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Select item 85367891.

Fatty Acids Inhibit LAMP2-Mediated Autophagy Flux via Activating ER Stress Pathway in Alcohol-Related Liver Disease

Wei Guo, Wei Zhong, Liuyi Hao, Haibo Dong, Xinguo Sun, Ruichao Yue, Tianjiao Li, Zhanxiang Zhou

Cell Mol Gastroenterol Hepatol. 2021; 12(5): 1599–1615. Published online 2021 Jul 17. doi: 10.1016/j.jcmgh.2021.07.002

PMCID:: PMC8536789

Abstract Article PDF–6.3M

Select item 78812682.

Hypoxia-inducible lipid droplet-associated induces DGAT1 and promotes lipid storage in hepatocytes

Montserrat A. de la Rosa Rodriguez, Lei Deng, Anne Gemmink, Michel van Weeghel, Marie Louise Aoun, Christina Warnecke, Rajat Singh, Jan Willem Borst, Sander Kersten

Mol Metab. 2021 May; 47: 101168. Published online 2021 Jan 16. doi: 10.1016/j.molmet.2021.101168

PMCID:: PMC7881268

Abstract Article PDF–4.4M

Select item 78435143.

Hepatic synthesis of triacylglycerols containing medium-chain fatty acids is dominated by diacylglycerol acyltransferase 1 and efficiently inhibited by etomoxir

Klaus Wunderling, Christina Leopold, Isabell Jamitzky, Mohamed Yaghmour, Fabian Zink, Dagmar Kratky, Christoph Thiele

Mol Metab. 2021 Mar; 45: 101150. Published online 2020 Dec 23. doi: 10.1016/j.molmet.2020.101150

PMCID:: PMC7843514

Abstract Article PDF–3.1M

Select item 76966564.

Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis

Chandramohan Chitraju, Alexander W. Fischer, Robert V. Farese, Jr., Tobias C. Walther

Cell Rep. Author manuscript; available in PMC 2020 Nov 28.

Published in final edited form as: Cell Rep. 2020 Nov 3; 33(5): 108348. doi: 10.1016/j.celrep.2020.108348

PMCID:: PMC7696656

Abstract Article PDF–1.6M

Select item 74159915.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 71162656.

Intestine-specific DGAT1 deficiency improves atherosclerosis in apolipoprotein E knockout mice by reducing systemic cholesterol burden

Nemanja Vujić, Melanie Korbelius, Vinay Sachdev, Silvia Rainer, Andreas Zimmer, Anton Huber, Branislav Radović, Dagmar Kratky

Atherosclerosis. Author manuscript; available in PMC 2020 Oct 27.

Published in final edited form as: Atherosclerosis. 2020 Oct 1; 310: 26–36. Published online 2020 Aug 10. doi: 10.1016/j.atherosclerosis.2020.07.030

PMCID:: PMC7116265

Abstract Article PDF–1.6M

Select item 70572587.

Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation

Alicia Mayeuf-Louchart, Steve Lancel, Yasmine Sebti, Benoit Pourcet, Anne Loyens, Stéphane Delhaye, Christian Duhem, Justine Beauchamp, Lise Ferri, Quentin Thorel, Alexis Boulinguiez, Mathilde Zecchin, Julie Dubois-Chevalier, Jérôme Eeckhoute, Logan T. Vaughn, Peter J. Roach, Christian Dani, Bartholomew A. Pederson, Stéphane D. Vincent, Bart Staels, Hélène Duez

Cell Rep. 2019 Nov 5; 29(6): 1410–1418.e6. Published online 2019 Nov 5. doi: 10.1016/j.celrep.2019.09.073

PMCID:: PMC7057258

Abstract Article

Select item 70245688.

DGAT1 DEFICIENCY DISRUPTS LYSOSOME FUNCTION IN ENTEROCYTES DURING DIETARY FAT ABSORPTION

Yu-Han Hung, Kimberly K. Buhman

Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2020 Apr 1.

Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Apr; 1864(4): 587–595. Published online 2018 Oct 17. doi: 10.1016/j.bbalip.2018.10.007

PMCID:: PMC7024568

Abstract Article PDF–1.8M

Select item 66555519.

WDFY4 is required for cross-presentation in response to viral and tumor antigens

Derek J. Theisen, Jesse T. Davidson, IV, Carlos G. Briseño, Marco Gargaro, Elvin J. Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R. Brickner, Wandy L. Beatty, Herbert W. Virgin, William E. Gillanders, Nima Mosammaparast, Michael S. Diamond, L. David Sibley, Wayne Yokoyama, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy

Science. Author manuscript; available in PMC 2019 Jul 24.

Published in final edited form as: Science. 2018 Nov 9; 362(6415): 694–699. doi: 10.1126/science.aat5030

PMCID:: PMC6655551

Abstract Article PDF–1020K

Select item 638665610.

DGAT1 inhibits retinol-dependent regulatory T cell formation and mediates autoimmune encephalomyelitis

Kareem L. Graham, Bonnie J. Werner, Kimberly M. Moyer, Alycia K. Patton, Charles R. Krois, Hong Sik Yoo, Maria Tverskoy, Melissa LaJevic, Joseph L. Napoli, Raymond A. Sobel, Brian A. Zabel, Eugene C. Butcher

Proc Natl Acad Sci U S A. 2019 Feb 19; 116(8): 3126–3135. Published online 2019 Feb 4. doi: 10.1073/pnas.1817669116

PMCID:: PMC6386656

Abstract Article PDF–1.4M

Select item 631425811.

