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Items: 1 to 20 of 55

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
3.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
4.
p38 Mitogen-activated protein kinase regulates chamber-specific perinatal growth in heart
Tomohiro Yokota, Jin Li, Jijun Huang, Zhaojun Xiong, Qing Zhang, Tracey Chan, Yichen Ding, Christoph Rau, Kevin Sung, Shuxun Ren, Rajan Kulkarni, Tzung Hsiai, Xinshu Xiao, Marlin Touma, Susumu Minamisawa, Yibin Wang
J Clin Invest. 2020 Oct 1; 130(10): 5287–5301. Published online 2020 Aug 31. doi: 10.1172/JCI135859
PMCID:
PMC7524480
AbstractArticlePDF–15M
5.
RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1
Md Rakibul Hasan, Maarit Takatalo, Hongqiang Ma, Ritva Rice, Tuija Mustonen, David PC Rice
eLife. 2020; 9: e55829. Published online 2020 Jul 14. doi: 10.7554/eLife.55829
PMCID:
PMC7423339
AbstractArticlePDF–5.4M
6.
The protein tyrosine kinase SYK regulates the alternative p38 activation in liver during acute liver inflammation
Bo-Ram Bang, Kyung Ho Han, Goo-Young Seo, Michael Croft, Young Jun Kang
Sci Rep. 2019; 9: 17838. Published online 2019 Nov 28. doi: 10.1038/s41598-019-54335-3
PMCID:
PMC6882802
AbstractArticlePDF–2.9M
7.
p38α and p38β Mitogen-Activated Protein Kinases Determine Cholinergic Transdifferentiation of Sympathetic Neurons
Bernhard Loy, Galina Apostolova, Roland Dorn, Victoria A. McGuire, J. Simon C. Arthur, Georg Dechant
J Neurosci. 2011 Aug 24; 31(34): 12059–12067. doi: 10.1523/JNEUROSCI.0448-11.2011
PMCID:
PMC6623226
AbstractArticlePDF–1.6M
8.
Astrocytic p38α MAPK drives NMDA receptor-dependent long-term depression and modulates long-term memory
Marta Navarrete, María I. Cuartero, Rocío Palenzuela, Jonathan E. Draffin, Ainoa Konomi, Irene Serra, Sandra Colié, Sergio Castaño-Castaño, Mazahir T. Hasan, Ángel R. Nebreda, José A. Esteban
Nat Commun. 2019; 10: 2968. Published online 2019 Jul 4. doi: 10.1038/s41467-019-10830-9
PMCID:
PMC6609681
AbstractArticlePDF–5.1M
9.
Unique properties of TCR-activated p38 are necessary for NFAT-dependent T-cell activation
Muhammad S. Alam, Matthias M. Gaida, Subrata Debnath, Harichandra D. Tagad, Lisa M. Miller Jenkins, Ettore Appella, M. Jubayer Rahman, Jonathan D. Ashwell
PLoS Biol. 2018 Jan; 16(1): e2004111. Published online 2018 Jan 22. doi: 10.1371/journal.pbio.2004111
PMCID:
PMC5794172
AbstractArticlePDF–6.6M
10.
Peripheral deletion of CD8 T cells requires p38 mitogen activated protein kinase in cross-presenting dendritic cells
Trevor Smith, Xiaotian Lin, Marielle Mello, Kristi Marquardt, Jocelyn Cheung, Binfeng Lu, Linda A Sherman, Grégory Verdeil
J Immunol. Author manuscript; available in PMC 2018 Oct 15.
Published in final edited form as: J Immunol. 2017 Oct 15; 199(8): 2713–2720. Published online 2017 Sep 1. doi: 10.4049/jimmunol.1700427
PMCID:
PMC5679299
AbstractArticlePDF–2.5M
11.
Activin A induces skeletal muscle catabolism via p38β mitogen‐activated protein kinase
Hui Ding, Guohua Zhang, Ka Wai Thomas Sin, Zhelong Liu, Ren‐Kuo Lin, Min Li, Yi‐Ping Li
J Cachexia Sarcopenia Muscle. 2017 Apr; 8(2): 202–212. Published online 2016 Sep 16. doi: 10.1002/jcsm.12145
PMCID:
PMC5377410
AbstractArticlePDF–828K
12.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
13.
Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction
Morisada Hayakawa, Hiroko Hayakawa, Tsvetana Petrova, Patcharee Ritprajak, Ruhcha V. Sutavani, Guillermina Yanek Jiménez-Andrade, Yasuyo Sano, Min-Kyung Choo, John Seavitt, Ram K. C. Venigalla, Kinya Otsu, Katia Georgopoulos, J. Simon C. Arthur, Jin Mo Park
J Biol Chem. 2017 Feb 3; 292(5): 1762–1772. Published online 2016 Dec 23. doi: 10.1074/jbc.M116.764548
PMCID:
PMC5290950
AbstractArticlePDF–3.5M
14.
p38 (Mapk14/11) occupies a regulatory node governing entry into primitive endoderm differentiation during preimplantation mouse embryo development
Vasanth Thamodaran, Alexander W. Bruce
Open Biol. 2016 Sep; 6(9): 160190. Published online 2016 Sep 7. doi: 10.1098/rsob.160190
PMCID:
PMC5043583
AbstractArticlePDF–1.4M
15.
p38β Mitogen-Activated Protein Kinase Modulates Its Own Basal Activity by Autophosphorylation of the Activating Residue Thr180 and the Inhibitory Residues Thr241 and Ser261
Jonah Beenstock, Dganit Melamed, Navit Mooshayef, Dafna Mordechay, Benjamin P. Garfinkel, Natalie G. Ahn, Arie Admon, David Engelberg
Mol Cell Biol. 2016 May 15; 36(10): 1540–1554. Prepublished online 2016 Mar 14. Published online 2016 May 2. doi: 10.1128/MCB.01105-15
PMCID:
PMC4859693
AbstractArticlePDF–2.9M
16.
Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression
Muhammad S. Alam, Matthias M. Gaida, Frank Bergmann, Felix Lasitschka, Thomas Giese, Nathalia A. Giese, Thilo Hackert, Ulf Hinz, S. Perwez Hussain, Serguei V. Kozlov, Jonathan D. Ashwell
Nat Med. Author manuscript; available in PMC 2016 May 1.
Published in final edited form as: Nat Med. 2015 Nov; 21(11): 1337–1343. Published online 2015 Oct 19. doi: 10.1038/nm.3957
PMCID:
PMC4636461
AbstractArticlePDF–803K
17.
P38 MAPK signaling underlies a cell autonomous loss of stem cell self-renewal in aged skeletal muscle
Jennifer D. Bernet, Jason D. Doles, John K. Hall, Kathleen Kelly-Tanaka, Thomas A. Carter, Bradley B. Olwin
Nat Med. Author manuscript; available in PMC 2014 Sep 1.
Published in final edited form as: Nat Med. 2014 Mar; 20(3): 265–271. Published online 2014 Feb 16. doi: 10.1038/nm.3465
PMCID:
PMC4070883
AbstractArticlePDF–2.8M
18.
Counter-regulation of T cell effector function by differentially activated p38
Muhammad S. Alam, Matthias M. Gaida, Youichi Ogawa, Antonios G.A. Kolios, Felix Lasitschka, Jonathan D. Ashwell
J Exp Med. 2014 Jun 2; 211(6): 1257–1270. doi: 10.1084/jem.20131917
PMCID:
PMC4042639
AbstractArticlePDF–2.5M
19.
TGFß2 dictates disseminated tumour cell fate in target organs through TGFß-RIII and p38a/ß signalling
Paloma Bragado, Yeriel Estrada, Falguni Parikh, Sarah Krause, Carla Capobianco, Hernan G. Farina, Denis M Schewe, Julio A. Aguirre-Ghiso
Nat Cell Biol. Author manuscript; available in PMC 2014 May 1.
Published in final edited form as: Nat Cell Biol. 2013 Nov; 15(11): 1351–1361. Published online 2013 Oct 27. doi: 10.1038/ncb2861
PMCID:
PMC4006312
AbstractArticlePDF–2.8M
20.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M

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