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Select item 114526231.

The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development

Pablo Gómez-del Arco, Joan Isern, Daniel Jimenez-Carretero, Dolores López-Maderuelo, Rebeca Piñeiro-Sabarís, Fadoua El Abdellaoui-Soussi, Carlos Torroja, María Linarejos Vera-Pedrosa, Mercedes Grima-Terrén, Alberto Benguria, Ana Simón-Chica, Antonio Queiro-Palou, Ana Dopazo, Fátima Sánchez-Cabo, José Jalife, José Luis de la Pompa, David Filgueiras-Rama, Pura Muñoz-Cánoves, Juan Miguel Redondo

Nat Commun. 2024; 15: 8602. Published online 2024 Oct 4. doi: 10.1038/s41467-024-52809-1

PMCID:: PMC11452623

Abstract Article PDF–4.1M

Select item 114156002.

PRDM16 determines specification of ventricular cardiomyocytes by suppressing alternative cell fates

Jore Van Wauwe, Alexia Mahy, Sander Craps, Samaneh Ekhteraei-Tousi, Pieter Vrancaert, Hannelore Kemps, Wouter Dheedene, Rosa Doñate Puertas, Sander Trenson, H. Llewelyn Roderick, Manu Beerens, Aernout Luttun

Life Sci Alliance. 2024 Dec; 7(12): e202402719. Published online 2024 Sep 20. doi: 10.26508/lsa.202402719

PMCID:: PMC11415600

Abstract Article PDF–5.1M

Select item 113736213.

Transcriptome analysis reveals EBF1 ablation-induced injuries in cardiac system

Yueheng Wu, Shaoxian Chen, Guiping Huang, Lu Zhang, Liying Zhong, Yi Feng, Pengju Wen, Juli Liu

Theranostics. 2024; 14(12): 4894–4915. Published online 2024 Aug 12. doi: 10.7150/thno.92060

PMCID:: PMC11373621

Abstract Article PDF–12M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 103593775.

KCNE1 does not shift TMEM16A from a Ca²⁺ dependent to a voltage dependent Cl^- channel and is not expressed in renal proximal tubule

Khaoula Talbi, Jiraporn Ousingsawat, Raquel Centeio, Rainer Schreiber, Karl Kunzelmann

Pflugers Arch. 2023; 475(8): 995–1007. Published online 2023 Jul 13. doi: 10.1007/s00424-023-02829-5

PMCID:: PMC10359377

Abstract Article PDF–3.8M

Select item 102530026.

TCF7L1 Controls the Differentiation of Tuft Cells in Mouse Small Intestine

Valeriya V. Zinina, Melanie Sauer, Lira Nigmatullina, Nastasja Kreim, Natalia Soshnikova

Cells. 2023 Jun; 12(11): 1452. Published online 2023 May 23. doi: 10.3390/cells12111452

PMCID:: PMC10253002

Abstract Article PDF–2.4M

Select item 86492777.

LAMP2 Cardiomyopathy: Consequences of Impaired Autophagy in the Heart

Ronny Alcalai, Michael Arad, Hiroko Wakimoto, Dor Yadin, Joshua Gorham, Libin Wang, Elia Burns, Barry J. Maron, William C. Roberts, Tetsuo Konno, David A. Conner, Antonio R. Perez‐Atayde, Jon G. Seidman, Christine E. Seidman

J Am Heart Assoc. 2021 Sep 7; 10(17): e018829. Published online 2021 Aug 28. doi: 10.1161/JAHA.120.018829

PMCID:: PMC8649277

Abstract Article PDF–1.8M

Select item 78468458.

Gene therapy via canalostomy approach preserves auditory and vestibular functions in a mouse model of Jervell and Lange-Nielsen syndrome type 2

Xuewen Wu, Li Zhang, Yihui Li, Wenjuan Zhang, Jianjun Wang, Cuiyun Cai, Xi Lin

Nat Commun. 2021; 12: 697. Published online 2021 Jan 29. doi: 10.1038/s41467-020-20808-7

PMCID:: PMC7846845

Abstract Article PDF–3.5M

Select item 66332859.

Critical Roles of Transitional Cells and Na/K-ATPase in the Formation of Vestibular Endolymph

Sylvain Bartolami, Sophie Gaboyard, Julie Quentin, Cécile Travo, Mélanie Cavalier, Jacques Barhanin, Christian Chabbert

J Neurosci. 2011 Nov 16; 31(46): 16541–16549. doi: 10.1523/JNEUROSCI.2430-11.2011

PMCID:: PMC6633285

Abstract Article PDF–1.8M

Select item 651942810.

