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Select item 111788421.

Loss of connectin novex-3 leads to heart dysfunction associated with impaired cardiomyocyte proliferation and abnormal nuclear mechanics

Ken Hashimoto, Momoko Ohira, Aya Kodama, Misaki Kimoto, Mariko Inoue, Shigenobu Toné, Yuu Usui, Akira Hanashima, Takato Goto, Yuhei Ogura, Yoshihiro Ujihara, Satoshi Mohri

Sci Rep. 2024; 14: 13727. Published online 2024 Jun 14. doi: 10.1038/s41598-024-64608-1

PMCID:: PMC11178842

Abstract Article PDF–5.4M

Select item 109535652.

Cfp1 Controls Cardiomyocyte Maturation by Modifying Histone H3K4me3 of Structural, Metabolic, and Contractile Related Genes

Changzhu Li, Yang Zhang, Jingling Shen, Hairong Bao, Yue Zhao, Desheng Li, Sijia Li, Yining Liu, Jiming Yang, Zhiwen Zhou, Kangyi Gao, Lexin Zhao, Yao Pei, Yanjie Lu, Zhenwei Pan, Benzhi Cai

Adv Sci (Weinh) 2024 Mar; 11(11): 2305992. Published online 2024 Jan 9. doi: 10.1002/advs.202305992

PMCID:: PMC10953565

Abstract Article PDF–5.8M

Select item 106520393.

The transcription factor EBF1 non-cell-autonomously regulates cardiac growth and differentiation

Eugene E. Kim, Akshay Shekhar, Jayalakshmi Ramachandran, Alireza Khodadadi-Jamayran, Fang-Yu Liu, Jie Zhang, Glenn I. Fishman

Development. 2023 Nov 1; 150(21): dev202054. Published online 2023 Oct 24. doi: 10.1242/dev.202054

PMCID:: PMC10652039

Abstract Article

Select item 104787534.

Lem2 is essential for cardiac development by maintaining nuclear integrity

Jacob A Ross, Nathaly Arcos-Villacis, Edmund Battey, Cornelis Boogerd, Constanza Avalos Orellana, Emilie Marhuenda, Pamela Swiatlowska, Didier Hodzic, Fabrice Prin, Tim Mohun, Norman Catibog, Olga Tapia, Larry Gerace, Thomas Iskratsch, Ajay M Shah, Matthew J Stroud

Cardiovasc Res. 2023 Aug; 119(11): 2074–2088. Published online 2023 Apr 17. doi: 10.1093/cvr/cvad061

PMCID:: PMC10478753

Abstract Article PDF–33M

Select item 104042865.

Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation

Cornelis J. Boogerd, Ilaria Perini, Eirini Kyriakopoulou, Su Ji Han, Phit La, Britt van der Swaan, Jari B. Berkhout, Danielle Versteeg, Jantine Monshouwer-Kloots, Eva van Rooij

Nat Commun. 2023; 14: 4716. Published online 2023 Aug 5. doi: 10.1038/s41467-023-40203-2

PMCID:: PMC10404286

Abstract Article PDF–3.4M

Select item 103303626.

Polycomb group protein CBX7 represses cardiomyocyte proliferation via modulation of the TARDBP/RBM38 axis

Kyu-Won Cho, Mark Andrade, Seongho Bae, Sangsung Kim, Jin Eyun Kim, Er Yearn Jang, Sangho Lee, Ahsan Husain, Roy L. Sutliff, John W. Calvert, Changwon Park, Young-sup Yoon

Circulation. Author manuscript; available in PMC 2024 Jun 13.

Published in final edited form as: Circulation. 2023 Jun 13; 147(24): 1823–1842. Published online 2023 May 9. doi: 10.1161/CIRCULATIONAHA.122.061131

PMCID:: PMC10330362

Abstract Article PDF–1.6M

Select item 102808537.

