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Select item 113881031.

Sendai virus-mediated RNA delivery restores fertility to congenital and chemotherapy-induced infertile female mice

Mito Kanatsu-Shinohara, Hiroko Morimoto, Tianjiao Liu, Masaru Tamura, Takashi Shinohara

PNAS Nexus. 2024 Sep; 3(9): pgae375. Published online 2024 Sep 3. doi: 10.1093/pnasnexus/pgae375

PMCID:: PMC11388103

Abstract Article PDF–1.6M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108732813.

Luteinizing hormone stimulates ingression of mural granulosa cells within the mouse preovulatory follicle

Corie M Owen, Laurinda A Jaffe

Biol Reprod. 2024 Feb; 110(2): 288–299. Published online 2023 Oct 17. doi: 10.1093/biolre/ioad142

PMCID:: PMC10873281

Abstract Article PDF–2.6M

Select item 105824104.

Precise Correction of Lhcgr Mutation in Stem Leydig Cells by Prime Editing Rescues Hereditary Primary Hypogonadism in Mice

Kai Xia, Fulin Wang, Zhipeng Tan, Suyuan Zhang, Xingqiang Lai, Wangsheng Ou, Cuifeng Yang, Hong Chen, Hao Peng, Peng Luo, Anqi Hu, Xiang'an Tu, Tao Wang, Qiong Ke, Chunhua Deng, Andy Peng Xiang

Adv Sci (Weinh) 2023 Oct; 10(29): 2300993. Published online 2023 Sep 11. doi: 10.1002/advs.202300993

PMCID:: PMC10582410

Abstract Article PDF–8.9M

Select item 96043015.

The Corticosterone–Glucocorticoid Receptor–AP1/CREB Axis Inhibits the Luteinizing Hormone Receptor Expression in Mouse Granulosa Cells

Xuan Zhang, Yinghui Wei, Xiaoxuan Li, Chengyu Li, Liangliang Zhang, Zhaojun Liu, Yan Cao, Weijian Li, Xiying Zhang, Jiaqing Zhang, Ming Shen, Honglin Liu

Int J Mol Sci. 2022 Oct; 23(20): 12454. Published online 2022 Oct 18. doi: 10.3390/ijms232012454

PMCID:: PMC9604301

Abstract Article PDF–3.5M

Select item 91142976.

Downregulation of LHCGR Attenuates COX-2 Expression and Induces Luteinized Unruptured Follicle Syndrome in Endometriosis

Ting Geng, Yifan Sun, Lin Cheng, Yuming Cao, Ming Zhang, Zhidan Hong, Ling Ma, Yuanzhen Zhang

Front Endocrinol (Lausanne) 2022; 13: 853563. Published online 2022 May 4. doi: 10.3389/fendo.2022.853563

PMCID:: PMC9114297

Abstract Article PDF–7.3M

Select item 82998667.

Constitutive expression of Steroidogenic factor-1 (NR5A1) disrupts ovarian functions, fertility and metabolic homeostasis in female mice

Emmi Rotgers, Barbara Nicol, Karina Rodriguez, Saniya Rattan, Jodi A. Flaws, Humphrey Hung-Chang Yao

FASEB J. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: FASEB J. 2021 Aug; 35(8): e21770. doi: 10.1096/fj.202100304R

PMCID:: PMC8299866

Abstract Article PDF–2.6M

Select item 81711898.

The Luteinizing Hormone Receptor Knockout Mouse as a Tool to Probe the In Vivo Actions of Gonadotropic Hormones/Receptors in Females

Kim Carol Jonas, Adolfo Rivero Müller, Olayiwola Oduwole, Hellevi Peltoketo, Ilpo Huhtaniemi

Endocrinology. 2021 May; 162(5): bqab035. Published online 2021 Feb 19. doi: 10.1210/endocr/bqab035

PMCID:: PMC8171189

Abstract Article

Select item 79387709.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 768614010.

Constitutive LH receptor activity impairs NO mediated penile smooth muscle relaxation

Deepak S. Hiremath, Fernanda B.M. Priviero, R. Clinton Webb, CheMyong Ko, Prema Narayan

Reproduction. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Reproduction. 2021 Jan; 161(1): 31–41. doi: 10.1530/REP-20-0447

PMCID:: PMC7686140

Abstract Article PDF–844K

Select item 757496511.

Cellular Heterogeneity of the Luteinizing Hormone Receptor and Its Significance for Cyclic GMP Signaling in Mouse Preovulatory Follicles

Valentina Baena, Corie M Owen, Tracy F Uliasz, Katie M Lowther, Siu-Pok Yee, Mark Terasaki, Jeremy R Egbert, Laurinda A Jaffe

Endocrinology. 2020 Jul; 161(7): bqaa074. Published online 2020 May 8. doi: 10.1210/endocr/bqaa074

PMCID:: PMC7574965

Abstract Article

Select item 659746812.

