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Items: 1 to 20 of 50

1.
DUSP4 modulates RIG-I- and STING-mediated IRF3-type I IFN response
Huipeng Jiao, Sharmy J. James, Chin Wen Png, Chaoyu Cui, Heng Li, Liang Li, Wan Ni Chia, Nyo Min, Weiyun Li, Carla Claser, Laurent Rénia, Hongyan Wang, Mark I-Cheng Chen, Justin Jang Hann Chu, Kevin Shyong Wei Tan, Yinyue Deng, Yongliang Zhang
Cell Death Differ. 2024 Mar; 31(3): 280–291. Published online 2024 Feb 21. doi: 10.1038/s41418-024-01269-7
PMCID:
PMC10923883
AbstractArticlePDF–2.8M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer’s Disease
Erming Wang, Allen L. Pan, Pritha Bagchi, Srikant Rangaraju, Nicholas T. Seyfried, Michelle E. Ehrlich, Stephen R. Salton, Bin Zhang
Biomolecules. 2024 Jan; 14(1): 66. Published online 2024 Jan 3. doi: 10.3390/biom14010066
PMCID:
PMC10813059
AbstractArticlePDF–3.9M
4.
Identification of DUSP4/6 overexpression as a potential rheostat to NRAS-induced hepatocarcinogenesis
Sophie Klemm, Katja Evert, Kirsten Utpatel, Alexandra Muggli, Maria M. Simile, Xin Chen, Matthias Evert, Diego F. Calvisi, Alexander Scheiter
BMC Cancer. 2023; 23: 1086. Published online 2023 Nov 9. doi: 10.1186/s12885-023-11577-9
PMCID:
PMC10636894
AbstractArticlePDF–4.0M
5.
Feto-maternal cholesterol transport regulated by β-Klotho–FGF15 axis is essential for fetal growth
Kanako Kobayashi, Kazuko Iwasa, Rika Azuma-Suzuki, Takeshi Kawauchi, Yo-ichi Nabeshima
Life Sci Alliance. 2023 Oct; 6(10): e202301916. Published online 2023 Aug 4. doi: 10.26508/lsa.202301916
PMCID:
PMC10403640
AbstractArticlePDF–2.1M
6.
Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces β-Amyloid Load in Males and Females
Allen L. Pan, Mickael Audrain, Emmy Sakakibara, Rajeev Joshi, Xiaodong Zhu, Qian Wang, Minghui Wang, Noam D. Beckmann, Eric E. Schadt, Sam Gandy, Bin Zhang, Michelle E. Ehrlich, Stephen R. Salton
Cells. 2022 Dec; 11(23): 3880. Published online 2022 Dec 1. doi: 10.3390/cells11233880
PMCID:
PMC9737364
AbstractArticlePDF–5.6M
7.
Metabolic Impact of MKP-2 Upregulation in Obesity Promotes Insulin Resistance and Fatty Liver Disease
Savanie Fernando, Jacob Sellers, Shauri Smith, Sarayu Bhogoju, Sadie Junkins, Morgan Welch, Orion Willoughby, Nabin Ghimire, Cassandra Secunda, Marina Barmanova, Sean C. Kumer, Kisuk Min, Ahmed Lawan
Nutrients. 2022 Jun; 14(12): 2475. Published online 2022 Jun 15. doi: 10.3390/nu14122475
PMCID:
PMC9228271
AbstractArticlePDF–3.5M
8.
NANOG initiates epiblast fate through the coordination of pluripotency genes expression
Nicolas Allègre, Sabine Chauveau, Cynthia Dennis, Yoan Renaud, Dimitri Meistermann, Lorena Valverde Estrella, Pierre Pouchin, Michel Cohen-Tannoudji, Laurent David, Claire Chazaud
Nat Commun. 2022; 13: 3550. Published online 2022 Jun 21. doi: 10.1038/s41467-022-30858-8
PMCID:
PMC9213552
AbstractArticlePDF–4.4M
9.
MEK-inhibitor-mediated rescue of skeletal myopathy caused by activating Hras mutation in a Costello syndrome mouse model
William E. Tidyman, Alice F. Goodwin, Yoshiko Maeda, Ophir D. Klein, Katherine A. Rauen
Dis Model Mech. 2022 Feb 1; 15(2): dmm049166. Published online 2021 Nov 19. doi: 10.1242/dmm.049166
PMCID:
PMC8617311
AbstractArticle
10.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
11.
A β-catenin gradient links the clock and wavefront systems in mouse embryo segmentation
Alexander Aulehla, Winfried Wiegraebe, Valerie Baubet, Matthias B. Wahl, Chuxia Deng, Makoto Taketo, Mark Lewandoski, Olivier Pourquié
Nat Cell Biol. Author manuscript; available in PMC 2020 Jul 30.
