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Items: 1 to 20 of 90

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Immune predisposition drives susceptibility to pneumococcal pneumonia after mild influenza A virus infection in mice
Sunil Palani, Md Bashir Uddin, Michael McKelvey, Shengjun Shao, Keer Sun
Front Immunol. 2023; 14: 1272920. Published online 2023 Sep 13. doi: 10.3389/fimmu.2023.1272920
PMCID:
PMC10525308
AbstractArticlePDF–7.0M
3.
CSF2RB overexpression promotes the protective effects of mesenchymal stromal cells against ischemic heart injury
Tingting Qi, Xiaoming Xu, Yongzhen Guo, Yunlong Xia, Lu Peng, Congye Li, Fengyue Ding, Chao Gao, Miaomiao Fan, Min Yu, Huishou Zhao, Yuan He, Wenli Li, Chunxu Hai, Erhe Gao, Xing Zhang, Feng Gao, Yanhong Fan, Wenjun Yan, Ling Tao
Theranostics. 2023; 13(6): 1759–1773. Published online 2023 Mar 13. doi: 10.7150/thno.81336
PMCID:
PMC10091875
AbstractArticlePDF–7.4M
4.
Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE
Erwan Pernet, Sarah Sun, Nicole Sarden, Saideep Gona, Angela Nguyen, Nargis Khan, Martin Mawhinney, Kim A. Tran, Julia Chronopoulos, Dnyandeo Amberkar, Mina Sadeghi, Alexandre Grant, Shradha Wali, Renaud Prevel, Jun Ding, James G. Martin, Ajitha Thanabalasuriar, Bryan G. Yipp, Luis B. Barreiro, Maziar Divangahi
Nature. 2023; 614(7948): 530–538. Published online 2023 Jan 4. doi: 10.1038/s41586-022-05660-7
PMCID:
PMC9945843
AbstractArticlePDF–44M
5.
A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common β chain (CSF2RB) protein stability
Sebastian H.J. Koochaki, Mikołaj Słabicki, Ryan Lumpkin, Charles Zou, Roger Belizaire, Eric S. Fischer, Benjamin L. Ebert
J Biol Chem. 2022 Oct; 298(10): 102484. Published online 2022 Sep 13. doi: 10.1016/j.jbc.2022.102484
PMCID:
PMC9574515
AbstractArticlePDF–1.8M
6.
Role of GM-CSF in regulating metabolism and mitochondrial functions critical to macrophage proliferation
Matthew Wessendarp, Miki Watanabe-Chailland, Serena Liu, Traci Stankiewicz, Yan Ma, Rajesh K Kasam, Kenjiro Shima, Claudia Chalk, Brenna Carey, Lindsey-Romick Rosendale, Marie Dominique Filippi, Paritha Arumugam
Mitochondrion. Author manuscript; available in PMC 2022 Oct 16.
Published in final edited form as: Mitochondrion. 2022 Jan; 62: 85–101. Published online 2021 Nov 2. doi: 10.1016/j.mito.2021.10.009
PMCID:
PMC9573767
AbstractArticlePDF–1.6M
7.
Legionella-infected macrophages engage the alveolar epithelium to metabolically reprogram myeloid cells and promote antibacterial inflammation
Xin Liu, Mark A. Boyer, Alicia M. Holmgren, Sunny Shin
Cell Host Microbe. Author manuscript; available in PMC 2022 Jul 31.
Published in final edited form as: Cell Host Microbe. 2020 Nov 11; 28(5): 683–698.e6. Published online 2020 Aug 24. doi: 10.1016/j.chom.2020.07.019
PMCID:
PMC9339267
AbstractArticlePDF–2.9M
8.
CD4+ T helper 2 cells suppress breast cancer by inducing terminal differentiation
Margherita Boieri, Anna Malishkevich, Ranya Guennoun, Emanuela Marchese, Sanne Kroon, Kathryn E. Trerice, Mary Awad, Jong Ho Park, Sowmya Iyer, Johannes Kreuzer, Wilhelm Haas, Miguel N. Rivera, Shadmehr Demehri
J Exp Med. 2022 Jul 4; 219(7): e20201963. Published online 2022 Jun 3. doi: 10.1084/jem.20201963
PMCID:
PMC9170526
AbstractArticlePDF–9.3M
9.
