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Select item 105658761.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 91197362.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 90036673.

CECR2 Drives Breast Cancer Metastasis by Promoting NF-κB Signaling and Macrophage-mediated Immune Suppression

Meiling Zhang, Zongzhi Z. Liu, Keisuke Aoshima, Wesley L. Cai, Hongyin Sun, Tianrui Xu, Yangyi Zhang, Yongyan An, Jocelyn F. Chen, Lok Hei Chan, Asako Aoshima, Sabine M. Lang, Zhenwei Tang, Xuanlin Che, Yao Li, Sara J. Rutter, Veerle Bossuyt, Xiang Chen, Jon S. Morrow, Lajos Pusztai, David. L. Rimm, Mingzhu Yin, Qin Yan

Sci Transl Med. Author manuscript; available in PMC 2022 Aug 2.

Published in final edited form as: Sci Transl Med. 2022 Feb 2; 14(630): eabf5473. Published online 2022 Feb 2. doi: 10.1126/scitranslmed.abf5473

PMCID:: PMC9003667

Abstract Article PDF–2.7M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78487055.

Discovery of a hidden transient state in all bromodomain families

Lluís Raich, Katharina Meier, Judith Günther, Clara D. Christ, Frank Noé, Simon Olsson

Proc Natl Acad Sci U S A. 2021 Jan 26; 118(4): e2017427118. Published online 2021 Jan 19. doi: 10.1073/pnas.2017427118

PMCID:: PMC7848705

Abstract Article PDF–1.9M

Select item 77712446.

NMR Analyses of Acetylated H2A.Z Isoforms Identify Differential Binding Interactions with the Bromodomain of the NURF Nucleosome Remodeling Complex

Noelle M. Olson, Samantha Kroc, Jorden A. Johnson, Huda Zahid, Peter D. Ycas, Alice Chan, Jennifer R. Kimbrough, Prakriti Kalra, Ernst Schönbrunn, William C. K. Pomerantz

Biochemistry. Author manuscript; available in PMC 2021 Apr 26.

Published in final edited form as: Biochemistry. 2020 May 26; 59(20): 1871–1880. Published online 2020 May 11. doi: 10.1021/acs.biochem.0c00159

PMCID:: PMC7771244

Abstract Article PDF–910K

Select item 69420447.

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity

Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller

Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119

PMCID:: PMC6942044

Abstract Article PDF–10M

Select item 61666828.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 50980429.

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells

Giorgio Oliviero, Gerard L. Brien, Ariane Waston, Gundula Streubel, Emilia Jerman, Darrell Andrews, Benjamin Doyle, Nayla Munawar, Kieran Wynne, John Crean, Adrian P. Bracken, Gerard Cagney

Mol Cell Proteomics. 2016 Nov; 15(11): 3450–3460. Published online 2016 Sep 15. doi: 10.1074/mcp.M116.062240

PMCID:: PMC5098042

Abstract Article PDF–1.9M

Select item 468531210.

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis

Giorgio Oliviero, Nayla Munawar, Ariane Watson, Gundula Streubel, Gwendolyn Manning, Vivian Bardwell, Adrian P. Bracken, Gerard Cagney

Sci Rep. 2015; 5: 18388. Published online 2015 Dec 21. doi: 10.1038/srep18388

PMCID:: PMC4685312

Abstract Article PDF–1.5M

Select item 429813811.

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination

Fade Gong, Li-Ya Chiu, Ben Cox, François Aymard, Thomas Clouaire, Justin W. Leung, Michael Cammarata, Mercedes Perez, Poonam Agarwal, Jennifer S. Brodbelt, Gaëlle Legube, Kyle M. Miller

Genes Dev. 2015 Jan 15; 29(2): 197–211. doi: 10.1101/gad.252189.114

PMCID:: PMC4298138

Abstract Article PDF–2.5M

Select item 412394412.

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover

David J. Elzi, Meihua Song, Kevin Hakala, Susan T. Weintraub, Yuzuru Shiio

J Proteome Res. 2014 Aug 1; 13(8): 3783–3791. Published online 2014 Jul 7. doi: 10.1021/pr500387m

PMCID:: PMC4123944

Abstract Article PDF–3.8M

Select item 388777513.

Genome-Wide Screen of Human Bromodomain-Containing Proteins Identifies Cecr2 as a Novel DNA Damage Response Protein

Seul-Ki Lee, Eun-Jung Park, Han-Sae Lee, Ye Seul Lee, Jongbum Kwon

Mol Cells. 2012 Jul 31; 34(1): 85–91. Published online 2012 Jun 12. doi: 10.1007/s10059-012-0112-4

PMCID:: PMC3887775

Abstract Article PDF–830K

Select item 347334914.

A de novo sSMC(22) Characterized by High-Resolution Arrays in a Girl with Cat-Eye Syndrome without Coloboma

C. Córdova-Fletes, M.G. Domínguez, A. Vázquez-Cárdenas, L.E. Figuera, V.A. Neira, A. Rojas-Martínez, R. Ortiz-López

Mol Syndromol. 2012 Sep; 3(3): 131–135. Published online 2012 Aug 1. doi: 10.1159/000341632

PMCID:: PMC3473349

Abstract Article PDF–339K

Select item 342112715.

A 600 kb triplication in the cat eye syndrome critical region causes anorectal, renal and preauricular anomalies in a three-generation family

Jeroen Knijnenburg, Yolande van Bever, Lorette O M Hulsman, Chantal A P van Kempen, Galhana M Bolman, Rosa Laura E van Loon, H Berna Beverloo, Laura J C M van Zutven

Eur J Hum Genet. 2012 Sep; 20(9): 986–989. Published online 2012 Mar 7. doi: 10.1038/ejhg.2012.43

PMCID:: PMC3421127

Abstract Article PDF–419K

Select item 338606916.

Functional genomics identifies therapeutic targets for MYC-driven cancer

Masafumi Toyoshima, Heather L. Howie, Maki Imakura, Ryan M. Walsh, James E. Annis, Aaron N. Chang, Jason Frazier, B. Nelson Chau, Andrey Loboda, Peter S. Linsley, Michele A. Cleary, Julie R. Park, Carla Grandori

Proc Natl Acad Sci U S A. 2012 Jun 12; 109(24): 9545–9550. Published online 2012 May 23. doi: 10.1073/pnas.1121119109