Induction of filopodia formation by α-Actinin-2 via RelA with a feedforward activation loop promoting overt bone marrow metastasis of gastric cancer

Caiqin Wang, Bo Xie, Shi Yin, Jianghua Cao, Junhao Huang, Longyang Jin, Ge Du, Xiaohui Zhai, Rongqin Zhang, Shanshan Li, Taiyuan Cao, Hongen Yu, Xinjuan Fan, Zuli Yang, Junsheng Peng, Jian Xiao, Lei Lian

J Transl Med. 2023; 21: 399. Published online 2023 Jun 19. doi: 10.1186/s12967-023-04156-w

PMCID:: PMC10280853

Abstract Article PDF–3.3M

Select item 101487278.

ETS1 loss in mice impairs cardiac outflow tract septation via a cell migration defect autonomous to the neural crest

Lizhu Lin, Antonella Pinto, Lu Wang, Kazumi Fukatsu, Yan Yin, Simon D Bamforth, Marianne E Bronner, Sylvia M Evans, Shuyi Nie, Robert H Anderson, Alexey V Terskikh, Paul D Grossfeld

Hum Mol Genet. 2022 Dec 15; 31(24): 4217–4227. Published online 2022 Jul 28. doi: 10.1093/hmg/ddac174

PMCID:: PMC10148727

Abstract Article PDF–2.2M

Select item 100013729.

Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2

Sophie Broadway-Stringer, He Jiang, Kirsty Wadmore, Charlotte Hooper, Gillian Douglas, Violetta Steeples, Amar J. Azad, Evie Singer, Jasmeet S. Reyat, Frantisek Galatik, Elisabeth Ehler, Pauline Bennett, Jacinta I. Kalisch-Smith, Duncan B. Sparrow, Benjamin Davies, Kristina Djinovic-Carugo, Mathias Gautel, Hugh Watkins, Katja Gehmlich

Cells. 2023 Mar; 12(5): 721. Published online 2023 Feb 24. doi: 10.3390/cells12050721

PMCID:: PMC10001372

Abstract Article PDF–2.7M

Select item 990782710.

Filamin C is Essential for mammalian myocardial integrity

Tongbin Wu, Yujun Xu, Lunfeng Zhang, Zhengyu Liang, Xiaohai Zhou, Sylvia M. Evans, Ju Chen

PLoS Genet. 2023 Jan; 19(1): e1010630. Published online 2023 Jan 27. doi: 10.1371/journal.pgen.1010630

PMCID:: PMC9907827

Abstract Article PDF–3.3M

Select item 971882311.

DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal

Paola Cattaneo, Michael G. B. Hayes, Nina Baumgarten, Dennis Hecker, Sofia Peruzzo, Galip S. Aslan, Paolo Kunderfranco, Veronica Larcher, Lunfeng Zhang, Riccardo Contu, Gregory Fonseca, Simone Spinozzi, Ju Chen, Gianluigi Condorelli, Stefanie Dimmeler, Marcel H. Schulz, Sven Heinz, Nuno Guimarães-Camboa, Sylvia M. Evans

Nat Commun. 2022; 13: 7444. Published online 2022 Dec 2. doi: 10.1038/s41467-022-35070-2

PMCID:: PMC9718823

Abstract Article PDF–9.4M

Select item 901661912.

SIRT1 regulates cardiomyocyte alignment during maturation

Yi Fang, Wei Fan, Xiaojiang Xu, Agnes K. Janoshazi, David C. Fargo, Xiaoling Li

J Cell Sci. 2022 Apr 1; 135(7): jcs259076. Published online 2022 Apr 1. doi: 10.1242/jcs.259076

PMCID:: PMC9016619

Abstract Article

Select item 898408213.

Growth arrest of PPP2R5C and PPP2R5D double knockout mice indicates a genetic interaction and conserved function for these PP2A B subunits

Jade J. Dyson, Fatima Abbasi, Prajakta Varadkar, Brent McCright

FASEB Bioadv. 2022 Apr; 4(4): 273–282. Published online 2021 Dec 28. doi: 10.1096/fba.2021-00130

PMCID:: PMC8984082

Abstract Article PDF–1.8M

Select item 885469414.

