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Select item 111717061.

An Optimized Protocol for the Generation of Alveolospheres from Wild-Type Mice

Mahsa Zabihi, Ali Khadim, Theresa M. Schäfer, Ioannis Alexopoulos, Marek Bartkuhn, Elie El Agha, Ana I. Vazquez-Armendariz, Susanne Herold

Cells. 2024 Jun; 13(11): 922. Published online 2024 May 27. doi: 10.3390/cells13110922

PMCID:: PMC11171706

Abstract Article PDF–11M

Select item 111552642.

Lineage-specific intolerance to oncogenic drivers restricts histological transformation

Eric E. Gardner, Ethan M. Earlie, Kate Li, Jerin Thomas, Melissa J. Hubisz, Benjamin D. Stein, Chen Zhang, Lewis C. Cantley, Ashley M. Laughney, Harold Varmus

Science. Author manuscript; available in PMC 2024 Jun 6.

Published in final edited form as: Science. 2024 Feb 9; 383(6683): eadj1415. Published online 2024 Feb 9. doi: 10.1126/science.adj1415

PMCID:: PMC11155264

Abstract Article PDF–2.7M

Select item 111052183.

A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development

Amit Shrestha, Gianni Carraro, Nicolas Nottet, Ana Ivonne Vazquez-Armendariz, Susanne Herold, Julio Cordero, Indrabahadur Singh, Jochen Wilhelm, Guillermo Barreto, Rory Morty, Elie El Agha, Bernard Mari, Chengshui Chen, Jin-San Zhang, Cho-Ming Chao, Saverio Bellusci

Cell Mol Life Sci. 2019 Jul; 76(14): 2817–2832. Published online 2019 Mar 18. doi: 10.1007/s00018-019-03067-8

PMCID:: PMC11105218

Abstract Article PDF–20M

Select item 110991904.

CEBPA restricts alveolar type 2 cell plasticity during development and injury-repair

Dalia Hassan, Jichao Chen

Nat Commun. 2024; 15: 4148. Published online 2024 May 16. doi: 10.1038/s41467-024-48632-3

PMCID:: PMC11099190

Abstract Article PDF–11M

Select item 109333195.

Single-cell division tracing and transcriptomics reveal cell types and differentiation paths in the regenerating lung

Leila R. Martins, Lina Sieverling, Michelle Michelhans, Chiara Schiller, Cihan Erkut, Thomas G. P. Grünewald, Sergio Triana, Stefan Fröhling, Lars Velten, Hanno Glimm, Claudia Scholl

Nat Commun. 2024; 15: 2246. Published online 2024 Mar 12. doi: 10.1038/s41467-024-46469-4

PMCID:: PMC10933319

Abstract Article PDF–5.3M

Select item 109141226.

Lactate produced by alveolar type II cells suppresses inflammatory alveolar macrophages in acute lung injury

René M. Roy, Ayed Allawzi, Nana Burns, Christina Sul, Victoria Rubio, Jessica Graham, Kurt Stenmark, Eva S. Nozik, Rubin M. Tuder, Christine U. Vohwinkel

FASEB J. Author manuscript; available in PMC 2024 Mar 5.

Published in final edited form as: FASEB J. 2023 Dec; 37(12): e23316. doi: 10.1096/fj.202301722R

PMCID:: PMC10914122

Abstract Article PDF–2.5M

Select item 108396897.

Embigin deficiency leads to delayed embryonic lung development and high neonatal mortality in mice

Salli Talvi, Johanna Jokinen, Kalle Sipilä, Pekka Rappu, Fu-Ping Zhang, Matti Poutanen, Pia Rantakari, Jyrki Heino

iScience. 2024 Feb 16; 27(2): 108914. Published online 2024 Jan 15. doi: 10.1016/j.isci.2024.108914

PMCID:: PMC10839689

Abstract Article PDF–5.9M

Select item 106391658.

CD8 T cell response and its released cytokine IFN-γ are necessary for lung alveolar epithelial repair during bacterial pneumonia

Xiaoying Zhang, Mir Ali, Morgan Alexandra Pantuck, Xiaofeng Yang, Chih-Ru Lin, Karim Bahmed, Beata Kosmider, Ying Tian

Front Immunol. 2023; 14: 1268078. Published online 2023 Oct 26. doi: 10.3389/fimmu.2023.1268078

Correction in:: Front Immunol. 2024; 15: 1446350.

PMCID:: PMC10639165

Abstract Article PDF–2.6M

Select item 106217519.

Inducible tricolor reporter mouse for parallel imaging of lysosomes, mitochondria, and microtubules

Vera Hutchison, Anne Lynch, Andrés Mauricio Gutierrez-Gamez, Jichao Chen

J Cell Biol. 2024 Jan 1; 223(1): e202305086. Published online 2023 Nov 2. doi: 10.1083/jcb.202305086

PMCID:: PMC10621751

Abstract Article PDF–6.3M

Select item 1062005010.

ZSWIM8 destabilizes many murine microRNAs and is required for proper embryonic growth and development

Charlie Y. Shi, Lara E. Elcavage, Raghu R. Chivukula, Joanna Stefano, Benjamin Kleaveland, David P. Bartel

Genome Res. 2023 Sep; 33(9): 1482–1496. doi: 10.1101/gr.278073.123

PMCID:: PMC10620050

Abstract Article PDF–13M

Select item 1057813411.