Published in final edited form as: Nat Cell Biol. 2008 Feb; 10(2): 186–193. Published online 2007 Dec 23. doi: 10.1038/ncb1679
PMCID:
PMC7391962
AbstractArticlePDF–1.6M
12.
Whole Genome Microarray Analysis of DUSP4-Deletion Reveals A Novel Role for MAP Kinase Phosphatase-2 (MKP-2) in Macrophage Gene Expression and Function
Thikryat Neamatallah, Shilan Jabbar, Rothwelle Tate, Juliane Schroeder, Muhannad Shweash, James Alexander, Robin Plevin
Int J Mol Sci. 2019 Jul; 20(14): 3434. Published online 2019 Jul 12. doi: 10.3390/ijms20143434
PMCID:
PMC6679025
AbstractArticlePDF–2.2M
13.
Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss
Adelaida M Celaya, Isabel Sánchez-Pérez, Jose M Bermúdez-Muñoz, Lourdes Rodríguez-de la Rosa, Laura Pintado-Berninches, Rosario Perona, Silvia Murillo-Cuesta, Isabel Varela-Nieto
eLife. 2019; 8: e39159. Published online 2019 Apr 2. doi: 10.7554/eLife.39159
PMCID:
PMC6464786
AbstractArticlePDF–5.9M
14.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
15.
Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling
Ryan Hamnett, Priya Crosby, Johanna E. Chesham, Michael H. Hastings
Nat Commun. 2019; 10: 542. Published online 2019 Feb 1. doi: 10.1038/s41467-019-08427-3
PMCID:
PMC6358603
AbstractArticlePDF–7.2M
16.
Novel protective role for MAP kinase phosphatase 2 in inflammatory arthritis
Juliane Schroeder, Kirsty Ross, Kathryn McIntosh, Shilan Jabber, Stuart Woods, Jenny Crowe, Janet Patterson Kane, James Alexander, Catherine Lawrence, Robin Plevin
RMD Open. 2019; 5(1): e000711. Published online 2019 Jan 11. doi: 10.1136/rmdopen-2018-000711
PMCID:
PMC6340532
AbstractArticlePDF–4.4M
17.
Compound haploinsufficiency of Dok2 and Dusp4 promotes lung tumorigenesis
Ming Chen, Jiangwen Zhang, Alice H. Berger, Moussa S. Diolombi, Christopher Ng, Jacqueline Fung, Roderick T. Bronson, Mireia Castillo-Martin, Tin Htwe Thin, Carlos Cordon-Cardo, Robin Plevin, Pier Paolo Pandolfi
J Clin Invest. 2019 Jan 2; 129(1): 215–222. Published online 2018 Nov 26. doi: 10.1172/JCI99699
PMCID:
PMC6307955
AbstractArticlePDF–9.3M
18.
Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival
Jason C Choi, Wei Wu, Elizabeth Phillips, Robin Plevin, Fusako Sera, Shunichi Homma, Howard J Worman
Hum Mol Genet. 2018 Jul 1; 27(13): 2290–2305. Published online 2018 Apr 16. doi: 10.1093/hmg/ddy134
PMCID:
PMC6005151
AbstractArticlePDF–1.2M
19.
Unrestrained p38 MAPK Activation in Dusp1/4 Double Null Mice Induces Cardiomyopathy
Mannix Auger-Messier, Federica Accornero, Sanjeewa A. Goonasekera, Orlando F. Bueno, John N. Lorenz, Jop H. van Berlo, Robert N. Willette, Jeffery D. Molkentin
Circ Res. Author manuscript; available in PMC 2018 May 1.
Published in final edited form as: Circ Res. 2013 Jan 4; 112(1): 48–56. Published online 2012 Sep 19. doi: 10.1161/CIRCRESAHA.112.272963
PMCID:
PMC5929162
AbstractArticlePDF–1.3M
20.
Convergence of BMI1 and CHD7 on ERK Signaling in Medulloblastoma
Sara Badodi, Adrian Dubuc, Xinyu Zhang, Gabriel Rosser, Mariane Da Cunha Jaeger, Michelle M. Kameda-Smith, Anca Sorana Morrissy, Paul Guilhamon, Philipp Suetterlin, Xiao-Nan Li, Loredana Guglielmi, Ashirwad Merve, Hamza Farooq, Mathieu Lupien, Sheila K. Singh, M. Albert Basson, Michael D. Taylor, Silvia Marino
Cell Rep. 2017 Dec 5; 21(10): 2772–2784. Published online 2017 Dec 5. doi: 10.1016/j.celrep.2017.11.021
PMCID:
PMC5732319
AbstractArticle

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