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Items: 1 to 20 of 34

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Beclin1- and Atg13-dependent autophagy activation and morroniside have synergistic effect on osteoblastogenesis
Xi Li, Yunrong Zhu, Xiangquan Lin, Chuanyuan Chen, Hui Liu, Yi Shi
Exp Biol Med (Maywood) 2022 Oct; 247(19): 1764–1775. Published online 2022 Aug 11. doi: 10.1177/15353702221116879
PMCID:
PMC9638960
AbstractArticlePDF–2.8M
3.
TRIM27 cooperates with STK38L to inhibit ULK1‐mediated autophagy and promote tumorigenesis
Yi Yang, Yifu Zhu, Shuai Zhou, Peipei Tang, Ran Xu, Yuwei Zhang, Dongping Wei, Jian Wen, Rick F Thorne, Xu Dong Zhang, Jun‐Lin Guan, Lianxin Liu, Mian Wu, Song Chen
EMBO J. 2022 Jul; 41(14): e109777. Published online 2022 Jun 7. doi: 10.15252/embj.2021109777
PMCID:
PMC9289709
AbstractArticlePDF–2.3M
4.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
5.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
6.
Ethanol-Responsive Brain Region Expression Networks: Implications for Behavioral Responses to Acute Ethanol in DBA/2J versus C57BL/6J Mice
Robnet T. Kerns, Ajay Ravindranathan, Sajida Hassan, Mary P. Cage, Tim York, James M. Sikela, Robert W. Williams, Michael F. Miles
J Neurosci. 2005 Mar 2; 25(9): 2255–2266. doi: 10.1523/JNEUROSCI.4372-04.2005
PMCID:
PMC6726093
AbstractArticlePDF–620K
7.
WDFY4 is required for cross-presentation in response to viral and tumor antigens
Derek J. Theisen, Jesse T. Davidson, IV, Carlos G. Briseño, Marco Gargaro, Elvin J. Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R. Brickner, Wandy L. Beatty, Herbert W. Virgin, William E. Gillanders, Nima Mosammaparast, Michael S. Diamond, L. David Sibley, Wayne Yokoyama, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy
Science. Author manuscript; available in PMC 2019 Jul 24.
Published in final edited form as: Science. 2018 Nov 9; 362(6415): 694–699. doi: 10.1126/science.aat5030
PMCID:
PMC6655551
AbstractArticlePDF–1020K
8.
Systematic analysis of ATG13 domain requirements for autophagy induction
Nora Wallot-Hieke, Neha Verma, David Schlütermann, Niklas Berleth, Jana Deitersen, Philip Böhler, Fabian Stuhldreier, Wenxian Wu, Sabine Seggewiß, Christoph Peter, Holger Gohlke, Noboru Mizushima, Björn Stork
Autophagy. 2018; 14(5): 743–763. Published online 2018 Mar 21. doi: 10.1080/15548627.2017.1387342
PMCID:
PMC6070014
AbstractArticlePDF–2.7M
9.
The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway
Bo Wang, Rekha Iyengar, Xiujie Li-Harms, Joung Hyuck Joo, Christopher Wright, Alfonso Lavado, Linda Horner, Mao Yang, Jun-Lin Guan, Sharon Frase, Douglas R. Green, Xinwei Cao, Mondira Kundu
Autophagy. 2018; 14(5): 796–811. Published online 2017 Dec 24. doi: 10.1080/15548627.2017.1386820
PMCID:
PMC6070005
AbstractArticlePDF–2.7M
10.
Histamine deficiency aggravates cardiac injury through miR-206/216b-Atg13 axis-mediated autophagic-dependant apoptosis
Suling Ding, Mieradilijiang Abudupataer, Zheliang Zhou, Jinmiao Chen, Hui Li, Lili Xu, Weiwei Zhang, Shuning Zhang, Yunzeng Zou, Tao Hong, Timothy C. Wang, Xiangdong Yang, Junbo Ge
Cell Death Dis. 2018 Jun; 9(6): 694. Published online 2018 Jun 7. doi: 10.1038/s41419-018-0723-6
PMCID:
PMC5992227
AbstractArticlePDF–3.2M
11.
