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Select item 113440131.

Tissue Inhibitor of Metalloproteinase 3 (TIMP3) mutations increase glycolytic activity and dysregulate glutamine metabolism in RPE cells

Allison Grenell, Charandeep Singh, Monisha Raju, Alyson Wolk, Sonal Dalvi, Geeng-Fu Jang, John S. Crabb, Courtney E. Hershberger, Kannan V. Manian, Karen Hernandez, John W. Crabb, Ruchira Singh, Jianhai Du, Bela Anand-Apte

Mol Metab. 2024 Oct; 88: 101995. Published online 2024 Jul 22. doi: 10.1016/j.molmet.2024.101995

PMCID:: PMC11344013

Abstract Article PDF–2.8M

Select item 110213422.

TIMP-3 Alleviates White Matter Injury After Subarachnoid Hemorrhage in Mice by Promoting Oligodendrocyte Precursor Cell Maturation

Peiwen Guo, Xufang Ru, Jiru Zhou, Mao Chen, Yanling Li, Mingxu Duan, Yuanshu Li, Wenyan Li, Yujie Chen, Shilun Zuo, Hua Feng

Cell Mol Neurobiol. 2024 Dec; 44: 33. Published online 2024 Apr 16. doi: 10.1007/s10571-024-01469-2

PMCID:: PMC11021342

Abstract Article PDF–7.9M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108766484.

PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development

Jong Geol Lee, Jung-Min Yon, Globinna Kim, Seul-Gi Lee, C-Yoon Kim, Seung-A Cheong, Hyun-Yi Kim, Jiyoung Yu, Kyunggon Kim, Young Hoon Sung, Hyun Ju Yoo, Dong-Cheol Woo, Jin Kyung Rho, Chang Hoon Ha, Chan-Gi Pack, Seak Hee Oh, Joon Seo Lim, Yu Mi Han, Eui-Ju Hong, Je Kyung Seong, Han-Woong Lee, Sang-Wook Lee, Ki-Up Lee, Chong Jai Kim, Sang-Yoon Nam, You Sook Cho, In-Jeoung Baek

Nat Commun. 2024; 15: 1487. Published online 2024 Feb 19. doi: 10.1038/s41467-024-45647-8

PMCID:: PMC10876648

Abstract Article PDF–10M

Select item 108353815.

TIMP3 overexpression in myeloid lineage alleviates pancreatic damage and confers resistance to the development of type 1 diabetes in the MLDS -induced model

Viviana Casagrande, Stefano Menini, Chiara Internò, Giuseppe Pugliese, Massimo Federici, Rossella Menghini

Front Endocrinol (Lausanne) 2023; 14: 1297847. Published online 2024 Jan 19. doi: 10.3389/fendo.2023.1297847

PMCID:: PMC10835381

Abstract Article PDF–4.7M

Select item 105266396.

The Histone Methyltransferase Setdb2 Modulates TIMP-MMP Activity During Abdominal Aortic Aneurysm Development

Frank M. Davis, William J. Melvin, Kevin Mangum, Lam C. Tsoi, Amrita D. Joshi, Qing Cai, Peter K. Henke, Johann E. Gudjonsson, Katherine A. Gallagher

Ann Surg. Author manuscript; available in PMC 2024 Sep 1.

Published in final edited form as: Ann Surg. 2023 Sep 1; 278(3): 426–440. Published online 2023 Jun 16. doi: 10.1097/SLA.0000000000005963

PMCID:: PMC10526639

Abstract Article PDF–1.9M

Select item 103388477.

TIMP3 promotes the maintenance of neural stem-progenitor cells in the mouse subventricular zone

Lingyan Fang, Takaaki Kuniya, Yujin Harada, Osamu Yasuda, Nobuyo Maeda, Yutaka Suzuki, Daichi Kawaguchi, Yukiko Gotoh

Front Neurosci. 2023; 17: 1149603. Published online 2023 Jun 28. doi: 10.3389/fnins.2023.1149603

PMCID:: PMC10338847

Abstract Article PDF–21M

Select item 94819758.

Understanding the development of oral epithelial organs through single cell transcriptomic analysis

Qianlin Ye, Arshia Bhojwani, Jimmy K. Hu

Development. 2022 Aug 15; 149(16): dev200539. Published online 2022 Aug 17. doi: 10.1242/dev.200539

PMCID:: PMC9481975

Abstract Article

Select item 83132399.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 798246110.

Generation of Transgenic Mice that Conditionally Overexpress Tenascin-C

Saori Yonebayashi, Kazuko Tajiri, Mari Hara, Hiromitsu Saito, Noboru Suzuki, Satoshi Sakai, Taizo Kimura, Akira Sato, Akiyo Sekimoto, Satoshi Fujita, Ryuji Okamoto, Robert J. Schwartz, Toshimichi Yoshida, Kyoko Imanaka-Yoshida

Front Immunol. 2021; 12: 620541. Published online 2021 Mar 8. doi: 10.3389/fimmu.2021.620541

PMCID:: PMC7982461

Abstract Article PDF–2.5M

Select item 776775311.

The retinal pigment epithelium in Sorsby Fundus Dystrophy shows increased sensitivity to oxidative stress-induced degeneration

Alyson Wolk, Mala Upadhyay, Mariya Ali, Jason Suh, Heidi Stoehr, Vera L. Bonilha, Bela Anand-Apte

Redox Biol. 2020 Oct; 37: 101681. Published online 2020 Aug 10. doi: 10.1016/j.redox.2020.101681

PMCID:: PMC7767753

Abstract Article PDF–5.6M

Select item 766312312.