The IL-3, IL-5, and GM-CSF common receptor beta chain mediates oncogenic activity of FLT3-ITD-positive AML
Anne Charlet, Max Kappenstein, Philip Keye, Kathrin Kläsener, Cornelia Endres, Teresa Poggio, Sivahari P. Gorantla, Stefanie Kreutmair, Jana Sänger, Anna L. Illert, Cornelius Miething, Michael Reth, Justus Duyster, Christoph Rummelt, Nikolas von Bubnoff
Leukemia. 2022; 36(3): 701–711. Published online 2021 Nov 8. doi: 10.1038/s41375-021-01462-4
PMCID:
PMC8885422
AbstractArticlePDF–2.2M
10.
Granulocyte Macrophage-Colony Stimulating Factor Produces a Splenic Subset of Monocyte-Derived Dendritic Cells That Efficiently Polarize T Helper Type 2 Cells in Response to Blood-Borne Antigen
Seul Hye Ryu, Hyun Soo Shin, Hye Hyeon Eum, Ji Soo Park, Wanho Choi, Hye Young Na, Hyunju In, Tae-Gyun Kim, Sejung Park, Soomin Hwang, Moah Sohn, Eun-Do Kim, Kyoung Yul Seo, Hae-Ock Lee, Min-Geol Lee, Min Kyung Chu, Chae Gyu Park
Front Immunol. 2021; 12: 767037. Published online 2022 Jan 3. doi: 10.3389/fimmu.2021.767037
PMCID:
PMC8778578
AbstractArticlePDF–11M
11.
Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient
Satomi Yogosawa, Makiko Ohkido, Takuro Horii, Yasumasa Okazaki, Jun Nakayama, Saishu Yoshida, Shinya Toyokuni, Izuho Hatada, Mitsuru Morimoto, Kiyotsugu Yoshida
Commun Biol. 2021; 4: 1204. Published online 2021 Oct 20. doi: 10.1038/s42003-021-02734-6
PMCID:
PMC8528819
AbstractArticlePDF–3.6M
12.
Natural killer cells and dendritic epidermal γδ T cells orchestrate type 1 conventional DC spatiotemporal repositioning toward CD8+ T cells
Sonia Ghilas, Marc Ambrosini, Jean-Charles Cancel, Carine Brousse, Marion Massé, Hugues Lelouard, Marc Dalod, Karine Crozat
iScience. 2021 Sep 24; 24(9): 103059. Published online 2021 Aug 28. doi: 10.1016/j.isci.2021.103059
PMCID:
PMC8449251
AbstractArticlePDF–4.0M
13.
Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes
Liliana M. Sanmarco, Michael A. Wheeler, Cristina Gutiérrez-Vázquez, Carolina Manganeli Polonio, Mathias Linnerbauer, Felipe A. Pinho-Ribeiro, Zhaorong Li, Federico Giovannoni, Katelyn V. Batterman, Giulia Scalisi, Stephanie E. J. Zandee, Evelyn S. Heck, Moneera Alsuwailm, Douglas L. Rosene, Burkhard Becher, Isaac M. Chiu, Alexandre Prat, Francisco J. Quintana
Nature. Author manuscript; available in PMC 2021 Aug 1.
Published in final edited form as: Nature. 2021 Feb; 590(7846): 473–479. Published online 2021 Jan 6. doi: 10.1038/s41586-020-03116-4
PMCID:
PMC8039910
AbstractArticlePDF–6.3M
14.
Limited proliferation capacity of aorta intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression
Jesse W. Williams, Konstantin Zaitsev, Ki-Wook Kim, Stoyan Ivanov, Brian T. Saunders, Patricia R. Schrank, Kyeongdae Kim, Andrew Elvington, Seung Hyeon Kim, Christopher G. Tucker, Mary Wohltmann, Brian T. Fife, Slava Epelman, Maxim N. Artyomov, Kory J. Lavine, Bernd H. Zinselmeyer, Jae-Hoon Choi, Gwendalyn J. Randolph
Nat Immunol. Author manuscript; available in PMC 2021 Mar 7.
Published in final edited form as: Nat Immunol. 2020 Oct; 21(10): 1194–1204. Published online 2020 Sep 7. doi: 10.1038/s41590-020-0768-4
PMCID:
PMC7502558
AbstractArticlePDF–7.2M
15.