Suppression of autophagy impedes glioblastoma development and induces senescence
Noor Gammoh, Jane Fraser, Cindy Puente, Heather M. Syred, Helen Kang, Tatsuya Ozawa, Du Lam, Juan Carlos Acosta, Andrew J. Finch, Eric Holland, Xuejun Jiang
Autophagy. 2016; 12(9): 1431–1439. Published online 2016 Jun 15. doi: 10.1080/15548627.2016.1190053
PMCID:
PMC5082770
AbstractArticlePDF–927K
12.
Nutrient-regulated Phosphorylation of ATG13 Inhibits Starvation-induced Autophagy
Cindy Puente, Ronald C. Hendrickson, Xuejun Jiang
J Biol Chem. 2016 Mar 11; 291(11): 6026–6035. Published online 2016 Jan 22. doi: 10.1074/jbc.M115.689646
PMCID:
PMC4786734
AbstractArticlePDF–2.7M
13.
Atg13 Is Essential for Autophagy and Cardiac Development in Mice
Takeshi Kaizuka, Noboru Mizushima
Mol Cell Biol. 2016 Feb 15; 36(4): 585–595. Prepublished online 2015 Dec 7. Published online 2016 Feb 1. doi: 10.1128/MCB.01005-15
PMCID:
PMC4751695
AbstractArticlePDF–4.4M
14.
Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells
Nora Hieke, Antje S Löffler, Takeshi Kaizuka, Niklas Berleth, Philip Böhler, Stefan Drießen, Fabian Stuhldreier, Olena Friesen, Kaivon Assani, Katharina Schmitz, Christoph Peter, Britta Diedrich, Jörn Dengjel, Petter Holland, Anne Simonsen, Sebastian Wesselborg, Noboru Mizushima, Björn Stork
Autophagy. 2015 Sep; 11(9): 1471–1483. Published online 2015 Jul 25. doi: 10.1080/15548627.2015.1068488
PMCID:
PMC4590663
AbstractArticlePDF–1.0M
15.
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan
Nat Cell Biol. Author manuscript; available in PMC 2014 Apr 15.
Published in final edited form as: Nat Cell Biol. 2011 Feb; 13(2): 132–141. Published online 2011 Jan 23. doi: 10.1038/ncb2152
PMCID:
PMC3987946
AbstractArticlePDF–2.3M
16.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
17.
FIP200 regulates targeting of Atg16L1 to the isolation membrane
Taki Nishimura, Takeshi Kaizuka, Ken Cadwell, Mayurbhai H Sahani, Tatsuya Saitoh, Shizuo Akira, Herbert W Virgin, Noboru Mizushima
EMBO Rep. 2013 Mar; 14(3): 284–291. Published online 2013 Feb 8. doi: 10.1038/embor.2013.6
PMCID:
PMC3589088
AbstractArticlePDF–1.1M
18.
Hsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagy
Joung Hyuck Joo, Frank C. Dorsey, Aashish Joshi, Kristin M. Hennessy-Walters, Kristie L. Rose, Kelly McCastlain, Ji Zhang, Rekha Iyengar, Chang-Hwa Jung, Der-Fen Suen, Meredith A. Steeves, Chia-Ying Yang, Stephanie M. Prater, Do-Hyung Kim, Craig B. Thompson, Richard Youle, Paul A. Ney, John L. Cleveland, Mondira Kundu
Mol Cell. Author manuscript; available in PMC 2012 Nov 1.
Published in final edited form as: Mol Cell. 2011 Aug 19; 43(4): 572–585. doi: 10.1016/j.molcel.2011.06.018
PMCID:
PMC3485687
AbstractArticlePDF–4.5M
19.
ULK1 inhibits the kinase activity of mTORC1 and cell proliferation
Chang Hwa Jung, Minchul Seo, Neil Michael Otto, Do-Hyung Kim
Autophagy. 2011 Oct; 7(10): 1212–1221. Published online 2011 Oct 1. doi: 10.4161/auto.7.10.16660
PMCID:
PMC3210307
AbstractArticlePDF–1.9M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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