Dysregulated tissue niche potentiates resident lymphocytes to suppress an interferon-sensitive stem cell reservoir in emphysema

Chaoqun Wang, Benjamin Hyams, Nancy C. Allen, Kelly Cautivo, Kiara Monahan, Minqi Zhou, Madelene W. Dahlgren, Carlos O. Lizama, Michael Matthay, Paul Wolters, Ari B. Molofsky, Tien Peng

Immunity. Author manuscript; available in PMC 2024 Mar 14.

Published in final edited form as: Immunity. 2023 Mar 14; 56(3): 576–591.e10. Published online 2023 Feb 22. doi: 10.1016/j.immuni.2023.01.032

PMCID:: PMC10578134

Abstract Article PDF–5.0M

Select item 1054548512.

DOT1L regulates lung developmental epithelial cell fate and adult alveolar stem cell differentiation after acute injury

Shanru Li, Derek Liberti, Su Zhou, Yun Ying, Jun Kong, Maria C. Basil, Fabian L. Cardenas-Diaz, Kazushige Shiraishi, Michael P. Morley, Edward E. Morrisey

Stem Cell Reports. 2023 Sep 12; 18(9): 1841–1853. Published online 2023 Aug 17. doi: 10.1016/j.stemcr.2023.07.006

PMCID:: PMC10545485

Abstract Article PDF–7.7M

Select item 1050917713.

Epithelial plasticity and innate immune activation promote lung tissue remodeling following respiratory viral infection

Andrew K. Beppu, Juanjuan Zhao, Changfu Yao, Gianni Carraro, Edo Israely, Anna Lucia Coelho, Katherine Drake, Cory M. Hogaboam, William C. Parks, Jay K. Kolls, Barry R. Stripp

Nat Commun. 2023; 14: 5814. Published online 2023 Sep 19. doi: 10.1038/s41467-023-41387-3

PMCID:: PMC10509177

Abstract Article PDF–7.1M

Select item 1047163514.

Autocrine TGF-β-positive feedback in profibrotic AT2-lineage cells plays a crucial role in non-inflammatory lung fibrogenesis

Yasunori Enomoto, Hiroaki Katsura, Takashi Fujimura, Akira Ogata, Saori Baba, Akira Yamaoka, Miho Kihara, Takaya Abe, Osamu Nishimura, Mitsutaka Kadota, Daisuke Hazama, Yugo Tanaka, Yoshimasa Maniwa, Tatsuya Nagano, Mitsuru Morimoto

Nat Commun. 2023; 14: 4956. Published online 2023 Aug 31. doi: 10.1038/s41467-023-40617-y

PMCID:: PMC10471635

Abstract Article PDF–3.8M

Select item 1044568815.

α7nAChR activation in AT2 cells promotes alveolar regeneration through WNT7B signaling in acute lung injury

Xiaoyan Chen, Cuiping Zhang, Tianchang Wei, Jie Chen, Ting Pan, Miao Li, Lu Wang, Juan Song, Cuicui Chen, Yan Zhang, Yuanlin Song, Xiao Su

JCI Insight. 2023 Aug 8; 8(15): e162547. Published online 2023 Aug 8. doi: 10.1172/jci.insight.162547

PMCID:: PMC10445688

Abstract Article PDF–3.9M

Select item 1039173116.

Tissue specificity of oncogenic BRAF targeted to lung and thyroid through a shared lineage factor

Elin Schoultz, Shawn Liang, Therese Carlsson, Stefan Filges, Anders Ståhlberg, Henrik Fagman, Clotilde Wiel, Volkan Sayin, Mikael Nilsson

iScience. 2023 Jul 21; 26(7): 107071. Published online 2023 Jun 8. doi: 10.1016/j.isci.2023.107071

PMCID:: PMC10391731

Abstract Article PDF–8.2M

Select item 1026438017.

Directed differentiation of mouse pluripotent stem cells into functional lung-specific mesenchyme

Andrea B. Alber, Hector A. Marquez, Liang Ma, George Kwong, Bibek R. Thapa, Carlos Villacorta-Martin, Jonathan Lindstrom-Vautrin, Pushpinder Bawa, Feiya Wang, Yongfeng Luo, Laertis Ikonomou, Wei Shi, Darrell N. Kotton

Nat Commun. 2023; 14: 3488. Published online 2023 Jun 13. doi: 10.1038/s41467-023-39099-9

PMCID:: PMC10264380

Abstract Article PDF–5.7M

Select item 1011242118.

Chronic Expression of a Clinical SFTPC Mutation Causes Murine Lung Fibrosis with Idiopathic Pulmonary Fibrosis Features

Luis Rodriguez, Yaniv Tomer, Paige Carson, Thalia Dimopoulos, Ming Zhao, Katrina Chavez, Swati Iyer, Li Huang, Christina Ebert, Larisa Sereda, Aditi Murthy, Glenda Trujillo, Michael F. Beers, Jeremy Katzen

Am J Respir Cell Mol Biol. 2023 Apr 1; 68(4): 358–365. Published online 2022 Dec 6. doi: 10.1165/rcmb.2022-0203MA

PMCID:: PMC10112421

Abstract Article PDF–1.7M

Select item 1011042319.

Sp3 is essential for normal lung morphogenesis and cell cycle progression during mouse embryonic development

Alyssa M. McCoy, Omar Lakhdari, Sayane Shome, Kaitlin Caoili, Gilberto E. Hernandez, Nima Aghaeepour, Lindsay D. Butcher, Kathleen Fisch, Lawrence S. Prince

Development. 2023 Mar 1; 150(5): dev200839. Published online 2023 Mar 3. doi: 10.1242/dev.200839