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Select item 111896331.

E3 ubiquitin ligase Deltex facilitates the expansion of Wingless gradient and antagonizes Wingless signaling through a conserved mechanism of transcriptional effector Armadillo/β-catenin degradation

Vartika Sharma, Nalani Sachan, Bappi Sarkar, Mousumi Mutsuddi, Ashim Mukherjee

eLife. 2024; 12: RP88466. Published online 2024 Jun 20. doi: 10.7554/eLife.88466

PMCID:: PMC11189633

Abstract Article PDF–13M

Select item 111181772.

The First Defined Null Allele of the Notch Regulator, a Suppressor of Deltex: Uncovering Its Novel Roles in Drosophila melanogaster Oogenesis

Marian B. Wilkin, Rory Whiteford, Tanveer Akbar, Samira Hosseini-Alghaderi, Raluca Revici, Ann-Marie Carbery, Martin Baron

Biomolecules. 2024 May; 14(5): 522. Published online 2024 Apr 26. doi: 10.3390/biom14050522

PMCID:: PMC11118177

Abstract Article PDF–22M

Select item 110395293.

Regulation of Notch signaling by non-muscle myosin II Zipper in Drosophila

Dipti Verma, Ankita Singh, Jyoti Singh, Mousumi Mutsuddi, Ashim Mukherjee

Cell Mol Life Sci. 2024 Dec; 81(1): 195. Published online 2024 Apr 24. doi: 10.1007/s00018-024-05142-1

PMCID:: PMC11039529

Abstract Article PDF–10M

Select item 108684004.

Alternative mechanisms of Notch activation by partitioning into distinct endosomal domains

Hideyuki Shimizu, Samira Hosseini-Alghaderi, Simon A. Woodcock, Martin Baron

J Cell Biol. 2024 May 6; 223(5): e202211041. Published online 2024 Feb 15. doi: 10.1083/jcb.202211041

PMCID:: PMC10868400

Abstract Article PDF–5.9M

Select item 106476825.

Signaling Pathways Controlling Axonal Wrapping in Drosophila

Marie Baldenius, Steffen Kautzmann, Suchet Nanda, Christian Klämbt

Cells. 2023 Nov; 12(21): 2553. Published online 2023 Oct 31. doi: 10.3390/cells12212553

PMCID:: PMC10647682

Abstract Article PDF–4.3M

Select item 103940046.

Wg/Wnt1 and Erasp link ER stress to proapoptotic signaling in an autosomal dominant retinitis pigmentosa model

Jung-Eun Park, Jiyoun Lee, Soonhyuck Ok, Seunghee Byun, Eun-Ju Chang, Sung-Eun Yoon, Young-Joon Kim, Min-Ji Kang

Exp Mol Med. 2023 Jul; 55(7): 1544–1555. Published online 2023 Jul 18. doi: 10.1038/s12276-023-01044-7

PMCID:: PMC10394004

Abstract Article PDF–3.8M

Select item 103380787.

Structural features of the Notch ankyrin domain-Deltex WWE₂ domain heterodimer determined by NMR spectroscopy and functional implications

Andrea A. Carter, Kristen M. Ramsey, Christine L. Hatem, Kathryn P. Sherry, Ananya Majumdar, Doug Barrick

Structure. Author manuscript; available in PMC 2024 May 4.

Published in final edited form as: Structure. 2023 May 4; 31(5): 584–594.e5. Published online 2023 Mar 27. doi: 10.1016/j.str.2023.03.003

PMCID:: PMC10338078

Abstract Article PDF–2.2M

Select item 101057368.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 91015079.

Endocytosis at the Crossroad of Polarity and Signaling Regulation: Learning from Drosophila melanogaster and Beyond

Fani Papagiannouli

Int J Mol Sci. 2022 May; 23(9): 4684. Published online 2022 Apr 23. doi: 10.3390/ijms23094684

PMCID:: PMC9101507

Abstract Article PDF–3.6M

Select item 896160810.

E3 Ubiquitin Ligase Regulators of Notch Receptor Endocytosis: From Flies to Humans

Raluca Revici, Samira Hosseini-Alghaderi, Fabienne Haslam, Rory Whiteford, Martin Baron

Biomolecules. 2022 Feb; 12(2): 224. Published online 2022 Jan 27. doi: 10.3390/biom12020224

PMCID:: PMC8961608

Abstract Article PDF–2.0M

Select item 890868611.

Ubiquitylation is required for the incorporation of the Notch receptor into intraluminal vesicles to prevent prolonged and ligand-independent activation of the pathway

Björn Schnute, Hideyuki Shimizu, Marvin Lyga, Martin Baron, Thomas Klein

BMC Biol. 2022; 20: 65. Published online 2022 Mar 10. doi: 10.1186/s12915-022-01245-y

PMCID:: PMC8908686

Abstract Article PDF–10M

Select item 866448612.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 846605813.

The Role of Intracellular Trafficking of Notch Receptors in Ligand-Independent Notch Activation

Judith Hounjet, Marc Vooijs

Biomolecules. 2021 Sep; 11(9): 1369. Published online 2021 Sep 16. doi: 10.3390/biom11091369

PMCID:: PMC8466058

Abstract Article PDF–2.2M

Select item 817247614.

Interplay between sex determination cascade and major signaling pathways during Drosophila eye development: perspectives for future research

Svetlana Surkova, Jessica Görne, Sergey Nuzhdin, Maria Samsonova

Dev Biol. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: Dev Biol. 2021 Aug; 476: 41–52. Published online 2021 Mar 18. doi: 10.1016/j.ydbio.2021.03.005

PMCID:: PMC8172476

Abstract Article PDF–2.0M

Select item 775459715.

Lethal (2) giant discs (Lgd)/CC2D1 is required for the full activity of the ESCRT machinery

Miriam Baeumers, Kristina Ruhnau, Thomas Breuer, Hendrik Pannen, Bastian Goerlich, Anna Kniebel, Sebastian Haensch, Stefanie Weidtkamp-Peters, Lutz Schmitt, Thomas Klein

BMC Biol. 2020; 18: 200. Published online 2020 Dec 22. doi: 10.1186/s12915-020-00933-x