ASPP2 maintains the integrity of mechanically stressed pseudostratified epithelia during morphogenesis

Christophe Royer, Elizabeth Sandham, Elizabeth Slee, Falk Schneider, Christoffer B. Lagerholm, Jonathan Godwin, Nisha Veits, Holly Hathrell, Felix Zhou, Karolis Leonavicius, Jemma Garratt, Tanaya Narendra, Anna Vincent, Celine Jones, Tim Child, Kevin Coward, Chris Graham, Marco Fritzsche, Xin Lu, Shankar Srinivas

Nat Commun. 2022; 13: 941. Published online 2022 Feb 17. doi: 10.1038/s41467-022-28590-4

PMCID:: PMC8854694

Abstract Article PDF–15M

Select item 871060515.

Phosphoproteomic Analysis Reveals Downstream PKA Effectors of AKAP Cypher/ZASP in the Pathogenesis of Dilated Cardiomyopathy

Jialan Lv, Zhicheng Pan, Jian Chen, Rui Xu, Dongfei Wang, Jiaqi Huang, Yang Dong, Jing Jiang, Xiang Yin, Hongqiang Cheng, Xiaogang Guo

Front Cardiovasc Med. 2021; 8: 753072. Published online 2021 Dec 13. doi: 10.3389/fcvm.2021.753072

PMCID:: PMC8710605

Abstract Article PDF–5.2M

Select item 849615516.

Deletion of Sphingosine 1‐Phosphate receptor 1 in cardiomyocytes during development leads to abnormal ventricular conduction and fibrosis

Ryan Jorgensen, Meghna Katta, Jayne Wolfe, Desiree F. Leach, Bianca Lavelle, Jerold Chun, Lisa D. Wilsbacher

Physiol Rep. 2021 Oct; 9(19): e15060. Published online 2021 Oct 7. doi: 10.14814/phy2.15060

PMCID:: PMC8496155

Abstract Article PDF–2.8M

Select item 820042317.

Autoantibody of NRIP, a novel AChR‐interacting protein, plays a detrimental role in myasthenia gravis

Li‐Kai Tsai, I‐Hsin Chen, Chi‐Chao Chao, Hsueh‐Wen Hsueh, Hsin‐Hsiung Chen, Yun‐Hsin Huang, Rong‐Wei Weng, Tzu‐Yun Lai, Yi‐Chieh Tsai, Yeou‐Ping Tsao, Show‐Li Chen

J Cachexia Sarcopenia Muscle. 2021 Jun; 12(3): 665–676. Published online 2021 Mar 26. doi: 10.1002/jcsm.12697

PMCID:: PMC8200423

Abstract Article PDF–11M

Select item 797977618.

Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCα and TSC2-mTOR downregulation

Pankaj Pathak, Yotam Blech-Hermoni, Kalpana Subedi, Jessica Mpamugo, Charissa Obeng-Nyarko, Rachel Ohman, Ilda Molloy, Malcolm Kates, Jessica Hale, Stacey Stauffer, Shyam K. Sharan, Ami Mankodi

Commun Biol. 2021; 4: 355. Published online 2021 Mar 19. doi: 10.1038/s42003-021-01864-1

PMCID:: PMC7979776

Abstract Article PDF–5.3M

Select item 793877019.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 781283220.

Sarcomeres regulate murine cardiomyocyte maturation through MRTF-SRF signaling

Yuxuan Guo, Yangpo Cao, Blake D. Jardin, Isha Sethi, Qing Ma, Behzad Moghadaszadeh, Emily C. Troiano, Neil Mazumdar, Michael A. Trembley, Eric M. Small, Guo-Cheng Yuan, Alan H. Beggs, William T. Pu

Proc Natl Acad Sci U S A. 2021 Jan 12; 118(2): e2008861118. Published online 2020 Dec 23. doi: 10.1073/pnas.2008861118

PMCID:: PMC7812832

Abstract Article PDF–4.3M

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