Hepatic VLDL secretion: DGAT1 determines particle size but not particle number, which can be supported entirely by DGAT2

Zehra Irshad, Nikola Chmel, Raghu Adya, Victor A. Zammit

J Lipid Res. 2019 Jan; 60(1): 111–120. Published online 2018 Nov 5. doi: 10.1194/jlr.M089300

PMCID:: PMC6314258

Abstract Article PDF–952K

Select item 619522612.

Triglyceride Synthesis by DGAT1 Protects Adipocytes from Lipid-Induced ER Stress during Lipolysis

Chandramohan Chitraju, Niklas Mejhert, Joel T. Haas, L. Grisell Diaz-Ramirez, Carrie A. Grueter, Jason E. Imbriglio, Shirly Pinto, Suneil K. Koliwad, Tobias C. Walther, Robert V. Farese, Jr

Cell Metab. Author manuscript; available in PMC 2018 Oct 19.

Published in final edited form as: Cell Metab. 2017 Aug 1; 26(2): 407–418.e3. doi: 10.1016/j.cmet.2017.07.012

PMCID:: PMC6195226

Abstract Article PDF–2.7M

Select item 586287913.

The Role of Diacylglycerol Acyltransferase (DGAT) 1 and 2 in Cardiac Metabolism and Function

Nathan D. Roe, Michal K. Handzlik, Tao Li, Rong Tian

Sci Rep. 2018; 8: 4983. Published online 2018 Mar 21. doi: 10.1038/s41598-018-23223-7

PMCID:: PMC5862879

Abstract Article PDF–2.0M

Select item 555361314.

DGAT1-dependent lipid droplet biogenesis protects mitochondrial function during starvation-induced autophagy

Truc B. Nguyen, Sharon M. Louie, Joseph R. Daniele, Quan Tran, Andrew Dillin, Roberto Zoncu, Daniel K. Nomura, James A. Olzmann

Dev Cell. Author manuscript; available in PMC 2018 Jul 10.

Published in final edited form as: Dev Cell. 2017 Jul 10; 42(1): 9–21.e5. doi: 10.1016/j.devcel.2017.06.003

PMCID:: PMC5553613

Abstract Article PDF–2.2M

Select item 550321415.

Dgat1 and Dgat2 regulate enterocyte triacylglycerol distribution and alter proteins associated with cytoplasmic lipid droplets in response to dietary fat

Yu-Han Hung, Alicia L. Carreiro, Kimberly K. Buhman

Biochim Biophys Acta. Author manuscript; available in PMC 2018 Jun 1.

Published in final edited form as: Biochim Biophys Acta. 2017 Jun; 1862(6): 600–614. Published online 2017 Feb 27. doi: 10.1016/j.bbalip.2017.02.014

PMCID:: PMC5503214

Abstract Article PDF–2.0M

Select item 545450516.

Synthesis of neutral ether lipid monoalkyl-diacylglycerol by lipid acyltransferases

Zhengping Ma, Joelle M. Onorato, Luping Chen, David W. Nelson, Chi-Liang Eric Yen, Dong Cheng

J Lipid Res. 2017 Jun; 58(6): 1091–1099. Published online 2017 Apr 18. doi: 10.1194/jlr.M073445

PMCID:: PMC5454505

Abstract Article PDF–1.2M

Select item 536675617.

Analysis of Differentially Expressed Genes in Gastrocnemius Muscle between DGAT1 Transgenic Mice and Wild-Type Mice

Fei Ying, Hao Gu, Yuanzhu Xiong, Bo Zuo

Biomed Res Int. 2017; 2017: 5404682. Published online 2017 Mar 13. doi: 10.1155/2017/5404682

PMCID:: PMC5366756

Abstract Article PDF–957K

Select item 524252518.

Saturated fatty acids engage an IRE1α-dependent pathway to activate the NLRP3 inflammasome in myeloid cells

Megan M. Robblee, Charles C. Kim, Jess Porter Abate, Martin Valdearcos, Karin L.M. Sandlund, Meera Shenoy, Romain Volmer, Takao Iwawaki, Suneil K. Koliwad

Cell Rep. Author manuscript; available in PMC 2017 Jan 18.

Published in final edited form as: Cell Rep. 2016 Mar 22; 14(11): 2611–2623. Published online 2016 Mar 10. doi: 10.1016/j.celrep.2016.02.053

PMCID:: PMC5242525

Abstract Article PDF–1.1M

Select item 523470819.

Diacylglycerol acyltransferase 2 links glucose utilization to fatty acid oxidation in the brown adipocytes

Zehra Irshad, Federica Dimitri, Mark Christian, Victor A. Zammit

J Lipid Res. 2017 Jan; 58(1): 15–30. Published online 2016 Dec 29. doi: 10.1194/jlr.M068197

PMCID:: PMC5234708

Abstract Article PDF–1.6M

Select item 513335220.

Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation

Sandip K. Bose, Irina Hutson, Charles A. Harris

Endocrinology. 2016 Dec; 157(12): 4943–4960. Published online 2016 Oct 18. doi: 10.1210/en.2016-1615

PMCID:: PMC5133352

Abstract Article

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