Poorly-Controlled Type 1 Diabetes Mellitus Impairs LH-LHCGR Signaling in the Ovaries and Decreases Female Fertility in Mice

Jaewang Lee, Hoi Chang Lee, So-Youn Kim, Geum Joon Cho, Teresa K. Woodruff

Yonsei Med J. 2019 Jul 1; 60(7): 667–678. Published online 2019 Jun 24. doi: 10.3349/ymj.2019.60.7.667

PMCID:: PMC6597468

Abstract Article PDF–1.7M

Select item 631083413.

Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex

Mickael Mathieu, Coralie Drelon, Stéphanie Rodriguez, Houda Tabbal, Amandine Septier, Christelle Damon-Soubeyrand, Typhanie Dumontet, Annabel Berthon, Isabelle Sahut-Barnola, Cyril Djari, Marie Batisse-Lignier, Jean-Christophe Pointud, Damien Richard, Gwenneg Kerdivel, Marie-Ange Calméjane, Valentina Boeva, Igor Tauveron, Anne-Marie Lefrançois-Martinez, Antoine Martinez, Pierre Val

Proc Natl Acad Sci U S A. 2018 Dec 26; 115(52): E12265–E12274. Published online 2018 Dec 12. doi: 10.1073/pnas.1809185115

PMCID:: PMC6310834

Abstract Article PDF–2.4M

Select item 613744914.

Genetic ablation of androgen receptor signaling in fetal Leydig cell lineage affects Leydig cell functions in adult testis

Elena M. Kaftanovskaya, Carolina Lopez, Lydia Ferguson, Courtney Myhr, Alexander I. Agoulnik

FASEB J. 2015 Jun; 29(6): 2327–2337. Published online 2015 Feb 20. doi: 10.1096/fj.14-263632

PMCID:: PMC6137449

Abstract Article

Select item 607483815.

Age-dependent effects of Armc5 haploinsufficiency on adrenocortical function

A. Berthon, F.R. Faucz, S. Espiard, L. Drougat, J. Bertherat, C.A. Stratakis

Hum Mol Genet. 2017 Sep 15; 26(18): 3495–3507. Published online 2017 Jun 20. doi: 10.1093/hmg/ddx235

PMCID:: PMC6074838

Abstract Article PDF–2.2M

Select item 606331316.

Confirmation of luteinizing hormone (LH) in living human vitreous and the effect of LH receptor reduction on murine electroretinogram.

Tammy Z Movsas, Kwoon Y Wong, Michael D Ober, Robert Sigler, Zhenmin M Lei, Arivalagan Muthusamy

Neuroscience. Author manuscript; available in PMC 2019 Aug 10.

Published in final edited form as: Neuroscience. 2018 Aug 10; 385: 1–10. Published online 2018 Jun 8. doi: 10.1016/j.neuroscience.2018.05.049

PMCID:: PMC6063313

Abstract Article PDF–452K

Select item 591983117.

Constitutively active follicle-stimulating hormone receptor enables androgen-independent spermatogenesis

Olayiwola O. Oduwole, Hellevi Peltoketo, Ariel Poliandri, Laura Vengadabady, Marcin Chrusciel, Milena Doroszko, Luna Samanta, Laura Owen, Brian Keevil, Nafis A. Rahman, Ilpo T. Huhtaniemi

J Clin Invest. 2018 May 1; 128(5): 1787–1792. Published online 2018 Mar 26. doi: 10.1172/JCI96794

PMCID:: PMC5919831

Abstract Article PDF–6.0M

Select item 551306618.

Impact of RNA structure on ZFP36L2 interaction with luteinizing hormone receptor mRNA

Christopher B. Ball, Amanda C. Solem, Rita M. Meganck, Alain Laederach, Silvia B.V. Ramos

RNA. 2017 Aug; 23(8): 1209–1223. doi: 10.1261/rna.060467.116

PMCID:: PMC5513066

Abstract Article PDF–676K

Select item 541467119.

Fetal Leydig Cells Persist as an Androgen-Independent Subpopulation in the Postnatal Testis

Yuichi Shima, Sawako Matsuzaki, Kanako Miyabayashi, Hiroyuki Otake, Takashi Baba, Shigeaki Kato, Ilpo Huhtaniemi, Ken-ichirou Morohashi

Mol Endocrinol. 2015 Nov; 29(11): 1581–1593. Published online 2015 Sep 24. doi: 10.1210/me.2015-1200

PMCID:: PMC5414671

Abstract Article

Select item 513334620.

Neuregulin 1 Regulates Proliferation of Leydig Cells to Support Spermatogenesis and Sexual Behavior in Adult Mice

Takashi Umehara, Ikko Kawashima, Tomoko Kawai, Yumi Hoshino, Ken-ichirou Morohashi, Yuichi Shima, Wenxian Zeng, JoAnne S. Richards, Masayuki Shimada

Endocrinology. 2016 Dec; 157(12): 4899–4913. Published online 2016 Oct 12. doi: 10.1210/en.2016-1478

PMCID:: PMC5133346

Abstract Article

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