnormality but lacking abnormalities of placental structure

Heba Shawer, Esther Aiyelaagbe, Christopher Clowes, Samantha C. Lean, Yinhui Lu, Karl E. Kadler, Alan Kerby, Mark R. Dilworth, Kathryn E. Hentges, Alexander E. P. Heazell

PLoS One. 2020; 15(6): e0233007. Published online 2020 Jun 3. doi: 10.1371/journal.pone.0233007