Targeted Disruption of Mouse Dip2B Leads to Abnormal Lung Development and Prenatal Lethality

Rajiv Kumar Sah, Jun Ma, Fatoumata Binta Bah, Zhenkai Xing, Salah Adlat, Zin Ma Oo, Yajun Wang, Noor Bahadar, Ameer Ali Bohio, Farooq Hayel Nagi, Xuechao Feng, Luqing Zhang, Yaowu Zheng

Int J Mol Sci. 2020 Nov; 21(21): 8223. Published online 2020 Nov 3. doi: 10.3390/ijms21218223

PMCID:: PMC7663123

Abstract Article PDF–4.7M

Select item 750012413.

Overexpression of Linc 4930556M19Rik Suppresses High Glucose-Triggered Podocyte Apoptosis, Fibrosis and Inflammation via the miR-27a-3p/Metalloproteinase 3 (TIMP3) Axis in Diabetic Nephropathy

Hong Fan, Weiwei Zhang

Med Sci Monit. 2020; 26: e925361-1–e925361-11. Prepublished online 2020 Jul 10. Published online 2020 Sep 8. doi: 10.12659/MSM.925361

PMCID:: PMC7500124

Abstract Article PDF–784K

Select item 728327414.

Aggrecanase-selective tissue inhibitor of metalloproteinase-3 (TIMP3) protects articular cartilage in a surgical mouse model of osteoarthritis

Hiroyuki Nakamura, Phoung Vo, Ioannis Kanakis, Ke Liu, George Bou-Gharios

Sci Rep. 2020; 10: 9288. Published online 2020 Jun 9. doi: 10.1038/s41598-020-66233-0

PMCID:: PMC7283274

Abstract Article PDF–4.9M

Select item 718936415.

MiR-770-5p facilitates podocyte apoptosis and inflammation in diabetic nephropathy by targeting TIMP3

Li Wang, Hua Li

Biosci Rep. 2020 Apr 30; 40(4): BSR20193653. Published online 2020 Apr 29. doi: 10.1042/BSR20193653

PMCID:: PMC7189364

Abstract Article PDF–1.3M

Select item 671945916.

Metalloprotease inhibitor TIMP proteins control FGF-2 bioavailability and regulate skeletal growth

Sanjay Saw, Alison Aiken, Hui Fang, Trevor D. McKee, Sarah Bregant, Otto Sanchez, Yan Chen, Ashley Weiss, Brendan C. Dickson, Bertrand Czarny, Ankit Sinha, Amanda Fosang, Vincent Dive, Paul D. Waterhouse, Thomas Kislinger, Rama Khokha

J Cell Biol. 2019 Sep 2; 218(9): 3134–3152. Published online 2019 Aug 1. doi: 10.1083/jcb.201906059

PMCID:: PMC6719459

Abstract Article PDF–5.8M

Select item 639846917.

The Forkhead box F1 transcription factor inhibits collagen deposition and accumulation of myofibroblasts during liver fibrosis

Hannah M. Flood, Craig Bolte, Nupur Dasgupta, Akanksha Sharma, Yufang Zhang, Chandrashekhar R. Gandhi, Tanya V. Kalin, Vladimir V. Kalinichenko

Biol Open. 2019 Feb 15; 8(2): bio039800. Published online 2019 Jan 23. doi: 10.1242/bio.039800

PMCID:: PMC6398469

Abstract Article PDF–9.6M

Select item 634014818.

Transcriptionally dynamic progenitor populations organised around a stable niche drive axial patterning

Filip J. Wymeersch, Stavroula Skylaki, Yali Huang, Julia A. Watson, Constantinos Economou, Carylyn Marek-Johnston, Simon R. Tomlinson, Valerie Wilson

Development. 2019 Jan 1; 146(1): dev168161. Published online 2019 Jan 2. doi: 10.1242/dev.168161

PMCID:: PMC6340148

Abstract Article

Select item 632107819.

The Activity of Matrix Metalloproteinases (MMP-2, MMP-9) and Their Tissue Inhibitors (TIMP-1, TIMP-3) in the Cerebral Cortex and Hippocampus in Experimental Acanthamoebiasis

Natalia Łanocha-Arendarczyk, Irena Baranowska-Bosiacka, Izabela Gutowska, Agnieszka Kolasa-Wołosiuk, Karolina Kot, Aleksandra Łanocha, Emilia Metryka, Barbara Wiszniewska, Dariusz Chlubek, Danuta Kosik-Bogacka

Int J Mol Sci. 2018 Dec; 19(12): 4128. Published online 2018 Dec 19. doi: 10.3390/ijms19124128

PMCID:: PMC6321078

Abstract Article PDF–4.6M

Select item 600815220.

TIMP3 deficiency exacerbates iron overload-mediated cardiomyopathy and liver disease

Pavel Zhabyeyev, Subhash K. Das, Ratnadeep Basu, Mengcheng Shen, Vaibhav B. Patel, Zamaneh Kassiri, Gavin Y. Oudit

Am J Physiol Heart Circ Physiol. 2018 May 1; 314(5): H978–H990. Published online 2018 Jan 26. doi: 10.1152/ajpheart.00597.2017

PMCID:: PMC6008152

Abstract Article

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