Long QT mutations at the interface between KCNQ1 helix C and KCNE1 disrupt I_KS regulation by PKA and PIP₂

Meidan Dvir, Roi Strulovich, Dana Sachyani, Inbal Ben-Tal Cohen, Yoni Haitin, Carmen Dessauer, Olaf Pongs, Robert Kass, Joel A. Hirsch, Bernard Attali

J Cell Sci. 2014 Sep 15; 127(18): 3943–3955. Published online 2014 Sep 14. doi: 10.1242/jcs.147033

PMCID:: PMC6519428

Abstract Article

Select item 609918511.

Mechanism Sharing Between Genetic and Gestational Hypoxia-Induced Cardiac Anomalies

Olivia Moumne, Rajib Chowdhurry, Cassandra Doll, Natalia Pereira, Mustafa Hashimi, Tabor Grindrod, James J. Dollar, Alberto Riva, Hideko Kasahara

Front Cardiovasc Med. 2018; 5: 100. Published online 2018 Aug 13. doi: 10.3389/fcvm.2018.00100

PMCID:: PMC6099185

Abstract Article PDF–2.7M

Select item 562517612.

Remodeling of repolarization and arrhythmia susceptibility in a myosin-binding protein C knockout mouse model

Amir Toib, Chen Zhang, Giulia Borghetti, Xiaoxiao Zhang, Markus Wallner, Yijun Yang, Constantine D. Troupes, Hajime Kubo, Thomas E. Sharp, Eric Feldsott, Remus M. Berretta, Neil Zalavadia, Danielle M. Trappanese, Shavonn Harper, Polina Gross, Xiongwen Chen, Sadia Mohsin, Steven R. Houser

Am J Physiol Heart Circ Physiol. 2017 Sep 1; 313(3): H620–H630. Published online 2017 Jun 23. doi: 10.1152/ajpheart.00167.2017

PMCID:: PMC5625176

Abstract Article

Select item 555904213.

SUMOylation determines the voltage required to activate cardiac I_Ks channels

Dazhi Xiong, Tian Li, Hui Dai, Anthony F. Arena, Leigh D. Plant, Steve A. N. Goldstein

Proc Natl Acad Sci U S A. 2017 Aug 8; 114(32): E6686–E6694. Published online 2017 Jul 25. doi: 10.1073/pnas.1706267114

PMCID:: PMC5559042

Abstract Article PDF–1.3M

Select item 491701014.

KCNE1 and KCNE3: the yin and yang of voltage-gated K⁺ channel regulation

Geoffrey W. Abbott

Gene. Author manuscript; available in PMC 2017 Jan 15.

Published in final edited form as: Gene. 2016 Jan 15; 576(1 Pt 1): 1–13. Published online 2015 Sep 26. doi: 10.1016/j.gene.2015.09.059

PMCID:: PMC4917010

Abstract Article PDF–851K

Select item 430172415.

MyoR Modulates Cardiac Conduction by Repressing Gata4

John P. Harris, Minoti Bhakta, Svetlana Bezprozvannaya, Lin Wang, Christina Lubczyk, Eric N. Olson, Nikhil V. Munshi

Mol Cell Biol. 2015 Feb; 35(4): 649–661. Prepublished online 2014 Dec 8. Published online 2015 Jan 23. doi: 10.1128/MCB.00860-14

PMCID:: PMC4301724

Abstract Article PDF–2.0M

Select item 365936416.

BACE1 and presenilin/γ-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels

Carolyn C. Sachse, Young Hye Kim, Marianne Agsten, Tobias Huth, Christian Alzheimer, Dora M. Kovacs, Doo Yeon Kim

FASEB J. 2013 Jun; 27(6): 2458–2467. doi: 10.1096/fj.12-214056

PMCID:: PMC3659364

Abstract Article

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 317188118.

O-glycosylation of the cardiac I_Ks complex

Kshama D Chandrasekhar, Anatoli Lvov, Cecile Terrenoire, Grace Y Gao, Robert S Kass, William R Kobertz

J Physiol. 2011 Aug 1; 589(Pt 15): 3721–3730. Published online 2011 Jun 13. doi: 10.1113/jphysiol.2011.211284

PMCID:: PMC3171881

Abstract Article PDF–361K

Select item 316712019.

Renal defects in KCNE1 knockout mice are mimicked by chromanol 293B in vivo: identification of a KCNE1-regulated K⁺ conductance in the proximal tubule

A M Neal, H C Taylor, I D Millar, J D Kibble, S J White, L Robson

J Physiol. 2011 Jul 15; 589(Pt 14): 3595–3609. Published online 2011 May 16. doi: 10.1113/jphysiol.2011.209155

PMCID:: PMC3167120

Abstract Article PDF–673K

Select item 302253420.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

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