Microglial Homeostasis Requires Balanced CSF-1/CSF-2 Receptor Signaling
Violeta Chitu, Fabrizio Biundo, Gabriel G.L. Shlager, Eun S. Park, Ping Wang, Maria E. Gulinello, Sxölen Gokhan, Harmony C. Ketchum, Kusumika Saha, Michael A. DeTure, Dennis W. Dickson, Zbignew K. Wszolek, Deyou Zheng, Andrew L. Croxford, Burkhard Becher, Daqian Sun, Mark F. Mehler, E. Richard Stanley
Cell Rep. Author manuscript; available in PMC 2020 Jul 20.
Published in final edited form as: Cell Rep. 2020 Mar 3; 30(9): 3004–3019.e5. doi: 10.1016/j.celrep.2020.02.028
PMCID:
PMC7370656
AbstractArticlePDF–3.7M
16.
Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection
Cedric Bosteels, Katrijn Neyt, Manon Vanheerswynghels, Mary J. van Helden, Dorine Sichien, Nincy Debeuf, Sofie De Prijck, Victor Bosteels, Niels Vandamme, Liesbet Martens, Yvan Saeys, Els Louagie, Manon Lesage, David L. Williams, Shiau-Choot Tang, Johannes U. Mayer, Franca Ronchese, Charlotte L. Scott, Hamida Hammad, Martin Guilliams, Bart N. Lambrecht
Immunity. 2020 Jun 16; 52(6): 1039–1056.e9. Published online 2020 May 8. doi: 10.1016/j.immuni.2020.04.005
PMCID:
PMC7207120
AbstractArticlePDF–9.6M
17.
NK cell–derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS
Cynthia Louis, Fernando Souza- Fonseca-Guimaraes, Yuyan Yang, Damian D’Silva, Tobias Kratina, Laura Dagley, Soroor Hediyeh-Zadeh, Jai Rautela, Seth Lucian Masters, Melissa J. Davis, Jeffrey J. Babon, Bogoljub Ciric, Eric Vivier, Warren S. Alexander, Nicholas D. Huntington, Ian P. Wicks
J Exp Med. 2020 May 4; 217(5): e20191421. Published online 2020 Feb 25. doi: 10.1084/jem.20191421
Correction in:
J Exp Med. 2020 May 4; 217(5): e2019142103192020c.
PMCID:
PMC7201918
AbstractArticlePDF–5.0M
18.
Granulocyte-Macrophage Colony Stimulating Factor As an Indirect Mediator of Nociceptor Activation and Pain
Damini Tewari, Andrew D. Cook, Ming-Chin Lee, Anne D. Christensen, Andrew Croxford, Burkhard Becher, Daniel Poole, Pradeep Rajasekhar, Nigel Bunnett, Julia E. Smith, John A. Hamilton, Stephen B. McMahon
J Neurosci. 2020 Mar 11; 40(11): 2189–2199. doi: 10.1523/JNEUROSCI.2268-19.2020
PMCID:
PMC7083288
AbstractArticlePDF–785K
19.
BHLHE40 promotes TH2 cell-mediated anti-helminth immunity and reveals cooperative CSF2RB family cytokines
Nicholas N. Jarjour, Tara R. Bradstreet, Elizabeth A. Schwarzkopf, Melissa E. Cook, Chin-Wen Lai, Stanley Ching-Cheng Huang, Reshma Taneja, Thaddeus S. Stappenbeck, Steven J. Van Dyken, Joseph F. Urban, Jr., Brian T. Edelson
J Immunol. Author manuscript; available in PMC 2021 Feb 15.
Published in final edited form as: J Immunol. 2020 Feb 15; 204(4): 923–932. Published online 2020 Jan 3. doi: 10.4049/jimmunol.1900978
PMCID:
PMC7002269
AbstractArticlePDF–1.9M
20.
Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self‐renewal and identity
René Rauschmeier, Charlotte Gustafsson, Annika Reinhardt, Noelia A‐Gonzalez, Luigi Tortola, Dilay Cansever, Sethuraman Subramanian, Reshma Taneja, Moritz J Rossner, Michael H Sieweke, Melanie Greter, Robert Månsson, Meinrad Busslinger, Taras Kreslavsky
EMBO J. 2019 Oct 1; 38(19): e101233. Published online 2019 Aug 15. doi: 10.15252/embj.2018101233
PMCID:
PMC6769426
AbstractArticlePDF–1.9M

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